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157 articles for “precision engineering”
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Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article
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Hybrid Machining Processes in Advanced Manufacturing: A Review of Mechanisms and Industrial Applications
Abstract: Hybrid machining processes (HMPs) have gained considerable attention in recent years as an effective approach to address the growing complexity and performance demands of modern manufacturing systems. These processes combine two or more machining techniques—such as mechanical, thermal, chemical, or electrical methods—into a single setup, enabling enhanced productivity, precision, and adaptability, particularly for hard-to-machine materials like ceramics, composites, and superalloys. The integration of distinct energy sources results in synergistic effects …
Published in Journal of Production Research & Management · Vol. 15, Issue 2, 2025 · pp. 19–24 Read article
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New Design Formulae for Safety and Precision in the Fatigue Engineering of Mechanical Components and Structures
Abstract: This paper introduces two new formulae, termed the Nori Fatigue Formulae, for determining the maximum allowable fatigue stress in mechanical components and structures with significant stress concentrations. These formulae will eliminate the usage of code-sensitive safety factors along with other factored values from the entire mechanical design engineering work, ranging from a safety pin to spacecraft. The first formula gives the maximum allowable fatigue stress in tension, and the second …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 6–24 Read article
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Designing and Modeling of Giant Magnetoresistance (GMR) Materials based Devices in Electrical Power and Biomedical Systems
Abstract: This paper presents Designing and Modeling of Giant Magnetoresistance (GMR) Devices in Electrical Power and Biomedical Systems and the related materials. The GMR, inverse GMR, and Spin valve using exchange bias have been analytically derived and discussed from the designing point of view for optimizing the performance of the GMR based Devices in Electrical systems. More recently, GMR has been used in sensors, magnetic memory chips, and hard-disk read-heads. The …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 1, 2025 · pp. 22–32 Read article
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Polymer Chemistry in Medical Devices: A Focus on Injection Syringes
Abstract: Polymers play a crucial role in the medical field, particularly in the development of injection syringes. The use of polymers in syringe manufacturing provides several advantages, including biocompatibility, durability, cost-effectiveness, and ease of mass production. Compared to traditional glass syringes, polymer-based syringes offer enhanced safety by reducing breakability, improving lightweight handling, and enabling precise engineering of syringe components. Various types of polymers are utilized in syringe production, each chosen based …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 436–442 Read article
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Personalized Therapy Using Drug Delivery Devices
Abstract: The persistent challenge in modern medicine lies in inter-patient heterogeneity, rendering standardized drug dosing protocols suboptimal for many chronic conditions. Traditional pharmacokinetics fail to account for real-time biological fluctuations, leading to cycles of ineffective treatment or dose-limiting toxicity. This paper explores the critical intersection of advanced drug delivery devices (DDDs) and personalized medicine, positioning these technologies as the vital link translating genomic and biological data into tangible, patient- specific interventions. …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 53–62 Read article
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Process Optimization of Spot Welding for Galvanized Automotive Steel Sheets
Abstract: Resistance Spot Welding (RSW) is a pillar of the modern automotive industry with the usage of lightweight and high-strength products at the highest point of demand. The optimum weld quality of galvanized steel sheets which is a material of choice because of its additional corrosion protective property is however not achieved easily. This study is a well-developed data-based solution to designing the RSW process in the most efficient way, providing …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 32–42 Read article
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Study of Contact Temperature During Polishing of Zinc Plate with Ultrasonic Vibration Using Single Pole Magnetic Abrasive Finishing
Abstract: The present work scrutinizes the impact of ultrasonic vibration on the contact temperature during polishing zinc plates with Single Pole Magnetic Abrasive Finishing (SPMAF). The efficacy and eminence of FMAB finishing are pointedly influenced by heat generation at the interaction point, as raised up temperatures can lead to the deprivation of abrasive elements or the bonding material inside the brush, which leads to the fading its overall effectiveness. The magnetic …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1239–1247 Read article
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Integrative Structural-Functional Genomics of Fc and Fab: Precision Models for Monoclonal Antibody Stability and Anti-Aggregation Engineering
Abstract: Monoclonal antibodies (mAbs) represent the cornerstone of biotherapeutics, yet aggregation propensity compromises up to 50% of candidates during development, driven by Fab hypervariability and Fc vulnerabilities.(1,2) This review integrates functional genomics from OAS (4B+ sequences)(5) and structural databases (SAbDab: 10K+ structures)(6) with machine learning models achieving R=0.97 for SAP prediction.(11) We dissect biophysical mechanisms, benchmark predictive tools (DeepSP, ESM2), and engineering strategies (YTE, FW mutations) that enhance Tm by 5-10°C …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Advancements in Nanostructured Membranes for Gas Separation: A Comprehensive Review
Abstract: Gas separation is vital in petrochemical, pharmaceutical, and environmental industries, yet traditional methods like distillation and cryogenic separation are energy-intensive and inefficient. Nanostructured membranes present a promising alternative, utilizing nanomaterials such as titanium dioxide, silica, carbon nanotubes, zeolite, and metal-organic frameworks to enhance separation efficiency and selectivity while reducing energy consumption. These membranes fall into various categories: polymeric nanostructured membranes, including mixed matrix and thin-film composites; inorganic membranes, such as …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 31–36 Read article
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An Overview on Quantum dot technology in Temperature sensor design
Abstract: Quantumdot (QD) thermometry harnesses the sizedependent electronic structure of semiconductor nanocrystals to translate minute temperature variations into robust optical signals. In this work we present a systematic design framework for QDbased temperature sensors that integrates (i) bandgap engineering through precise colloidal synthesis, (ii) surfacestate passivation to suppress nonradiative pathways, and (iii) a planar photonicreadout architecture compatible with lowcost, CMOSfriendly fabrication. By exploiting the linear redshift of the photoluminescence (PL) peak …
Published in Journal of Electronic Design Technology · Vol. 17, Issue 1, 2026 · pp. 10–17 Read article
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Statistical Modeling of Heat Transfer and Fluid Dynamics: Application in Mechanical Engineering Design
Abstract: Understanding and optimizing the intricate processes involved in heat transfer and fluid dynamics—two concepts essential to mechanical engineering design—require statistical modeling. Engineers can forecast, regulate, and enhance the performance of systems including heat exchangers, turbines, cooling mechanisms, and different fluid machinery by using statistical approaches. In order to address uncertainties, variability in material properties, boundary conditions, and operational parameters, this work investigates the integration of statistical modeling tools in the …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 2, 2024 · pp. 18–22 Read article
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Nano- Catalysts for Enhanced Performance in Hydrogenation Reactions
Abstract: The development of nano-catalysts has revolutionized the field of hydrogenation reactions, offering unparalleled efficiency and selectivity. This study explores the synthesis, characterization, and application of novel nano-catalysts designed to enhance hydrogenation processes. By leveraging advanced materials science techniques, we have engineered catalysts with precisely controlled particle sizes, shapes, and surface properties. These nano-catalysts exhibit remarkable activity and stability, attributed to their high surface area-to-volume ratios and unique electronic structures. Our …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 1, 2024 · pp. 22–27 Read article
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Robotics and Automation in Mechanical Engineering: Transforming Modern Manufacturing Systems
Abstract: Robotics and automation have significantly transformed mechanical engineering, particularly in manufacturing, precision assembly, and intelligent systems integration. With the advancement of sensors, control systems, artificial intelligence, and mechatronics, robotic systems are now capable of performing complex tasks with high accuracy, repeatability, and efficiency. This article explores the role of robotics in modern mechanical applications, including industrial automation, collaborative robots, predictive maintenance, and smart manufacturing. It also discusses design considerations, challenges, …
Published in International Journal of Manufacturing and Production Engineering · Vol. 4, Issue 1, 2026 · pp. 27–33 Read article
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A Review on Microbial Enzymes in the Food Industry: Current Innovations and Future Prospects
Abstract: Over the past few decades, microbial enzymes have become indispensable biocatalysts in food production, fundamentally revolutionizing how we approach manufacturing processes while simultaneously enhancing the quality of what we produce. Today, approximately 200 of the 4,000 known enzymes are deployed commercially with proteases, amylases, lipases, and lactases leading the charge in industrial food applications. This review brings together the latest innovations in how we use microbial enzymes for food processing, …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 43–53 Read article
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Hyper Personalization Using AI: Elevate Fitness
Abstract: In the modern era, many individuals find it challenging to prioritize their health and well-being due to busy lifestyles filled with work, academic, and personal obligations. Conventional fitness and nutrition programs often apply uniform strategies that overlook individual differences in body type, preferences, and goals. This lack of real-time feedback and contextual customization often leads to poor user engagement and unsatisfactory results over time. Elevate is a comprehensive, AI-powered fitness …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 12, Issue 3, 2025 · pp. 10–21 Read article
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Physics-Informed Generative and Tensor-Based Framework for DNA Sequence Simulation and Genomic Structure Discovery
Abstract: In this paper, we explore the intersection of artificial intelligence (AI) and mathematical physics to propose advanced methods for DNA sequence generation and analysis. Specifically, we investigate how physics-informed Generative Adversarial Networks (GANs) and tensor network representations can be harnessed to restructure DNA for applications in genetic science. The proposed methodology offers a unique integration of concepts of thermodynamic modeling with innovative GAN architecture in order to allow the creation …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 2, 2026 Read article
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Tiny Titans: The Promise of E-Nanorobots in the Fight Against Cancer
Abstract: Cancer, a disease characterized by uncontrolled cell growth, continues to be a leading cause of mortality worldwide. Despite advances in surgery, radiation, and chemotherapy, significant challenges remain in achieving targeted and effective treatments without harmful side effects. But what if we could deploy microscopic robots, engineered at the nanoscale, to precisely target and destroy cancerous cells while leaving healthy tissue untouched. The fascinating possibilities of e-nanorobots are driving extensive research …
Published in Journal of Advancements in Robotics · Vol. 12, Issue 2, 2025 · pp. 11–21 Read article
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Advancements in Molecular Engineering: Innovations at the Nexus of Chemistry and Technology
Abstract: Molecular engineering, a frontier of chemistry, merges precision and innovation to design and assemble molecular structures with unprecedented control. This abstract explores recent advances, highlighting key breakthroughs and their transformative impacts. Starting with its roots in chemical synthesis and materials science, it traces the evolution towards rational design driven by computational tools and advanced characterization techniques, enabling tailored molecular architectures. A focal point is programmable molecules, where DNA nanotechnology principles …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 37–43 Read article
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Scaling of Machine Learning Techniques in Medical Imagining and Biomedical Applications Concerning Healthcare
Abstract: Machine learning refers to a field within computer science enabling computers to learn without explicit programming. Stemming from artificial intelligence's study of pattern recognition and computational learning theory, machine learning develops algorithms capable of learning from vast datasets and making predictions. Its applications span diverse computing tasks like email filtering, network intrusion detection, optical character recognition, and computer vision, where conventional algorithm design proves challenging. Notably, in computer vision, a …
Published in Journal of Computer Technology & Applications · Vol. 15, Issue 1, 2024 · pp. 41–44 Read article