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474 articles for “Clinical study”
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Muscle vs. Heart: A Comprehensive Review of Anabolic Steroid-Induced Cardiovascular Risks
Abstract: Anabolic-androgenic steroids (AAS) are widely used by athletes and bodybuilders to enhance muscle mass and performance. However, their misuse is associated with serious and often underrecognized cardiovascular risks. Despite their popularity, particularly among young adults, the long-term consequences of AAS abuse on cardiovascular health remain insufficiently explored in the literature. This review aims to: 1. Analyze the cardiovascular implications of AAS use. 2. Elucidate the molecular and physiological mechanisms contributing …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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Study Review: Molecular Mechanisms of Nanoparticle-Cell Interaction – Implications for Drug Delivery and Toxicity
Abstract: The application of nanoparticles in drug delivery and biomedical therapies holds great promise, yet their interaction with cells and the underlying molecular mechanisms remains areas of active research. This study explores the molecular mechanisms of nanoparticle-cell interactions, focusing on the effects of gold nanoparticles (AuNPs) and silica nanoparticles (SiNPs) in human cancer cell lines (HeLa and MCF-7). The study examines how nanoparticles are internalized by cells, their impact on cellular …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 31–40 Read article
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Multiple Sclerosis: A Brief Overview of the Disease, Its Pharmacotherapy
Abstract: Multiple Sclerosis is an autoimmune disorder mostly affecting individuals aged between 20-40. In this disorder, the optic, vertebral, and central nervous system nerves are primarily impacted. It is a neurological condition that worsens over time and is characterized by inflammation and the breakdown of the sheath that surrounds and shields the nerve fiber. Common symptoms may include muscle weakness, numbness, tingling, fatigue, vertigo, tremor, vision complications, pain, Lhermitte sign, sexual …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Associations of C-RP with Renal Function Group and some Clinical Parameters in Patients with Dialysis in Iraq
Abstract: Introduction: Chronic kidney disease is a disease for which there are high mortality rates among those infected with many complications, including high rates of inflammation, anaemia, osteoporosis, and other complications. Methods: The current study was designed to evaluate the kidney functions of patients undergoing dialysis, where levels were evaluated Urea, Uric Acid, and Creatinine, in addition to C-Reactive Protein as a progressive of inflammation parameter, and to evaluate anaemia levels …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 4, Issue 1, 2026 Read article
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A Community-Based Study to Assess: The Aggravating Factors and Treatment Choices in Youth with Acne
Abstract: Background and Aim: Acne vulgaris is a common dermatological condition affecting youth worldwide. While its pathogenesis is well-understood, individual experiences with aggravating factors and treatment choices vary. This study aimed to evaluate self-reported factors aggravating acne and determine treatment choices among youth with acne while assessing the correlation between self-perceived and clinically assessed acne severity. Methodology: A cross-sectional survey was conducted with 390 participants aged 18–24 suffering from acne. Data …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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The Role of Polymer Chemistry in Developing a Novel Polymer-Based Retromolar Endotracheal Tube
Abstract: This study presents the development and characterization of a novel polymer-based modified endotracheal tube designed for retromolar intubation. The tube is manufactured using medical-grade polyvinyl chloride (PVC) with reinforced polymeric structures to enhance flexibility while maintaining lumen integrity. The incorporation of a preformed lateral curvature mitigates airway resistance and airflow reduction caused by manual bending, ensuring an optimal balance between rigidity and adaptability. Additionally, the integration of polymer-based ligature wires …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 14–20 Read article
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Drug Screening Using Stem Cell Technology
Abstract: Stem cell technology in drug screening has transformed the research and development sector of pharmaceuticals. Although stem cells imitate their human counterparts in terms of both safety and potential, it is a new paradigm for mimicking diseases of humans and scale measuring for toxicity. These tissues will, therefore, be more predictive of what will happen in humans during clinical situations, compared to conventional cell lines or animal models, since they …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 42–51 Read article
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A Comprehensive Review of Forensic Medicine: Its Evolution, Scope, Applications, and Future Directions
Abstract: Forensic medicine, a key junction of medical and law, has evolved substantially throughout the centuries, responding to scientific and technological advances. Forensic medicine, derived from the Latin term forensis, meaning “before the forum,” has evolved significantly over the centuries from rudimentary methods of determining the cause of death to a sophisticated and highly specialized medical discipline. Today, it encompasses a wide range of fields, including clinical forensic medicine, forensic pathology, …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 18–28 Read article
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U-Net Based Approach for Automated Brain Tumor Classification
Abstract: Brain tumor detection and identification play vital roles in diagnostic procedures in the field of medicine, with the conventional analysis of MRI images requiring a lot of time and also subject to variability. The proposed study involves the use of a CNN-U-Net based approach for brain tumor detection and identification automatically. The study uses a database of 3,064 contrast-enhanced T1-weighted MRI images from 233 patients with the tumors of meningioma, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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A Hybrid Machine Learning Approach for Cardiovascular Disease Prediction
Abstract: Heart disease ranks among the top causes of death globally. Accurately predicting cardiovascular conditions has become a key challenge in the realm of clinical data analysis. It has been shown that machine learning is an effective means of assisting with predicting and decision-making based on the large volume of data produced by the medical industry. In this study, we describe a unique approach that increases the prediction accuracy of heart-related …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 1, 2025 · pp. 69–75 Read article
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Exploring the Development of AI Models Using Open-Source Tools to Predict Patient Outcomes and Optimize Treatment Plans
Abstract: Integrating artificial intelligence (AI) into healthcare offers a transformative opportunity to enhance patient care and clinical decision-making. Through the use of predictive analytics, AI can significantly enhance the accuracy of outcome predictions and assist in developing personalized treatment plans that cater to each patient’s specific needs. This paper delves into the development of AI models using open-source tools, which are increasingly favored for their accessibility, collaborative nature, and capacity for …
Published in Journal of Open Source Developments · Vol. 11, Issue 3, 2024 · pp. 37–49 Read article
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A Comparative Study of Deep Learning Methods for Depression Detection in Social Media Data
Abstract: With the rise of social media platforms like Twitter, Reddit, and Facebook, individuals increasingly share personal information about their moods, behaviors, and mental states. This trend provides a unique opportunity to leverage large-scale textual data for understanding and monitoring mental health conditions, particularly depression, a prevalent and challenging mental health issue. Traditional depression assessments are often confined to clinical environments and lack the capacity for real-time monitoring. In contrast, social …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 3, 2025 · pp. 55–65 Read article
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AI Approaches in Gait and Posture Analysis: A Review
Abstract: This review synthesizes current research on the application of artificial intelligence (AI) in gait and posture analysis, focusing on methodologies, algorithms, and clinical applications. It examines the use of machine learning (ML) and deep learning (DL) techniques to extract relevant features from sensorderived data, offering objective, and automated assessments that surpass traditional methods. A systematic literature review was conducted, analyzing studies that utilized AI for gait and posture analysis with …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 1–3 Read article
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Host-Pathogen Coevolution: Implications for Immune Evasion and Pathogen Fitness
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 · pp. 6–10 Read article
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How Scientists Look for New Pathogens Before They Spread
Abstract: Emerging infectious illnesses are a persistent danger to global health. They often come from unexpected places, such wildlife reservoirs, changes in the climate, or human activities. Finding new diseases before they create epidemics is one of the biggest problems in modern epidemiology. This article talks about how scientists use genetic monitoring, field sampling, and real-time data processing to find, track, and describe new infectious organisms in a way that works …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 11–17 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 Read article
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A Study to Evaluate the Effectiveness of Planned Teaching Program on Diabetic Management Regarding Knowledge and Practice Among Patients with Diabetes Mellitus at Selected Taluk Government Hospital, Kollegala
Abstract: Diabetes mellitus is a chronic metabolic disorder with a growing global impact. Effective management of this condition requires not only medical intervention but also comprehensive patient education. This study was conducted to evaluate the effectiveness of different diabetes education methods on improving metabolic control, body mass index (BMI), and blood pressure among diabetic patients. The research aimed to empower individuals with diabetes by enhancing their knowledge and self-management skills. A …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 3, 2025 · pp. 19–28 Read article
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Shaping Views: Nursing Students’ Perception Towards the Profession
Abstract: Nurses play a vital role in the healthcare system, providing essential care across diverse populations. As the backbone of health services in the 21st century, the nursing profession demands skilled practitioners who contribute significantly to patient care, health promotion, and disease prevention. However, global shortages of nursing professionals, particularly in countries like India, threaten healthcare quality and accessibility. Understanding nursing students’ perceptions of their profession is crucial, as these views …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 3, 2025 · pp. 1–10 Read article
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Risk & Opportunities in Development of new Drugs: A New Perspective
Abstract: The procedures of drug discovery and development are briefly described in this article. Our goal is to assist researchers whose work may be pertinent to the discovery and/or development of new drugs in framing their research reports in a way that appropriately situates their findings within the drug discovery and development process and supports the efficient translation of preclinical research to humans. One overarching theme of our article is the …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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Early Disease Detection Using Artificial Intelligence
Abstract: Growth in artificial intelligence and machine learning now make it possible for the healthcare sector to be totally transformed by a new chapter, particularly in the era of medical image analysis. This study focuses on harnessing these advancements to develop a sophisticated model for early disease detection across diverse medical domains, majorly in skin disease. By integrating diverse datasets and leveraging advanced algorithms, our methodology aims to identify subtle disease …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 3, 2024 · pp. 11–19 Read article