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24 articles for “fatty acid oxidation”
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Engineering Fatty Acid Oxidation Pathway for the Production of Yeast-based Monomers
Abstract: Yeast-based monomers have a wider application in many fields and used for polymer production. Yeast system is used to improve the production of such valuable monomers by exploiting the metabolic pathways of interest. Alkane-utilizing yeasts mediate the fatty acid catabolism inside the peroxisomes primarily through beta (β) oxidation pathway, which breaks up the long chain fatty acids resulting in the synthesis of energy producing molecules. This allows the reduced inflow …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 3, Issue 1, 2013 · pp. 6–9 Read article
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The Role of Pyruvate Dehydrogenase in Non-Alcoholic Fatty Liver Disease: Therapeutic Insights and Future Directions
Abstract: Non-alcoholic fatty liver disorders (NAFLD) are defined by the accumulation of excess fat in the liver that has no other cause, such as drinking alcohol. Pyruvate dehydrogenase has been established as an alternative treatment for this disorder. NAFLD pathogenesis is complex and includes oxidative stress inflammatory processes and mitochondrial dysfunction. Impaired liver fatty acid oxidation and glucose oxidation are significant individuals in developing NAFLD, and strategies to reverse these defects …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 44–51 Read article
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Effect of Snehpana (Lipid Based Drug Delivery System) with Shatpala Ghrit in Non-Alcholic Fatty Liver Diseases
Abstract: Among all the Drug Delivery Systems, Snehpana (~Lipid Based Drug Delivery System) is being widely used because this facilitates uniform distribution and absorption of fat and water-soluble chemical constituents. Due to their effective size-dependent properties and challenges related to the solubility and bioavailability of water-soluble drugs, this system holds a significant advantage. Numerous studies have highlighted the potential of lipid-based formulations in managing chronic and life-threatening diseases. Shatpala ghrit (SG) …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 1, 2025 · pp. 1–11 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
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Sustainable Production of Halal Butter from Mango Kernel Oil: Extraction, Characterization and Functional Evaluation
Abstract: Mango kernel oil (MKO) is a mango processing by-product and is increasingly of interest in food use because of its appropriate fat content. The growing demand of the halal and plant-based alternatives of butter points to the necessity of the sustainable non-dairy sources of fat. Mango kernel oil butter has good physicochemical properties such as a good balance of fatty acids, good oxidative stability, and the right level of moisture, …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 2, 2026 · pp. 12–21 Read article
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Integrative Network Biology Analysis of GSE6011 Uncovers Molecular Signatures in Duchenne Muscular Dystrophy
Abstract: Duchenne muscular dystrophy (DMD) is a rare, severe neuromuscular disorder demonstrated by progressive skeletal muscle deterioration and premature mortality. Despite advances in supportive care, no definitive cure exists, highlighting the need to explore novel molecular targets. The current study aimed to uncover key dysregulated genes and molecular pathways in DMD through a dataset-specific network biology approach. Publicly available microarray data (GSE6011) from DMD quadriceps muscle biopsies of 22 patients and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 36–48 Read article
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Production of Biodiesel from Vegetable (Soybean) Oil
Abstract: AbstractWe are living in a high time where we have to keep ourselves safe from the adverse effect pollution have on our nature, and in turn, on us. We see nowadays a very huge extent of pollution, and deaths this pollution and activities related to it causing. It is the need of the hour where we must opt for an alternative which is low on the pollution, and subsequently on …
Published in Journal of Offshore Structure and Technology · Vol. 5, Issue 1, 2018 · pp. 23–25 Read article
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Rapid Post-uterine Involution in Dairy Cows: Mechanisms, Dietary Strategies, and Impact on Postpartum Recovery
Abstract: The postpartum period in dairy cows is critical for reproductive success, with uterine involution playing a central role in returning the reproductive tract to its pre-pregnancy state. Rapid uterine involution is essential for improving reproductive performance and minimizing the risk of postpartum complications. This review explores the nutritional mechanisms that influence uterine involution, focusing on key dietary strategies to promote tissue repair and recovery. We examine the role of energy, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Modified Milk Fat and Its Applications in Food Products
Abstract: Natural fats have complex composition as they are composed of several fatty acids present primarily as triacylglycerols, which give fat highly diverse functional and nutritional properties. This complexity of fat provides opportunities for modifying themselves for different applications. The negative nutritional and physical image of the fat, especially certain saturated long chain fatty acids, trans-fats, cholesterol as well as poor spreadability and oxidative susceptibility has driven the development of technologies …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 2, Issue 3, 2013 · pp. 16–24 Read article
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Evaluation Of Anti Obesity Activity Of Citrus Sinensis & Citrus Limon By High Fat Diet Induced Model Using Danio Rerio
Abstract: Obesity, defined by the World Health Organization (WHO) as an abnormal or excessive fat accumulation that may impair health, is becoming one of the greatest challenges to global health in this millennium, with more than 300 million men and nearly 450 million women obese globally in 2018. Obesity turns into serious problem globally. Zebrafish model can be used extensively for drug screening due to its low maintenance cost, comparatively short …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 24–31 Read article
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Comparative Analysis of Natural vs. Synthetic Antioxidant during Deep-Fat Frying of Potato Chips
Abstract: The aim of this study was the comparative analysis of natural antioxidant derived from rosemary extract, mixed tocopherol, alpha tocopherol, Ascorbyl Palmitate with synthetic antioxidant (TBHQ) during deep fat frying. Palm oil with tertiary butylhydroquinone (TBHQ), a synthetic antioxidant, and palm oil without any added antioxidant were used as positive controls. Thermo-oxidative transformations were measured according to various physical and chemical parameters. Total polar compounds (TPC), free fatty acids (FFA), …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 4, Issue 2, 2015 · pp. 1–12 Read article
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Nutrient Sensing and Microbiota Crosstalk: Driving Determinants Shaping Metabolic Stability and Adaptive Physiology for Animal Health
Abstract: Nutrient sensing is a fundamental cellular process that enables animals to adapt to fluctuating dietary inputs while maintaining metabolic homeostasis and health. Recent advances reveal that the gut microbiota functions as an active metabolic partner, producing bioactive metabolites that directly influence host nutrient-sensing pathways and downstream cellular responses. This review synthesizes current knowledge on the integration of key signalling networks, including adenosine monophosphate activated protein kinase (AMPK), mechanistic target of …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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A Review on Cucurbita
Abstract: Cucurbita species is a good nutritional vegetable species and belongs to cucurbitaceae family. It is commonly grown throughout the world. It’s appearance is of green and yellowish-orange color. It contains so many nutritional values like proteins, fatty acids, carbohydrates and phytochemical constituents like phenolic compounds, flavonoids, tannins, etc. It shows so many pharmacological activities like anti-oxidant, anti-inflammatory, anti-cancer, anti-ulcer, anti-diabetic activities, etc.Keywords: Pumpkin, phytochemicals, anti-diabetic, nutrition, gallic acidCite this ArticleAman …
Published in Research & Reviews : Journal of Botany · Vol. 7, Issue 3, 2018 · pp. 15–16 Read article
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Garcinia cambogia Use of Weight Loss and Hepatotoxicity: A Review
Abstract: A complex disorder of hunger control and energy metabolism driven by certain biological variables is obesity. This study aims to evaluate the applications of Garcinia cambogia products for appetite suppression and fat burning. This little fruit, which looks a lot like a pumpkin, is marketed and used most frequently these days as a weight-loss supplement. Research has demonstrated that the fruit rind's main organic acid component, (−)-hydroxycitric acid (HCA), and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 08–14 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Nutrition Induced Remodeling Dynamics of Cell Membranes: Implications for Performance, Health, and Welfare Issues in Food Animals
Abstract: Cell membranes represent dynamic structural and functional platforms that integrate nutritional signals with cellular metabolism, immune competence, and physiological adaptation in food animals. Beyond their classical role as selective barriers, membranes actively regulate nutrient transport, signal transduction, and bioenergetics through highly responsive lipid and protein networks. Dietary components, particularly fatty acids, vitamins, minerals, amino acids, and bioactive compounds, critically influence membrane composition, fluidity, and stability, thereby shaping cellular function and …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 25–37 Read article
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Nutrient-Mediated Activation of Cellular Signaling Pathways: Mechanistic Insights into Attenuation of Toxin Induced Inflammation in Food Animals
Abstract: Dietary and environmental toxins remain a persistent challenge in food animal production, where subclinical and clinical inflammation compromises health, productivity, and food safety. Toxin induced inflammation is driven by oxidative stress, mitochondrial dysfunction, and dysregulated immune signaling, resulting in impaired metabolic efficiency and increased disease susceptibility. Recent advances in nutritional science have revealed that nutrients act not only as substrates for growth but also as signaling molecules capable of modulating …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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A Review on Pharmacological Activities of Oldenlandia Auricularia
Abstract: Oldenlandia auricularia is a medicinal plant, which is originated from South India, Australia, Malaysia, Philippines and Sri Lanka. It also grows in open forest and shrubs. The plant belongs to the Rubiaceae family. The species comprises of around 1,300 varieties. There are several chemical compounds in the plant that have distinct pharmacological characteristics. Alkaloids, anthroquinone, iridoids, sugars, glycosides, coumarin, fatty acids, flavonoids and phenolic compounds are among the phytochemicals found …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 1, 2022 · pp. 11–18 Read article