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23 articles for “Angiogenesis”
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Phytochemicals from Plectranthus amboinicus and Azadirachta indica for Promoting Angiogenesis and Tissue Regeneration – A Short Review
Abstract: The eco-friendly synthesis of silver nanoparticles (AgNPs) using plant extracts has garnered significant attention due to its potential in biomedical applications. This review highlights the green synthesis methodologies, focusing on Plectranthus amboinicus and Azadirachta indica, their phytochemical components, and their docking studies with angiogenesis-related receptors such as VEGF and FGF. The applications of AgNPs in tissue regeneration, wound healing, and angiogenesis are discussed in detail, emphasizing the roles of phytochemicals …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 2, 2025 · pp. 34–40 Read article
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Recombinant Human EGF in Wound Healing: 3D Computational Insights
Abstract: A Growth Factor represents a naturally-occurring compound with the remarkable ability to incite cellular growth, proliferation, and differentiation. Typically manifesting as either a protein or a steroid hormone, these factors wield significant influence over an array of cellular activities. Their pivotal role lies in the regulation of diverse cellular processes, often serving as catalysts for cell specialization and maturation, a characteristic that distinguishes them from one another. For instance, bone …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 6–10 Read article
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Harnessing Honeybee Venom For Cancer Treatment: A Natural Remedy In Oncology
Abstract: Honeybee venom (HBV) has harvested significant attention as a promising natural compound with therapeutic potential in cancer treatment. This review investigates deeply into the current scientific understanding of honeybee venom, focusing on its anticancer mechanisms, molecular interactions, and potential clinical applications. Honeybee venom comprises various bioactive components, including melittin, apamin, phospholipase A2, and other peptides, which exhibit a wide range of biological activities. Recent research has demonstrated its ability to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 10–14 Read article
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The Dental Pulp: Vital Core of Tooth Functionality
Abstract: Dental pulp, an intricately specialized mesenchymal tissue, possesses limited regenerative capabilities attributable to the unique anatomical arrangement and the post-mitotic nature of odontoblastic cells. The process of complete pulp amputation, subsequent disinfection of the pulp space, and the insertion of synthetic materials results in the substantial loss of dentin, leading to enduring consequences such as a non-vital and structurally weakened tooth.Nevertheless, a beacon of hope emerges in the form of …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 Read article
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Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, movement, and growth of certain cells. This process is essential for tumors to grow and spread to other parts of the body. This study focused on evaluating the binding …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Platelets A Tiny Cell Fragments
Abstract: Platelets are disc-shaped, anucleate cells that are approximately 2-3 μm in diameter. Their primary function is to control hemostasis, or blood clotting, but they also play important roles in angiogenesis (the formation of new blood vessels) and innate immunity (the body's first line of defence against infection). With a diameter of just 2-3 microns, platelets are tiny, disc-shaped cells that lack a nucleus. While their main responsibility is to ensure …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 22–28 Read article
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Recent Advancements in Nanobiocomposite-Based Wound Healing and Tissue Regeneration
Abstract: Haemostasis, inflammation, proliferation, remodeling, and other highly coordinated cellular and molecular activities are all part of the complex biological processes of wound healing and tissue regeneration. Following an injury, these stages cooperate to restore tissue integrity and function. However, this normal process is disturbed in many clinical circumstances, especially chronic wounds such diabetic ulcers, burns, and pressure sores. Prolonged inflammation, chronic microbial infection, diminished angiogenesis, and impaired extracellular matrix production …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 297–318 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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Navigating the Depths of Cancer Stem Cells: Unraveling Resistance Mechanisms and Emerging Therapeutic Strategies
Abstract: In the past few decades, comprehensive evidence has convincingly established the presence of cancer stem cells (CSCs) as a minor subset within tumors, contributing to an unusually elevated level of cellular diversity within the malignancy. CSCs are functionally identified by their capacity for self-renewal and differentiation, frequently influenced by signals from their surrounding microenvironment. The interconnected transcriptional, post-transcriptional, metabolic, and epigenetic regulatory networks govern the biological characteristics of CSCs. CSCs …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
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Unlocking The Bioactivity Potential: Molecular Insights and Predictions of Salen, Salophen, Allicin, Curcumin, and Piperine
Abstract: In this work, the prediction of the biological activity of several significant molecules, including salen, salophen, allicin, curcumin, and piperine, are discussed. Using Molinspiration software, the molecular properties of these compounds were calculated. These molecules are highly significant due to their extensive potential in medical applications. Salen and salophen, for instance, play crucial roles in cancer chemotherapy and act as inhibitors of angiogenesis. Curcumin is renowned for its antioxidant properties, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 2, 2023 · pp. 14–21 Read article
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Towards smart cancer care - AI enhanced monitoring and intervention
Abstract: According to estimates from the World Health Organization (WHO) for 2022, cancer is one of the leading causes of mortality, accounting for roughly 16% of all deaths globally. The goal of the cancer community is to improve the lives of those who are impacted by cancer and to cut the cancer death rate in half during the next several years. If cancer is identified early and treated, its impact on …
Published in Journal of Microwave Engineering and Technologies · Vol. 12, Issue 1, 2025 · pp. 38–44 Read article
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Nutraceuticals as Adjunctive Treatment in Cancer Exploring Efficacy and Mechanism of Action
Abstract: Dietary habits are a critical factor in cancer prevention, with plant-based diets rich in vegetables and fruits associated with reduced cancer risk. Nutraceuticals—bioactive compounds derived from food and supplements—have gained attention for their potential in cancer prevention and therapy. Phytochemicals such as flavonoids, polyphenols, and alkaloids exhibit anti-cancer properties through mechanisms including antioxidant activity, anti-inflammatory effects, inhibition of tumor growth, and induction of apoptosis. Key nutraceuticals include alkaloids (e.g., caffeine, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 35–45 Read article
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QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
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Role Of Autologous Platelet-Rich Plasma (APRP) In Take of Graft
Abstract: Autologous platelet-rich plasma (APRP) has gained attention as a promising adjunct in skin grafting procedures, particularly in enhancing the take and healing of grafts in burn patients. This study focuses on the application of APRP to improve the adherence of split-thickness skin grafts (STSG) in a pediatric patient with scald burns. APRP is prepared by concentrating the patient’s platelets from a small volume of blood, which is rich in growth …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 1, 2025 · pp. 1–5 Read article
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Formulation, Evaluation and Development of Multipurpose Cream Containing kokum Butter
Abstract: The creation of the multipurpose polyherbal crack-healing cream, which shields the skin from cracks and can also serve as a multifunctional cream to shield the skin from other skin issues. The polyherbal cosmetic formulation can be used to give skin a protective barrier and is safe to use. Over the course of the study, this multipurpose polyherbal cream demonstrated good homogeneity, pH, consistency, spreadability, and lack of phase separation. This …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 78–89 Read article
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Lesser-Known Metabolites Influencing Ovarian Function, Follicular Development, and Embryo Viability in Dairy Cows
Abstract: The intricate processes of ovarian function, follicular development, and embryo viability in dairy cows are tightly regulated by a complex network of metabolites. While conventional biomarkers, such as steroid hormones, amino acids, and glucose metabolites, have been extensively studied, a growing body of evidence suggests that lesser-known metabolites play pivotal roles in bovine reproductive physiology. Dairy cattle fertility is critical for maintaining optimal milk production and herd sustainability, necessitating deeper …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 18–29 Read article
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Exploring Recent Advancements in Nanomedicine for Tumor Microenvironmental Tissue Engineering
Abstract: The combination of tissue engineering and nanomedicine is transforming cancer treatment by offering creative ways to get around problems with conventional therapies. Recent developments in nanomedicine are examined in this review, with an emphasis on how they might be used to comprehend and control the tumor microenvironment (TME), a dynamic and complex environment that has a major impact on the course of cancer and the effectiveness of treatment. Targeted interactions …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 122–136 Read article
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Nanomedicine in the Tumor Microenvironment: Physiological Modulation Through Tissue Engineering Approaches
Abstract: The integration of nanomedicine and tissue engineering offers transformative strategies for cancer therapy by directly modulating the physiological processes within the tumor microenvironment (TME). This review emphasizes recent advances in nanomedicine that enable precise drug delivery, controlled release, and real-time monitoring of key physiological parameters influencing tumor progression, angiogenesis, and immune evasion. Tissue-engineered 3D tumor models provide physiologically relevant platforms that better mimic in vivo conditions than traditional 2D cultures, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 19–31 Read article
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Immune Dysregulation and Cytokine Circuitry in Genital Endometriosis: Mechanistic Insights and Next-Generation Immunotherapeutic Strategies
Abstract: Genital endometriosis is increasingly recognized as an immune-mediated inflammatory disorder driven by complex interactions between dysregulated immune cells, cytokine hubs, and microbiome-derived modulators. This review introduces a novel “immune–cytokine circuitry” framework that unifies innate and adaptive immune abnormalities with key cytokine loops sustaining chronic inflammation, angiogenesis, neuroinflammation, and immune tolerance. Within this circuitry, macrophage polarization, dendritic cell immaturity, NK-cell anergy, Treg expansion, Th17 amplification, and B-cell–mediated autoimmunity converge to establish …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 06–16 Read article
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Impact of Hypoxia on Cardiopulmonary Adaptation in Canines: A Comprehensive Review
Abstract: Hypoxia triggers a series of cardiopulmonary responses that play an important role in oxygen delivery and the continuation of physiological activity in mammals. Canines are also a useful translational model of study to examine these adaptive responses because of their anatomical, physiological, and cardiopulmonary differences with humans. This review summarizes the experimental data of acute, subacute and chronic hypoxia in dogs with particular focus on the variations in cardiac functioning, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 · pp. 13–24 Read article