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319 articles for “mono-”
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Preliminary In Silico Analysis of Choline Monooxygenase and Betaine Aldehyde Dehydrogenase from Suaeda monoica Forssk. and its Expression in E. coli.
Abstract: AbstractIn a tropical country like India, the yield of crop plants is majorly affected by soil salinity and drought. One of the strategies to address this problem is by introducing genes responsible for salinity/drought tolerance in crop plants. Such genes could be identified and isolated from mangrove plants, as they are known to have evolved certain physiological mechanisms to augment saline environments. One such mechanism is the accumulation of Glycine …
Published in Research and Reviews : Journal of Computational Biology · Vol. 9, Issue 1, 2020 · pp. 10–39 Read article
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Describing Microbial Growth Rate in Solid Suspended Media using Monod and Haldane Models
Abstract: This work details the procedure for curve fitting the Monod and Haldane’s growth models in for solid suspended media such as food waste; in order to determine their parameters for solid suspended media such as food waste. Seven different batch runs; each with initial substrate concentration were studied at constant temperature. A modified method was used to quantify the mass of microbes during the rection process and data obtained were …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 11, Issue 1, 2024 Read article
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Design and Pinch Analysis of Mono-Isopropyl Amine Production Process Using Aspen Plus and Aspen Energy Analyzer
Abstract: This paper presents the design of Mono-isopropyl amine production process. Process flow diagram is designed with Aspen Plus user interface. Mono-isopropyl amine obtained is of purity 100% and the designed plant is safe to environment with less emissions. After the design of the process pinch analysis is applied for the entire process by using Aspen Energy analyzer. From the extracted data using Aspen Energy Analyzer a HEN (Heat Exchanger Network) …
Published in Emerging Trends in Chemical Engineering · Vol. 1, Issue 3, 2014 · pp. 15–24 Read article
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Reactivity of Monochlorotetrakis2-Isopropylphenoxoniobium(V), [NbCl(OC6H4CH(CH3)2-2)4] towards Chelating Ligands
Abstract: The niobium(V) complexes with the formula [NbCl(OC₆H₄CH(CH₃)₂-2)₄] were successfully synthesized in high yields through the reaction of niobium pentachloride with four equivalent amounts of 2-isopropylphenol in carbon tetrachloride. The synthesized complexes were characterized and confirmed by elemental analysis, molar conductance measurements, infrared (IR) spectroscopy, ^1H and ^13C NMR spectroscopy, as well as mass spectrometric analysis. The spectroscopic studies have shown these to exhibit dimeric structures bridging through isopropylphenoxo groups. The …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 37–45 Read article
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A Forensic Study on Serum Leucine Aminopeptidase Activity Alteration in Carbon Monoxide Poisoning
Abstract: Background: Recently, Carbon Monoxide poisoning is diagnosed medicolegally depended on poison analytic chemistry and not in biochemical method. Methods: This essay was confirmed the activation change of LAP in Carbon Monoxide poisoning. The LAP activation level was higher than normal in a death with CO poisoning. Because of the Carbon Monoxide poisoning, patients were admitted to the hospital and were cured during a certain period of time. After that, the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 2, 2024 · pp. 71–75 Read article
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Seismic Performance of Mono-Support Building Equipped with Exoskeletons
Abstract: Seismic performance of the structure is one of the most crucial and important aspect of structural engineering. There have been many developments in the field of seismic resistance to enhance the behavior of the structures during seismically activated conditions. In this study the Seismic performance of buildings standing on singular columns have been studied. To enhance the dynamic behavior of the structures analyzed, the buildings were additionally equipped with steel …
Published in Journal of Structural Engineering and Management · Vol. 10, Issue 2, 2023 · pp. 13–22 Read article
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Effect of 2D-EBG Structure on Monopole Antenna Radiation and Analysis of Its Characteristics
Abstract: In this paper, we present a two dimensional electromagnetic (2D-EBG) square shaped mushroom structure placed between two monopole antennas. Two artificial properties of this 2D-EBG structure such as PMC and Band Reject Region are investigated here. The radiation characteristics of a monopole antenna over this, 2D-EBG structure is tested by considering two cases. In the first case monopole antenna is made to operate within band rejection region where as in …
Published in Journal of Microwave Engineering and Technologies · Vol. 2, Issue 2, 2015 · pp. 1–4 Read article
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Monoclonal Antibodies in Next Generation Animal Nutrition: Mapping Nutrient Immune Interaction Networks in Livestock Systems
Abstract: Sustainable livestock production is increasingly constrained by disease pressure, antimicrobial resistance, and declining feed efficiency under intensifying environmental stressors. Conventional nutritional strategies, while essential, remain insufficient to precisely regulate immune function and metabolic resilience. This review explores the emerging role of Monoclonal antibodies as advanced biologics in next generation animal nutrition, with a focus on mapping nutrient immune interaction networks in livestock systems. It synthesizes current knowledge on how nutrients …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Application of Monod and Finite Element Models for Groundwater Cleanup in the Niger Delta Area of Nigeria
Abstract: The Niger Delta region of Nigeria, known for its rich biodiversity and extensive oil and gas exploration activities, faces significant environmental degradation, including groundwater contamination. This study investigates the application of Monod kinetics and Finite Element Models (FEM) in the cleanup of groundwater contamination in the Niger Delta. Specifically, the research integrates Monod models to understand microbial degradation rates in contaminated aquifers and FEM to simulate the groundwater flow and …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 1, 2025 · pp. 39–47 Read article
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Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Rectangular Patch Monopole Antenna with Different Shaped Multiple Slots for Triple Band Frequency Applications
Abstract: In this paper a rectangular patch microstrip antenna with different shaped multiple slots behaves as a triple band monopole antenna. It is designed for 0.96031–1.0464, 1.3766–1.5797 and 2.1629–2.3708 GHz frequency bands. A rectangular patch monopole antenna with multiple slots, i.e., hexagonal slot and rectangular slot is fabricated on the glass epoxy (FR4 lossy) of dielectric substrate with relative permittivity (εr) of 4.4, thickness of 1.6 mm, loss tangent of 0.02 …
Published in Journal of Microwave Engineering and Technologies · Vol. 1, Issue 2, 2014 · pp. 17–24 Read article
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Hill Climbing Motorcycle with Extended Swing Arm and Mono Suspension
Abstract: The paper “Hill climbing motorcycle with extended swing arm and mono suspension” deals with the implementation of various parts for the advancement of the road motorcycle to hill climbing motorcycle. In recent years, hill climbing is considered as a sport in many abroad countries. No normal road motorcycle can be used for this purpose. i.e. it does not provide proper stability and control of the vehicle over steep hills. In …
Published in Recent Trends in Fluid Mechanics · Vol. 6, Issue 2, 2019 · pp. 19–27 Read article
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Compact Fork-shaped Monopole Antenna for Bluetooth, WLAN and Wi-MAX Applications
Abstract: This paper presents a fork-shaped monopole antenna (FSMA) with compact size. The proposed FSMA consisting a fork-shaped radiator and a partial ground plane with L-shaped and rectangular slits. The size of the proposed FSMA is 34 × 18 × 1.6 mm3 which is fed by 50Ω microstrip line. The L-shaped slit is introduced in the ground plane to enhance the bandwidth impedance of the proposed FSMA. The proposed antenna achieved …
Published in Trends in Opto-electro & Optical Communication Read article
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Mechanical & Tribological Characterization of Al2024-Alumina-Graphite Reinforced Monolithic and Hybrid Composites
Abstract: This work investigates the mechanical characteristics of Al2024-Al2O3-Graphite reinforced monolithic and hybrid composites fabricated by the stir casting method. Exploratory work involved the fabrication of monolithic composites with varying Al2O3 contents (5-8 wt%) and hybrid composites with the ratios of Al2O3 (2-6 wt%) and Graphite (1-3 wt%) in matrix Al2024. For improving their dispersion, preheated reinforcement particles were introduced in matrix alloy at controlled stirring rates. A homogeneous particle distribution …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 823–836 Read article
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Integrative Structural-Functional Genomics of Fc and Fab: Precision Models for Monoclonal Antibody Stability and Anti-Aggregation Engineering
Abstract: Monoclonal antibodies (mAbs) represent the cornerstone of biotherapeutics, yet aggregation propensity compromises up to 50% of candidates during development, driven by Fab hypervariability and Fc vulnerabilities.(1,2) This review integrates functional genomics from OAS (4B+ sequences)(5) and structural databases (SAbDab: 10K+ structures)(6) with machine learning models achieving R=0.97 for SAP prediction.(11) We dissect biophysical mechanisms, benchmark predictive tools (DeepSP, ESM2), and engineering strategies (YTE, FW mutations) that enhance Tm by 5-10°C …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable Therapeutics
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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A Quad-Element UWB-MIMO Triangular Monopole Antenna with Triple Band -Notch and High Isolation
Abstract: A quad-element UWB-MIMO triangular monopole antenna with triple notched bands and high isolation is proposed in this paper. The presented antenna consists of four triangular -shaped antenna elements, which are arranged in orthogonal orientation. This antenna is printed on low-cost FR-4 substrate with dielectric constant of 4.4 and its overall size is 50 × 50 × 1.6 mm3. Its operating frequency band is 2.97~11GHz. High isolation of 22dB between four …
Published in Journal of Microwave Engineering and Technologies · Vol. 10, Issue 2, 2023 · pp. 30–37 Read article
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Compact Fork-shaped Monopole Antenna for Bluetooth, WLAN and Wi-MAX Applications
Abstract: This paper presents a fork-shaped monopole antenna (FSMA) with compact size. The proposed FSMA consisting a fork-shaped radiator and a partial ground plane with L-shaped and rectangular slits. The size of the proposed FSMA is 34×18×1.6 mm3 which is fed by 50Ω microstrip line. The L-shaped slit is introduced in the ground plane to enhance the bandwidth impedance of the proposed FSMA. The proposed antenna achieved 10dB return loss bandwidth …
Published in Trends in Opto-electro & Optical Communication · Vol. 11, Issue 1, 2021 · pp. 1–6 Read article