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12 articles for “Blood loss”
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Assessing Efficacy and Safety: Oxytocin Monotherapy vs. Oxytocin + Carbetocin Combination Therapy
Abstract: Objective: Comparing the Effectiveness between Oxytocin monotherapy and Oxytocin + Carbetocin. Methods: A prospective, non-randomized, observational study focusing on 221 women with CS was conducted. The patients eligible based on inclusion and exclusion criteria were screened and final sample size was 139. Individual patient data including patient demographics, medical history, OT notes, pre and post CBC reports, and safety data were obtained from the patient records. The study compared between …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 40–51 Read article
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The Study of Nutritional Requirements and Physiological Changes in Space Station
Abstract: This article focuses on the impact of physiological adaptations to weightlessness on nutrient and food requirements in space. These modifications entail reductions in body water and plasma volume, which affect the cardiovascular and renal systems. Spaceflight poses intricate and predominantly detrimental effects on the human body, spanning both short and long durations. Long-term weightlessness leads to significant issues like muscle atrophy, skeletal deterioration, cardiovascular function deceleration, reduced red blood cell …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 7–10 Read article
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A summary continuation analysis evaluating the prevalence and predictors of diabetic retinopathy in newly diagnosed type 2 diabetic patients.
Abstract: Context: Diabetic retinopathy (DR), the leading cause of acquired blindness in adults, affects approximately 93 million people globally. It is a serious complication of type 2 diabetes, resulting from prolonged damage to the blood vessels in the retina. Although largely preventable and treatable, DR continues to be the main cause of vision loss among working-age adults and significantly impacts quality of life. While most studies on DR in Nepal have …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 21–30 Read article
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An Approach towards in Management of Chronic Kidney Disease
Abstract: The current international guidelines define and classify the chronic kidney disease (CKD) as decreased kidney function shown by decreased glomerular filtration rate (GFR). Glomerular filtration rate of 60 ml/min/1.73 m 2 for at least 3 months is a marker for kidney damage. The underlying causes for chronic kidney disease are proteinuria and hypertension. It is the main cause of CKD in many high-, middle- and low-income countries. In different countries, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 1, 2025 · pp. 9–15 Read article
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Studying the effects of Exposure to Chemicals on The brain and Nervous System and The risk of Chemical Pollution
Abstract: Scientific research and studies on chemical pollution show that exposure of the brain and nervous system to chemicals causes serious damage ranging from cognitive, motor, and nerve cell disorders to chronic diseases such as Alzheimer's and neurological paralysis. These substances (such as lead ions, mercury, solvents that combine and dissolve easily in the blood, and pesticides) disrupt neurotransmitters and cause cell damage, especially during the early stages of body development. …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 Read article
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Association of Vitamin D Binding Protein BP rs2282679 Gene Polymorphism and Serum Levels of Vitamin D in Patients with Vitiligo
Abstract: For vitamin D to have an impact, the vitamin D receptor (VDR) must be expressed and activated in the nucleus. The VDR has several known genetic variants. Biological impacts can be caused by changes in DNA sequences known as "polymorphisms" that are common in the population. Vitiligo is a disease that causes loss of skin color in patches, and it is a chronic (long-lasting) autoimmune disorder loss of color. The …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 45–52 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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Hearing, Speech, and Language Characteristics in a Case with Hemoglobinopathy Secondary to Beta Thalassemia Intermedia
Abstract: Background: Thalassemia is an inherited disorder characterized by a reduced amount or absence of hemoglobin, the oxygen-carrying protein inside the red blood cell. Thalassemia has its types called alpha and beta-thalassemia. Beta thalassemia is a condition in which there is a reduction or deficit in the synthesis of the beta-globin chain of hemoglobin molecules caused by a mutation in chromosome eleven. Beta thalassemia can be broadly categorized into three main …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 1–5 Read article
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Exploring the Dynamic Mechanical Analysis and Biocompatibility of Compression-Molded PMMA for Biomaterial Applications
Abstract: Metals such as titanium, cobalt, and magnesium are commonly used as biomaterials. However, their use can lead to tissue reactions due to the formation of foreign bodies which may cause blood cancer. Researchers have addressed this issue by substituting biomaterials with polymethyl methacrylate materials (PMMA). The PMMA material being studied is produced using the compression molding technique. This article examines the mechanical properties and biotoxicity of PMMA. These materials have …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 482–499 Read article
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Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Developing an Assessment Protocol in Ayurvedic Research for Hyperemesis Gravidarum with Special Reference to Garbhini Chardi
Abstract: Garbhini Chardi (nausea and vomiting in pregnancy) is described in Ayurvedic texts as one of the Vyakta Garbha Lakshanas – early physiological signs indicating pregnancy. However, when this symptom becomes excessive, persistent, or distressing, it may transition from a normal event to a pathological condition, requiring timely intervention to safeguard maternal and fetal health. In advanced stages, it leads to day-to-day incapacitation, weight loss, dehydration, and metabolic disturbances – clinically …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 44–61 Read article
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Mind-Gut Connection: The Psychosomatic Effects of Stress and Emotions on Digestive System
Abstract: Stress, understood as an immediate disruption to bodily equilibrium, triggers an adaptive or allostatic response that impacts gastrointestinal function both in the short and long term. The enteric nervous system communicates in both directions with the brain through parasympathetic and sympathetic pathways, collectively forming what is known as the brain-gut axis. Unani scholars describe stress as a response to the loss of something valuable, such as an opportunity, a desired …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 11–14 Read article