Search
646 articles for “T cells”
-
Immunotherapy Advancements in Cancer Treatment
Abstract: Immuno-oncology has been one of the more exciting developments in the field of cancer treatment since about a century ago, with William B. Coley's work in the late 19th century, which really gave the field its beginnings with "Coley's toxin." In an initial effort that proved unsuccessful, early immunotherapy approaches utilizing bacterial mixtures to induce immune responses against tumors nonetheless laid some groundwork for this field. It wasn't until over …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 22–28 Read article
-
Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article
-
The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
-
Need For EPDS in Indian High-Rise Constructions for Reduced Greenwashing and Sustainable Future with Green Polymer and Composites
Abstract: Environmental product declarations (EPDs) are a globally recognized means of communicating the environmental impacts of a product or service across its entire lifecycle. They evaluate various items' environmental performance and pinpoint enhancement chances. EPDs are very useful in the construction industry since they may be used to choose environmentally friendly building materials and techniques. India is undergoing a swift construction surge, with high-rise towers becoming progressively prevalent.. However, the construction …
Published in Journal of Polymer & Composites · Vol. 12, Issue 7, 2024 · pp. 54–66 Read article
-
Non-Enzymatic Glycation in Alzheimer’s and Parkinson’s Disease: A Molecular Approach to Pathology and Recent Advances
Abstract: Non-enzymatic glycation, a biochemical process by which reducing sugars spontaneously bind to proteins, leads to the formation of advanced glycation end-products (AGEs), which have emerged as critical contributors to the pathogenesis of several neurodegenerative diseases, particularly Alzheimer’s disease (AD) and Parkinson’s disease (PD). The accumulation of AGEs can significantly alter protein structure, stability, and function, triggering a cascade of detrimental effects, including increased oxidative stress, heightened neuroinflammation, and the promotion …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 36–41 Read article
-
Is Hydrogen the Future of the Automotive Sector? A Critical Overview
Abstract: The transition towards sustainable energy sources in the automotive sector has become imperative in light of escalating environmental challenges and the depletion of fossil fuels. Among alternative energy solutions, hydrogen has emerged as a promising candidate due to its high energy density, zero-emission potential, and technological advancements in fuel cell systems. This review critically examines the viability of hydrogen as a dominant energy source for future automotive applications. The paper …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 15, Issue 3, 2024 · pp. 35–43 Read article
-
Na-Air Battery: The Battery of the Future—A Review
Abstract: Metal-ion batteries came into the limelight with the invention of Zn-ion battery as early as 1878, but its commercial viability came into picture in 1990 and lithium-ion cell in 1977. Since then, a number of metals have been experimented upon and similar rechargeable secondary storage batteries like Al-ion, Na-ion, Sn-ion, Mg-ion, K-ion have been developed. In this type of battery, electrochemical dynamics involves the movement of only one kind of …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 15, Issue 3, 2024 · pp. 1–19 Read article
-
Towards smart cancer care - AI enhanced monitoring and intervention
Abstract: According to estimates from the World Health Organization (WHO) for 2022, cancer is one of the leading causes of mortality, accounting for roughly 16% of all deaths globally. The goal of the cancer community is to improve the lives of those who are impacted by cancer and to cut the cancer death rate in half during the next several years. If cancer is identified early and treated, its impact on …
Published in Journal of Microwave Engineering and Technologies · Vol. 12, Issue 1, 2025 · pp. 38–44 Read article
-
Nutraceuticals as Adjunctive Treatment in Cancer Exploring Efficacy and Mechanism of Action
Abstract: Dietary habits are a critical factor in cancer prevention, with plant-based diets rich in vegetables and fruits associated with reduced cancer risk. Nutraceuticals—bioactive compounds derived from food and supplements—have gained attention for their potential in cancer prevention and therapy. Phytochemicals such as flavonoids, polyphenols, and alkaloids exhibit anti-cancer properties through mechanisms including antioxidant activity, anti-inflammatory effects, inhibition of tumor growth, and induction of apoptosis. Key nutraceuticals include alkaloids (e.g., caffeine, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 35–45 Read article
-
Brain Tumor Detection Through CNN: Techniques, Dataset Insights, and Methodology
Abstract: Computer technologies are playing huge roles in some areas of the medical domain like surgery and therapy of different diseases. Researchers are doing studies and trying to experiment to detect different diseases like cancer, virus infections, and leprosy. There are many different medical imaging datasets that are publicly available for medical research purposes of diseases like cancer, virus infections, and leprosy, etc. where we can be able to access large …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 30–40 Read article
-
Integrated Plasma Gasification Technologies for Enhanced Energy Conversion and Environmental Sustainability: A Short Review
Abstract: Plasma Gasification emerged as a constructive tool for waste management and cleaner energy production. The versatility of the process makes it a promising solution of the global energy crises. In this paper, a brief coverup is done of integrated plasma models. Plasma technology is an emerging solution for recycling a wide range of waste making it a highly sustainable, efficient, and environment-friendly process. The integration of Plasma Gasification with complementary …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 67–75 Read article
-
Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
-
Experimental Investigation and Surface Morphology Study on Areca Fiber Composite Material
Abstract: Composites manufactured from areca fibers had their characteristics assessed in recent research. Shape and size were determined by cutting the stem. It takes six months to dry the fibers once they are taken from the tree stem. Because pectin, cellulose, hemicellulose, and lignin make up the bulk of it. It has great regeneration capacity and is a resource material made of wood fibers. The untreated and chemically treated fibers are …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 459–468 Read article
-
Neurodegeneration and Cognitive Decline: Causes, Consequences, and Treatment Approaches
Abstract: Neurodegenerative diseases gradually destroy nerve cells, often leading to fatal outcomes. The phrase includes a wide range of clinical problems, such as a variety of Neurological conditions include movement disorders, like Parkinson’s disease (PD) and progressive cognitive impairments, with Alzheimer’s disease (AD) being the most common among them. A loss of neurones and synaptic connections, typically in later life, is a prevalent feature of Usually, the onset and development of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 47–59 Read article
-
Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
-
Review on Sustained Released Matrix Tablet
Abstract: Pharmaceuticals often use sustained release dose forms to prolong the therapeutic agent’s presence in the bloodstream and maintain a consistent plasma profile. The matrix governs the drug’s release rate. Hydroxypropyl methyl cellulose, a release retardant, is a key excipient in formulations due to its ability to promote sustained release. Techniques that include wet granulation, direct compression, or the dispersion of solid particles within a porous matrix, integrating polymers, like polymethyl …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 60–69 Read article
-
Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
-
Nurse’s Responsibility and Liability in Chemotherapy Formulation: Legal and Ethical Considerations
Abstract: Each year, over 16 million new cancer cases are diagnosed globally. Cancer causes cells to grow uncontrollably, potentially leading to the formation of tumors, immune system damage, and other debilitating effects that can be fatal. Common cancer treatments include surgery to remove tumors, chemotherapy, radiation therapy, hormonal therapy, and immunotherapy. Among these, chemotherapy plays a significant role, accounting for nearly half of the overall treatment approach. Chemotherapy drugs can be …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 15–20 Read article
-
Need of Biocomposite Polymers In 3D Printing: Addressing Environmental and Public Health
Abstract: Concerns over the effects of conventional polymer materials on the environment and human health have been highlighted by the growing use of additive manufacturing or 3D printing. Traditional synthetic composites are usually made of petroleum-based plastics that include a range of chemical agents, such as additives and plasticizers. The increasing use of 3D printing has sparked concerns about the environmental and health risks linked to traditional polymer materials. With an …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 135–142 Read article
-
Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication
Abstract: Innate immunology represents the body's first line of defense against pathogens, acting as a rapid, non-specific response to a wide array of microbial invaders. This part of the immune system depends on pattern recognition receptors (PRRs) to identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), leading to the activation of immune cells such as macrophages, dendritic cells, and neutrophils. The innate immune system also plays a crucial role …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article