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64 articles for “adverse reaction”
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Adverse Drug Reactions and Pharmacovigilance of Herbal Medicines in India
Abstract: The use of ayurvedic medicines is popular in India and in recent times has become accepted in other countries. Associated with this increasing use, are growing concerns about the safety of ayurvedic medicines. This paper discusses in brief the ayurvedic concepts of adverse reactions to medicines, the need for pharmacovigilance of ayurvedic medicines, challenges in introducing pharmacovigilance in ayurveda and some recommendations to successfully implement these activities. Pharmacovigilance is the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 5, Issue 1, 2016 · pp. 10–13 Read article
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Prevalence of Adverse Drug Reactions and Risk Factors Associated with first Line Anti- Tuberculosis Drugs
Abstract: Background: The recommended first line treatment of active tuberculosis (TB) consists of rifampicin (R), isoniazid (H), ethambutol (E) and pyrazinamide (Z). The regimen is highly effective in treating active TB however it is associated with various adverse drug reactions (ADRs) posing undeniable challenges to therapy success. Objectives: To determine the prevalence of ADRs and risk factors associated with first-line anti-tuberculosis medications. Methods: A quantitative cross-sectional descriptive study conducted at the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 2, 2022 · pp. 9–16 Read article
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A Research Project on Identification and Reporting of Adverse Drug Reactions in General Medicine Ward of an ESI Hospital
Abstract: Aim: The study aims at identifying and reporting the adverse drug reactions (ADRs) in general medicine ward of an ESI hospital, Bangalore, Karnataka, India. Objective: Prescription study, analysis and prevention of medication-related problems (ADRs), identifying and minimizing medication-related problems, improving patient safety initiatives, improving the patient health-related outcomes, reducing work burden of physicians, and providing better therapy to large number of patients. Methodology: Study Design: It was a prospective and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 9–14 Read article
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Adverse Drug Reactions: A Global Health Challenge
Abstract: Adverse drug reaction (ADR) is an unfavorable event with a causal connection to the medication. It is an undesirable event occurred by a pharmacological substance. They are a major cause of Mortality all over, they are classified into augmented, chronic, bizarre, Delayed based on the severity of the damage they caused The primary causes of adverse drug reactions (ADRs) are drug overdose, drug– drug interactions, genetic variations, and individual characteristics …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 01–06 Read article
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Consumer Misuse of Cosmeceuticals and Its Role in Adverse Skin Reactions
Abstract: Cosmeceuticals represent a rapidly expanding category of products positioned between cosmetics and pharmaceuticals, offering both aesthetic and therapeutic benefits. However, their widespread availability, aggressive marketing, and perception as inherently safe have contributed to increasing instances of consumer misuse. Misuse includes over-application, inappropriate combinations, prolonged unsupervised use, and use of high-potency active ingredients without dermatological guidance. Such practices have been strongly associated with a broad spectrum of adverse cutaneous reactions ranging …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 · pp. 1–16 Read article
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AI-Powered Pharmacovigilance: Revolutionizing Adverse Drug Reaction Detection, Reporting, and Future Perspectives-A Review
Abstract: Pharmacovigilance is very important in drug safety as it monitors, identifies and prevents adverse drug reactions (ADR). Conventional pharmacovigilance systems are usually limited by underreporting and delay in signal detection as well as the inability to scale up. The pharmacovigilance sphere is undergoing a seismic shift with the arrival of AI. The use of AI-driven tools, such as machine learning and natural language processing, is transforming how ADR detection is …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 01–07 Read article
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Adverse Drug Effect of Habbe Shifa: A Case Study
Abstract: Traditional systems of medicine are practiced across different parts of India. The major traditional system of medicine in India are termed as AYUSH (Ayurveda, Yoga, Siddha, Unani and Homeopathy)—these systems are in use since centuries and are considered as safe without any side effects. Over the counter medications is also common in the name of herbal products. Generally, these herbal drugs are safe, but if not used on proper traditional …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 8, Issue 2, 2021 · pp. 1–4 Read article
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A Research Study and Report on Clinical Pharmacy Services Provided by Doctor of Pharmacy during their Clerkship and Internship Postings to a Tertiary care teaching Hospital.
Abstract: Clinical pharmacy is defined as the area of pharmacy concerned with the science and practice of rational medication use. Aim: The study aims at implementing clinical pharmacy services by Doctor of Pharmacy during clerkship and internship postings to patients at different wards of Rajiv Gandhi Institute of Medical Sciences. Objective: Prescription study and analysis and preventing the medication related problems adverse drug reactions drug interactions, over dose), performing drug utilization …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 1, 2018 · pp. 27–32 Read article
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Enhancing Patient Safety: A Study On Adr Monitoring In Tertiary Care Hospitals
Abstract: Background: Adverse drug reactions (ADRs) are a major concern in healthcare, causing patient morbidity and mortality. The objective of this study was to investigate the adverse drug reactions in a tertiary care hospital. Methods: From January to July 2024, an observational study was carried out at Bangalore's Akash Super Specialty Hospital. 51 individuals had their demographics, medications, and suspected adverse drug reactions (ADRs) gathered. The Naranjo scale was used to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 1–7 Read article
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Pharmacovigilance And Drug-Induced Toxicities: A Clinical Perspective
Abstract: Pharmacovigilance, which aims to detect, assess, and prevent medication-induced toxicities and adverse drug reactions (ADRs), is a crucial part of healthcare. This study examines the several kinds of drug-induced toxicities, such as idiosyncratic, dose-dependent, and allergic reactions, and emphasizes the function of clinical pharmacists in the tracking and treatment of these illnesses. Pharmacovigilance systems are crucial because they can identify and handle drug-related safety issues that might not surface during …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 17–30 Read article
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Molecular Mechanisms of Drug Metabolism in Anesthesia: A Pharmacogenomic Perspective
Abstract: Pharmacogenomics studies how a person’s genetic profile affects their reaction to drugs, which is vital in anesthesia. Anesthetic pharmacology depends significantly on drug metabolism, which involves complex biochemical processes that manage the absorption, distribution, metabolism, and excretion (ADME) of anesthetic drugs. The cytochrome P450 (CYP) enzyme family plays a critical role in the metabolism of various anesthetic drugs, with genetic polymorphisms leading to inter-individual variability in drug responses. Specific CYP …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 90–95 Read article
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Recombinant Insulin
Abstract: Recombinant insulin, a revolutionary product of biotechnology, has transformed the landscape of diabetes treatment. Developed through genetic engineering techniques, recombinant insulin offers a safer, more consistent alternative to traditional animal-derived insulin. Its production involves the insertion of the human insulin gene into host organisms such as Escherichia coli or Saccharomyces cerevisiae, which serve as efficient factories for insulin synthesis. Recombinant insulin is used to treat diabetic patients who are allergic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 39–43 Read article
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A Review on T POXX (TECOVIRIMAT)—A New Bioweapon Against Small Pox
Abstract: As an author in the present review, I have provided all the available information regarding T POXX (TECOVIRIMAT)—a new bioweapon against small pox—like its synonym, history of discovery and approval, chemical structure, pharmacology, adverse drug reactions, drug interactions, safety concerns, contraindications, warnings/cautions, preclinical and clinical trial information and all other information after thoroughly searching in all the available resources. I hope this can be helpful to all the healthcare professionals …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 2, 2018 · pp. 9–11 Read article
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A Short Review on CAR-T Cell Therapy in Cancer Treatment
Abstract: As an author in the present review, I have provided all the available information of CAR-T cell therapy like, definition, history of discovery, early FDA approval and types of clinical trials conducted, early manufacturers, current availability, preparation and mechanism involved, steps involved, adverse drug reactions, and its uses after referring to all available resources. I hope this review can be greatly helpful to all health care professionals, pharmacy, medical, nursing, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 27–29 Read article
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Modernizing Pharmacovigilance: Leveraging AI,Automation, and Real-World Data for Drug Safety
Abstract: Pharmacovigilance, or PV, is “the pharmacological science relating to the detection, assessment, understanding, and prevention of adverse effects, mainly long term and short-term adverse effects of medicines.” PV’s specific objectives are to increase patient care and safety when using medications and all medical and paramedical therapies; assist in evaluating the benefits, drawbacks, efficacy, and risks of medications, ensuring their safe, prudent, and more effective use; and promote clinical training, education, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 21–30 Read article
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Nutraceutics: Opening the Debate for a Framework for the Safety and Efficacy of Nutraceuticals Formulations
Abstract: As of right now, there is no precise definition for nutraceuticals that distinguishes them from other food-based categories such herbal products, dietary supplements, pre- and probiotics, functional foods, and fortified foods. Several studies have shed light on the possible mechanisms of action of pharmaceutically active ingredients in food, emphasizing their ability to improve health, lower the risk of disease, and promote general wellbeing. However, Nutraceuticals confront difficulties in substantiating safety …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 27–33 Read article
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Role of Topical Onion Extract in Scar Management at Donor Site
Abstract: Scarring is commonly caused by an imbalance between collagen synthesis and degradation. One promising approach to mitigate scar formation involves the use of onion extract, known for its ability to inhibit fibroblast activity, which plays a key role in the development of scars. Despite the widespread use of onion extract in various commercial scar treatment products, the exact molecular mechanisms through which it exerts its scar-reducing effects remain unclear.This study …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 7–11 Read article
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Thalassemia and its management – A review article
Abstract: Thalassemia is a hemoglobinopathy burdening India making it earn title of Thalassemia capital of world. Studying last decade, the overall prevalence worldwide and incidence rates have declined but prevalence rates were high in east and Southeast Asian countries. Screening for carriers and affected individuals and genetic counselling are promising approaches for reducing soaring cases and reducing the further spread. Thalassemia affects various organs due to iron overload and haemolysis leading …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 60–73 Read article
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Milk Allergy: Significance, Detection and Management
Abstract: Milk allergy is a significant public health issue, particularly among infants and young children, with prevalence rates between 2 and 6% in early childhood, declining to 0.1–0.5% in adulthood. It is an immune-mediated adverse reaction to milk proteins, primarily involving immunoglobulin E (IgE)-mediated responses. Symptoms range from gastrointestinal distress and respiratory complications to severe anaphylaxis. The etiology of milk allergy involves genetic predisposition, environmental factors, an immature immune system, and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 1, 2025 · pp. 15–19 Read article
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Mind-Gut Connection: The Psychosomatic Effects of Stress and Emotions on Digestive System
Abstract: Stress, understood as an immediate disruption to bodily equilibrium, triggers an adaptive or allostatic response that impacts gastrointestinal function both in the short and long term. The enteric nervous system communicates in both directions with the brain through parasympathetic and sympathetic pathways, collectively forming what is known as the brain-gut axis. Unani scholars describe stress as a response to the loss of something valuable, such as an opportunity, a desired …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 11–14 Read article