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67 articles for “in vitro techniques”
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Improvement of Crop Plants through in vitro Techniques
Abstract: There has been a great demand for high-yielding, disease-free planting stock for agricultural, forestry, plantation and horticulture crops with improved quality. In vitro tissue culture techniques has emerged as a viable tool for the improvement of crops. The various in vitro techniques utilized for crop improvement includes: micropropagation which helps in large scale production, meristem culture which can effectively remove pathogens from plants, embryo culture can overcome the post-zygotic failure …
Published in Research & Reviews : Journal of Botany · Vol. 11, Issue 2, 2022 · pp. 12–24 Read article
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Enhancement of Some Pharmaceutically Important Secondary Metabolites By in vitro Techniques
Abstract: AbstractSecondary metabolites are economically important as drugs, dyes and pigments, pesticides, and food additives. The evolving commercial importance of secondary metabolites has in recent years resulted in a great interest in mechanism of secondary metabolism, especially in the production of bioactive plant metabolites by means of tissue culture technology. Plant cell and tissue culture technologies can be established for both multiplication and extraction of secondary metabolites. Strain improvement, methods for …
Published in Research & Reviews : Journal of Herbal Science · Vol. 3, Issue 1, 2014 · pp. 6–14 Read article
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A Rapid in vitro Propagation of Bambusa balcooa by Plant Tissue Culture Technique
Abstract: Bambusa balcooa is a common plant grown in Bihar, Orissa, Jharkhand and Uttarakhand states of India having good cultural importance. The present experimentation on nodal explants of B. balcooa on MS media supplement under particular culture conditions have shown shunted growth in 30 days. Shoot tip explants of B. balcooa seedlings produced multiple shoots on MS medium supplemented with different plant growth regulators (PGRs) individually and in combination. Shoot tip …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 8, Issue 1, 2018 · pp. 27–31 Read article
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Comparative Evaluation of the Effect of Adhesive Restorative Techniques on the Reinforcement of Simulated Immature Permanent Teeth: An in Vitro Study
Abstract: The aim of the study was to compare the reinforcement effect of 3 different adhesive restorative techniques on simulated immature maxillary central incisors after apexification. A total of 30 simulated immature permanent maxillary central incisors were randomly assigned into 3 groups (n=10), according to the reinforcing technique used: Group 1: Nanohybrid composite. (Tetric N-Ceram Ivoclar Vivadent), Group 2: Short-fiber reinforced composite (everX posterior GC EUROPE) extended 3mm below CEJ, covered …
Published in Journal of Polymer & Composites · Vol. 10, Issue 3, 2022 · pp. 69–75 Read article
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In vitro Axillary Bud Proliferation and Direct Organogenesis of Aristolochia tagala cham.: A Rare Medicinal Plant
Abstract: AbstractAn efficient protocol for axillary bud proliferation and direct organogenesis has been developed in Aristolochia tagala Cham. through in vitro propagation technique. Nodal segments and shoot tips were cultured on Murashige and Skoog’s media (MS media) supplemented with various concentrations of growth hormones. MS media fortified with BAP 1 mg/L and half-strength MS media with IBA 2 mg/L were found to be the best for inducing shoots and roots respectively.Keywords: …
Published in Research & Reviews : Journal of Botany · Vol. 4, Issue 2, 2015 · pp. 21–27 Read article
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A Review On Evaluation Of Abiotic Stress Signals On Production Of Gymnemic Acid In In Vitro Cultures Of Gymnema Sylvestre R.Br
Abstract: The demand and market value of medicinal plants increases day by day. The raw materials for herbal medicine industry came from wild collections. Due to intense demand, natural populations are under stress and many species of medicinal plants became vulnerable. To overcome the issue new methods to conserve and propagate medicinal plants on large scale. In vitro propagation techniques are effective for the multiplication and conservation. Advantages like availability of …
Published in Research & Reviews : Journal of Botany · Vol. 12, Issue 2, 2023 · pp. 28–35 Read article
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Development and Fabrication of Biohydrogel for Targeted Delivery of Delafloxacin for Bacterial Skin Infections
Abstract: The escalating challenge of bacterial resistance necessitates innovative drug delivery systems to enhance the efficacy of antibiotics. This study focuses on the development and optimization of a biohydrogel formulation for the targeted delivery of Delafloxacin, aiming to improve its therapeutic outcomes against resistant bacterial strains. Utilizing a 3² factorial design, biohydrogel formulations incorporating Poly(N-isopropylacrylamide) (PNIPAM) and Genipin were synthesized. The optimization process was guided by Design Expert software, focusing on …
Published in Research & Reviews: A Journal of Drug Design & Discovery Read article
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Carboxymethyl Cellulose-Based Spray-Dried Microspheres: Recent Advances and Applications in Targeted Drug Delivery Systems
Abstract: Microspheres are spherical particles ranging from 1 to 1000 μm, made from natural or synthetic polymers and inorganic materials. Their structure allows precise drug delivery, improving targeted release and minimizing off-target effects. Natural polymers such as starch, chitosan, and alginate are favored for their biodegradability, adhesion, and compatibility, enhancing mucosal interaction and residence time. Microspheres are widely used in site-specific drug delivery, gene therapy, and vaccine administration, improving immunogenicity, extending …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 251–268 Read article
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Plant Mediated Metal Nanoparticles for Wound Healing Activity – A Review
Abstract: The development of nanotechnology, which is playing a part in every discipline subject, is a recent achievement in the science and technology fields. Modern nanotechnology places a high priority on environmentally friendly methods of producing metal nanoparticles. Utilizing plant extract is cost-effective, environmentally friendly, and has less negative side effects. The development of the new discipline of "Nano medicine" is due to the therapy of various chronic non-communicable diseases with …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 1, 2023 · pp. 1–11 Read article
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Recent Trends in Ocular Drug Delivery: Challenges and Approaches
Abstract: Drug topically regulation can be accessed most easily in the eye. When given topically as eye drops, medication ocular bioavailability is quite low. Drug entry into specific ocular locations is complicated by the complex anatomy and physiology of the human eye. Research has long been interested in the topical administration of successful treatments. To provide a suitable ocular penetration and extend the duration of drug residence is their challenging task. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 22–38 Read article
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Characterization of Synthesized Heterocyclic Oxadiazole Derivatives Using Mass, UV, IR, and NMR Spectroscopy, Among other Spectroscopic Techniques: Review
Abstract: The current study synthesized and assessed 3-heteroarylazo 4-hydroxy coumarin derivatives' initial antibacterial activities in vitro against four distinct pathogenic bacterial strains, including Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli, and Staphylococcus aureus. Ampicillin, a common medication, was used to compare each compound's antibacterial properties. UV, IR, 1H NMR, mass spectroscopy, and X-ray diffraction examinations were used to analyze the compounds. By using UV–vis spectra, the solute-chromic behavior of these compounds was …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 1, 2023 · pp. 28–33 Read article
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Advancements in Solubility Enhancement Through Liquisolid Compact Technology: A Comprehensive Review
Abstract: The study examines Liquisolid Compact Technology as an innovative approach for improving the bioavailability and solubility of drugs that are poorly soluble in water. Liquisolid systems, comprising solid carriers and liquid drugs, offer advantages such as improved drug release and bioavailability, reduced manufacturing costs, and controlled drug delivery. The technique involves dissolving or suspending the drug in non-volatile solvents, adding carrier materials, super disintegrants, and coating materials, and then compressing …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 25–34 Read article
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Production and Characterization of Cardanol Based Schiff Complexes and their Biological Significance
Abstract: Synthesis and analysis of cardanol consisted Schiff base ligand along with its complexes such as Cu, Co and Ni are considered as a novel tetradentate cardanol contained Schiff base ligand molecules for various biological effects. It is prepared by the condensation reaction of 2-aminophenol and di-α formylmethoxybis (3-pentadecenyl phenyl) methane which is termed as DFMPM in the molar ratio of 2:1. The characterization of the experimental compounds is done with …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 2, 2019 · pp. 19–24 Read article
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Self-Evaluation of CO2 Incubator before In-Vitro Handling of Gametes and Embryos
Abstract: AbstractART (Assisted Reproductive Technologies) is known as the technologies/techniques used for the treatment of Infertility. ART involves different types of newly and advanced techniques such as ICSI (Intra-Cytoplasmic Sperm Injection), MESA (Microsurgical Epididymis Sperm Aspiration), PESA (Percutaneous Epididymal Sperm Aspiration),TESA (Testicular Sperm Aspiration), IMSI (Intra Morphologically selected sperm injection), GIFT (Gamete Intra-fallopian Transfer), ZIFT (Zygote Intra-fallopian Transfer) and Assisted hatching. The self-evaluation and maintenance of all equipment used in the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 2, 2020 · pp. 7–11 Read article
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Formulation Development and In Vitro Evaluations of Trimetazidine and Clopidogrel Bilayered Tablets
Abstract: The Bilayered tablets consisting of Trimetazidine SR as well as Clopidogrel IR were efficiently prepared by damp granulation technique as well as straight compression approach specifically. The prepared powdered mix (SR) were also preserved the physiochemical residential or commercial properties of tablet computers such as thickness, firmness, weight variant, friability and drug material. The enhanced formula consists of the average thickness of 3.1 ± 0.034, average firmness of 4.2 ± …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 3, 2023 · pp. 29–40 Read article
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In vitro Cultivation of Trifolium Alexandrium L. as a Forage Crop for Sustainability of Pastoral Ecosystem
Abstract: Trifolium alexandrium L., commonly known as Berseem or clover, is an important leguminous winter fodder crop. In comparison to other legumes and grasses, clover provides forage with high nutritional value and quality. Hence, introduction of Berseem (clover) in existing pastoral ecosystem can provide value-added forage that can result in an increased level of animal production and simultaneously enhance stocking rates. Tissue culture is a technique through which we are able …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 3, Issue 2, 2013 · pp. 6–11 Read article
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Food Packaging Chemicals and Human Health: Molecular Toxicity, Exposure Pathways, and Regulatory Perspectives
Abstract: Food packaging plays a vital role in preserving food quality, extending shelf life, and ensuring safe transportation. However, increasing evidence indicates that chemicals from packaging materials can migrate into food during processing, storage, and consumption, resulting in chronic human exposure. Several food packaging chemicals, including bisphenols, phthalates, per- and polyfluoroalkyl substances (PFAS), styrene, heavy metals, and non-intentionally added substances (NIAS), have emerged as important xenobiotics due to their potential adverse …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 Read article
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Formulation Development and Evaluation of Floating Tablets of Venlafaxine Hydrochloride
Abstract: The aim of the present study was to formulate and evaluate gastroretentive floating tablets of an antidepressant drug, Venlafaxine HCl. The matrix tablets of Venlafaxine hydrochloride were prepared by employing low viscosity grade hydrophilic polymer HPMC E15LV in combination with any one of the high viscosity grades of HPMC (K4M, K15M, and K100M) as swelling polymers. Sodium bicarbonate was employed as gas generating agent. The tablets were formulated using direct …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 1, 2015 · pp. 7–15 Read article
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Fabrication and Assessment of Gallic Acid as Novel Drug Carrier
Abstract: Objective: The purpose of the current investigation is to develop and evaluate the polymer-based microspheres to overcome the issues of frequent dosing and high first pass metabolism. Materials and Methods: Gallic acid loaded microsphere were prepared by solvent evaporation technique and the microspheres were evaluated for drug entrapment efficiency, drug loading efficacy, particle size, In-vitro drug release, surface morphology and FTIR spectroscopy studies. Results: The percentage yield, drug entrapment and …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 5–10 Read article
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Enhancement of Bioavailability of Clopidogrel Using Different Solubility Enhancement Techniques
Abstract: Bioavailability is the key determinant of a drug for its therapeutic effectiveness, which in turn depends upon the solubility of that drug in gastro intestinal fluid. Clopidogrel is a BCS class II drug. Drugs of this category have low solubility and high permeability, so their bioavailability is less. This can be overcome by doing pharmaceutic modifications on it. In the present study, three different modifications, namely, complexation, solvent deposition and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 2, 2016 · pp. 25–39 Read article