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59 articles for “computer aided design”
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An Extensive Analysis of Computer-Aided Drug Design for Novel Psychotropic and Neurological Substances
Abstract: A comprehensive review of the use of computer-aided drug design (CADD) in the creation of innovative neurologic and neuropsychiatric medications is given in this article. It discusses the challenges in traditional drug discovery approaches and highlights the role of computational methods in accelerating the identification and optimization of drug candidates targeting psychiatric and neurological disorders. The method of finding new drugs has been completely transformed by Computer-Aided Drug Design (CADD), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
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Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
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Analysis of Bioinformatics Software Applied in Computer-Aided Drug Design
Abstract: The integration of bioinformatic tools with computational methods has revolutionized the field of Computer-aided Drug Design (CADD), enabling researchers to expedite the discovery and optimization of new therapeutics. This review provides an in-depth analysis of the bioinformatic tools utilized in CADD, encompassing molecular docking, molecular dynamics simulation, virtual screening, homology modelling, and molecular visualization. We go over the tenets, approaches, and uses of these instruments, emphasizing their value in expediting …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 1–10 Read article
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Review on Computer-Aided Drug Design in RAS Inhibitor Discovery
Abstract: This review explores the utilization of computer-aided drug design (CADD) methodologies in the discovery of inhibitors targeting the RAS pathway, a pivotal signaling cascade implicated in various cancers. Through an extensive examination of computational tools, methodologies, challenges, and recent advancements, this review aims to provide insights into the role of CADD in accelerating RAS inhibitor discovery. The discovery of effective inhibitors targeting the RAS pathway is of paramount importance in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 7–14 Read article
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Modern Computer-aided Drug Design Methods: A Review
Abstract: Computer-aided drug design (CADD) has emerged as a crucial tool in the drug discovery process, offering a time-efficient and cost-effective approach to identifying potential drug candidates. This review aims to provide an overview of modern CADD methods, including high-throughput screening (HTS), structure-based drug design (SBDD), ligand-based drug design (LBDD), structure-based virtual screening (SBVS), and ligand-based virtual screening (LBVS). We discuss the basic principles, applicability, and limitations of each method, highlighting …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 14–20 Read article
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A Review on Anesthetic Drug Discovery with Computer Aided Drug Design
Abstract: In contemporary medicine, anaesthesia is essential for enabling surgical procedures, pain control, and patient comfort. Finding and creating safe and efficient anaesthetics is crucial to enhancing patient outcomes and developing the medical field. In this review, we provide a comprehensive overview of anesthetic drug discovery with a focus on the integration of computer-aided drug design (CADD) methodologies. Beginning with an exploration of anesthesia mechanisms and targets, we delve into the …
Published in International Journal of Antibiotics Read article
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Ligand Based Drug Virtual Screening in Computer Aided Drug Design: A Review
Abstract: Computer-Aided Drug Design (CADD) has revolutionized the drug discovery process by providing efficient and cost-effective methods for identifying potential drug candidates. Within CADD, ligandbased virtual screening techniques play a pivotal role in the early stages of drug discovery. This review provides a comprehensive overview of ligand-based drug virtual screening, focusing on its principles, applications, challenges, and future directions. Fundamentals of ligand-based virtual screening, including pharmacophore-based methods, similarity searching, and machine …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 1–8 Read article
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Computer Aided Drug Designing for Targeted Drug Delivery Systems
Abstract: The discovery and development of a contemporary sedate is widely acknowledged as an extremely difficult task that requires significant resources and effort. Therefore, computer-aided medication design techniques are widely utilized today to increase the productivity of the drug discovery and development process. Among structure-based and ligand-based drug design approaches, both recognized for their efficiency in drug discovery and development, various CADD (Computer-Aided Drug Design) techniques are evaluated based on specific …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 34–41 Read article
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Electronic Design Technology: From Circuits to Smart Systems
Abstract: Electronic Design Technology has changed a lot over the years. It has gone from making simple circuits to making smart, complicated systems that run modern life. This article looks at how electronic design methods have changed over time, focusing on important improvements in tools, materials, and integrated systems. It looks at how new technologies like computer-aided design (CAD), embedded systems, and automation have made product creation faster, more accurate, and …
Published in Journal of Electronic Design Technology · Vol. 17, Issue 1, 2026 · pp. 25–36 Read article
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Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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Computer-Aided Drug Design on Tuberculosis
Abstract: Currently, India's Directly Observed Treatment Short Course (DOTS) program is the world's largest and fastest-growing initiative for treating medical patients, second only in terms of population coverage. The main obstacles to TB control in India are inadequate primary healthcare in rural regions of many states, unregulated private treatments resulting in extensive misuse of first- and second-line TB medications, the spread of HIV, a lack of political commitment, and, most importantly, …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 22–31 Read article
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Modelling Electronic Diode Networks with PSPICE Simulation
Abstract: The dual of Thevenin, Norton equivalent circuit is used in place of any circuit/network of linear sources and immittances at at a given frequency. Both Thevenin with Norton theorem is useful for analyses and modification of circuits, to study /obtain network’s steady state response and initial condition. Methods to represent different circuits with Thevenin/Norton impedances connected at desired nodes are given using Spice/Pspice. The Thevenin/Norton impedances connected are of other …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 2, Issue 2, 2024 · pp. 17–37 Read article
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A Critical Review of Generative Design Methods in Computer-Aided Drafting
Abstract: In the realm of Computer-Aided Drafting (CAD), generative design methods have become a potential strategy for automating and enhancing the design process. These methods generate a wide range of design possibilities based on given characteristics and limitations by using algorithms and computational tools. The objective of this critical study is to assess the benefits, drawbacks, and implications of generative design techniques in CAD. A notable result of this merger is …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Advancements in Drug Design Technology and Its Impact on COVID-19 Treatment
Abstract: The deadly coronavirus disease 19 (COVID-19) pandemic has recently spread, raising concerns about global health. The search for novel therapeutic compounds is made more necessary by the persistent problem of the absence of licensed medications or vaccinations. By saving money and time, computer-aided drug design has sped up the process of finding and developing new drugs. The structured-based and ligand-based drug discovery subcategories of computer-aided drug design (CADD) are the …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Exploring Electric Skateboards: Comprehensive Insights into Design and Modeling
Abstract: Environmental protection and energy conservation have become primary concerns in the 21st century, prompting accelerated efforts to plan and develop electric vehicle (EV) technology. EVs offer numerous advantages, including zero emissions, the establishment of a new automobile industry, economic development, and the creation of efficient and smart transportation systems. This project introduces a foot-controlled steering system designed to enhance vehicle control, making it suitable for various road conditions and reducing …
Published in Trends in Electrical Engineering · Vol. 14, Issue 3, 2024 · pp. 39–45 Read article
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Design and Performance Analysis of Microwave Filters and Resonators for High-Frequency Systems
Abstract: Microwave filters and resonators are fundamental components in high-frequency systems, playing a crucial role in signal selection, interference suppression, and frequency stabilization. This review presents a detailed analysis of design methodologies and performance characteristics of microwave filters and resonators used in modern communication and radar applications. Various filter topologies, including low-pass, high- pass, band-pass, and band-stop configurations, are examined with respect to their frequency response, insertion loss, selectivity, and bandwidth. …
Published in Journal of Microwave Engineering and Technologies · Vol. 13, Issue 1, 2026 · pp. 8–16 Read article
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Different Aspects and Processes in 3D Printing: An Overview
Abstract: 3D Printing or Additive manufacturing produces actual items from geometric representations by layering on materials one after the other. 3D printing is a rapidly developing technology. These days, 3D printing is employed all over the world. The application of 3D printing technology is expanding in the fields of agricultural, healthcare, automotive, locomotive, and aviation. It is utilized for mass modification and fabrication of various open-source designs. An object can be …
Published in International Journal of Manufacturing and Production Engineering · Vol. 2, Issue 1, 2024 · pp. 24–30 Read article
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Innovations and Practices in Ornamental Horticulture: Integrating Landscape and Garden Design for Sustainable Aesthetics
Abstract: Ornamental horticulture is a specialized branch of horticultural science focusing on the cultivation, management, and utilization of plants for decorative and environmental purposes. With growing urbanization and lifestyle shifts, the importance of aesthetically pleasing and ecologically sustainable green spaces has significantly increased. Landscape design and garden design, both integral components of ornamental horticulture, contribute not only to the beautification of spaces but also to environmental conservation, mental well-being, and biodiversity …
Published in International Journal of Trends in Horticulture · Vol. 2, Issue 2, 2025 · pp. 13–19 Read article
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Optimizing Heat Dissipation: Analysis of Air Cooled Fins for Electronic Equipments
Abstract: This paper focuses on the thermal management of electronic components in modern technologies like RADAR electronics, UAV and Drone technologies,Automotive Electronic Components etc. The main objective of this research is to design and develop an efficient heat dissipation system, using fins, for an electronic component with dimensions of 80 x 300 mm, dissipating 30W heat. The process starts by calculating essential parameters for fin design, followed by modeling the fins …
Published in Recent Trends in Fluid Mechanics · Vol. 12, Issue 3, 2025 · pp. 26–50 Read article