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18 articles for “liver cells and kidney cells”
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Computational Analysis of Epithelial Stratum and Physical Condition of Human Kidney Cells and Liver Cells Using Non Destructive Testing Technique by Scanning Acoustic Microscope
Abstract: The present work deals with the methodology governing scanning acoustic microscope (SAM) for non-destructive testing of biological samples (liver cells and kidney cells). Acoustic microscopy was performed on liver cells and kidney cells for measuring their thickness and also to determine their shapes. This technique was also used for evaluation of internal damage to cells. SAM images were taken for further qualitative and quantitative assessments. Using the quantitative data obtained …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 1, 2015 · pp. 1–4 Read article
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A Review of basic Concept of Specific Drug Delivery System
Abstract: ABSTRACTThis review focus going on targeted drug delivery via Nanoparticles as a Special composition that couple a receptor site to a Nanosized , drug-loaded transporter as a budding means to get improved effectiveness of a drug at the site of significance. The conception of targeted drugs is not new, but since to 1906 while Ehrlich initial postulate the ‘magic bullet’. therefore is must to build up a appropriate drug system …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 3, 2022 · pp. 21–26 Read article
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Effects of Chlorpyrifos as Inducer for Oxidative Stress in Liver, Kidney and Spleen of Freshwater Fish, Pseudetroplus maculatus (Bloch, 1795)
Abstract: Chlorpyrifos is one of the most common organophosphate insecticides found abundantly in freshwater ecosystems and has been detected in agricultural and fishery products worldwide. The study focused to determine the effect of chlorpyrifos on the induction of oxidative stress in freshwater fish Pseudetroplus maculatus. Fish were exposed to sublethal concentrations (0.661 and 1.32 μg/l) of chlorpyrifos for 15 and 30 days. Activities of antioxidant enzymes and the levels of hydrogen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 20–29 Read article
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Treatment of Korean Panax Ginseng against Cisplatin-Induced Toxicity in Rats Haematological and Histological Examination of Liver, Spleen and Kidney
Abstract: Vital goal of all anti-cancer therapies are to prevent the incidence of side effects either through more selective therapeutic methodology that target only neoplastic cells or through the use of complementary or alternative medicine. Present study investigated the effects of Panax ginseng (PG) on cisplatin-induced haematological and histopathological (liver, kidney and spleen) changes in rats. Rats were administered with PG (25, 50, 100 mg/kg) before or after an intraperitoneal injection …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 35–39 Read article
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SGOT (Serum Glutamic Oxaloacetic Transaminase)—Its Role (A Review Article)
Abstract: Aspartate transaminase (AST) is an important liver enzyme which catalyses reversible transfer of an alpha amino group between aspartate and glutamate. It has an important role in amino acid metabolism. AST is predominantly found in the liver, skeletal muscle, kidneys, brain and red blood cells. AST is measured as a part of diagnostic liver function test, but AST reflects pathology in organs other than liver. Elevation in AST is found …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 3, 2019 · pp. 1–5 Read article
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Assessment of Arsenic in Groundwater and Surface Water Sources of Gorakhpur District in Uttar Pradesh (India)
Abstract: This study was conducted in 19 blocks and 4 surface water of Gorakhpur district to assess the arsenic content. The study was carried out in the month of February-March, 2021. The result was compared with IS: 10500:2012 and WHO. The increased arsenic content in the water possess serious health issues in humans. The acute health issues being pigmentation on skin and damage to red blood cells. Prolonged exposure leads to …
Published in Journal of Water Pollution & Purification Research · pp. 1–9 Read article
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Unusual Distant Metastasis in Buccal Squamous Cell Carcinoma: A Case Report
Abstract: Head and neck squamous cell carcinomas (SCC) are known to have high loco regional recurrence with distant mets being rare. However, distant metastasis are showing an increasing trend due to the improved locoregional control rates achieved with surgery and radiotherapy. The usual sites of distant failure are lung, liver, bone, adrenal, heart and kidney. Here is presented a case of buccal SCC presenting with unusual distant soft tissue mets after …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 3, Issue 2, 2014 · pp. 15–17 Read article
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Histotoxicity of Acid Orange 7 on organs of Fresh water fish Labeo rohita
Abstract: The present paper reports the histotoxic effects of Acid Orange 7, an azo dye on the tissues viz. gill, kidney and liver in major carp, Labeo rohita, fingerlings. The sublethal concentrations of the dye are responsible for the histopathological alterations in the target tissues. In the gills hyperplasia, epithelial lifting, hooked secondary gill lamellae, haemorrhage in the primary gill lamellae and erosion of secondary gill lamellae were seen. The kidney …
Published in Research and Reviews: A Journal of Toxicology · Vol. 1, Issue 1-3, 2011 · pp. 45–54 Read article
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Mirabilis Jalapa Flower Extract as Natural Food Dye and Green Cellular Delivery of Nanoparticles
Abstract: Use of artificial colouring agents in sweets and packed food has become a common scenario now a day, which pose serious consequences in consumers especially children. Various studies around the globe reported the serious health hazards of artificial food dyes which include organ damage of liver, kidney and lungs thereby affecting metabolic enzymes, serum creatine and urea levels and brain damage resulting in neurotoxicity and even behavioural deficits in children. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 2, 2023 · pp. 27–34 Read article
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Review on Histological and Functional Effect of Alcohol on Liver and Kidney
Abstract: Alcohol consumption represents the third largest risk factor for disease burden in most countries of the world. The purpose of this review is to give a comprehensive report of the existing data on the potential adverse effects of alcohol on liver and kidney toxicity. We used 82 different published materials for the compilation of this review article. The Google search engine was used for accessing published materials from databases like …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 2, 2018 · pp. 49–62 Read article
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Protective Effect of Epigallocatechin Gallate (EGCG) on Sodium Fluoride (NaF) Induced Changes in Histology of Selected Organs in Rats
Abstract: Histopathology is the microscopical examination of biological tissues to observe the appearance of diseased cells and tissues in very fine detail. The present study, has been designed to evaluate the effects of oral administration of Sodium Fluoride (NaF) 25 mg/kg/bw (orally), NaF with EGCG (40 mg/kg/bw) daily for four weeks on histological alterations, if any on heart, liver, kidney and testes of rats. Rats were weighed about 160–180 g. NaF …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 1, 2013 · pp. 20–26 Read article
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Review on Histological Effect of Lead on Liver and Kidney
Abstract: Our environment can be polluted by environmental toxins which are chemicals and other materials produced largely from industry and its products. There are large numbers of environmental toxicants which are potentially harmful to health. These large numbers of environmental toxicants can be divided into three major categories (heavy metals, air pollutants, and pesticides) and they are commonly studied environmental toxicants. Environmental toxins can be entered into the body by various …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 8–29 Read article
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Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
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Cadmium Accumulation in Different Tissues and DNA Content Alteration in Cat Fish (Clarias batrachus) Exposed to Lethal Concentration of Cadmium
Abstract: In the present study, the acute toxicity experiment was conducted to evaluate LC50 of Cadmium chloride (CdCl2) on Clarias batrachus which was found to be 450 ppm for 96 h. Clarias batrachus (average length of 8.5 ± 0.4 cm and the average weight of 13.5 ± 0.393 g) was exposed to sub-lethal concentration (140 ppm) and lethal (450 ppm) concentrations of Cd for 14 days. The Cd accumulation in tissues …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 1–8 Read article
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Study on safety of Unani pharmacopeial formulation Qurs Kusta Khabas- al- Hadeed and Habb- e-Marwareed in cases of Sailanur Reham (Leucorrhoea)
Abstract: Leucorrhoea is nothing but excessive vaginal discharge, it is common gynaecological complaint . Main objective of the present study was to study safety parameter of Unani formulation Qurs-e- Kusta Khubs al Hadeed and Habb-e-Marwarweed in cases of Sayalan-al-Rahim (Leucorrhoea).Study was jointly conducted in the laboratory at Regional Research Institute of Unani Medicine, New Delhi. For this 56 females patientsin the age group of 18-60 years presenting sign and symptom with …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 1, 2023 · pp. 1–7 Read article
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Arsenic as a Cause of Cancer
Abstract: Inorganic Arsenic (iAs) is a pervasive and ubiquitous environmental toxin that has created world-wide human health problems. Populations exposed to high concentrations of arsenic-contaminated drinking water suffer serious health consequences ranging from acute toxicities to development of malignancies, including alarming cancer incidence and death rates. Epidemiologic studies have shown a relationship between chronic arsenic exposure and disease of the skin, lung, urinary bladder, and conceivably liver, kidney, and prostate in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 3, 2016 · pp. 8–21 Read article
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Effect of Unani Pharmacopeial Formulation Damavi on Iron Profile in Cases of Anaemia
Abstract: Anaemia is decrease in red blood cells or haemoglobin in blood; its frequency is around 2.36 billion i.e. 33% in 2015. Important symptoms associated include paleness of skin, weakness, shortness of breath, poor ability to exercise, etc. Many Unani formulations are used for treating anaemia but in this study, Tab. Damavi was used to see its effect on iron profile. This study was carried out at Regional Research Institute of …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 1, 2022 · pp. 9–15 Read article
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Cadmium Toxicity: Oxidative Stress and Organ Dysfunction
Abstract: Due to continued anthropogenic mobilization, cadmium accumulation in the environment causes various health problems because of its diverse toxic effects, extremely lingering biological half life (20–30 years), low rate of excretion from the body and storage predominantly in soft tissue primarily liver and kidney. Cadmium is known to have numerous noxious effects, including nephrotoxicity, hepatoxicity, osteoporosis, cardiovascular toxicity, lung toxicity, and reproductive toxicity. The biologically significant ionic form of cadmium, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 2, 2014 · pp. 14–31 Read article