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1074 articles for “PHA”
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Synthesis, Characterization and Evaluation of Pyridine derivatives
Abstract: Schiff bases, a class of organic compounds, have garnered significant attention due to their diverse applications in various fields such as pharmaceuticals, materials science, and coordination chemistry. This study provides a comprehensive overview of the synthesis of Schiff bases amino pyridine derivatives and aromatic ketones along with their anti-microbial activity. Method: The synthesis of Schiff bases primarily involves the condensation reaction between a primary amine and a carbonyl compound (ketone) …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 35–48 Read article
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Blockchain Technology for Strengthening the Indian Generic Medicine Supply Chain and Combating Counterfeit Drugs
Abstract: India is one of the leading distributors of generic medicines globally, but its supply chain faces numerous challenges including substandard medicines, counterfeiting, and inefficient logistics. Blockchain technology offers a promising solution by providing a secure, decentralized, and transparent platform to track and verify the entire drug supply chain from production to delivery. This paper investigates the potential of blockchain to mitigate counterfeit drug circulation, improve trust in Indian generic medicines, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 9–12 Read article
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Sphagneticola trilobata: A Green Treasure of Phytochemical Constituents and Medicinal Values
Abstract: Sphagneticola trilobata originally from the Caribbean, Mexico, and Central America, and is a plant of the Asteraceae family, tribe Heliantheae, that is now found growing across the Neotropics. The plant profile, key components, chemical test, and pharmacological actions of S. trilobata are all included in this review. The main constituents of the plant were limonene, bicyclogermacrene, α-humulene, α-pinene, α-phellandrene, and germacrene D, camphene, sabinene, 10-nor-calamenen-10-one, γ-amorphene. Which shows pharmacological active …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 15–21 Read article
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Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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Exploring The Therapeutical Potential Of Pongamia Pinnata For Herpes Simplex Virus Type 1 (HSV-1)
Abstract: Objective: Pongamia pinnata (L.), commonly known as Indian beech or pongam tree, is a tropical plant renowned for its medicinal properties in traditional medicine systems. Extracts derived from various parts of Pongamia pinnata have demonstrated antimicrobial, anti-inflammatory, and immunomodulatory activities. Such attributes make it a compelling candidate for exploring its therapeutic potential against HSV infections. Thymidine kinase is the target protein mostly used in the treatment of HSV1 infections. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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A Value-Belief-Attitude Model of Local Food Consumption
Abstract: The paper explores the Value-Belief-Attitude (VBA) model of local food consumption, investigating how cultural, social, and economic factors influence attitudes toward local food. Key considerations include the importance of regional cuisines, support for local farmers, and the health benefits of fresh, locally sourced produce. The paper also delves into the concept of “locavorism” as a consumer ideology centered around the trustworthiness and benefits of local foods. Additionally, it examines long-term …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 1, 2025 · pp. 11–18 Read article
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Flaxseed-Based Drug Delivery Systems: Advancing Colon Cancer Treatment
Abstract: Flaxseed (Linum usitatissimum) has long been appreciated for its rich nutritional profile, including essential fatty acids (such as α-linolenic acid), plant fibers, and lignans. Recent research has focused on its potential as a novel drug delivery system (DDS) for the treatment of colon cancer. This review explores the bioactive constituents of flaxseed, their pharmacological activities, and innovative approaches to the use of flaxseed extracts in drug delivery for the treatment …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 54–59 Read article
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Formulation Development and Evaluation Technique for Immediate and Modified Release Capsule
Abstract: The development and evaluation of formulations for immediate-release (IR) and modified-release (MR) capsules represent a critical aspect of pharmaceutical dosage form design, offering distinct advantages in terms of drug release profiles and therapeutic outcomes. This study focuses on the formulation strategies, techniques, and evaluation methods used to develop both IR and MR capsules. Immediate-release capsules are designed to disintegrate quickly in the gastrointestinal tract, ensuring rapid drug absorption, while modified-release …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 1–9 Read article
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COSMECEUTICAL: The Intersection Between Beauty and Science
Abstract: The intersection of beauty and science has given rise to the rapidly growing field of cosmeceuticals—products that blend cosmetic and pharmaceutical elements to improve both the appearance and health of the skin. As consumers increasingly seek advanced, evidence-based skincare solutions, the demand for cosmeceuticals has surged. These products typically contain bioactive ingredients that go beyond simple aesthetic enhancement, offering therapeutic benefits backed by scientific research. The article explores the evolving …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 1, 2025 · pp. 17–31 Read article
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Utilizing Drones for Tracking Wild Life Conservation: Tracking Census and its Anti Poaching Efforts
Abstract: Remote-controlled conservation drones can gather data from hard-to-reach locations with the least amount of disruption. Drones are being employed more and more in various research fields, but there is still much to learn about how they might be applied to wildlife study. Remote-controlled conservation drones can gather data from hard-to-reach locations with the least amount of disruption. Drones are being employed more and more in various research fields, but there …
Published in International Journal on Drones · Vol. 1, Issue 1, 2025 · pp. 36–43 Read article
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Advances in Polymer Chemistry for Zinc Oxide Nanoparticle-Based Composites in Moisture Sensing Applications
Abstract: In present scenario the application of Polymer chemistry is various domain. It is used in sensing the moisture. This paper explores the synthesis and application of zinc oxide nanoparticles (ZnO-NP) deposited on polymer-based hygroscopic substrates to enhance the dielectric properties of capacitive sensors. The novel composite material, comprising ZnO-NP and cellulose-based substrates, offers superior moisture sensitivity, stability, and cost-effectiveness compared to conventional sensing materials. The synthesis process involves the controlled …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 79–85 Read article
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Advancements in Thermal Performance of Solar Flat Plate Collectors: A Comprehensive Review
Abstract: Over the past couple of years, solar flat plate collectors (FPSCs) have undergone significant improvement regarding their thermal performance. The review evaluates the improvement of materials such as advanced coatings; metals with a high thermal conductivity; and nanostructured additives. New cover technologies, such as polymeric films and anti-reflection coatings, are discussed, as well as novel insulation technologies such as aerogels and vacuum panels. Also of interest are phase-change materials and …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 2, 2025 · pp. 10–14 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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Pediatric and Geriatric Formulation Tailoring Dosage Form for Age-Specific Needs
Abstract: This comprehensive review addresses the critical challenges and advancements in the formulation of oral medications for pediatric and geriatric populations, who often face unique pharmacokinetic and pharmacodynamic differences. The World Health Organization highlights that nearly 50% of long-term medications are not adhered to, with significant implications for health outcomes. Pediatric patients, due to their developmental stages, and geriatric patients, due to age-related physiological changes, require tailored drug formulations to enhance …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 89–103 Read article
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Polymer Chemistry-Driven Approaches for Improved Therapeutic Delivery
Abstract: Polymer chemistry has revolutionized pharmaceutical technology by enabling the development of advanced drug delivery systems with improved precision, stability, and therapeutic outcomes. This review explores the role of polymer design, synthesis, and functionalization in the development of responsive and targeted drug carriers. Emphasis is placed on various types of polymers—biodegradable, synthetic, natural, and stimuli-responsive—and their suitability for drug delivery platforms such as nanoparticles, micelles, hydrogels, dendrimers, and implants. The physicochemical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 Read article
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A study on Public Perception and self-medication practices with Over-the-counter (OTC) Drugs
Abstract: Over-the-counter (OTC) medications are commonly used by individuals for self-medication due to their easy availability and the general belief that they are safe. However, misuse can lead to negative health outcomes such as adverse reactions, drug interactions, and delays in seeking professional medical care. In a country like India, where enforcement of drug regulations can vary and socioeconomic factors play a major role, the practice of self-medication is especially widespread. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 01–07 Read article
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Understanding the Cervical Spine Disorder: A Cross-sectional Survey Study
Abstract: Cervical spine disorders encompass a spectrum of conditions including degenerative spondylosis, disc herniation, traumatic injuries, and myelopathy that impair quality of life through chronic pain, neurological deficits, and functional limitations. Globally, neck pain affects over 200 million individuals, with an age-standardized prevalence of 2666 per 100000 population and an incidence of 816 per 100000 person-years, contributing to significant years lived with disability (YLDs). Economic analyses estimate annual direct healthcare costs …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 80–97 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Post Halela Zard (Terminalia chebula Retz.): A Review on Medicinal Utility from the Perspective of Unani Medicine
Abstract: Halela Zard (Terminalia chebula Retz.), commonly known as Haritaki in Sanskrit and Chebulic Myrobalan in English, is a cornerstone of Unani pharmacotherapy due to its remarkable therapeutic versatility. The dried pericarp of its fruit has been extensively employed in traditional medicine for the treatment of a wide spectrum of ailments, ranging from digestive disturbances to chronic systemic disorders. This review aims to present a comprehensive overview of Halela Zard by …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 19–26 Read article