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18 articles for “ATP”
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Molecular Docking Studies for the Identification of Mycobacterial Adenosine Triphosphate (ATP) Synthase Inhibitors Using Active Phytocompounds from Plants Curcuma longa, Curcuma zedoaria and Galipea officinalis
Abstract: Objective: Tuberculosis (TB), known in human history for several decades, remains the second leading infectious disease after COVID-19. Still, the occurrence of TB increases due to the bacterium’s greater survival nature. They can survive in extreme conditions by being in long latency and adapting to the host. This study seeks to identify potential inhibitors from Curcuma longa, Curcuma zeodaria, and Galipea officinalis based on ancient folklore and compare them against …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 16–26 Read article
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Free Fatty Acids Modulate the Specific Activity and Expression of Alpha and Beta Subunits of Sodium Potassium ATPase of Cultured Rat Cortical Astrocytes.
Abstract: The fatty acid composition of the membrane plays an important role in the functioning of the membrane-bound enzyme Na+K+ATPase. The aim of this study was to determine the effects of the free fatty acids at various levels of unsaturation, namely, stearic acid, linoleic acid, arachidonic acid and docosahexaenoic acid, on the alpha and beta subunits of sodium potassium ATPase present on the primary cultures of rat astrocyte membrane. Membrane was …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 2, Issue 1, 2012 · pp. 20–28 Read article
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In vivo Modulatory Effect of Clerodendrum Splendens (Glory Blossom) in Aluminum Induced Alzheimer Diseases and Lonchocarpus Sericeus in Rotenone Induced Parkinson’s Disease on Na+/K+ Atpase (Sodium Pump) in the Cerebral Tissues of Male Albino Wister Rats
Abstract: Elegant research has shown that plants are useful for both curative and preventive purpose on the humans populous. Prevalent among diseases associated with humans are neurological diseases which affect a large sector of the population especially the elderly. The most common neurological diseases are Parkinson and Alzheimer disease which affect a large sector of the brain and also cause an imbalance in brain electrolyte. Among such electrolytic mechanisms of the …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 31–36 Read article
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Effective Antibiotics and ATP Loaded Delivery System in the Management of Diabetic Wounds
Abstract: The aim of present research work was to formulate and evaluate antibiotics and ATP-loaded delivery system (liposome) in the management of diabetic wounds. Wound is disturbance in the normal skin anatomy and their functions; tissue injury resulting in the “loss of continuity of epithelium with or without the loss of underlying connective tissue.” Wound bad is an ultimate situation for wound infection, while wound healing is a complex and dynamic …
Published in Research and Reviews : A Journal of Immunology · Vol. 3, Issue 2, 2013 · pp. 1–10 Read article
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Effectiveness of Assertiveness Training Programme on Knowledge and Attitude of Adolescent Girls Regarding Prevention of Sexual Abuse
Abstract: Introduction: Sexual violence against girls is a global human rights violation of vastproportion with severe health and social consequences. In this view, a pre experimental studywas conducted to assess the effectiveness of Assertiveness Training Programme (ATP) on theknowledge and attitude of adolescents regarding prevention of sexual abuse. The objectives ofthe study were to develop and assess the effectiveness of ATP in terms of gain in knowledgeand attitude for adolescent girls …
Published in Journal of Nursing Science & Practice · Vol. 10, Issue 2, 2020 · pp. 57–61 Read article
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Enzymes used in Alcohol Fermentation
Abstract: Fermentation is the process that uses enzymes to cause chemical reactions in biomass feedstocks. In biochemistry, it is defined as the extraction of energy from carbohydrates in the absence of oxygen. The science of fermentation is known as zymology. Cellular respiration is the process in which a carbohydrate, like starch or sugar, is converted into an alcohol or an enzyme by an organism. Fermentation is a process in which yeast …
Published in Journal of Catalyst & Catalysis · Vol. 8, Issue 3, 2021 · pp. 15–21 Read article
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Application of Aqueous Two-Phase Systems in the Extraction of Bovine Serum Albumin
Abstract: Protein partitioning in an aqueous two-phase system (ATPS) has been found to be a powerful method for extracting and separating mixtures of biomolecules. In ATPS, many factors influence the partition coefficient K (which is the ratio of protein concentration in the top phase to that in the bottom phase) and the recovery percent (Rec%). Two systems of ATPS were used: first, polyethylene glycol (PEG4000)/sodium phosphate, and second, PEG4000/dextran. The behavior …
Published in Journal of Polymer & Composites · Vol. 11, Issue 1, 2023 · pp. 41–50 Read article
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Bedaquiline: An In-Depth Exploration into Its Antitubercular Significance
Abstract: Tuberculosis is still a leading infectious disease and a major threat to public health. Although there has been a slow decrease in the incidence over years, its “hard to kill nature” is responsible of about 2 million deaths in HIV infected individuals annually. Bedaquiline, a Diaryl-Quinoline drug was fast-track approved as an orphan drug to combat drug resistance. It shows potent activity against Mycobacterium tuberculosis by interfering with the production …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 06–14 Read article
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Estimation of Effective Storage Time in Post-thawing and Washing Cryopreserved Red Blood Cells using Mechanical Properties of Membrane by Dielectrophoresis
Abstract: Aim: The aim of the study is to estimate most effective storage time after thawing and washing in cryopreserved red blood cells(RBCs), using the mechanical properties of red blood cells(RBCs) membrane by dielectrophoresis. Materials and Methods: The mechanical properties of the RBCs membrane(elasticity, electric capacity and interactive energy) were calculated by mathematical model made from dielectrophoresis on RBCs. In addition, estimating the most effective storage time after thawing and washing …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 1, 2021 · pp. 31–39 Read article
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Molecular Docking, QSAR Modeling, and ADMET Evaluation of Novel Pyrazolo-Pyrimidine Derivatives as Potential CDK-2 Inhibitors for Cancer Therapy
Abstract: Cyclin-dependent kinase-2 (CDK-2) is an essential regulator in cell cycle progression and is an important therapeutic target in cancer drug development. In the present study, an integrated computational approach involving molecular docking studies, QSAR modeling, ADMET prediction, and artificial intelligence-based analysis was used to identify pyrazolo-pyrimidine derivatives as potential CDK-2 inhibitors. Based on the molecular docking results, it was found that selected compounds exhibited high binding affinity towards the ATP …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
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Metabolic Reprogramming in Carcinogenesis: An Overview
Abstract: Metabolic reprogramming is a crucial mechanism via which cells modify their metabolic pathways to adjust to changes in the environment and maintain growth, survival, and function. This phenomenon is of utmost importance in a wide range of physiological and pathological situations, specifically in cancer, immunological responses, and stem cell biology. In cancer, metabolic reprogramming facilitates fast cell growth and survival, as demonstrated by the Warburg effect, where cancer cells prioritize …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 32–38 Read article
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Thermodynamic Irreversibility in Semen Transport
Abstract: Sperm ejaculation is a vital reproductive process that involves both complex biological functions and energetic mechanisms. Beyond the physiological aspects, thermodynamics offers a framework to analyze energy conversion, exergy use, and irreversibility during sperm activity. ATP provides the main source of exergy for motility, but part of this energy is inevitably lost as heat and entropy generation, reflecting inefficiencies in the process. Because heat regulation directly affects metabolic rates, motility …
Published in Journal of Thermal Engineering and Applications · Vol. 13, Issue 1, 2026 Read article
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Automatic Tyre Inflation And Deflation System in Automobiles
Abstract: Modern cars have a lot of features and electronic systems which support the driver in dangerous driving situations. Such systems are not only developed for keeping the cars under control, but they also try to improve the subjective feeling during driving and comfort. One of such systems has the task to measure and control the pressure of the tyres: Automated Tyres Pressure System (ATPS).The system is can be placed in …
Published in Journal of Automobile Engineering and Applications · Vol. 6, Issue 1, 2019 · pp. 1–4 Read article
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Slope Stability Analysis by Swedish Slip Circle Method Using C-Programming
Abstract: The side slopes of an earthen dam should be safe against shear failure. Out of the various methods of stabilityanalysis of slopes, “Swedish Slip Circle Method” is commonly used in practice. Here in the Swedish circlemethod, potential failure surface is assumed to be cylindrical in shape (i.e., circular in cross section). Afterdetermining the actuating and resisting forces for assumed failure surface, the factor of safety is calculated. Theslope is considered …
Published in Recent Trends in Civil Engineering & Technology · Vol. 1, Issue 1-3, 2011 · pp. 47–68 Read article
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Biochemical Analysis of Cadaveric Synovial Fluid for Determination of Death Interval
Abstract: Estimation of post-mortem interval or time since a death has always remained an important requirement in medico-legal autopsies. Since the 1850s, scientists have been working on different methods to determine post-mortem interval but none of the methods is either or collectively reliable in measuring exact death interval because of environmental factors. Hence in this study, synovial fluid sodium concentration was investigated to predict post-mortem interval. Total 100 samples of the …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 3, 2019 · pp. 1–6 Read article
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Sub-acute Toxicity of β-cyfluthrin in Hepatic Tissue and its Amelioration through Punica granatum in Swiss albino mice
Abstract: β-cyfluthrin, member of synthetic pyrethroid pesticide Type II is broadly used multipurpose insecticide. Widespread and indiscriminate use of β-cyfluthrin leads to environmental contamination and toxicity towards nontarget mammalian systems. The present study was undertaken to examine toxic manifestation of β-cyfluthrin in hepatic tissue of Swiss albino mice and also evaluate possible mitigative potential of pomegranate juice (PJ) in combating pesticide induced hepato-toxicity. Animals were divided into five groups namely, control, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 41–52 Read article
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Harnessing the Bioactive Potential of Calotropis gigantea and Calotropis procera
Abstract: The medicinal plants of the Apocynaceae family Calotropis gigantea and Calotropis procera have gained more and more interest as source of bioactive molecules for biomedical applications like cancer therapy. They have various pharmacological activities, which are believed to be linked to various phytochemical constituents such as cardenolides, cardiac glycosides, flavonoids, triterpenoids, steroids, phenolic compounds, alkaloids, and proteins in their latex. The recent molecular and cellular studies show that extracts and …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article