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83 articles for “Bacterial resistance”
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Properties and antimicrobial activity of bacterial nanocellulose composite incorporated with silver nanoparticles based on green synthesis
Abstract: Green silver nanoparticles (AgNPs) synthesized using medical plant extracts as capping and reducing agents demonstrate broad applicability in addressing the threat posed by infections. In this study, we present a sustainable, low-toxicity, and cost-effective bacterial nanocellulose composite with silver nanoparticles based on green synthesis that uses Origanum vulgare as a reducing agent due to numerous biological components. The formation of AgNPs in composite and morphological properties was analyzed using scanning …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 323–328 Read article
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Plant Bioactive Metabolites and Their Role in the Prevention and Control of Dental Diseases and Infections.
Abstract: The oral diseases, including dental caries and periodontitis, affect masses worldwide, and have historically been managed with synthetic antimicrobials that cause deleterious side effects, leading to mounting bacterial resistance. Consequently, contemporary dentistry is rapidly shifting toward phytomedicine using plant bioactive molecules, such as polyphenols, terpenes, anthraquinones (berberin, eugenol, curcumin, catechins, allicin, and azadirachtin. These compounds offer potent antimicrobial, anti-inflammatory, and tissue-regenerative properties that are crucial for preventing and curing dental …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 47–66 Read article
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Meta-Analysis on Antibiotic Resistance and Its Irrational Use in India: Need of Antibiotic Stewardship Program Implementation
Abstract: Antibiotic resistance is a major health issue in developing countries. This issue is increasing exponentially due to increased consumption, easy availability of medicine and higher incidence of inappropriate use. Moreover, India stands as one among the highest infectious disease burdened country in the world. This study aims to conduct a statistical analysis to find the association between antibiotic resistance and its irrational use in India. Thereby, emphasizing the need for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 6–14 Read article
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Herbal Frontiers: The Role of Alternative Remedies in Combating Typhoid Fevers
Abstract: Typhoid fever, caused by Salmonella typhi, remains a major health challenge, particularly in developing regions where sanitation and healthcare resources are limited. With an estimated global incidence of 17 million cases annually, the disease poses a significant public health burden. The growing resistance to conventional antibiotics, such as fluoroquinolones and third-generation cephalosporins, exacerbates treatment challenges. This has spurred interest in alternative remedies, including herbal and homeopathic treatments.Herbal medicine offers a …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Role of Therapeutic Index for Local Infections Score in Wound Assessment
Abstract: Local wound infections pose a significant challenge, often detected later, leading to complications like systemic infections. Global nomenclature lacks uniformity, resulting in varied treatments for similar diagnoses. Early intervention is crucial, advocating for local antimicrobial therapy with diverse active agents to avoid systemic antibiotics and mitigate bacterial resistance. The Therapeutic Index for Local Infections (TILI) score, innovated by the German society Initiative Chronis Che Wenden (ICW), emerges as a pivotal …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 44–48 Read article
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Antibacterial Activities of Medicinal Plant Leaves Extract Against Isolated Escherichia coli Bacteria from Different Water Sources
Abstract: Objective: Escherichia coli are the most common pathogenic bacteria to accountable for food and waterborne illness. Therefore, in this way the study was conducted to resolve the occurrence of E. coli bacteria from different water sources in around Tamil Nadu along with to determine their antibiotic resistance profiles. Methods: Water samples were analysed for the presence of E. coli bacteria using specific agar media Eosin Methylene Blue and McConkeys. Colony …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article
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Antibiotic Resistance: Molecular Mechanisms of Resistance
Abstract: Antibiotics are called as ‘Wonder Drugs’, the miracles of modern sciences. They help combat bacteria and prevent their growth. But due to unmonitored and uncontrolled consumption of these antibiotics, there is an emergence of antibiotic resistance. This has led to a series of downfall in the therapeutic potency and efficacy of many drugs. More and more bacteria are becoming Multi-Drug Resistant (MDR); such highly resistant strains of certain bacteria are …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article
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Synergistic and Antagonistic Effects of Azo-Schiff Base with Some Antibiotics on Gram-Positive Bacterial Isolates
Abstract: Antibacterial resistance has brought an urgent need to find a solution to the problem of antibacterial resistance and increase the effectiveness of antibiotics. Therefore, our current study was aimed to test the three concentrations viz., 0.5 mg/ml, 5 mg/ml and 50 mg/ml of Azo-Schiff base against Grampositive bacteria—Bacillus cereus, Micrococcus lutes, Staphylococcus aureus—to compare the effects of Schiff base alone or along with antibiotics on the viability of bacteria. Our …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 2, 2021 · pp. 25–31 Read article
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Whispers of the Microbial World: Unveiling Bacterial Dialogues through Quorum Sensing
Abstract: Quorum sensing is a special way of bacteria by which they can regulate their own gene expression as per the population density of the bacteria. It is basically a type of cell-to-cell communication pathway used by the microbes. The signal molecule which helps in this mechanism are called auto inducer(AI). As the mechanism depends by changes in the cell density, so when the cell density reaches to the threshold cell …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Chompound contaning oxadiazole derivatives and their potential therapeutic uses.
Abstract: Derivatives of oxadiazole or furadi azole rings constitute a significant class of heterocyclic substances. Oxadiazole is a heterocyclic, five-membered ring with two carbons, one oxygen atom, two nitrogen atoms, and two double bonds. They are produced by substituting two nitrogen (-N =) atoms for two methylene groups (= CH) in furan. The furan ring's aromaticity was significantly decreased by substituting these groups, resulting in a conjugated diene character. There were …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 68–74 Read article
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Zinc Oxide Nanoparticles from Murayya koenigii: Antibacterial Potential Review
Abstract: Nanoparticles (NPs) display unique characteristics in contrast to conventional physico-chemical synthesis methods, and they are utilized in various life science fields including surface coating, catalysis, food packaging, corrosion prevention, environmental cleanup, electronics, biomedical applications, and antimicrobial purposes. Metal NPs synthesized through green methods, particularly from plant origins, have garnered significant interest because of their inherent traits such as environmental friendliness, quick production, and cost efficiency. Over the past few years, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 54–67 Read article
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Zn Doped CuO Nanoparticles for Increasing the Longevity of The Agricultural Products †
Abstract: Nanotechnology is an enabling technology at the service of mankind. Indeed, enhancing the long-term storage of agricultural products (post-harvest during transportation and storage) in general and apples and tomatoes, in particular, is a challenge. Zn-doped CuO is a proven nanomaterial with special ability to kill plant pathogens as well as a variety of microorganisms (bacteria, virus, and fungus). Much of the review is focused on the landmark papers published by …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 14–29 Read article
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Bacterial Spectral in UTI in a Hospital Environment
Abstract: Urinary tract infections (UTIs) represent a significant public health issue, primarily caused by a variety of pathogens such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis, and Staphylococcus saprophyticus. UTIs contribute substantially to illness and complications in individuals with pre-existing health conditions and account for a large portion of hospital visits globally. UTIs are usually self-limiting in people with no structural or functional problems, but they do tend to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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Biological Synthesis of Silver Nanoparticles Using Hibiscus Sabdariffa Leaf Extract and It’s Antibacterial Sensitivity Assay
Abstract: In this study, AgNO3 was effectively used to synthesize silver nanoparticles. Hibiscus sabdariffa leaf extract was used to promptly and easily synthesize silver nanoparticles. An UV-Visible spectrophotometer showed absorbance peak in range of 300-600 nm. The procedure was found to be easy to follow, quick, least step and safe for the environment. It is non-toxic, and a viable substitute for traditional physical or chemical procedures. At room temperature, silver ions …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 08–13 Read article
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Extended-spectrum beta-lactamases (ESBLs) and Metallo-beta-lactamases (MBLs): A Review
Abstract: Gram-negative bacteria produce extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs), enzymes that play a crucial role in antibiotic resistance. These enzymes enable the bacteria to withstand a wide array of beta-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. The production of these enzymes, particularly by organisms, such as Escherichia coli and Klebsiella pneumoniae, complicates treatment options for severe infections, leading to increased morbidity and mortality in clinical settings. ESBLs are primarily responsible …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 8–19 Read article
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The Burden of Empirical Therapy: Analyzing the Predominance of Broad-Spectrum Antibiotic Usage in Lower Respiratory Tract Infections
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Application of Some Essential Bacterial Probiotics in Aquaculture: A Review
Abstract: Aquaculture plays an essential role in maintaining food security and sustainable lives for the world’s ever-growing population. Due to the expansion, intensification, and variety of aquaculture methods, aquatic animals confront significant challenges, including disease outbreaks, decreasing output, and risks to the sustainability of the sector. Poor soil conditions in aquaculture cause higher mortality, a higher prevalence of diseases, and lower yields of aquatic organisms. Overfeeding, dead animals, and feces from …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 22–30 Read article
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A study on Antibiotic Resistance: An Analysis of Molecular Mechanisms and Therapeutic Implications
Abstract: Antibiotic resistance (AR) represents one of the most critical existential threats to global public health, rapidly eroding the efficacy of established antimicrobial therapies and portending a return to the pre-antibiotic era. This analysis explores the intricate molecular landscape defining this crisis, focusing specifically on the primary mechanisms of action (MoA) utilized by major antibiotic classes—including cell wall inhibitors, protein synthesis inhibitors, and nucleic acid synthesis inhibitors—and the corresponding, diverse mechanisms …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 9–21 Read article
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Edible Mushrooms: Management of Diabetes Mellitus and Phytochemical Screening of Agaricus Bisporus
Abstract: A metabolic disease characterized by elevated blood glucose levels; diabetes mellitus affects millions of people. If not treated on time, it causes problems, damage organs, and even life-threatening. Studies have shown that diabetes can be avoided and controlled with a healthy lifestyle that incorporates exercise and a balanced diet. While there are several synthetic medications available to treat this illness using them over an extended period of time is linked …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 1–13 Read article
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Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable Therapeutics
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article