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188 articles for “bio-active compounds”
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Antibacterial Potentiality of SourSop Leaf and Fruit Extract: A Review
Abstract: SourSop is scientifically known as Annona muricata Linnaeus, which is a highly potent plant with a wide range of activities especially against cancer. The plant has many health benefits and all its parts have been utilized for treating various diseases. It is also used popularly to make various food items like ice creams and beverages. Lately, it has been explored for its antibacterial and anticancer properties by researchers worldwide. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 1, 2024 · pp. 59–64 Read article
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Synthesis of new heterocyclic compounds containing nitrogen, sulphur and study their biological activity
Abstract: Several substituted pyridines with brominated coumarin and with other substituents were achieved by condensing brominated coumarin IV with 4-methoxybenzaldehyde in basic solution forming α,β-unsaturated ketone II. Hantzsch reaction of this ketone with β-ketoester to provide precursor substituted pyridines. The Hantzsch reaction product was subjected to different reactions. The other targeted heterocyclic compound was obtained by reaction of α,β-unsaturated ketone II with hydrazine carbothioamide to give substituted pyrazole with brominated coumarin, …
Published in Emerging Trends in Chemical Engineering · Vol. 8, Issue 3, 2021 · pp. 8–16 Read article
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Design, Synthesis, and in vitro Evaluation of Novel Benz/Imidazole-2-acetonitrile Derivatives as Antibacterial and Antifungal Agents
Abstract: Benzimidazole is a pharmaceutically important compound. In this research, we were able to prepare several heterocyclic derivatives from it by first preparing a new azo derivative ZH through a reaction of 3-aminoacetophenone with benzimidazole-2-acetonitrile. This azo derivative was then introduced via a condensation reaction with aromatic amine derivatives, resulting in the preparation of two Schiff base derivatives Z1 and Z2. From these bases, six and seven membered heterocyclic derivatives were …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 53–87 Read article
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Application of Fruit and Vegetables Peels as Functional Ingredients in Baked Cookies: A review
Abstract: About half of the waste produced by industrial fruit and vegetable manufacture is in the form of peels, cores, pomace, and unripe or damaged fruits and vegetables. Many fruits and vegetables, including citrus, apples, peaches, pears, bananas, pomegranates, berries, mangoes, and sugar beet, have peels, pulp/pomace, and seeds that contain concentrations of phenolics and other phytochemicals that are typically much higher than in the edible tissues of those fruits and …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 2, 2024 · pp. 11–19 Read article
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The Impact of Extraction Conditions on the Trend of the Type of Red Onion and the Characteristics of Oil Harvest for the Use of Constraints
Abstract: The therapeutic potential of plant-derived medicinal products, including essential oils, has not yet been fully exploited. Many medicinal plants have been studied to provide the biologically active compounds on which most modern drugs are based. However, much more remains to be learned about their precise pharmacology. This is particularly important for essential oils which have such a concentrated but complex composition. This is the reason for the interest they generate …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 70–76 Read article
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Synthesis, Characterization of Mesoporous Zeolite BEA and Its Application in Multicomponent Reactions
Abstract: Strongly acidic mesoporous zeolite beta (MZB or Beta/MCM-41composite) with bimodal pore structure and stepwise distributed acidity has been synthesized by novel route using zeolite BEA as silica-alumina source. The material was characterized by various techniques. Powder XRD showed the existence of well-structured microphase zeolite Beta and mesophase MCM-41 in the composite materials. The performance of the composite material as a catalyst was investigated for the synthesis of various biologically active …
Published in Journal of Catalyst & Catalysis · Vol. 1, Issue 3, 2014 · pp. 25–45 Read article
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A Literature Survey on Biological Activities of Thiazolidine Derivatives
Abstract: Hetercyclic compounds play a vital role in both chemical and life sciences. Among them ,thiazolidinone represent a significant class, characterized by a five- membered saturated ring containing both sulfur and nitrogen atoms. Structurally, thiazolidinones are derived from thiazole, with sulfur position at the 1-position, nitrogen at the 3-position , and a carbonyl group typically located at the 2-, 4-, or 5- position are possible, though structural and functional diversity is …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 16–21 Read article
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Heterocyclic Substituted Flavones: Bridging Natural Products and Medicinal Chemistry
Abstract: Heterocyclic substituted flavones represent a unique and promising class of flavonoid derivatives, gaining significant attention in recent years due to their diverse and enhanced biological activities. These compounds are characterized by the incorporation of heterocyclic moieties such as quinoline, pyridine, thiazole, imidazole, oxazole, and pyrazole into the flavone structure, which significantly alters and often enhances their bioactive properties. This structural modification has made heterocyclic flavones particularly appealing as candidates for …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 23–30 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Sensory Psychology of Supergrain Bakery: Consumer Perception Beyond Taste
Abstract: Bakery products remain a cornerstone of diets worldwide, yet wheat-based formulations are increasingly supplemented or replaced as consumers demand healthier, more functional alternatives. Supergrains such as quinoa, amaranth, millet, and cowpea, together with fruit-based flours such as guava flour, have been extensively investigated to enrich wheat-based products and improve their nutritional value. At the same time, the science of sensory psychology has become central to product acceptance, as taste, aroma, …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
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Phytochemical Characterization and Antimicrobial Activity of Cassia Alata Leaf Extract
Abstract: Aim: The aim of this study was screening for bioactive compounds with pharmaceutical properties from Cassia alata leaf extract. Methodology: The dried sample of Cassia alata leaf was powdered and extracted with ethanol using soxhlet apparatus. Antimicrobial activity of the leaf extract was checked against different clinical pathogens. Result and discussion: Thin layer chromatography (TLC) revealed the number of compounds present in the leaf extract. The results suggest that they …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 3, 2019 · pp. 20–24 Read article
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Drug Discovery and Design: Focus on computational approaches used in the discovery and design of new drugs
Abstract: Computational approaches have revolutionized the field of drug discovery and design, offering efficient and cost-effective strategies for identifying and developing new therapeutics. This review article explores the application of computational methods in drug discovery, with a focus on virtual screening techniques, molecular docking, molecular dynamics simulations, and quantitative structure-activity relationship (QSAR) models. Virtual screening plays a crucial role in narrowing down large chemical libraries by utilizing ligand-based and structure-based approaches. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 1, 2023 · pp. 26–30 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions.Methods: A total of twenty-seven …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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A Comprehensive review on phytomedicinal activity of chirchita (Achyranthes aspera): an Indian Rural Medicinal Plant
Abstract: Because it is used to treat many types of diseases. Native to India, Achyranthes aspera (Chirchita) has been used in rural medicine for generations.This review explores the phytomedicinal significance of Achyranthes aspera, focusing on its bioactive compounds and the pharmacological activities that support its use in treating various ailments. This plant is a useful tool in traditional and alternative medicine. Because it has anti-inflammatory properties Antioxidants Antibacterial, anticancer and liver …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 74–85 Read article
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Synthesis and antibacterial studies of some bivalent transition metal ions Zn (II), Cu (II) and Ni (II) complexes of Schiff’s base derived from some substituted aromatic aldehydes.
Abstract: In this study, Schiff bases were synthesised through the condensation of aromatic aldehydes with primary amines and subsequently complexed with Ni(II),Zn(II) and Cu(II) ions. The formation of the metal complexes was confirmed by FTIR spectroscopy, which identified the key functional groups involved in coordination. The biological activity of the prepared compounds were studied with the help of selected bacteria like E. coli , Pseudomonas. and B. sereus.. The results obtained …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 96–104 Read article
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Synthesis, Characterization, Antibacterial Evaluation and Study of Organic Separation Behavior for Five Membered Ring for Pyridine Derivatives
Abstract: Imidazoles can be prepared by condensation between amines and various aldehydes and ketones. Imidazole derivatives are important compounds due to their broad biological activity and pharmacological properties, such as antifungal, antioxidant, cytotoxic, anti-inflammatory, analgesic, anti-YFV (yellow fever virus), anti-tuberculosis, and antimicrobial activity. In recent years, many studies have been conducted on the preparation of biological imidazole derivatives, especially derivatives linked to heterogeneous rings containing nitrogen or any other donor atom. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 106–121 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
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Synergistic biofuel production, refractometric monitoring and trypsin digestion studies from Clitoria ternatea, Cymbopogon citrates and Saccharomyces cerevisiae
Abstract: The rising demand for renewable and green energy sources has encouraged researchers to seek sustainable alternatives to fossil fuels. In the present study, an investigation was conducted on the synergistic production of biofuel from plant materials of Clitoria ternatea and Cymbopogon citratus with microbial fermentation by Saccharomyces cerevisiae. The study also evaluated the refractometric monitoring and trypsin digestion activity for the understanding of biochemical changes during biofuel production. The oil …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 2, 2026 Read article
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Protective Effects Of Curcumin Against Osteoporosis And Its Molecular Mechanism
Abstract: One of the most prevalent metabolic disorders is osteoporosis (OP), which primarily affects postmenopausal women and the elderly. It is often associated with gradual loss of bone density, ongoing destruction of bone microstructure, and increased risk of osteoporosis. Pharmacotherapy is the primary approach for treating and preventing osteoporosis. However, persistent medication therapy invariably results in drug responses and particular adverse effects. Therefore, scientists continue to search for new monomeric compounds …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 16–23 Read article
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A Review on Loading Methodologies of Active Aromatic Substance into Biopolymers
Abstract: Biopolymer-based films are increasingly being studied as sustainable alternatives to conventional packaging materials due to their biodegradability, renewability, and potential for functionalization. There are several natural polymers in the category of biopolymers such as soy protein, zein, cellulose, chitosan, and several other biodegradable synthetic polymers such as polylactic acid and polycaprolactone. However, these often show limitations in barrier properties, mechanical strength, and resistance to microbial contamination. To overcome these drawbacks, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 9–13 Read article