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1984 articles for “R” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
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Risk Management in Civil Engineering by FTA, FMEA and Risk Matrix
Abstract: Infrastructure projects, particularly in civil engineering, are fraught with uncertainties that manifest as both physical and financial risks. The project report, titled Quantifying and Managing Financial and Physical Risks in Infrastructure Projects, aims to bridge the existing gap between managing these two critical categories of risks. By integrating advanced statistical methodologies such as Failure Mode and Effects Analysis (FMEA), Fault Tree Analysis (FTA), Risk Matrix, and Regression Analysis, this study …
Published in Journal of Structural Engineering and Management · Vol. 12, Issue 1, 2025 · pp. 34–46 Read article
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A Research Study on Navigating Medication Risks Through MFRS (Medication Fall Risk Score and Evaluation Tool) and DART (Drug Associated Risk Tool) Among Patients with Polypharmacy
Abstract: Background information: The advancements in medical science continue, but the safety of medication usage is still a question mark and has become a crucial area for researchers to focus on. In the need of the above, various scoring systems and tools have been developed in pharmacy practice research. Prior to the present work, we did a systematic review and meta-analysis and identified two such tools: the medication fall risk score …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 1–13 Read article
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Reliability-Aware Mathematical Model for Radiation-Hardened Satellite Communication Systems
Abstract: Satellite communication systems operate in radiation environments in which total ionizing dose (TID), displacement damage, and single-event effects (SEE) can progressively degrade electronic, optoelectronic, and communication components and can ultimately reduce link availability and mission reliability. This paper develops a Reliability-Aware Radiation-Hardened Satellite Communication Model (R-RHSCM) that mathematically couples the orbital radiation environment, accumulated radiation dose, component degradation, communication-link performance, single-event failure probability, redundancy, thermal effects, and adaptive mitigation. The …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 15, Issue 2, 2026 Read article
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A Retrospective Analysis of Resin-Based Polymer Composites and Bioactive Glass-Polymer Hybrids Regarding Secondary Caries and Durability
Abstract: Aim- To compare the 2-year clinical survival and failure modes of a Resin-Based Polymer Composites and BioactiveGlass-Polymer Hybrids in Class I and II posterior restorations. Methods-A total of 550 restorations were placed in adult patients across various private dental practices in India to ensure a diverse clinical demographic. Teeth were randomly assigned and restored with either a hybrid composite (Te-Econom, IvoclarVivadent; n=275) or a Resin-Modified Glass Ionomer Cement (GC Gold …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1089–1095 Read article
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Exergy Analysis of Vapor Compression Refrigeration System with Refrigerants R134a, R152a, R290 and R32
Abstract: Abstract This paper pressents exergy analysis of vapour compression refrigeration system with refrigerants R134a, R152a, R290and R32. This analysis helps to understand the effect of irreversibility on thermodynamic processes. It shows exergy losses in different components of the system and hence leads to improve the performance of different components of the system. A computational model has been developed to study the effects of evaporator temperature and condenser temperature on COP, …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 2, Issue 3, 2015 · pp. 11–19 Read article
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Rainfall-runoff Modeling using HEC-HMS Hydrologic Model for Guder River Watershed, Blue Nile Basin, Ethiopia
Abstract: Rainfall-runoff modeling is important for a number of hydrologic applications including flood forecasting, water resource planning and management. This study presents the result of a watershed rainfall-runoff modeling for Guder river watershed having area of 6597 km 2 using Hydrologic Engineering Center-Hydrologic Modeling Systems (HEC-HMS). The watershed runoff is varying spatially and temporally due to manmade factors and natural factors on the watershed. These issue needs efficient water resource planning …
Published in Journal of Water Resource Engineering and Management · Vol. 8, Issue 2, 2021 · pp. 62–77 Read article
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Great Women of India Like Ahilyabai Holkar, Rani Durgavati, Rani Bhabani, Rani Bhavashankari, Rani Rasmoni: Lessons for Making New India 2047
Abstract: Introduction: Since ancient times, women have struggled to navigate a society dominated by men. Despite years of planned development in India, women still have a lower status in society, and their socio-economic conditions remain significantly worse than those of men. Time has come to take Lessons from our Great Women, like Ahilyabai Holkar, Rani Durgavati, Rani Bhabani, Rani Bhavashankari, Rani Rasmoni and others to make New India 2047. Objective: The …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 2, 2025 · pp. 39–44 Read article
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3D Evaluation of Various Rotary Instruments for the Removal of Gutta-Percha and Resilon from Root Canals
Abstract: Aims: To assess the effectiveness of Protaper and Mtwo retreatment files in the elimination of gutta-percha and Resilon from uncomplicated root canalsMethods and Material: Thirty six freshly extracted single rooted teeth with Weine’s class I canal configuration were taken. The crowns were de-crowned to a depth of 16mm, and the working length was determined to be 15mm. Root canal preparation was done using rotary Protaper universal files and irrigated with …
Published in Research and Reviews: A Journal of Dentistry · Vol. 14, Issue 2, 2023 · pp. 7–11 Read article
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Analysis on Decadal Variation of Reservoir Area and Perimeter with Respect to Rainfall and Population
Abstract: Water is an essential element for the survival and proper functioning of all life forms on Earth. In the state of West Bengal like many other regions groundwater rivers and water canals serve as the primary sources of water. This vital resource is distributed across various sectors including agriculture households and industrial facilities following necessary treatment processes. West Bengal's climate is characterized by a tropical monsoon type in its southern …
Published in Journal of Water Resource Engineering and Management · Vol. 11, Issue 3, 2024 · pp. 32–40 Read article
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Interfacial Performance and Structural Stability of Repaired vs. Replaced Polymer-Based Composites: A 3-Year Retrospective Analysis of 'Patch-up' Restorative Engineering
Abstract: Objective: This retrospective study aimed to evaluate the clinical longevity and interfacial success of repairing aged polymer-based composites versus complete replacement, focusing on the integration between the existing polymer matrix and the new restorative material. Materials and Methods: A retrospective clinical audit was conducted on 50 cases (n = 50) of posterior restorations with localized defects. The sample was categorized into: Group A (n = 25), where defective sites were …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 180–187 Read article
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Development and Validation of a Robust RP-HPLC Method for Rufinamide Quantification in Pharmaceutical Dosage Form
Abstract: The creation and validation of a simple, precise, and targeted reverse phase high-performance liquid chromatographic (RP-HPLC) approach allowed for the quantification of rufinamide in pharmaceutical dosage forms. With a mobile phase of methanol and water (50:50, v/v), the technique used a gradient mode Symmetry Qualisil gold C18 column (4.6 x 150mm, 5 μm). For the detection method, a flow rate of 1 mL/min was employed at 220 nm. During a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 25–32 Read article
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Recombinant Proteins and Nested Gene Regulation: Nutrient Driven Immune Response and Disease Resistance in Livestock
Abstract: Livestock production systems are increasingly challenged by infectious diseases, metabolic disorders, and environmental stressors that reduce productivity and compromise animal health. Advances in molecular biology and animal nutrition now offer new opportunities to strengthen disease resistance through integrated strategies that combine recombinant protein technologies, gene regulatory mechanisms, and nutrient mediated immune modulation. This review examines how recombinant proteins and nested gene regulation interact to shape nutrient driven immune responses in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 84–97 Read article
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Role-Based Online Food Ordering and Delivery System Using Django and RESTful Architecture
Abstract: Traditional food ordering processes in restaurants rely heavily on manual interactions, including in-person ordering, phone-based bookings, and unstructured coordination between customers, restaurants, and delivery personnel. These approaches lead to inefficiencies such as delayed order processing, incorrect order handling, lack of real-time tracking, and poor coordination among stakeholders. Although modern applications exist, many academic implementations lack modular architecture, role-based access control, and scalable backend design. This paper presents the design and …
Published in Recent Trends in Programming languages · Vol. 13, Issue 1, 2026 · pp. 01–11 Read article
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Experimental Investigations of Mass Flow Rate on Regression Rate of Hybrid Rocket
Abstract: A number of practical hybrid propulsion systems developed for booster and upper stage application,at different Centers across the globe. The regression rate of hybrid fuel plays an important role ondevelopment of viable hybrid propulsion system. In the present investigation an effort has been madeto study the regression rate behavior of PVC-DBP((C 2 H 3 Cl) n )-DBP(C 16 H 22 O 4 ) hybrid fuel burning inthe stream of gaseous …
Published in Journal of Experimental & Applied Mechanics · Vol. 12, Issue 2, 2021 · pp. 31–51 Read article
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Characteristics and Comparison of Continuous Casting Machine (CCM) and Reheat Furnace (RHF) Rolled Reinforcement Bar
Abstract: Modern rolling process introduces manufacturing of reinforcement bar in combination of continuouscasting and straight rolling to avoid time and cost losses and produce fine quality reinforcement bar.Using the core heat or heat inside the raw material (generally known as billet), the rolling process iscarried out. This modernized rolling process overcomes reheating losses and cost of transportationand of course cost of reheating which were faced in previous manufacturing processes. During therolling, …
Published in Trends in Mechanical Engineering & Technology · Vol. 11, Issue 1, 2021 · pp. 17–27 Read article
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Reducing Environmental Impact through Optimized Non-Renewable Resource Management: A Systematic Review of Technological Advances
Abstract: The term "optimized use of non-renewable resources" describes the prudent management and optimization of limited natural resources that are difficult to replenish or regenerate quickly. Minerals, nuclear fuels, and fossil fuels (coal, oil, and natural gas) are examples of resources that are not renewable. The abstract idea is to minimize waste, the impact on the environment, and the pace of depletion while optimizing the utility obtained from these resources. Advanced …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 3, 2024 · pp. 12–19 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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Navigating Risk-Based Approaches in Quality Assurance: Strategies, Implementation, and Impact
Abstract: This review investigates the implementation of a risk-based approach within Quality Management Systems (QMS) as stipulated by ISO 9001:2015 regulations. It scrutinizes the challenges organizations encounter when transitioning to ISO 9001-2015 requirements, particularly focusing on the alignment of conceptual frameworks and processes among stakeholders. A key objective of this review is to propose a refined definition of "quality risk" and "risk-based thinking in QMS" to address the idiosyncratic characteristics of …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 Read article
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A Review on Effects of Waste Tire Rubber Polymer on Fresh, Mechanical, and Impact Resistance Properties of Rubberized Concrete
Abstract: According to the collective findings of numerous researchers, waste tire rubber has proven to be a valuable addition to concrete, contributing to advancements in construction. Rubber crumb is artificial rubber polymers, such as butadiene rubber (BR). The chemical composition of tire rubber crumb that is discarded can be represented by the combination of (C5H8)n, (C8H8)x-(C4H6)y, (C4H6)n, C, S8, ZnO, and complicated hydrocarbons. Various studies have explored the mechanical and impact …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 469–478 Read article