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59 articles for “particle engineering”
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Geotechnical Analysis and Performance Evaluation of Subgrade Materials in Road Construction
Abstract: Geotechnical engineering plays a pivotal role in the design, construction, and long-term maintenance of infrastructure, particularly in road construction, where subgrade conditions are directly linked to pavement performance, durability, and overall structural integrity. The performance of a road is heavily influenced by the geotechnical properties of the subgrade, making it essential to thoroughly assess these properties in the planning and construction phases. This study comprehensively investigates the geotechnical characteristics and …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 3, 2024 · pp. 24–29 Read article
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Squeeze Casting of Hybrid Aluminum Matrix Composites: A Critical Review of Process Optimization, Reinforcement Strategies, and Performance Outcomes
Abstract: Increasing demand for lightweight, performance-oriented components in automotive, aerospace, and defense industries has driven advancements in squeeze casting, a hybrid technique merging forging and die-casting advantages to produce near-net-shape aluminum matrix composites (AMCs) with superior mechanical-tribological properties. This review critically examines the interplay of process parameters (e.g., squeeze pressure: 70–150 MPa, melt temperature: 650–800°C), reinforcement characteristics (volume fraction ≤10%, particle size: 10–71µm), and interfacial engineering strategies (flux-assisted bonding, ultrasonic dispersion) …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 2, 2025 · pp. 52–60 Read article
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Nano- Catalysts for Enhanced Performance in Hydrogenation Reactions
Abstract: The development of nano-catalysts has revolutionized the field of hydrogenation reactions, offering unparalleled efficiency and selectivity. This study explores the synthesis, characterization, and application of novel nano-catalysts designed to enhance hydrogenation processes. By leveraging advanced materials science techniques, we have engineered catalysts with precisely controlled particle sizes, shapes, and surface properties. These nano-catalysts exhibit remarkable activity and stability, attributed to their high surface area-to-volume ratios and unique electronic structures. Our …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 1, 2024 · pp. 22–27 Read article
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Fabrication and Mechanical Characterization of Hybrid Natural Fiber Reinforced Composites using Ferromagnetic and Graphite Fillers
Abstract: The past few years have seen a lot of interest in the creation of hybrid natural fiber composites because of their lightweight properties, environmental friendliness and their potential use in structures. The hybrid composite laminates in the current study were produced by the hand lay-up process by blending the natural fibers with the functional filler materials. Three types of composite structures were created and these are Natural Composite Material (NCM), …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 498–511 Read article
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An Overview of The Impact of Reinforcement on Mechanical and Thermal Characteristics of Aluminum Alloy Composites
Abstract: Aluminum is utilized extensively in the domains of aerospace, electronic technology, electric module packing, automotive body structure, solar and wind energy management, and so on because of its better potential for weight reduction. Strength of aluminum is very less so application is limited where high strength is needed. Aluminum alloy which have greater potential for weight reduction as well as high strength to weight ratio have ability to overcome these …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 240–249 Read article
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An experimental study on flexural behavior of RC beams of Alccofine based engineered concrete infusing steel fibres
Abstract: The innovations in concrete being engineered to the specific requirements have found a new dimension under sustainability. Alccofine is a sustainable construction material derived from GGBS. The primary objective of the study is to explore the potential of Alccofine particles in varying proportions in combination with 0.5% steel fibers to uplift the flexural strength of the engineered concrete. As concrete is known to be a brittle material once hardened, exhibits …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 87–97 Read article
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A Review of Modifications of Cement Slurry Formulations for Carbon Dioxide Storage
Abstract: Climate action, which includes activities aimed at mitigating climate change or reducing its adverse impacts, is the thirteenth goal of the 2030 SDGs (Sustainable Development Goals). Tthe successful commercial deployment of CCS technology would heavily rely on the integrity of the cement sheath used to complete the wellbores at the CO₂ storage sites. It has been established that the cement sheath made from conventional ordinary Portland cement (OPC) is not …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 1–21 Read article
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Deep Cryogenic Treatment of Copper Chill Plates in Stir Casting of Al6061-Silicon Carbide Composites
Abstract: Aluminum-Silicon Carbide Metal Matrix Composites (Al/SiC MMCs) represent advanced materials created through the integration of aluminum matrices with silicon carbide particle reinforcement. These composites demonstrate superior characteristics compared to conventional aluminum alloys, establishing their relevance across diverse engineering applications. This experimental investigation focuses on developing composites using aluminum as the base matrix while incorporating SiC particles (40-50μm particle size) as reinforcing agents. The reinforcement content was systematically varied from 3 …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 116–126 Read article
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Functionally Graded Natural Fibre and SiC-reinforced Polymer Composite: Mechanical Properties
Abstract: Multifunctional materials, also called functionally graded materials (FGMs), are based on natural fibres or fillers and vary in composition and/or microstructure to control functional, structural, or thermal, properties. Functionally graded materials (FGMs) have been created for use in spacecraft, aircraft, and other engineering applications because they can withstand extremely high temperatures. Particle-reinforced FGMs, which make up the majority of FGMs, are made differently depending on their position. The mechanical and …
Published in Journal of Polymer & Composites · Vol. 11, Issue 4, 2023 · pp. 1–14 Read article
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Influence of Rheological and Physical Properties of Particles and Liquid media to compute Terminal Fall Velocity: A Review
Abstract: The hydrodynamic demeanor of falling particles and the liquid media in which they fall, supported by data analytics, is indispensable in the computation of the terminal falling rate. which is a critical concept in many civil engineering disciplines. The application of terminal settling velocity becomes vital to prevent the settling of microplastic particles (< 5 mm in size), several metal particles, polymers, etc.; especially those of irregular shape. Past research …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 28–40 Read article
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Numerical Study of Natural Convection Heat Transfer in Porous Particles Through Composite Filters
Abstract: The study of heat transmission through porous materials within the confines of reactor configurations stands as a pivotal realm of inquiry in the realms of engineering and the applied sciences, possessing wide-ranging applications spanning from soil mechanics to the refinement of heat exchange systems. Porous substances, distinguished by their interconnected voids or interstices, present an array of reactor forms that profoundly shape the flow of fluids and the conveyance of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 268–279 Read article
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Composite Behavior of Bagasse Ash Stabilized Expansive Soil with Sodium Benzophenone Under Curing Conditions
Abstract: The present investigation examines the development of a hybrid composite using Black Cotton (BC) soil, Bagasse Ash (BA), and Sodium Benzophenone (SBP) as performance-enhancing elements. Different ratios of BA, a silica-rich agro-industrial by-product, were added to improve pozzolanic reactivity and particle size distribution (0%, 6%, and 12%). SBP was added in the range of 0–0.6% as a compatibilizer in order to enhance interfacial adhesion, particle cohesivity and moisture-assisted deterioration resistance. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1134–1146 Read article
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Comprehensive Study on the Mechanical And Tribological Response of Waste Tyre Rubber–Natural Fiber Hybrid Epoxy Composites
Abstract: Research into the mechanical and tribological characteristics of Prosopis juliflora-fiber reinforced epoxy-matrix composites with recycled tyre rubber particles is the focus of this investigation. Making use of old tire rubber and bio-reinforcing with fibers from the common invasive plant Prosopis juliflora are the goals of the two-reinforcement technique. The end goal is to produce long-lasting, cost-effective engineered composite materials with improved performance. A constant epoxy resin matrix was used to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Development of a Durable Superhydrophobic EP/PDMS Coating Reinforced with Micro-CaCO₃ and Nano-ZnO for Enhanced Corrosion Protection and Multifunctional Performance on Carbon Steel
Abstract: Balancing exceptional multifunctional performance with mechanical robustness in micro-nano composite films remains a significant challenge for practical applications. In this work, a superhydrophobic coating reinforced with micro-CaCO₃ and nano-ZnO particles was fabricated through a versatile single-step brushing method. The optimized EP/PDMS@micro-CaCO₃/nano-ZnO coating achieved a water contact angle (WCA) of 173.54° ± 2.53° and a sliding angle (SA) of 1.50° ± 1.12°. Owing to its carefully engineered micro-nano hierarchical structure, the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 216–238 Read article
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Unveiling the Role of Lead Molecules in CADD: A Systematic Review
Abstract: The word "medicate plan" alludes to the objective creation of modern drugs. Arbitrary screening of engineered compounds, engineered of organically dynamic compounds based on actually happening drugs, amalgamation of basic analogs of actually happening lead particles, and usage of the bioisosteric hypothesis are a few of the strategies that have been utilized. As a result, the most recent drift in medicate plan is to either completely enhance a lead or …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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Kinematic Relations of Particle Motion using Polar Cylindrical Coordinates System: Applications in Robotics and AI
Abstract: This paper explores the motion of a particle in space using the cylindrical polar coordinate system. It presents the physics of particle motion by defining spatial positions in three-dimensional polar coordinates and examining the particle’s kinematics—namely its position, velocity, and acceleration—in vector form. These quantities are mathematically expressed as functions of time, accounting for the changing coordinates in radial, angular, and vertical directions. This coordinate system proves especially useful for …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 1, 2025 · pp. 12–16 Read article
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Investigation of Bio-Physical Interaction and Electrophoretic Properties of Fe3O4/DNA Nanocomposite and Colloids for Biomedical Application
Abstract: In recent years, research on magnetic nanoparticles has gained significant attention. The core concept behind their physics lies in their interaction with biomolecules such as hemoglobin, DNA, and RNA. This study examines the fundamental forces involved in these interactions, including van der Waals attractions, electrostatic repulsion, thermal effects, and magnetic coupling between nanoparticles and biological molecules. To describe these interactions quantitatively, parameters such as zeta potential, magnetic moment density, and …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 3, 2025 · pp. 20–32 Read article
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In-depth Evaluation of the CBR Method in Flexible Pavement Design
Abstract: The California Bearing Ratio (CBR) value of the subgrade is a crucial parameter utilized in the design of flexible pavements, as recommended by the Indian Roads Congress (IRC). The choice of materials used in constructing the pavement can significantly influence its overall design and performance. Pavements play an essential role in ensuring traffic flows smoothly, safely, and efficiently. Generally, pavements are categorized into two types: flexible and rigid. Flexible pavements …
Published in Trends in Transport Engineering and Applications · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
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Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article