Search
701 articles for “3-(4”
-
Authentication of a Rapid RP-HPLC technique for Quantification of Remogliflozin and Metformin in Medicinal Formulations
Abstract: A new, precise, and stability-assessing advanced liquid chromatography (HPLC) technique for simultaneous quantification of Remogliflozin and Metformin in fixed dose pharmaceutical formulations was designed and verified. Optimization of the technique was carried out on flowing phase composed of ethanenitrile and buffer, under isocratic conditions, the resolution of peak being sharp with retention times of 3.24 min and 4.89 min for Remogliflozin and Metformin, respectively. Technology suitability was confirmed by the …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 70–77 Read article
-
First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal
Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
-
Intelligent Management of Construction Projects: The Nexus of Human and Artificail Expertise
Abstract: Conversations about digitalization and artificial intelligence (AI) have continued to gain traction in the project management discourse. Although human expertise remains the hallmark of professionalism in the construction industry, AI has emerged as the newest wave of digital technological innovation, which can significantly elevate human productivity in the performance of project management functions. However, for project management professionals in the Nigerian construction industry, the potential of AI is both thrilling …
Published in Journal of Production Research & Management · Vol. 15, Issue 3, 2025 · pp. 16–24 Read article
-
A Survey of Usage and Awareness of E-Resources Among University Library Users at B.R.A. Bihar University, Muzaffarpur, Bihar
Abstract: This study investigates the usage and awareness of e-resources among university library users at BRA Bihar University, Muzaffarpur. The primary purpose of the research is to assess how well users are informed about available electronic resources and to evaluate their usage patterns in academic activities. A quantitative survey was conducted among library users to gather data on their awareness of e-resources, their preferences for specific types of resources, and the …
Published in Journal of Advancements in Library Sciences · Vol. 12, Issue 3, 2025 · pp. 46–56 Read article
-
A study of The impact of Antibiotic Pollution and The types of Environmental Pollution It causes
Abstract: Antibiotics are essential biological drugs for human health and are the cornerstone of treating infections caused by various bacteria and viruses. However, they also pose a significant risk if misused, as each antibiotic is designed for a specific type of bacteria. Sometimes, due to the evolution of bacteria, many antibiotics have become ineffective and resistant to contamination and infection. Therefore, they can have the opposite effect, polluting the environment instead …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 41–46 Read article
-
AI-Integrated Graphene-Modified Polymer Interfaces for Real-Time Crack Detection and Autonomous Healing in Smart Concrete Structures
Abstract: This study presents the design and development of a graphene-reinforced multifunctional polymer composite interface engineered for structural reinforcement, self-sensing, and autonomous healing applications in cementitious systems. A thermosetting polymer matrix embedded with graphene nanoplatelets (0.25–1.5 wt.%) was developed to establish a conductive polymer nano-composite network. Electrical characterization confirmed a distinct percolation threshold at ~0.6–0.8 wt.%, beyond which a sharp increase in conductivity was observed due to the formation of interconnected …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 30–42 Read article
-
Experimental Investigation of Aerodynamic Characteristics of Dimpled 3D Aircraft Wing
Abstract: There is a strong demand for innovative designs, optimization of the aircraft components for their parts with respect to design, etc. One such innovation is by introduction of dimples in the wing of the aircraft. To study the effect of geometry modification of the wing, the present work compares the aerodynamic efficiency, ratio of lift to drag coefficients, along with different aerodynamic characteristics of an Inward and outward circular dimpled …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 1, 2023 · pp. 11–22 Read article
-
Knowledge, Awareness, and Perceptions of Cervical Cancer and Screening Among Women in Rural South India
Abstract: Background: Cervical cancer is still a major public health problem in South India, with rising figures of morbidity and mortality, in spite of progress in prevention, early detection, and treatment. Cervical cancer is the second leading cause of death due to cancer among Indian women, with around 123000 new cases and 67000 deaths every year. The delay in diagnosing CVD and low participation in screening programs is due to poor …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 1–8 Read article
-
Antifungal Susceptibility Pattern of Candida Species Isolates from Dehradun City Hospitals
Abstract: The present investigation on the topic entitled “Antifungal susceptibility analysis of Candida species isolates from Dehradun City hospital.” was accomplished in the Doon University Microbiology laboratory (P.G.) and Hospital, Dehradun, Uttarakhand, during the period of February 2021 to July 2021. A total of 42 clinical samples were collected from patients, suspected of candidiasis from Dehradun city hospitals. Clinical samples were collected from oral cavity, blood, vaginal fluid and urine of …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 Read article
-
Breast Cancer Screening Awareness and Participation Among Women in North India
Abstract: Breast cancer is the most prevalent malignancy among Indian women, accounting for 25% of all female cancers (ICMR, 2020). Significant urban-rural disparities in screening persist across North India due to socioeconomic, cultural, and healthcare access barriers. This study evaluates these disparities to inform targeted interventions. A cross-sectional study was conducted among 1,500 women (750 urban, 750 rural) in Delhi, Uttar Pradesh, Punjab, and Haryana, using stratified random sampling. Data were …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 43–50 Read article
-
Design and Simulation of Forging Die Towards Improving Life of Closed Die
Abstract: Forging is the metal forming process which is used for forming complex shaped component with geometrical accuracy. More than fifty percent of the forgings are processed through this way. Forged components required in many engineering sectors, most of them in the automotive sector. The majority of the safety critical component and load bearing structural components are process through it. By using forging process production of complex component is faster with …
Published in Journal of VLSI Design Tools and Technology Read article
-
Assessing Digital Literacy among the Oraon Tribe of Jharkhand: A Study
Abstract: Digital literacy is essential for inclusion and socioeconomic empowerment in the digital era. This study examines the digital literacy levels of the Oraon tribe in Jharkhand, with a focus on identifying skill gaps, demographic disparities, and barriers to digital access. A mixed-methods approach was employed to gather data from respondents in the Ranchi district, utilizing structured questionnaires and interviews. Male respondents made up the majority (61.5%), with the largest age …
Published in Recent Trends in Social Studies · Vol. 3, Issue 1, 2026 · pp. 06–12 Read article
-
Antioxidant activity of Passiflora foetida leaf extracts and silver nanoparticles in diabetic induced rats
Abstract: The anti-oxidant system present in our body prevents against the free radicals. Anti-oxidants were glutathione peroxidise,serum catalase,vitamin E, ascorbic acid and superoxide. In our study the plant extract of Passiflora foetidae were used to estimate the antioxidant levels in diet-induced diabetic rats. The mean of glutathione peroxide of normal rats was 92.98±1.65. "The mean of diet-induced diabetic rats was 152.50 ± 1.92*. Diabetic rats treated with sitagliptin and vildagliptin had …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 10–16 Read article
-
Molecular Docking Evaluation of Cedrus deodara Secondary Metabolites as a Potent Anti-ovarian Cancer Agent
Abstract: Objective: According to the statistics for the year 2022 it was seen that cancer total cases is 14,61,427. After breast cancer, ovarian cancer is the second most frequent cancer among women. The estrogen receptor (PDB ID: 1X7E), progesterone receptor (PDB ID: 1A28), and Phosphoinositide 3-kinases (PDB ID: 4FJY) can be considered as target protein for ovarian cancer. The plant Cedrus deodara and its phytochemicals were chosen in this study to …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 77–93 Read article
-
Effects of Tendon Gliding Exercises on the Speed of Handwriting Among Female UG Students: Pilot Study
Abstract: Background: Handwriting is an intricate function which requires the combination of fine motor skills, visual and motor coordination abilities, and concentration. Handwriting involves two main movements: horizontal wrist motion and vertical finger movements, along with a rightward translation of the entire arm. Handwriting speed is an important factor in a student’s academic performance, particularly in fields such as statistics. The strength and flexibility of hand muscles can significantly influence writing …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
-
Geotechnical Influence Factors in Empirical Design of Highway Pavement: The A123 Ilorin – Lokoja Highway, Nigeria Case Studies
Abstract: Site investigation and application of geological and geotechnical influence factors on the highway were investigated. Method involved field sampling, geotechnical laboratory and x-ray diffraction analysis and use of SRTM extracted slope and drainage parameters; and their integration in a GIS based multi-criteria decision analysis to derive a subgrade suitability map as a design tool. The suitability criteria classified the highway into four (4) design sections. Section one for very low …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 3, 2024 · pp. 53–70 Read article
-
Effect of Formaldehyde Treatment on the Barrier and Mechanical Properties of Oat Protein Films
Abstract: Oat protein 5% with 40% glycerol as a plasticizer was used to prepare edible films, and formaldehyde was chemically added to the film's solution at four concentrations. The films' barrier and mechanical properties were then investigated. The films were characterized by being medium transparency, homogeneous, odorless, and with a thickness ranging between 0.12 and 0.15 mm. It was also observed that the water vapor permeability decreased whenever the concentration of …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 1–8 Read article
-
Autonomous Agentic AI for Adaptive Cure Optimization and Defect Prevention in Thermoset Polymer Composite Manufacturing
Abstract: Thermoset polymer composites occupy a central position in modern structural manufacturing, from aircraft fuselages to wind-turbine blades. Despite progress in resin chemistry and fiber architecture, the “cure process” that transforms compliant preforms into load-bearing structures remains difficult to manage. Manufacturers encounter ‘voids’, “interlaminar delaminations”, and “spring-back distortion” when curing complex or thick-section parts. The cause is not ignorance of the relevant physics, but rather that ‘temperature’, ‘chemistry’, ‘rheology’, and ‘mechanics’ …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 301–320 Read article
-
Sudarshan Kriya Intervention and Rise of Protective Prostaglandins in Advanced-Stage Breast Cancer: Double-Blind, Randomized, Controlled Trial
Abstract: Background: Breast cancer patients in advanced stages of cancer are managed by palliative care. This study reports important prostaglandin changes observed with added intervention of Sudarshan Kriya in their ongoing palliative care. Level of Prostaglandin A₂ (PGA₂) indicates tumor growth suppression; its level rises if person’s general condition is good, physically fit and active while PGE₂ and D₂ are considered pro-inflammatory. Quantitative assessment of Prostaglandins was done pre and post …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 62–68 Read article
-
Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article