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431 articles for “rat model”
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Comparative Analyses of Select Microbial Growth Inhibited Rate Models
Abstract: Food waste is a complex substrate comprising of different mixtures of chemical compounds. The growth rate of micro-organism in such environment will experience inhibition. Consequently, the Monod’s model will not be able to describe the growth rate of its bacteria. The Aiba’s, Andrews and the Haldane’s growth rate models that are accounts for growth rate of bacteria with inhibition were compared. To do this, seven different batch experimentations; each with …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 16–24 Read article
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Using of Rat Model Over Other Species: A Review
Abstract: The first domesticated morphological features to be used in studies were rats. Scientists employed the brown rat Rattus norvegicus to study human biology and therapeutics two decades ago, focusing on the consequences of hunger and oxygen deprivation. Rats have been used to answer a wide range of basic science problems relevant to common human ailments in the fields of pharmacology, immunology, physiology, nutrition, behaviour, learning, and toxicity. The article gives …
Published in International Journal of Animal Biotechnology and Applications Read article
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A research study into the interactions between the monoherbal formulations of arjuna and Aloe vera in a rat model of isoproterenol-induced cardiotoxicity
Abstract: Aloe vera is a herbal dietary supplement, and arjuna is used for its cardioprotective properties. Rats were given isoproterenol hydrochloride subcutaneously to cause myocardial infarction. The purpose of the study was to identify any potential pharmacodynamic interactions between the commercially available formulations of Aloe vera and arjuna. Materials and Procedures: The electrocardiogram (heart rate, ST segment elevation time, QRS complex amplitude), serum cardiac markers (creatine kinase, isoform of creatine kinase, …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 1–10 Read article
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Changes of the Function of Interstitial Cells of Cajal and Fecundity During Chronic Salpingitis: Experimental Study
Abstract: We have conducted this study to clarify the changes of the function of interstitial cells of Cajal and fecundity in chronic salpingitis white rat models which are made by infecting its vaginal cavity with Chlamydia. Background: Chlamydial infection is a sexually transmitted disease which is caused by Chlamydia trachomatis. 75% of the fallopian tube disease is thought to be due to anamnesis of asymptomatic Chlamydial infection and those who are …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 23–26 Read article
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Describing Microbial Growth Rate in Solid Suspended Media using Monod and Haldane Models
Abstract: This work details the procedure for curve fitting the Monod and Haldane’s growth models in for solid suspended media such as food waste; in order to determine their parameters for solid suspended media such as food waste. Seven different batch runs; each with initial substrate concentration were studied at constant temperature. A modified method was used to quantify the mass of microbes during the rection process and data obtained were …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 11, Issue 1, 2024 Read article
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Assessing Urban Surface Runoff Management Using the SWAT Model, GIS, and the Rational Method: A Case Study of Karapakkam
Abstract: Urban surface runoff management encompasses strategies aimed at regulating rainwater flow, reducing urban flooding, enhancing groundwater recharge, and contributing to disaster risk mitigation for sustainable urban development. This study seeks to optimize surface runoff management in urban settings by using the soil and water assessment tool (SWAT) model integrated with geographic information systems (GIS) to minimize flood risks. The research focuses on the peak runoff in Karapakkam, a locality within …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 4, Issue 1, 2026 · pp. 37–48 Read article
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Model to Predict a Ratio Control of Hydrocarbon Acid and Water in a Packed Bed Reactor
Abstract: Model development was carried out to examine the ratio of hydrochloric acid gas and water in a packed bed reactor. The research predicted increase in output with increase in time, revealing the effectiveness ratio control of hydrochloric acid separation from water using absorption column mechanism. The density of the products played an active role in the separation process as well as in control action function. The developed model can be …
Published in Emerging Trends in Chemical Engineering Read article
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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A Study on the Influence of Cashew and Pawpaw Leaf on Soil Density Treatment of Contaminated Swampy and Clay Soils
Abstract: Soil density is a key parameter in assessing soil health and structure, often employed as a potential index in bioremediation studies. This study investigates the impact of bioremediation treatments using Cashew Leaf (Anacardium occidentale) and Pawpaw Leaf (Carica papaya) on the density of swampy and clay soils over time. The results show that both treatments, in varying quantities, influence the soil's density by reducing the post-contamination density to levels closer …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 1–9 Read article
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Modeling the Novel Coronavirus Disease (COVID-19) as Hidden Markov Chains
Abstract: The Hidden Markov Model has over the years been an appropriate method for modeling diseases such as HIV AIDS, heart failure, and so on. With the ongoing pandemic affecting Nigeria by being responsible for 2,745 death cases out of 207,616 confirmed cases as of October 10, 2021, the need to study an important parameter of COVID-19, the case fatality rate by building a model and estimating the case fatality rate …
Published in Research & Reviews : Journal of Statistics Read article
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A Comparative Review of AI-driven 3D Modelling for Simplified Photogrammetry and Object Acquisition
Abstract: The field of photogrammetry, historically reliant on guide strategies, is undergoing a transformation with the emergence of AI-powered 3d modeling answers. This assessment work delves into this evolving panorama by using evaluating and comparing various AI-pushed gear presented by means of exclusive businesses. The study in particular makes a specialty of their effectiveness in simplifying photogrammetry workflows and facilitating the acquisition of 3D gadgets. The analysis contains a diverse range …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 2, 2024 · pp. 21–32 Read article
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Continuous-Time Modelling of the Two-Input Fourth Order DC_DC Converter
Abstract: Two-input fourth-order integrated (TIFOI) converter is designed to process the power from two different sources Vg1 and Vg2. This converter facilitates regulation of dc-bus voltage and LVS current. In the power conversion process it performs bucking operation for first dc source Vg1, buck-boost operation for the second source Vg2. Power stage dynamics of the TIFOI converters is modeled using the state-space analysis. The system modelling plays an important role in …
Published in Journal of Control & Instrumentation Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Analysis of Gold Price Trend Using the Hidden Markov Model
Abstract: This study aims to analyze the behavior of gold prices in India through a two-state Hidden Markov Model (HMM). We first formulated crucial parameters, such as the Transition Probability Matrix (TPM), Initial Probability Vector (IPV), and Emission Probability Matrix (EPM). Subsequently, we constructed a hidden Markov probability distribution and evaluated Pearson’s coefficients to gauge the correlations separately for each state. The goodness of fit of the developed model was assessed …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 11, Issue 2, 2024 · pp. 7–16 Read article
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Lumped Construction Sequence for Column Shortening Analysis in High Rise Building with Outrigger System
Abstract: The exact value of column shortening is not a straightforward task. Various parameters are affected on column shortening results like rate of construction sequence and reinforcement ratio. The building should stand with high stiffness and must be able to resist lateral deformation without having discomfort to the user. The excessive drift is controlled by using outrigger system. In high rise buildings, the construction sequence analysis and conventional sequence analysis are …
Published in Recent Trends in Civil Engineering & Technology Read article
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Non-Contact Quantification of Swelling-Induced Deformation in Polymer Hydrogels Using Image Analysis
Abstract: Swelling of polymer hydrogels governs transport, mechanics, and functional performance in biomedical systems, yet it is often reported using bulk ratios that conceal spatially heterogeneous deformation and boundary-driven instabilities. This study presents a non-contact image-analysis framework to quantify swelling-induced deformation by tracking shape and boundary evolution from time-lapse imaging. The approach segments the hydrogel region, extracts a sub-pixel refined contour, and computes boundary displacement descriptors including mean and upper-percentile normal …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1499–1509 Read article
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Optimization of Turning Process Parameters by Genetic Algorithm Approach
Abstract: In this research, turning parameters were optimized through a genetic algorithm for the purpose to minimize surface roughness and to maximize the material removal rate. High finish quality is guaranteed through minimum surface roughness, and efficient process planning is facilitated through maximum material removal rate optimization. For predicting surface roughness and material removal rate with respect to spindle speed, feed rate, and depth of cut, the empirical models were developed …
Published in Journal of Production Research & Management · Vol. 15, Issue 1, 2025 · pp. 33–41 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Study on the Variations in Physicochemical Property Concentration in a Contaminated Fresh and Salt Water
Abstract: In this research, the dispersion of crude oil contaminated was subjected into laboratory observations and results were recorded. These results were used to develop and adopt mathematical models for a proper engineering experimental practice. 1.5m3 volumes of fresh water and salt water were filled in two tanks of equal fit at the same intervals along the tanks and depth, where samples were collected for the purpose of analysis of physicochemical …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 2, 2023 · pp. 1–9 Read article
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Numerical Studies on Deep Drawability of the Aluminium Alloy, AA6082 and Parameters Affecting It
Abstract: Deep drawing is a metal forming operation used for manufacturing sheet-metal components for application in the automobile, aerospace, and packaging industries. The objective of the present work was to study the various parameters influencing the drawability of AA6082. The deep-drawing process was modeled and simulated in Ls-Dyna Pre-Post(R) V4.6.17 software. The tensile test was performed according to the ASTM-E8M standard on AA6082-T6 material and subsequently annealed to attain higher ductility. …
Published in Journal of Polymer & Composites Read article