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27 articles for “Superoxide dismutase”
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Superoxide Dismutase: An Emerging Target for Human Therapeutic
Abstract: Superoxide dismutases (SODs) represent a very essential antioxidant guard beside oxidative stress in the body. The enzyme does something as an excellent restorative mediator next to reactive oxygen species (ROSs)-mediated multiple sicknesses. The current review portrays the curative property of SOD in diverse physiological and pathological circumstances such as cancer, inflammatory diseases, gene mutation, cardio therapy, aging, neurodegenerative diseases, and diabetes. However, the enzyme has positive boundaries in experimental applications. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 165–172 Read article
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Superoxide Dismutase (SOD) in Breast Carcinoma
Abstract: Breast cancer is the leading problem around the world predominantly in developing parts. Oxidative stress plays a crucial role in carcinogenesis especially in breast carcinoma. Disbalance in free radical and antioxidants result in oxidative stress. Enzymes like Superoxide dismutase (SOD) are used as primary defence; they directly scavenge and inactivate reactive oxygen species (ROS). Keeping this in mind, this study has been designed to study SOD in breast carcinoma before …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 94–98 Read article
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“Evaluation of superoxide Dismutase (SOD) enzyme level and some indicators in people exposed to smoke”
Abstract: The aim of this study is to assess the level of SOD enzyme and its impact in people who are exposed to smoking, in addition to measuring C-interactive protein, and finally measure a complete picture of blood samples taken from patients. The results of the current study showed there is a significant differences (p<0.05) in the activity of the SOD. The mean of SOD activity in patient was 127.9 U/ml …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 52–55 Read article
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Anti-Ulcer Activity of Ethanolic Extract of Sesamum indicum Seed on Indomethacin-Induced Ulcer Model and Its Antioxidant Property in Gastro-Protection
Abstract: The present study was intended to investigate and evaluate the antiulcer activity of the ethanol seed extract of Sesamum indicum Linn. using Indomethacin Induced Ulcer in Albino rats and to determine its link between oxidant or antioxidant parameter. The extract of Seamum indicum Linn. was tested on indomethacin induced gastric ulcer in Albino rats. The antiulcer activity of high dose (400 mg/kg) and low dose (200 mg/kg) of ethanolic extract …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 18–25 Read article
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Differential Susceptibility of Bacteriophage and Viruses to Reactive Oxygen Species
Abstract: Normal 0 false false false EN-US X-NONE X-NONE Reactive oxygen species of superoxide, hydrogen peroxide, and hydroxyl radicals were generated by mixing xanthine, xanthine oxidase and iron citrate and incubating for 5 min at room temperature. T2 bacteriophage, encephalomyocarditis (EMC) virus, adenovirus, or vaccinia virus particles were incubated with the solution for various periods of time after reactive oxygen species were formed. Physical damage to the virus particles that affected …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 2, 2016 · pp. 7–12 Read article
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Anti-Ulcer Activity of Methanolic Extract of Mucuna Pruriens Seed on Indomethacin Induced Ulcers in Albino Rats
Abstract: The present study was intended to investigate and evaluate the antiulcer activity of the methanol seed extract of Mucuna pruriens using indomethacin induced ulcer in albino rats and to determine its link between oxidant or antioxidant parameter. The extract of Mucuna pruriens was tested on indomethacin induced gastric ulcer in albino rats. The antiulcer activity of high dose (400 mg/kg) and low dose (200 mg/kg) of ethanolic extract of Mucuna …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 5, Issue 2, 2015 · pp. 1–8 Read article
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Changes of Super Oxide Dismutase Activity in Hemolymph, Hemocytes and Fat Body of Silkworm (Bombyx mori L.) Challenged by Micrococcus luteus and Escherichia coli
Abstract: The hemolymph, hemocytes and fat body of the silkworm, Bombyx mori L. were determined for superoxide dismutase (SOD) activity following bacteria Micrococcus luteus and Escherichia coli challenged using a photochemical assay system consisting of methionine, riboflavin, and p-nitro blue tetrazolium. The in vitro reduction of nitro blue tetrazolium by superoxide to formazan was measured spectrophotometrically in Bombyx Mori. Hemolymph, hemocytes and fat body were in response to various immune elicitors. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 2, Issue 2, 2012 · pp. 1–9 Read article
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Foliar Application of Zinc Nanoparticles Improves Photosynthetic Performance in Wheat Plants
Abstract: The present study investigated the impact of foliar spray of zinc oxide nanoparticles on physiological and biochemical reactions in wheat (Triticum aestivum L.) Foliar spray with zinc oxide nanoparticles at 10 mg/l positively increased pigment content and biomass in comparison to control while a significant reduction in chlorophyll content and biomass accumulation was observed at higher concentration of 1000 mg/l. A study of Chlorophyll a fluorescence parameters at 10 mg/l …
Published in Research and Reviews : A Journal of Biotechnology · pp. 12–23 Read article
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A research study into the interactions between the monoherbal formulations of arjuna and Aloe vera in a rat model of isoproterenol-induced cardiotoxicity
Abstract: Aloe vera is a herbal dietary supplement, and arjuna is used for its cardioprotective properties. Rats were given isoproterenol hydrochloride subcutaneously to cause myocardial infarction. The purpose of the study was to identify any potential pharmacodynamic interactions between the commercially available formulations of Aloe vera and arjuna. Materials and Procedures: The electrocardiogram (heart rate, ST segment elevation time, QRS complex amplitude), serum cardiac markers (creatine kinase, isoform of creatine kinase, …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 1–10 Read article
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Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 · pp. 20–28 Read article
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Effects of Chlorpyrifos as Inducer for Oxidative Stress in Liver, Kidney and Spleen of Freshwater Fish, Pseudetroplus maculatus (Bloch, 1795)
Abstract: Chlorpyrifos is one of the most common organophosphate insecticides found abundantly in freshwater ecosystems and has been detected in agricultural and fishery products worldwide. The study focused to determine the effect of chlorpyrifos on the induction of oxidative stress in freshwater fish Pseudetroplus maculatus. Fish were exposed to sublethal concentrations (0.661 and 1.32 μg/l) of chlorpyrifos for 15 and 30 days. Activities of antioxidant enzymes and the levels of hydrogen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 20–29 Read article
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Arsenic Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Arsenic (As) is a metalloid listed in group Va of the periodic chart. It exists in nature in the oxidation states +V (arsenate), +III (arsenite), 0 (arsenic) and −III (arsine). In the aqueous environment inorganic arsenic appears commonly in the oxidation states +V and +III as arsenous acid (As (III)), arsenic acid (As (V)), and their salts. Chronic and acute exposures of arsenic leads to cancer, cardiovascular disease (hypertension and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 16–37 Read article
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Effect of Ethylene Glycol Monomethyl Ether on Testicular Antioxidant System in Adult Rats
Abstract: Ethylene glycol monomethyl ether (EGME), an environmental contaminant, which is widely used as a solvent especially in lacquers, paints, dyes, pesticides, liquid soap, cleaning solution & cosmetic, chemical intermediates, as a diluent for hydraulic brake fluid etc on industrial scale, has been shown to induce reproductive abnormalities in male rats. The precise nature and mechanism of action of EGME on the male reproductive system is not clear. In the present …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 1–6 Read article
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Attenuation of Doxorubicin-induced Hepato- and Nephrotoxicity by Proanthocyanidins from Myrica nagi Bark in Wistar Rats
Abstract: Due to dose-related toxic effects, doxorubicin, a very potent and often used anti-cancer medication, is largely limited. The current research investigated the protective impact of Myrica nagi bark (PMN)-isolated proanthocyanidins on hepato-induced doxorubicin and nephrotoxicity in Wistar rats. The animals were subdivided into six classes of five rats each. Group I got PMN (200 mg/kg, p.o.) for 21 days, Group II received Doxorubicin (DXR) (60 mg/kg, i.p.) once, 48 h …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 19–28 Read article
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Biochemical Assessment of Fish Channa punctatus Exposed to Heavy Metal Loaded Waste Water with Serum Biochemistry and Oxidative Stress as Biomarker Responses
Abstract: Due to Rapid industrialization from past two decades, there has been increase in industrial wastes which has been discharged into the nearby water bodies, leading to the damage of the whole ecosystems and marine habitat. These industries possess a potential threat to the aquatic ecosystem besides, its flora and fauna. One such condition has been witnessed in the present study in MIDC Area of Amravati region of Maharashtra India. In …
Published in Research and Reviews: A Journal of Toxicology · Vol. 12, Issue 3, 2022 · pp. 33–42 Read article
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Protective Effect of Chloroform Extract of Cyperus Rotundus against DNBS Induced Inflammatory Bowel Disease in Rats
Abstract: The present study was designed to evaluate the effects of Cyperus rotundus on DNBS (Dinitrobenzene sulfonic acid) induced IBD in experimental rats. The experimental protocol (Protocol No. 9012 dated 26th Dec 2009) was approved by Institutional Animal Ethical Committee of Anand Pharmacy College. Colitis was induced with DNBS (180 mg/kg in 50% ethanol) intracolonically in animals on the 11th day of the study. Animals were fasted for 24 h prior …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 3, 2014 · pp. 24–32 Read article
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The Specificity of Antioxidants: A Review
Abstract: Antioxidants are substances that provide protection to the body against reactive chemical species. When oxidative damage is not prevented or reversed, some pathology may occur. Naturally, there are enzymatic antioxidants (example: superoxide dismutase) and non-enzymatic (example: glutathione) in the cell, and some are incorporated through the diet (example: vitamins). These substances exhibit specificity when carrying out their activity, that is why it is necessary to experiment their effects on different …
Published in Journal of Water Pollution & Purification Research · Vol. 5, Issue 2, 2018 · pp. 31–41 Read article
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Utilization of the Sibininto treat the DMBA Induced Hepatotoxicity and Free-Radical Damage in Norwegian Rat, Rattus norvegicus (L).
Abstract: DMBA is abbreviated form of the 7,12-Dimethylbenz[a]anthracene. It is working as immuno-suppressor. It also serves as a tumor initiator. It allows for a greatly accelerated rate of growth of tumor and making many cancer studies possible. The plant, Silybum marianum (L) yields pharmacologically active compound named as silbinin. The silbinin deserve documented antioxidant activity. The purpose of this study was to assess this silbinin for protective influence in DMBA induced …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 11, Issue 1, 2020 · pp. 26–36 Read article
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Effect of Seed Priming with Extract of Cissus quadrangularis on Wheat and Mung Seedlings under Different Salt Concentrations
Abstract: Salinity stress inhibits plant growth by affecting morphological, photosynthesis, antioxidant phenomena, and nitrogen metabolism, among other physiological and biochemical processes. In this study, the effects of pre-soaking wheat and mung grains in aqueous extract of Cissus quadrangularis on growth, and antioxidant activity of salt-treated plants, were investigated. The pre-soaking of grains in extract demonstrated a significant enhancement in growth parameters. The activity of superoxide dismutase (SOD), guaiacol peroxidise (GPOX), ascorbate …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 10, Issue 3, 2021 · pp. 1–11 Read article
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Influence of Methanolic Extractives of Prepupal Stages of Black Soldier, Hermetia Illucens L. (Diptera: Stratiomyidae) on the Biochemical Parameters of Serum and Liver in the DMBA Induced Toxicity in Norwegian Rat, Rattus Norvegicus (L)
Abstract: The larvae of Black soldier fly (BSF), Hermetia illucens L., are reducing the environmental pollution through utilization of organic waste for their development on organic wastes and converting the organic waste into protein and fat rich biomass. Health promoting potentials of black soldier fly derived proteins as ingredient of diet appears to be crucial need of modern days. In present attempt, forty Norwegian Rats were utilized as experimental animals. The …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 12, Issue 3, 2021 · pp. 1–19 Read article