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1777 articles for “design methods”
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Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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Design Process and Methodology for Engineering Product Development
Abstract: Engineering design process is a very important field in developing an engineering product. It guides the engineer in productive thinking. The steps involved and stages in the development of an engineering product is determined by the design process. Engineering design process was developed and is still being developed for the process of achieving better products in the market and also for standardization. For instance, every engineering product must undergo analysis …
Published in Journal of Production Research & Management · Vol. 12, Issue 3, 2022 · pp. 46–52 Read article
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A Critical Review of Generative Design Methods in Computer-Aided Drafting
Abstract: In the realm of Computer-Aided Drafting (CAD), generative design methods have become a potential strategy for automating and enhancing the design process. These methods generate a wide range of design possibilities based on given characteristics and limitations by using algorithms and computational tools. The objective of this critical study is to assess the benefits, drawbacks, and implications of generative design techniques in CAD. A notable result of this merger is …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Modern Computer-aided Drug Design Methods: A Review
Abstract: Computer-aided drug design (CADD) has emerged as a crucial tool in the drug discovery process, offering a time-efficient and cost-effective approach to identifying potential drug candidates. This review aims to provide an overview of modern CADD methods, including high-throughput screening (HTS), structure-based drug design (SBDD), ligand-based drug design (LBDD), structure-based virtual screening (SBVS), and ligand-based virtual screening (LBVS). We discuss the basic principles, applicability, and limitations of each method, highlighting …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 14–20 Read article
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A Constraint-Driven Generative Design Methodology for Modular Actuated Robotic Components in Decentralized Manufacturing
Abstract: This work formalizes a constraint-driven generative design framework for actuator-integrated robotic components intended for decentralized additive manufacturing. Conventional topology optimization typically prioritizes structural efficiency while treating actuator integration, modular interfaces, and fabrication constraints as secondary considerations. In contrast, the proposed methodology encodes these requirements as first-order geometric and mechanical constraints prior to automated material redistribution. The framework defines preserved actuator geometry, bounded design envelopes, representative loading abstractions, and manufacturability-aware domains …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 4, Issue 1, 2026 · pp. 1–12 Read article
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Designing Methodology for Identifying Different Types of Influx Entering in a Well Bore during Drilling and Study of Influx Behavior
Abstract: Drillers frequently encounter kick in drilling operations. Kick refers to the unwanted entry of formation fluid into the well bore. Primary well control and secondary well control are used to control influx entry into a well during drilling operations. Primary well control refers to making the overbalance by the hydrostatic pressure exerted by drilling fluid on the formation pressure. Secondary well control refers to controlling the kick through the use …
Published in Journal of Petroleum Engineering & Technology · Vol. 6, Issue 3, 2016 · pp. 7–11 Read article
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Autonomous Optimization, Method Design of Casting and Its Experimental Validation: A Case Study
Abstract: The metal casting is a complicated but a mass production manufacturing technique. But on the otherhand, the chances of casting rejection are also more if proper attention is not made at every stage ofcasting production. In the metal casting process, higher yield and minimum defects level are expectedby the foundry industries. In the present global and competitive world metal casting industries needsto perform efficiently with a reduction in rejections. This …
Published in Trends in Machine design · Vol. 8, Issue 1, 2021 · pp. 1–10 Read article
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Empirical Method of Designing a Coaxial Line
Abstract: AbstractThis paper is meant to give a concise and correct method to design a coaxial cable using standard design formula. Simulation is done using empirical methods designing of coaxial transmission line. The coax is designed with a cut-off frequency of 1 GHz in TEM mode. The characteristic impedance of the coax is 50Ω. The aim here is to help the reader design a correct coaxial cable at the port of …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 8, Issue 3, 2020 · pp. 33–36 Read article
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Analysis of Braggs Grating for photonics application
Abstract: The plane wave expansion approach was used to optimise reflectance in a Braggs grating on a silicon on insulator structure at wavelength 1.55µm. When the results were compared to the experimental results, it was discovered that they agreed better than any other present results. Aside from the inherent benefits of FBGs, such as low cost, low losses, polarisation insensitivity, and full compatibility with fiber-optic systems, they have demonstrated that by …
Published in Journal of Microwave Engineering and Technologies · Vol. 9, Issue 1, 2022 · pp. 32–35 Read article
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Integral Sliding Mode Control: A Review of Applications
Abstract: Integral Sliding Mode Control (ISMC) has emerged as a robust and efficient method for handling nonlinear systems with uncertainty, turbulence and external disturbances. This study provides a detailed review of ISMC and its design foundations, design methods, practical application aspects and recent developments are included. ISMC design methodology is explored, to be extended with various design methods with different design methods. Recent advances in research, chatter reduction techniques, applications in …
Published in International Journal of Advanced Control and System Engineering · Vol. 2, Issue 1, 2024 · pp. 25–35 Read article
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Methodology of Standard Cell Library Design in .LIB Format
Abstract: The importance of standard cell library design methodology is growing with very-large-scale integration (VLSI) technology advancement due to its usage in VLSI EDA synthesis flows. In this paper, to best of our knowledge and information in any published literature no systematic method of standard cell and creating appropriate co-laterals. In this paper the standard cell design methodology, layout topology, methodology for creating characterized timing table has been developed using 250 …
Published in Journal of VLSI Design Tools and Technology · Vol. 4, Issue 1, 2014 · pp. 30–38 Read article
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Precipitable Water for Human Consumption in Rural Areas: Calculation Method and Engineering Design
Abstract: This work describes a methodological process to estimate the precipitable water for human consumption as a function of meteorological parameters like ambient and dew point temperature, water vapor and ambient pressure, and relative humidity. The paper uses empirical correlations to determine the most accurate procedure for atmospheric rainwater, resulting in a simple relation between precipitable water and dew point temperature as the highest accurate one. The study shows the dew …
Published in Journal of Water Resource Engineering and Management · Vol. 11, Issue 3, 2024 · pp. 41–57 Read article
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Optimisation of Electrocoagulation Flocculation Treatment of Laundry Greywater with Design of Experiment Methodology
Abstract: It is becoming increasingly more important to relook at the impact that greywater has on the environment and the opportunities that it can provide for water re-use. More especially that the sewer pipelines are often over flooded and overflowing onto the streets in most townships in South Africa due to sewer blockages, population, and wastewater treatment plants (WWTP) overcapacity. To cope with current and future wastewater treatment (WWT) demands, developments …
Published in Emerging Trends in Chemical Engineering · Vol. 8, Issue 3, 2021 · pp. 41–58 Read article
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A Note on Vaccine Design Using Bioinformatics Methods and Applications
Abstract: Vaccines prevent infectious diseases caused by viruses and bacteria saving millions of lives.It consists of certain agents that resemble disease causative agentsand stimulates our immune system to recognize and fight foreign antigens. Immune function or an immune response is the fundamental basis of the vaccine's mechanism. Vaccines are pharmaceutical derivatives that provide an affordable way to prevent diseases.Various bioinformatics approaches can be incorporated into vaccine design studies and development. Reverse …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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A Comprehensive Review of CMOS Analog Circuit Design Techniques for Low-Power VLSI Systems
Abstract: CMOS analog circuit design plays a significant role in the development of modern low-power Very Large-Scale Integration (VLSI) systems used in wireless communication, biomedical devices, portable electronics, embedded systems, and Internet of Things (IoT) applications. Research on low-power CMOS analogue design methodologies has intensified because to the growing need for high-performance, small, and energy-efficient electronic products. However, reducing power consumption while maintaining signal accuracy, noise performance, stability, bandwidth, and overall …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 4, Issue 1, 2026 Read article
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Cost Comparison of Post Tensioning, Prestressing and Conventional RCC Design
Abstract: The aim of project is to check the cost effectiveness of Post-Tensioning Slab with other design methods. For that purpose multipurpose hall is chosen with the footprint of 6 x 8 m having the total slab area is (768 sq. m). The analysis done by hand calculation and using the following methods: 1) Flat Plate (Without Drop and capital ) and Post-Tensioning Slab by using equivalent frame methods 2) Flat …
Published in Journal of Construction Engineering, Technology & Management · Vol. 5, Issue 2, 2015 · pp. 1–8 Read article
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Evaluating TRIZ Methodology in the Conceptual Design Phase of Industrial Products
Abstract: The Theory of Inventive Problem Solving (TRIZ) has emerged as a powerful systematic innovation methodology that enhances creativity and problem-solving efficiency in engineering design. This paper evaluates the application of TRIZ during the conceptual design phase of industrial products, where early-stage decisions critically influence functionality, cost, sustainability, and market competitiveness. TRIZ provides designers with structured tools—such as the 40 Inventive Principles, Contradiction Matrix, Su-Field Analysis, and Trends of Technological Evolution—that …
Published in International Journal of Industrial and Product Design Engineering · Vol. 3, Issue 2, 2025 · pp. 27–32 Read article
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Twisting, Super Twisting and Adaptive Algorithm Sliding Mode Controller for Second Order Time Delay Systems
Abstract: The sliding mode control approach is widely considered as one of the most effective methods for designing a reliable controller for a complicated higher-order dynamic plant operating under uncertainty. The primary advantages of sliding mode is its low sensitivity to changes in plant parameters and the ability to entirely eliminate disruptions. Sliding mode control has been widely applied as a robust control design methodology that is completely insensitive to uncertainties, …
Published in Current Trends in Signal Processing Read article
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Twisting, Super Twisting and Adaptive Algorithm Sliding Mode Controller for Second Order Time Delay Systems
Abstract: The sliding mode control approach is widely considered as one of the most effective methods for designing a reliable controller for a complicated higher-order dynamic plant operating under uncertainty. The primary advantages of sliding mode is its low sensitivity to changes in plant parameters and the ability to entirely eliminate disruptions. Sliding mode control has been widely applied as a robust control design methodology that is completely insensitive to uncertainties, …
Published in Current Trends in Signal Processing · Vol. 11, Issue 2, 2021 · pp. 10–27 Read article
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Hierarchical Methodology Approach to SOC Design: A Comprehensive Look
Abstract: The design scale of a chip has increased many folds in the last few years and shows a continuous exponential trend. This is made possible by the reduction in transistor size and an evolving process technology. As a result, it is possible to move to SoC technology (System on Chip-A single die consisting of multiple subsystems) rather than a traditional ASIC. This has obviously resulted in an increase in the …
Published in Journal of VLSI Design Tools and Technology · Vol. 10, Issue 3, 2020 · pp. 35–42 Read article