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184 articles for “immune T cells”
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Innovative Antifungal strategies: Terbinafine hydrochloride in Niosomal carriers
Abstract: Onychomycosis, an infection caused by fungi that affects fingernails or toenails, causes the nails to grow, separate from the nail bed, and become discoloured. While anybody can get, those with weakened immune systems, children and the elderly are especially susceptible. Present study was related to formulate an effective nail lacquer that would treat onychomycosis by utilizing Terbinafine hydrochloride. In this study, niosomes of a medication called terbinafine hydrochloride, an antifungal …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 1–16 Read article
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The Effect of Prepared Biochemical Compounds on Cancer Cells
Abstract: The effect of prepared biochemical compounds affecting cancer cells, where the chemical compounds are divided into two parts, some of which are treatment for cancerous tumors, and others activate cancer cells such as glucose and sugars, which increase the size of the cancerous tumor and its spread in the body. While chemotherapy usually refers to the use of antitumor drugs to treat cancer through a cytotoxic treatment method. It also …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 1, 2022 · pp. 14–20 Read article
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Impact of a Structured Educational Program on Awareness of the Human Papilloma Virus Vaccine for Cervical Cancer Prevention Among Women in a Chosen Rural Region of Rajkot
Abstract: The World Health Organization (WHO) advocates for the inclusion of the human papilloma virus (HPV) vaccine in standard immunization schedules worldwide, in addition to other preventive strategies. The launch of the prophylactic HPV vaccine has markedly improved primary prevention measures against cervical cancer and other diseases caused by HPV. Following their approval in 2006, both the quadrivalent and bivalent HPV vaccines have received authorization in over 100 countries. As of …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 18–22 Read article
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Effects of Intraperitoneal Administration of ATRA on the Testis of Elastase Induced Emphysematous Rats
Abstract: Emphysema is the pathological manifestation primarily associated with lungs. However, there are evidences of extra-pulmonary manifestations related to emphysema. The inflammation developed during emphysema triggers the release of several inflammatory mediators, which affects the proximal as well as distal organs. The present study was designed to determine the effect of inflammatory spillage on testicular tissue of male Sprague dawley rats; moreover, the main focus was to assess the potential role …
Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 3, 2016 · pp. 1–12 Read article
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Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 07–22 Read article
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Long-Term Effects of Feeding High-Lignin Forage to Ruminants: Implications for Productivity, Health, and Sustainability
Abstract: The long-term feeding of high-lignin forage to ruminants can significantly impact various aspects of animal performance, health, and environmental sustainability. Lignin, a complex phenolic compound present in plant cell walls, is indigestible by rumen microbes, leading to reduced fiber digestibility and decreased nutrient utilization. Over time, feeding ruminants with forages high in lignin results in a decline in voluntary dry matter intake (DMI), inefficient energy and protein absorption, and suboptimal …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 30–45 Read article
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Extracellular Vesicle-Based Liquid Biopsies: Decoding the Tumor Microenvironment for Precision Oncology
Abstract: The tumor microenvironment (TME) plays a pivotal role in cancer initiation, progression, and therapeutic response. Decoding the TME is, therefore, essential for advancing precision oncology. Extracellular vesicles (EVs), including exosomes and microvesicles, are nanoscale lipid bilayer particles secreted by tumor and stromal cells. They transport a wide range of bioactive molecules, such as DNA, RNA, proteins, lipids, and metabolites, which reflect the dynamic state of the TME. Recent advances in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 43–62 Read article
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A Comprehensive Review of Ethnobotanical Studies on Traditional Indian Herbal Plants for Lung Cancer Management
Abstract: Lung cancer is a leading cause of cancer-related deaths in the world. Current therapies for lung cancer are often limited by many side effects. This review compiles and evaluates ethnobotanical evidence and modern scientific findings of Indian herbal plants traditionally used for respiratory and tumor-related disorders, with a focus on their relevance to lung cancer management. Herbal phytochemicals and how they show their potent activities were also listed in this …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 1, 2026 · pp. 1–7 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 62–79 Read article
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A short review on scenario of Type 1 diabetes in Australia
Abstract: Type 1 diabetes (T1D) is caused by an autoimmune attack on pancreatic beta cells that leads to insulin deficiency. The incidence of T1D in Australia has doubled over the past 20 years. T1D treatment focuses on physiological insulin replacement, aiming for near-normal blood glucose levels. Morbidity and mortality result in hypoglycemia in T1D. Better results can be achieved by following some of the new technologies which includes insulin pumps, continuous …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 2, 2019 · pp. 1–5 Read article
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Biodegradable Polymer Nanocarriers Composites for Biomedical Applications
Abstract: Smart polymeric nanocarriers, or SPNs, have evolved into a fascinating means of delivering medications especially to cancer cells. By improving the efficacy of chemotherapeutic treatments while lowering their negative effects, they have achieved a significant progress in exact medicine. Made to respond to certain elements in the tumours microenvironment, such as enzymes, temperature, pH, and redox conditions, these nanocarriers this reaction to triggers guarantees the release of the medicine at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 293–305 Read article
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An Overview of Gene Therapy
Abstract: Gene therapy is a revolutionary technique in medical science that seeks to cure or stop illnesses by means of introducing, altering, or quieting genes inside a patient's cells. Advancements in molecular biology, genetics, and biotechnology have propelled this field forward markedly changed over the last few decades. The underlying idea of gene therapy is to introduce genetic material into target cells via viral or non-viral vectors to rectify faulty genes, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 89–105 Read article
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Bioconjugates and Biohybrid Polymers: Intricate Cellular Integration Methods and Sophisticated Biofunctionalization Techniques for Tailored Properties in Medical Contexts
Abstract: Bioconjugates are made when biological molecules are covalently linked to manufactured polymers. They can be used in many ways for imaging, diagnosis, and specific drug delivery. Getting perfect cellular fusion is very important for how well they work. Biomolecules can be attached to polymer scaffolds in a controlled way using techniques like click chemistry and site-specific conjugation. This makes sure that the molecules connect optimally with their biological targets. Using …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 227–243 Read article
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Compliance of Animal Bite Patients Managed by Intradermal Route of Antirabies Vaccination
Abstract: Rabies is one of the oldest recognized diseases affecting humans and one of the most important zoonotic diseases in India. Intradermal ARV has been started in the tertiary hospital where this study was done from December 2010. To know the compliance of animal bite patients managed by intra-dermal route of ARV and the reasons for delay or missing the scheduled dosage of ARV, a prospective study was conducted enrolling 250 …
Published in Research and Reviews : A Journal of Immunology · Vol. 3, Issue 1, 2013 · pp. 8–15 Read article
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Down’s Syndrome (DS): A Genetic Disorder
Abstract: Down’s syndrome (DS) is a chromosomal disorder which occurs due to an error in cell division subsequently leading to an extra 21st chromosome. DS or trisomy 21 is a condition where an individual has 47 chromosomes in each cell instead of 46. It is a multisystem disorder as it affects more than one system of our body. As a consequence, impairments in both cognitive ability and physical growth take place …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 21–26 Read article
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Uncovering the Comparative Efficacy of Antiviral Drugs and Caricapapaya Phytocompound as VP2H inhibitors in Ebola virus: An Insilico Molecular Docking Analysis
Abstract: The Ebola virus is a fatal disease that transmits from wild animals to humans. Infected individuals' body fluids such as spit, blood, perspiration, faeces, blood, saliva, breast milk, sperm, or fomites can transmit Ebola. Adhesion to cell membranes and penetration into the host organism are essential aspects in viral growth. The presence of VP24, as well as nucleoproteins and structural proteins, is necessary for nucleocapsid formation and integration. The inhibition …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 62–78 Read article
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Cancer Chronicles: An Overview of its Origins, Types, Treatment, and Prevention
Abstract: Cancer is a multifaceted illness characterized by abnormal cell growth and dissemination throughout the body. Its onset usually arises from a mix of genetic mutations and environmental factors. There exist more than 100 distinct forms of cancer, each possessing unique attributes, risk elements, and therapeutic alternatives. Cancer is a pervasive health challenge that knows no boundaries of age, race, or background, continuing to rank among the foremost causes of mortality …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 36–42 Read article
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Effect of Nicotine on Cytokine Production by Human Mononuclears: Perspective of COVID-19
Abstract: Nicotine is present in the tobacco-containing products such as cigars, cigarettes, chewing tobacco, snus (an oral tobacco) and pipe tobacco. In Indian population, nicotine containing products are consumed by the 57% of population either in chewing form or smoking form. The correlation of nicotine and lung cancer in chronic smokers as well as nicotine consumption and COVID-19 incidence has to be justified. Hence current research was carried to study the …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 8–11 Read article
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To Study Prevalence of Celiac Disease in Chronic Diarrhoea Patients in North India Region
Abstract: Celiac disease (CD) is a disorder of an inflammatory T-cell response to the proteins called “gluten” and characterized by the presence of typical auto antibodies and histological alterations of the small bowel mucosa. It is a common but frequently unrecognized disease. To study the prevalence of celiac disease in chronic diarrhoea patients in north India region and study the effects of gluten free diet in these patients clinically, serologically and …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 1, 2015 · pp. 27–30 Read article
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A Study on Clinical Characteristics and The Impact Of Covid-19 In Hemodialysis Patients
Abstract: Background: The Corona Viruses Disease-19 pandemic has severely impacted Hemodialysis patients, who are vulnerable due to compromised immune systems and underlying comorbidities. Frequent Dialysis center visits increase their exposure risk to severe acute respiratory syndrome- Coronavirus Disease, and chronic inflammation, uremia, and immunosenescence may impair their immune response. Methods: This retrospective study included 60 Hemodialysis patients diagnosed with COVID-19 between January -July 2024. Data on demographics, clinical characteristics, laboratory results …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 2, 2025 Read article