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226 articles for “ageing disorder”
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Chemotherapy: Side Effect and Management
Abstract: Cytotoxic drugs are therapeutic agents intended for but not constrained to, the treatment of cancer. These drugs are kenned to be highly toxic to cells, mainly through their action on cell reproduction. Cytotoxic drugs are increasingly being utilized in a variety of health care settings, laboratories and veterinary clinics for the treatment of cancer and other medical conditions such as rheumatoid arthritis, multiple sclerosis are autoimmune disorders. Cytotoxic drugs are …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 3, 2016 · pp. 30–40 Read article
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A Clinical Study based Observation on Prevalence of Altered Liver Enzymes among Patients of Hepatobiliary Diseases Attending National Institute of Unani Medicine, India
Abstract: Background: Hepatobiliary disease is a major health problem responsible for millions of deaths annually. As reported, more than 40 million deaths occur annually in South-East Asia Region due to hepatobiliary diseases. This study was conducted as a clinical trial to assess the efficacy of Unani formulation, from which the data on prevalence of altered liver enzymes among patients of hepatobiliary diseases in which the study participants were collected and compiled …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 1, 2021 · pp. 5–11 Read article
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Integrative Network Biology Analysis of GSE6011 Uncovers Molecular Signatures in Duchenne Muscular Dystrophy
Abstract: Duchenne muscular dystrophy (DMD) is a rare, severe neuromuscular disorder demonstrated by progressive skeletal muscle deterioration and premature mortality. Despite advances in supportive care, no definitive cure exists, highlighting the need to explore novel molecular targets. The current study aimed to uncover key dysregulated genes and molecular pathways in DMD through a dataset-specific network biology approach. Publicly available microarray data (GSE6011) from DMD quadriceps muscle biopsies of 22 patients and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 36–48 Read article
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Machine Learning Approach to Predict the Mental Health Issues of Employees in Tech Companies
Abstract: Mental disorders are conditions that have an impact on your emotions, thoughts, and behaviour. It may happen infrequently or have a persistent effect. The topic of mental health has been major and challenging, especially for working professionals. Over time, the urbanized living and workload put a strain on people, making them more vulnerable to mental disorders like anxiety and mental disorders. Working professionals therefore seem to be at an elevated …
Published in Journal of Computer Technology & Applications · Vol. 13, Issue 3, 2022 · pp. 1–10 Read article
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Dietary Habit, Anthropometric Measurements and Haematological Parameters in Correlation with Prevalence of Iron-Deficiency Anaemia among Never Married Tribal Female Postgraduates of Assam, India
Abstract: Iron deficiency (ID) is the most common nutritional deficiency and familiar cause of anaemia worldwide. Among the tribal population of India, the scenario of anaemia is severe. Eating habit along with a number of genetic haemoglobin (Hb) disorders has been found to modify the morbidity and mortality of these populations. Providing information on causes and prevalence rate on anaemia among tribal population in one of the severely affected international border …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 2, 2018 · pp. 19–26 Read article
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Understanding Trichotillomania: Exploring and Managing Hair-Pulling Disorder
Abstract: One form of traumatic alopecia is called trichotillomania, which is characterized by an overwhelming impulse to take out hair and a feeling of comfort once the hair has been removed. Alopecia in trichotillomania results from the patient’s deliberate act of pulling out their own hair, often triggered by feelings of stress, tension, or psychological distress. This condition, classified as a mental health disorder, leads to noticeable hair loss that can …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 Read article
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Gene Expression Profiling in Autism Spectrum Disorder: A Microarray Analysis Using Gse42133
Abstract: Autism Spectrum Disorder (ASD) is a diverse neurodevelopmental disorder characterized by difficulties in social interaction, communication impairments, and restricted or repetitive patterns of behavior. Despite its increasing prevalence, the underlying molecular mechanisms remain poorly understood. Advances in transcriptomics offer opportunities to investigate the gene expression changes that may contribute to ASD pathophysiology. In this study, the microarray dataset GSE42133 was analyzed, which comprises gene expression profiles from peripheral blood samples …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 37–48 Read article
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Understanding the Impact of GMO on Hormones and Their Effect on Mood: A Review Paper
Abstract: The research evaluates how consuming genetically modified organisms affects endocrine functioning that can potentially lead to mood changes or disorders. This is a systematic review paper that analysed sixty publications before selecting thirty which were obtained from Sciencedirect, Frontiers, Springer, Oxfordacadamic, Cabidigitallibrary, Wileyonlinelibrary, Cambridgeuniversitypress, Scijournals, Mdpi, Metabolismjournal; while using Prisma Flow Diagram as the research tool; acknowledging that human hormonal health risks from GMO consumption remain largely unknown due to …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 3, 2025 Read article
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Recent Progress in Addressing Temporomandibular Joint Ankylosis
Abstract: TMJ ankylosis refers to the fusion of the mandibular condyle with the skull's base. Managing this condition is a formidable task due to technical complexities and a high recurrence rate.[1] Addressing temporomandibular ankylosis is a complex endeavor often resulting in reankylosis, relapse, risky complications, and necessitating multiple surgeries. This article introduces a treatment protocol for managing temporomandibular joint ankylosis, emphasizing early intervention using modern treatment approaches." Temporomandibular joint (TMJ) ankylosis …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 2, 2023 Read article
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Environmental Pollutants and Biodiversity Loss: Analyzing the Role of Persistent Organic Pollutants in Ecosystem Decline
Abstract: Persistent Organic Pollutants (POPs) significantly impact biodiversity, with various factors influencing their effects on species and ecosystems. Species in poor body condition, like carnivores and predators, are more vulnerable to POPs due to weakened immune systems and reduced detoxification abilities. Dietary habits also affect the accumulation of POPs, as chemicals biomagnify up the food chain. Carnivores accumulate higher concentrations, leading to reproductive failures, hormonal imbalances, and death, while herbivores face …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 1, 2025 · pp. 9–20 Read article
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Unlocking the Healing Powers of Aṣl Khāliṣ (Honey): Exploring Its Functional and Therapeutic Potential
Abstract: Aṣl Khāliṣ (honey) as a natural product has grabbed the attention of researchers as a reciprocal and indispensable remedy. Honey has been used to heal both internal and external ailments for much longer than medicine has existed. Unani scholars have mentioned its action in classical literature as a nutritional agent, as well as a natural food supplement with therapeutic antibacterial, anti-inflammatory, cleansing, deobstruent, lithotryptic, and wound-healing properties. According to contemporary …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 17–23 Read article
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Study on the Diagnostic Classification and Clinical Psychological Characteristics of Depression in General Clinical Setting
Abstract: AbstractObjectives: The aim of the study is to propose the diagnostic classification and to reveal clinical psychological characteristics of depression that can be seen in digestive department. Method: After verification of depression by Hamilton Depression Rating Scale to 120 patients with digestive disease, we assessed and classified depression by etiology, psychological and somatic symptoms considering biological factors (gender, age etc.). Results: we classified depression in general clinical setting into psychosomatic …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 2, 2020 · pp. 17–23 Read article
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Neuroprotective Effects of Curcuma longa: A Review of Its Role in Neurodegenerative Diseases
Abstract: Curcuma longa (turmeric), a perennial herb notably utilized in traditional medication, has garnered big clinical attention due to its major bioactive compound, curcumin. Curcumin, well-known shows a couple of organic activities, together with antioxidant, anti-amyloidogenic, and neurodegenerative effects, making it a promising candidate for the management of neurodegenerative diseases (NDDs), which include Alzheimer’s illness, Parkinson’s disorder (PD), Huntington’s sickness (HD), and amyotrophic lateral sclerosis (ALS). This evaluate consolidates current findings …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 24–32 Read article
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Revisiting the Role of Mindfulness-based Stress Reduction in the Management of Rheumatoid Arthritis
Abstract: Rheumatoid arthritis (RA) is a type of arthritis characterized by a chronic inflammatory disorder that primarily affects the lining of the synovial joints resulting in progressive disability in the movement of diarthrodial joints and arthralgia. It is a debilitating disease associated with premature death and socioeconomic burdens. Its pathogenesis is multifactorial with an individual course of progression where psychological stress is considered to be one of the risk factors associated …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 19–28 Read article
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Polycystic Ovary Syndrome: A Current Update from Literature
Abstract: PCOS (polycystic ovary syndrome) is an endocrine condition that affects women of reproductive age and can have catastrophic consequences. Menstrual irregularities, hirsutism, evidence of hyperandrogenism, and insulin resistance are all indicators of PCOS. PCOS individuals are more likely to suffer reproductive, metabolic, and cardiovascular problems. The pathogenesis of PCOS is complicated by a number of factors, including genetics, environmental factors, hormonal imbalances, obesity, ovarian dysfunction, and hypothalamus pituitary malformations. Despite …
Published in Research and Reviews: A Journal of Health Professions · Vol. 12, Issue 3, 2022 · pp. 1–21 Read article
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Therapeutic Approach for the Management of Bawaseer (Hemorrhoid)
Abstract: Varicosities of the veins of anal canal are known as hemorrhoids. Hemorrhoids or piles are a common ailment among adults. More than half of men and women aged 50 years and older will develop hemorrhoid symptoms during their lifetime. It occurs in the anal canal and causes both discomfort and embarrassment to the sufferers. Direct costs to the health care system and indirect cost through absence from work are high. …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 1, 2018 · pp. 1–5 Read article
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Studying the effects of Exposure to Chemicals on The brain and Nervous System and The risk of Chemical Pollution
Abstract: Scientific research and studies on chemical pollution show that exposure of the brain and nervous system to chemicals causes serious damage ranging from cognitive, motor, and nerve cell disorders to chronic diseases such as Alzheimer's and neurological paralysis. These substances (such as lead ions, mercury, solvents that combine and dissolve easily in the blood, and pesticides) disrupt neurotransmitters and cause cell damage, especially during the early stages of body development. …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 Read article
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In silico analysis of Abrus precatorius L. as a potential agonist of PPARγ : A novel approach to the treatment of diabetes
Abstract: Diabetes mellitus is a chronic disorder that is characterized by a lack of insulin secretion by the pancreas or a defect in insulin action, or both. If diabetes is not controlled, over time it can cause damage to blood vessels and nerves, leading to life-threatening complications such as, kidney damage, heart disease and vision impairment. It can also weaken the immune system, making patients more prone to infection. Although treatments …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Computational Approaches to Understanding Cellular Signaling Pathways
Abstract: Cellular signaling pathways are fundamental in regulating vital processes, such as cell growth, differentiation, and apoptosis. The intricate and interconnected nature of these signaling networks requires sophisticated methods for their analysis. Computational approaches, including mathematical modeling, network analysis, and machine learning, have revolutionized the way researchers analyze and simulate cellular signaling. This article provides a comprehensive overview of computational strategies employed to model signaling pathways, with a focus on integrating …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 8–13 Read article
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A Randomized Controlled Open Clinical Study to Evaluate the Efficacy of Nagara Ksheera Nasya in the Management of Ardhavabhedaka with Special Reference to Migraine
Abstract: Background: One of the 11 forms of Shiro-Roga is called Ardhavabhedaka, and symptomatically similar to Migraine, which is a neurovascular disorder. Panchakarma procedures and many formulations are described in Ayurveda for the management of Ardhavabhedaka. Since Acharya Chakradatta described Nagara-Ksheera Nasya Karma in the context of Shiro-Roga- Chikitsa, an An effort has been made to assess the efficacy of using it for the management of Ardhavabhedaka. Objective Assess the effectiveness …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 10, Issue 1, 2023 · pp. 18–32 Read article