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288 articles for “Genetics”
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Extended-spectrum beta-lactamases (ESBLs) and Metallo-beta-lactamases (MBLs): A Review
Abstract: Gram-negative bacteria produce extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs), enzymes that play a crucial role in antibiotic resistance. These enzymes enable the bacteria to withstand a wide array of beta-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. The production of these enzymes, particularly by organisms, such as Escherichia coli and Klebsiella pneumoniae, complicates treatment options for severe infections, leading to increased morbidity and mortality in clinical settings. ESBLs are primarily responsible …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 8–19 Read article
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Land Use and Land Cover Change: A Comprehensive Review of Environmental Implications
Abstract: Changes in land use and cover have a substantial impact on environmental dynamics and sustainability. These changes arise from various human activities, including urbanization, agriculture, and forestry, and have profound implications for biodiversity, ecosystem services, and land health. As urban areas expand, often at the expense of agricultural and forested landscapes, the transformation of land use alters ecological processes, leading to habitat loss and fragmentation. This article examines the implications …
Published in International Journal of Land · Vol. 1, Issue 2, 2024 · pp. 01–05 Read article
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Pathogens in Nosocomial Infections: Epidemiology, Resistance, and Control Measures
Abstract: Nosocomial infections, also known as healthcare-associated infections (HAIs), are a serious global health issue, leading to higher patient morbidity, prolonged hospital stays, and increased medical costs. Various pathogens—such as bacteria, viruses, fungi, and parasites—are responsible for these infections, especially in healthcare environments where they easily spread. They can be transmitted through direct contact with infected patients, contaminated medical equipment, or even airborne particles.Patients with weakened immune systems, those requiring prolonged …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 12–16 Read article
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Future Prospects of AI in Pharmaceutical Industry and its Limitation
Abstract: The pharmaceutical industry is facing significant challenges, including prolonged drug development timelines, high costs, and low success rates in clinical trials. Traditional methods often result in inefficiencies, with new drug development taking over a decade and billions of dollars, yet most candidates fail in clinical trials due to issues like inefficacy or safety concerns. Artificial Intelligence (AI) has become a groundbreaking technology with the potential to tackle these issues effectively. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 6–13 Read article
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A Comprehensive Review of Literature on Endometriosis: Pathophysiology, Diagnosis, and Management
Abstract: The endometrium, a tissue that resembles the lining of the uterus, develops outside the uterus in endometriosis, a chronic and frequently painful illness. Other parts of the body may also be affected, however the ovaries, fallopian tubes, and the tissue lining the pelvis are the most frequently affected. Infertility, heavy menstrual flow, and pelvic pain are the main signs of endometriosis, though each person may experience these symptoms to varying …
Published in International Journal of Midwifery Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 1–5 Read article
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Personalized Medicines in Pharmaceutics: Drug Delivery System
Abstract: Pharmaceutics personalized medicine is a developing area that seeks to customize medical interventions for specific patients. Instead of a one-size-fits-all approach, personalized medicine focuses on developing treatments that consider a person’s unique characteristics, such as their genetic makeup, environment, and lifestyle. This allows for more effective treatment outcomes, as drugs are specifically designed to work best for each patient, reducing side effects and improving therapeutic results. In pharmaceutics, this involves …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
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Understanding Metabolic Syndrome and its Nutritional Management
Abstract: Metabolic syndrome (MetS) is a collection of risk factors, especially when at least three occur together, including abdominal obesity, dyslipidemia, low high-density lipoprotein cholesterol (HDL-c) levels, hypertension, and insulin resistance. MetS is linked to an increased risk of diabetes and cardiovascular diseases (CVDs) if treatment is not received.The causes of MetS include both genetic and acquired factors that contribute to issues such as insulin resistance, chronic low-grade inflammation, and obesity. …
Published in International Journal of Sustainability · Vol. 2, Issue 1, 2025 · pp. 26–37 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article
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Evolutionary History of Endemic Species of Bihar
Abstract: Bihar, a state known for its history and rich cultural heritage, is also a refuge of clearly defined species that are unique to the world and are found no place else. The present study involving the history of these species by using genetic analysis, fossil evidence, and ecological studies, investigates the situation. Through initial and secondary explanation, we can realistically infer some of them locked in so closely with their …
Published in Research & Reviews : Journal of Ecology · Vol. 14, Issue 2, 2025 · pp. 1–10 Read article
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Harnessing Microalgae for Wastewater Treatment: Industrial Prospects and Environmental Benefits
Abstract: Simultaneous pollutant removal and biomass valorization has made microalgae an attractive and innovative solution to wastewater treatment, which could be considered a sustainable, low cost, and low energy approach. Considering their ability to store carbon dioxide, resorb nutrients, and produce valuable bioproducts, they represent an alternative with ecological potential to other previously used treatment methods. This review discusses how microalgae are used in industrial applications including biofuels, pharmaceutical, cosmetic, agriculture, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Implementing Machine Learning in Data Classification
Abstract: Data classification forms an essential aspect of artificial intelligence (AI) and soft computing, helping a great deal in the transformation of raw data into knowledge that forms the basis of numerous applications, such as fraud detection, medical diagnostics, and natural language processing. This study discusses the challenges and the state of the art in data classification, as far as scalability, noise handling, and feature selection optimization are concerned. It gives …
Published in International Journal of Data Structure Studies · Vol. 3, Issue 2, 2025 · pp. 15–22 Read article
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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Livestock and Rural Livelihoods: Nutritional, Economic, and Environmental Pathways to Sustainable Development
Abstract: Livestock play a pivotal role in sustaining rural livelihoods by contributing to economic stability, social empowerment, and environmental resilience. This study explores the diverse functions of livestock in rural communities, focusing on their contributions to income generation, food security, nutrient cycling, and cultural practices. Livestock provide essential goods such as milk, meat, eggs, and fiber, which not only enhance household nutrition but also generate revenue for millions of rural families. …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 2, 2025 · pp. 40–56 Read article
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Enhancing Production Line Efficiency: Simulating and Optimizing Single and Parallel Line Processes
Abstract: During a time of fast-paced industrial growth, increasing production line effectiveness is a core issue for manufacturers looking to maximize output, reduce waste, and stay competitive. This study explores the use of simulation-based optimization methods to enhance single and parallel production line designs. Stepping beyond traditional trial-and-error methods, the research utilizes Siemens Tecnomatix Plant Simulation to simulate actual manufacturing scenarios, considering intricacies like buffer capacities, machine sequencing, and event-driven scheduling. …
Published in Journal of Production Research & Management · Vol. 15, Issue 1, 2025 · pp. 22–32 Read article
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Cervical Cancer: Understanding Its Causes, Risk Factors, and Preventive Measures
Abstract: Cervical cancer is a form of cancer that begins in the cervix, the lower portion of the uterus, due to abnormal cell growth that can spread or invade other areas of the body. In its early stages, cervical cancer usually shows no obvious symptoms, which is why regular screenings are essential for detecting it early. As the cancer advances, symptoms such as pelvic pain, unusual vaginal bleeding, and pain during …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 26–30 Read article
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The Role of Artificial Intelligence in Mental Health: Applications in Neurodegenerative Disorders
Abstract: Artificial intelligence (AI) has significantly changed many aspects of medical care, particularly the early evaluation, therapy, and management of neurodegenerative illnesses like Alzheimer's, disease, Parkinson's diseases, and Huntington's diseases. The current research explores the application of AI in mental health with respect to neurological disorders, especially advancements in cognitive examination, neuroimaging analysis, predictive modeling, and customized therapy modalities. Artificial intelligence (AI) systems have shown enormous potential in detecting minute biomarkers …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 34–40 Read article
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Chronic Obstructive Pulmonary Disease (COPD) in Younger Adults: Challenges and Considerations – A Review
Abstract: Chronic Obstructive Pulmonary Disease (COPD) phenomenon rapidly converting into chronic significant health issues for many young adults. A disease calculated for older age gives way to early-onset COPD, which creates new issues for diagnosing and treating the illness and even interacts with the quality of life. The article reviews the epidemiology, risk factors, pathophysiology, clinical presentation, and treatment considerations related to this set of conditions. From those risk factors, early-onset …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 08–19 Read article
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Progression of Health and Wellness: Artificial Intelligence (AI) and Deep Learning (DL) for Precision Medicines
Abstract: Deep learning and artificial intelligence in the field of precision medicine is revolutionizing healthcare to make personalized therapeutic approaches desirable based on the unique characteristics of the patient. AI technologies improve diagnostic accuracy by analyzing medical data, spotting patterns and anomalies that human experts may miss. AI-driven models are instrumental in precision medicine, where they can predict patient response to therapies to tailor treatment plans, enhancing outcomes and reducing adverse …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Lifestyle Factors and Perceptions of Diabetes Among Individuals in North India
Abstract: Background: Diabetes mellitus is influenced by a complex interplay of genetic, environmental, and lifestyle factors. In North India, unique socio-cultural and dietary patterns shape individual behaviors and perceptions toward diabetes. Understanding these lifestyle choices and cultural beliefs is critical for designing interventions that improve adherence to medical treatment and promote healthier outcomes. Methods: A cross-sectional survey was conducted among 1,500 individuals diagnosed with diabetes across selected urban and rural districts …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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Drug Repurposing of Anticancer Agents JP-8g and REDX05358 Against the Target Protein Plectin 1a in Epidemolysis Bullosa Simplex with Muscular Dystrophy (EBS-MD)
Abstract: Epidermolysis Bullosa Simplex with Muscle Dystrophy is a genetic disease affecting the skin and muscles which can be seen at birth or start at adulthood due to the mutation in the protein Plectin 1a (PLEC gene) causing skin blisters and muscle weakness. This protein is seen in sarcolemma, Z disks in skeletal muscles, hemidesmosomes in skin and cardiac muscles giving stability to cytoskeleton, playing a crucial role in neuromuscular transmission …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 22–34 Read article