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12 articles for “Recovery Profile”
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Comparison of Recovery Profile for Total Intravenous Anaesthesia (TIVA) Using Propofol And Remifentanil in Laparoscopic Surgeries
Abstract: Total Intravenous Anaesthesia (TIVA) has become an increasingly preferred technique in modern anaesthetic practice due to advantages such as reduced postoperative nausea and vomiting (PONV), improved hemodynamic stability, minimal environmental impact, and faster recovery compared to conventional inhalational anesthesia. Propofol in combination with remifentanil is widely used for TIVA because of its rapid onset and offset of action, which supports quick postoperative awakening and enhanced patient satisfaction. Target Controlled Infusion …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 39–50 Read article
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Prospective Evaluation of the Optimal Concentration and Effect of Epinephrine as an Adjuvant to Local Anesthetics for Prolonging Block Duration and Reducing Systemic Toxicity in Outpatient Surgery
Abstract: Purpose: To evaluate the optimal concentration and effect of epinephrine as an adjuvant to local anesthetics for prolonging block duration and reducing systemic toxicity in outpatient surgery. Methods: The study involved a randomized double-blind clinical trial on 80 adult patients awaiting day-care extremity surgery. The patients were randomly assigned to two groups of equal size. One group, Group E, was given the local anesthetic agent along with epinephrine as an …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 64–69 Read article
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Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article
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Clinical Profile of Dengue Patients who had a Prior Infection with the Covid 19 Virus in a Tertiary Care Centre
Abstract: This cross-sectional analytical study conducted in a tertiary care center aims to investigate the clinical profile of Dengue virus-infected patients with a prior history of COVID-19 within the last three years. Dengue, a prevalent tropical disease, ranges from mild fever to severe conditions like hemorrhagic fever and shock syndrome. The study utilizes the World Health Organization's 2009 classification for Dengue and delineates the febrile, critical, and recovery phases of infection. …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 34–38 Read article
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Enhancement of LVRT Capability in DFIG based Microgrids Using STATCOM
Abstract: The improvement of a grid-connected wind microgrid's Low Voltage Ride-Through (LVRT) capability using a Static Synchronous Compensator (STATCOM) is investigated in this research. The increasing penetration of wind energy into modern power systems necessitates advanced control strategies to maintain grid stability during voltage disturbances and fault conditions. In this study, a STATCOM is employed with an effectively tuned PI controller to provide enhanced dynamic response, voltage regulation, and reactive power …
Published in Trends in Electrical Engineering · Vol. 16, Issue 2, 2025 Read article
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Drug Induced Immune Mediated Nephritis: Molecular Mechanism , Pathways and Clinical Implications
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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Analytical Method Development and Validation of Simultaneous Estimation of Natural Active Constituents Andrographolide and Piperine by UV Method.
Abstract: A simple, accurate, precise, and robust UV-Visible spectrophotometric method was developed and validated for the simultaneous estimation of Andrographolide and Piperine in bulk and combined pharmaceutical dosage forms. Preformulation studies confirmed favorable physicochemical properties for both drugs, including acceptable solubility profiles, melting points, pH values, and partition coefficients. The method development involved determination of λmax values at 224 nm for Andrographolide and 288 nm for Piperine using ethanol as solvent. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 33–41 Read article
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Investigation of the Thermoelectric, Electronic Band Profile, and Structural Properties of Skutterudites Based on Cobalt and Antimony
Abstract: We investigated ThCo4Sb12, an actinium-filled skutterudite, from the ground up for structural, electronic, and thermoelectric properties. A generalized gradient approximation and modified BeckeJohnson potentials were used to calculate the exchange-correlation potential. The compound is shown to have metallic properties in the electronic structure calculations. Actinium series element is used as a void filler in this study. The Seebeck coefficient and electrical conductivity can be calculated using Boltzmann's transport theory. According …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 2, 2024 · pp. 13–19 Read article
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Pharmacogenomics in Anesthesia: Case Studies and Clinical Applications for Personalized Care
Abstract: Pharmacogenomics, the study of how genetic variability influences individual responses to medications, is transforming anesthetic practice by enabling personalized care. This case study collection explores the integration of pharmacogenomic insights into anesthesia management, highlighting its impact on safety, efficacy, and patient outcomes. Adverse reactions to anesthetics often arise from genetic polymorphisms that alter drug metabolism or sensitivity. For instance, patients with RYR1 mutations are susceptible to malignant hyperthermia (MH) when …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 85–91 Read article
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AI-Driven Inverse Design of Functionally Graded Bio-Nanocomposites for Sustainable High-Barrier Packaging
Abstract: Multilayer plastic packaging realizes high barrier performance through laminated heterogeneous structures, but the heterogeneous structure has severe end-of-life challenges caused by the interfacial incompatibility of materials and the poor recyclability. This study proposes the inverse design of functionally graded PLA-nanoclay composite films by reinforcement learning as a monolithic alternative to traditional multilayer systems. Twin-screw extrusion is designed as a continuous control Markov decision process, and proximal policy optimization (PPO) is …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1547–1564 Read article
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Preoperative Use of Midazolam vs Dexmedetomidine for Anxiolysis in Day-Care Surgery
Abstract: Surgical procedures trigger significant fear and anxiety that can adversely affect physiological responses and recovery outcomes. This prospective, randomized, double-blinded clinical trial compared the anxiolytic efficacy and safety of intravenous midazolam and dexmedetomidine in 60 patients undergoing day-care surgery. Primary outcomes included anxiety scores measured by STAI and sedation assessed by the OAAS scale at multiple perioperative time points. Secondary outcomes assessed in the study included detailed evaluation of hemodynamic …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 7–12 Read article
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Molecular Mechanisms of Drug Metabolism in Anesthesia: A Pharmacogenomic Perspective
Abstract: Pharmacogenomics studies how a person’s genetic profile affects their reaction to drugs, which is vital in anesthesia. Anesthetic pharmacology depends significantly on drug metabolism, which involves complex biochemical processes that manage the absorption, distribution, metabolism, and excretion (ADME) of anesthetic drugs. The cytochrome P450 (CYP) enzyme family plays a critical role in the metabolism of various anesthetic drugs, with genetic polymorphisms leading to inter-individual variability in drug responses. Specific CYP …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 90–95 Read article