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384 articles for “bi-directional”
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Swift Solutions: The Science and Innovation Behind Fast-Dissolving Tablets
Abstract: Swift solutions in the context of fast dissolving tablets (FDTs) represent an innovative breakthrough in pharmaceutical science, aiming to provide rapid and effective drug delivery for patients who face difficulty swallowing conventional dosage forms. The science and innovation behind FDTs are rooted in advanced formulation techniques, material science, and drug delivery mechanisms that prioritize speed, convenience, and patient compliance. These tablets are formulated to dissolve quickly in the mouth, removing …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 26–36 Read article
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Alcohol, Circadian Glymphatic Dysfunction, and Neurodegenerative Protein Accumulation: An Emerging Concern in the Indian Context
Abstract: Alcohol consumption has long been identified as a major public health issue, yet its deeper and more subtle effects on the human brain are only now coming into sharper focus. Traditional explanations often emphasize direct neuronal damage, but emerging research in neuroscience suggests a more intricate story. Recent findings indicate that alcohol not only harms brain cells but also disrupts the body’s internal biological clock—the circadian rhythm—which plays a critical …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 1–4 Read article
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Lysogenic Phage Cocktails with Embedded Fluorophores for Field Wound Diagnostics.
Abstract: Rapid and accurate detection of wound infections in field settings remains a critical challenge in emergency and military medicine. Conventional microbiological diagnostics are time- consuming and laboratory-dependent. Bacteriophages, particularly lysogenic phages, offer high specificity toward bacterial hosts and can be engineered as diagnostic tools. A translational framework was developed for lysogenic bacteriophage cocktails embedded with fluorophore reporters for rapid, point-of-care wound diagnostics. Mechanisms of phage infection, lysogenic integration, and fluorophore …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 Read article
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Advancements and Future Directions in Polymers for Electric Vehicle Technology
Abstract: Plastics have become important internally in automotive applications, ranging from vehicle inner components to under the hood of the car, as they are flexible and help on improving fuel economy and reducing CO2 emissions by replacing metal. The last two years had seen a higher rate of electric car sales even though its adoption around the world was not at the same pace. There is still a doubt among the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 29–46 Read article
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Molecular Docking studies of Benzodiazepine Derivatives With GABA(B) Receptor
Abstract: Benzodiazepines (BZDs) are pharmacologically significant compounds that act by binding to GABA A neurotransmitter receptors, subsequently augmenting GABA-induced chloride ion flux, consequently inducing neuronal hyperpolarization. Benzodiazepines are commonly used in the treatment of sleep disorders, anxiety, muscle spasms, seizure disorders, and some forms of depression. The primary inhibitory neurotransmitter, GABA, functions on two types of receptors: the ligand-gated GABA A/C receptors and the G protein-coupled GABA B receptors. These neurotransmitters …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 1–14 Read article
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Flaxseed-Based Drug Delivery Systems: Advancing Colon Cancer Treatment
Abstract: Flaxseed (Linum usitatissimum) has long been appreciated for its rich nutritional profile, including essential fatty acids (such as α-linolenic acid), plant fibers, and lignans. Recent research has focused on its potential as a novel drug delivery system (DDS) for the treatment of colon cancer. This review explores the bioactive constituents of flaxseed, their pharmacological activities, and innovative approaches to the use of flaxseed extracts in drug delivery for the treatment …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 54–59 Read article
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Multifunctional Car Covering System
Abstract: Traditional car covers are heavy, consume much space, and are not suitable for today’s advanced generation. They fail to meet the evolving necessities of modern vehicle protection. Often, they are operated manually, offer minimal security, and lack advanced features such as automated deployment or integrated maintenance systems. To address these problems and limitations, this project introduces an innovative and multifunctional smart car covering system powered by a wiper-like mechanism and …
Published in Journal of Automobile Engineering and Applications · Vol. 13, Issue 2, 2026 Read article
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Optimizing Power Generation from Building Ventilation Systems: A Study on Exhaust Fan Efficiency
Abstract: Due to population growth, the world's energy consumption has increased dramatically in both wealthy and developing nations in recent years, and by 2042, it is predicted to have doubled or more. Since a few years ago, the use of innovative sustainable power sources to meet energy demands has been gradually increasing. We've chipped away at a different idea because of this. As an alternative energy source, renewable energy (RE) resources …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 2, 2023 · pp. 22–27 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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Understanding the Intersectional Challenges of LGBTQ community in the Indian Society: A Systematic Review Paper
Abstract: This study examines the intersectional issues that the LGBTQ population faces in Indian society, examining how their lived experiences are shaped by caste, class, religion, and regional differences. The purpose of this study is to investigate how the experiences of LGBTQ people in India are impacted by several axes of identification, including caste-based discrimination, economic position, geographical inequities, and religious biases. 43 research papers have been reviewed from which 30 …
Published in Recent Trends in Social Studies · Vol. 2, Issue 2, 2025 · pp. 22–30 Read article
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A Survey of Role-Based Access Control Implementation in HMI Systems for Industrial Automation
Abstract: The convergence of Role-Based Access Control (RBAC) and Human-Machine Interface (HMI) systems presents a transformative approach to secure and efficient industrial automation in Industry 4.0. By integrating RBAC with Multi-Factor Authentication (MFA), this framework enhances cybersecurity while maintaining operational flexibility, mitigating both external threats and internal vulnerabilities. Modern adaptive HMIs further optimize user experience through personalized and intuitive interfaces, though challenges remain in balancing functionality with simplicity in complex industrial …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 10–19 Read article
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Automated Blood Cell Counting and Disease Identification Using Image Processing: Implications for Polymer Composite- Based Biomedical Diagnostic Devices
Abstract: Accurate quantification of blood cells is central to clinical decision-making and to the performance of emerging polymer composite–based diagnostic platforms. This work presents a cost-effective, image-processing pipeline for automated counting of red blood cells (including overlapping cells), white blood cells, and platelets from Leishman-stained peripheral blood smears, and articulates its relevance to polymer composite microfluidic and biosensor devices. Implemented in Python with OpenCV, the workflow performs grayscale conversion, median/Gaussian denoising, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 262–270 Read article
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Quantum-Fuzzy Tensor Operators and Uncertainty-Band Bifurcation for Symmetry-Preserving State Discrimination
Abstract: A tensor-operator framework is developed for fuzzy conjunction, fuzzy disjunction, and symmetry-preserving state discrimination in multi-qubit quantum systems. In this formulation, fuzzy membership and non-membership degrees are represented through expectations of effect operators acting on density matrices, providing a natural bridge between fuzzy logic and quantum measurement theory. Conjunction and disjunction operations are extended to the quantum domain via tensorised channels, constructed using projective measurements and unitary transformations, enabling logical …
Published in Emerging Trends in Symmetry · Vol. 2, Issue 1, 2026 · pp. 08–15 Read article
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Deciphering the Roles of Estrogen Receptors and 27-Hydroxycholesterol in BC Progression
Abstract: Breast cancer (BC) ranks among the top causes of cancer-related deaths in women worldwide. Many risk factors of BC are linked to estrogen. Experiments of Beatson in 1896 show the role of steroid hormones as major determinant in BC. Action of steroid hormones is mediated by their receptors including Estrogen receptors (ERs). ERs are part of a subfamily of ligand-regulated transcription factors. Their primary role is to translate hormone signals …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 18–26 Read article
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Designing Aspects and Recent Advances in Digital Holographic Microscopy
Abstract: Recent advances in Digital Holographic Microscopy have been discussed in this paper, besides throwing some light on the designing aspects of optical components like beam splitter and neutral density filter for the optimization of system performance. Some important related subtopics like spectral resolution of digital holograms, and Fourier-synthesis holography have been technically discussed. The optimization of acoustical holographic components for use in renewable energy production is presented in this study. …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 2, 2025 · pp. 06–18 Read article
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Design and Implementation of a 4-Bit Breadboard CPU Using Digital Integrated Circuits
Abstract: This paper presents the design and hardware realization of a simple 4-bit CPU built using discrete TTL integrated circuits on a breadboard. The CPU employs a 4-bit common data bus with tri-state buffers for device arbitration, three 4-bit registers (Register A, Register B, and an Output Register) implemented with 74LS175 quad D flip-flops, and a 4-bit ALU for addition/subtraction using a 74LS83 adder and XOR gates. Manual control signals (load, …
Published in Journal of Electronic Design Technology · Vol. 17, Issue 2, 2026 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Advanced Controlled Drug Delivery Systems
Abstract: Polymer-gel forms have gained popularity in medicine as means of medication delivery over the skin. This is so since they enable medications pass the skin more readily. These products allow medicine to be administered without surgery and provide continuous active ingredient supply. They are excellent for long-term therapy for managing conditions that keep resurfacing. From tiny synthetic ones to huge biological ones, polymer gels can store a wide spectrum of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 271–284 Read article
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Polymer Chemistry-Guided Development of Biomimetic Composite Scaffolds
Abstract: Polymer chemistry plays a fundamental role in advancing biomaterials for anatomical tissue engineering, particularly in the design of composite scaffolds that replicate the intrinsic characteristics of native tissues. The regeneration of damaged tissues, especially within anatomically complex structures such as bone, cartilage, and skin, necessitates biomaterials that closely emulate the hierarchical architecture and biological functions of native extracellular matrices (ECMs). The capacity to replicate both mechanical and biochemical cues of …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 7–13 Read article
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Comparative Study of Structural and Optical Properties of Bismuth Ferrite Nanoparticles for Photovoltaic Applications Synthesized via Different Sol-Gel Methods
Abstract: Pure multiferroic bismuth ferrite (BiFeO3) nanoparticles were successfully synthesized using an energy-efficient, low-temperature sol-gel method, comparing two distinct approaches: auto-combustion and non-auto-combustion. To ensure phase stability, the precursor solution's pH was strictly maintained between 1 and 2 using ammonia solution (NH4OH), while ethylene glycol (C2H6O2) was employed as a chelating agent for the Fe3+ and Bi3+ cations. All samples underwent a final annealing process at 500 °C to promote crystallization. …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 1, 2026 · pp. 83–94 Read article
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Integration of Taguchi and MCDM Techniques for the Optimization of Experimental Parameters in Electrical Discharge Machining: A Research
Abstract: Electric discharge machining (EDM) represents a non-conventional approach to machining, particularly beneficial for processing hard-to-machine materials or components with high length-to-diameter ratios or intricate shapes. Widely employed across various industries such as automotive, chemical, aerospace, biomedical, and tool and die, EDM offers a unique method for achieving precise shapes and dimensions. Unlike traditional machining methods where form is attained through the interaction of the tool and workpiece, EDM operates without …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 6–14 Read article