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216 articles for “Physiology”
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Investigating mosquito innate immune defence mechanism towards malaria vaccine development
Abstract: Mosquito-borne diseases weigh heavily on public health across the globe. The mosquito’s innate immune system certainly decides whether malaria parasites survive inside the vector, and that sighted it as a logical place to discover new vaccine ideas. In this review, we examine how Anopheles mosquitoes defend themselves against Plasmodium parasites and how those defenses could be turned into tools for malaria control. We focus on three layers of immunity: antimicrobial …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 50–54 Read article
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Pharmacokinetics of Levothyroxine and Factors Influencing Its Therapeutic Efficacy in Hypothyroidism: A Comprehensive Review
Abstract: Levothyroxine (LT4) remains the standard therapy for hypothyroidism due to its effectiveness in restoring normal thyroid hormone levels and improving physiological functions. However, its pharmacokinetic profile exhibits considerable variability, which may influence therapeutic outcomes in clinical practice. This review aims to comprehensively evaluate the pharmacokinetics of levothyroxine, including its absorption, distribution, metabolism, and elimination, along with factors affecting its therapeutic efficacy. A structured literature search was conducted using electronic databases, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 Read article
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Recombinant Proteins and Nested Gene Regulation: Nutrient Driven Immune Response and Disease Resistance in Livestock
Abstract: Livestock production systems are increasingly challenged by infectious diseases, metabolic disorders, and environmental stressors that reduce productivity and compromise animal health. Advances in molecular biology and animal nutrition now offer new opportunities to strengthen disease resistance through integrated strategies that combine recombinant protein technologies, gene regulatory mechanisms, and nutrient mediated immune modulation. This review examines how recombinant proteins and nested gene regulation interact to shape nutrient driven immune responses in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Design and Evaluation of Thermo-Responsive Poly(N-isopropylacrylamide)-Based Polymeric Nanoparticles for Temperature-Triggered Intratumoral Release of Doxorubicin in Solid Tumors
Abstract: Thermo-responsive polymeric systems have emerged as promising platforms for targeted intratumoral drug delivery in cancer therapy. This study aimed to develop and evaluate poly(N-isopropylacrylamide) (PNIPAM)-based polymeric nanoparticles as intelligent carriers for temperature-responsive delivery of doxorubicin (DOX) to solid tumors. Nanoparticles were synthesized via free radical polymerization using N-isopropylacrylamide as a thermoresponsive monomer and N,N′-methylenebisacrylamide as a crosslinker, forming a stable network with a tunable lower critical solution temperature (LCST).The optimized …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 159–168 Read article
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Effectiveness of a Structured Educational Intervention on Managing Minor Disorders of Pregnancy Through Home Remedies Among Antenatal Women in Urban and Rural Kuppam
Abstract: Pregnancy is a physiological process often accompanied by minor disorders such as nausea, vomiting, backache, heartburn, and fatigue, which can affect the well-being of expectant mothers. Appropriate knowledge and timely management using simple home remedies can significantly reduce discomfort and improve maternal health. This study aimed to evaluate the effectiveness of a structured educational intervention on the management of minor disorders of pregnancy through home remedies among antenatal women in …
Published in International Journal of Midwifery Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 7–15 Read article
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Phosphorescence of Carbon Nanodots – The Phenomena and the Applications
Abstract: Photoluminescence has emerged as a fundamental phenomenon in modern biomedical science, enabling advanced diagnostic, therapeutic, and theranostic applications through light–matter interactions at the nanoscale. The ability of photoluminescent materials to absorb electromagnetic radiation and emit light at distinct wavelengths has been widely exploited in bioimaging, biosensing, drug delivery tracking, and photodynamic therapy. Among various photoluminescent nanomaterials, carbon nanodots have attracted significant attention due to their strong emission intensity, tunable fluorescence, …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 01–05 Read article
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Muscle vs. Heart: A Comprehensive Review of Anabolic Steroid-Induced Cardiovascular Risks
Abstract: Anabolic-androgenic steroids (AAS) are widely used by athletes and bodybuilders to enhance muscle mass and performance. However, their misuse is associated with serious and often underrecognized cardiovascular risks. Despite their popularity, particularly among young adults, the long-term consequences of AAS abuse on cardiovascular health remain insufficiently explored in the literature. This review aims to: 1. Analyze the cardiovascular implications of AAS use. 2. Elucidate the molecular and physiological mechanisms contributing …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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A Conceptual Framework for AI-Integrated Metabolomics in Predictive Health Systems for Resource-Constrained Environments
Abstract: The increasing prevalence of non-communicable diseases (NCDs) continues to place a significant strain on healthcare systems, particularly in low- and middle-income regions where access to early diagnostic infrastructure is limited. Conventional healthcare approaches remain largely reactive, often detecting diseases at advanced stages when treatment effectiveness is reduced. This challenge underscores the need for predictive, cost-effective, and data-driven healthcare solutions. This study presents a conceptual framework that integrates metabolomics with artificial …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 2, 2026 Read article
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Role of Impaired Digestion in Disease Pathogenesis: According to Unani System of Medicine
Abstract: The relationship between digestion and disease occupies a central position in Greco-Arab (Unani) medicine, as emphasized by classical physicians such as Ibn Sina and Al-Razi. In Unani medicine, digestion (Haḍm) is not confined to the gastrointestinal tract alone but represents a comprehensive physiological and metabolic process involving four sequential stages: gastric digestion (Haḍm-e-Mi‘dī), hepatic digestion (Haḍm-e-Kabidī), vascular digestion (Haḍm-e-‘Urūqī), and tissue digestion (Haḍm-e-‘Uḍwī). These stages are governed by Quwwat-e-Hāḍima (digestive …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 Read article
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Gastro Retentive Drug Target System: Its Needs, Advantages, Limitation and Approaches
Abstract: Background: Gastro retentive drug delivery systems (GRDDS) address limitations of oral therapy for drugs with poor solubility, instability at intestinal pH, or narrow absorption windows by prolonging gastric residence and increasing contact with the gastric mucosa. Objectives: To review GRDDS approaches—floating systems, mucoadhesive systems, and super porous hydrogels—with emphasis on formulation strategies and polymer–excipient selection to enhance gastric retention, modulate buoyancy/swelling/adhesion, and ultimately improve oral bioavailability and therapeutic outcomes for …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Dystocia in Dairy Cattle: Causes, Consequences, and Preventive Measures for Improved Reproductive Health and Productivity
Abstract: Dystocia, or calving difficulty, is a significant reproductive challenge in dairy cattle, with far-reaching impacts on animal health, productivity, and farm economics. This review paper comprehensively explores the primary causes, consequences, and effective preventive measures associated with dystocia in dairy cows. Dystocia arises from a complex interplay of genetic, physiological, environmental, and management-related factors, including breed predisposition, maternal and fetal size, pelvic structure, and gestational nutrition. The consequences of dystocia …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 15, Issue 2, 2026 Read article
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Legume-Induced Frothy Bloat in Tropical Cattle: Pathophysiology, Consequences and Preventative Measures
Abstract: Legume-induced bloat in tropical cattle is a complex and significant health challenge that affects livestock productivity and welfare. This review aims to elucidate the multifaceted causes of bloat associated with the consumption of leguminous forages, highlighting both the physiological mechanisms and environmental factors that contribute to this condition. Key factors include the high soluble protein content of legumes, rapid fermentation rates in the rumen, and the formation of stable foam, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 Read article
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Sources and Health Effects of Arsenic, Fluoride, and Nitrate in Water
Abstract: Arsenic, fluoride, and nitrate are major inorganic contaminants in water that pose significant risks to human health. These contaminants are introduced into water sources through both natural geological processes and human activities. Arsenic is primarily released from arsenic-bearing minerals through weathering, dissolution, and erosion, while human activities such as agriculture, mining, and fossil fuel combustion further enhance its presence in water. Fluoride contamination mainly results from the dissolution of fluoride-bearing …
Published in Journal of Water Resource Engineering and Management · Vol. 13, Issue 2, 2026 · pp. 19–25 Read article
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Nutraceuticals & their classification: A Review
Abstract: The combination of "nutrition" and "pharmaceutical" is called nutraceutical. Nutraceuticals, in general, are foods or dietary components that significantly contribute to changing and preserving normal physiological function, which keeps people healthy. Nutraceuticals can be classified into various categories on the basis of their composition and mechanism of action. Nutraceuticals are food items that contain dietary fibre (DF), probiotics, prebiotics, polyunsaturated fatty acids (PUFA), antioxidants, and other herbal natural foods. These …
Published in International Journal of Land · Vol. 1, Issue 1, 2024 · pp. 11–17 Read article
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Photosynthetic Living Plant–Integrated Cybernetic Sensors for Autonomous Environmental Intelligence
Abstract: The increasing demand for sustainable and autonomous environmental monitoring systems has motivated the development of biologically integrated sensing technologies that combine living organisms with advanced cybernetic intelligence. This study proposes a novel framework of Photosynthetic Living Plant–Integrated Cybernetic Sensors for Autonomous Environmental Intelligence, where living plants act as self-sustaining sensing platforms capable of continuously monitoring environmental conditions without external energy sources. By integrating bioelectrical signal acquisition modules, flexible nanomaterial electrodes, …
Published in Recent Trends in Sensor Research & Technology · Vol. 13, Issue 2, 2026 Read article
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The Role of Artificial Intelligence in Enhancing Athlete Performance and Training Strategies
Abstract: Artificial Intelligence (AI) is transforming modern sports by improving athlete performance, training methods, and decision-making processes. The integration of AI technologies such as machine learning, data analytics, wearable sensors, and computer vision has enabled coaches and sports scientists to analyze large amounts of performance data with greater accuracy and efficiency. Athletes' physiological indicators, movement patterns, injury risks, and recuperation processes are all monitored by these technology. Training regimens can therefore …
Published in Recent Trends in Sports · Vol. 3, Issue 2, 2026 · pp. 1–7 Read article