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323 articles for “mono-”
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Global Burden of Major Depressive Disorder: Prevalence, Diagnosis, and Impact: A Comprehensive review
Abstract: In this review, we will discuss about the major depressive disorders on the basis of neurobiological changes. MDD, a prevalent psychiatric condition, manifests as a complex interplay of genetic, environmental, and physiological factors with a substantial impact on individuals and societies globally. Here the clinical assessment is fully based on diagnosis and the statistical manual for mental disorder, 5th edition (DSM-5). The pathophysiology involves Diagnosis alterations in neurotransmitter systems, dysregulation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 54–62 Read article
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Phytochemical Profile & Therapeutic Potential of Clematis Terniflora: A Comprehensive Review
Abstract: Clematis terniflora is a plant comes under the family Ranunculaceae, which is folk medicinal plant which is found widely in China, according to the Chinese medical system, Clematis terniflora is a widely distributed folk remedy that is used to cure rheumatoid arthritis, asthma, syphilis, gout, malaria, dysentery and used as analgesic, antitumor, anti-inflammatory, diuretic, antibacterial, antioxidants and anti-inflammatory etc. It is distributed around the world like China, Japan, Korea, Mongolia, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 16–24 Read article
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Practical approach for Type 2 Diabetes: Role of DPP4 Inhibitors
Abstract: Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have become essential in managing type 2 diabetes mellitus (T2DM) due to their ability to enhance incretin hormone activity, which promotes insulin secretion and inhibits glucagon release. These agents effectively lower HbA1c levels by 0.5–1.0%, are weight-neutral, and have a low risk of hypoglycemia, making them suitable for a broad patient population, including the elderly. The antidiabetic market in India is vast. Gliptin as group row …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 20–26 Read article
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Producer Gas Generation by Utilizing Paddy Straw as a Biomass Feedstock in an Open Core Downdraft Gasifier
Abstract: In present day scenario, the burning of paddy straw seriously affects the environment in India. This paper research work is utilized to solve the above-mentioned problem. In this research work, a downdraft gasifier is used for the gasification process of paddy straw for generating Producer gas (PG). The process is carried out with air as gasifying agent. The gas composition, calorific value, temperature, and efficiency are taken as performance characteristics …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 301–310 Read article
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Experimental Study on Load Transfer Mechanism in Columns Retrofitted by Bonding Precast Segments and FRP Wrapping
Abstract: An experimental study was conducted to investigate the load transfer mechanism in columns retrofitted with precast segments and Fiber-Reinforced Polymer (FRP) wrapping. As the demand for structural retrofitting grows, it becomes crucial to comprehend the behavior and effectiveness of retrofit techniques to ensure the safety and integrity of existing infrastructure. The study involved subjecting a series of column specimens to axial compression loads in order to evaluate the load transfer …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 153–165 Read article
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Novel Nanotherapeutics for the Management of Diabetes
Abstract: Diabetes is a severe chronic disorder with hyperglycemia, either due to dysfunctional pancreas(Type I) or due to malfunctioned glucose utilizing entities like: liver, straight muscle or adipocytes (Type II). Type 1 or Insulin-dependent/Juvenile diabetes and Type 2 Diabetes Mellitus or Non-Insulin dependent/Adult-onset diabetes are the two broad classifications of diabetes. In case of type 1 diabetes injectable insulin is the major form of medication given and in case of Type …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 1, 2024 · pp. 46–67 Read article
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Impact of Various Front-line Hypertensive medication on Blood Pressure Control During Maximum Exercise Testing in Coronary Artery Disease Patients
Abstract: It has long been known that blood pressure (BP) and cardiovascular morbidity are related. It is acknowledged that blood pressure during activity may serve as a more reliable indicator than resting blood pressure, which might not accurately reflect blood pressure at other times. Goals: 1) To assess how blood pressure behaves during physical activity in individuals with coronary artery disease (CAD) whose hypertension is managed with first-line antihypertensive medications. 2) …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 37–41 Read article
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Integration of IoT and Environmental Science: Vehicle Emission Monitoring Perspective
Abstract: — Since automobiles are the primary source of environmental pollution, an increase in automobile ownership also results in an increase in air pollution. Gases such as methane, butane, LPG, smoke (MQ2), carbon monoxide (MQ7), and hydrogen gas (MQ8) are all released from the vehicle as it smokes. Cars produce around half of the MQ2, MQ7, and one-fourth of the MQ9 in our environment, which contributes to global warming. The number …
Published in Journal of Microcontroller Engineering and Applications · Vol. 11, Issue 2, 2024 · pp. 1–9 Read article
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IoT Based Fire & Gas Detection Using Blynk
Abstract: This article provides a Blynk platform-based Internet of Things (IoT) solution for gas and fire detection. The suggested system has sensors that are linked to a microcontroller and can detect gas leaks as well as fires. These sensors provide wireless data transmission to a central processing unit. Safety and monitoring systems are only two of the many facets of daily life that the Internet of Things (IoT) has transformed in …
Published in Journal of Thermal Engineering and Applications · Vol. 11, Issue 2, 2024 · pp. 30–36 Read article
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Voices of Confinement and Rebirth: The Yellow Wallpaper, Daddy and Lady Lazarus
Abstract: Female authors in contemporary literature play a crucial role in reshaping the portrayal of mental illness, offering nuanced narratives deeply rooted in women's experiences. They address the complex intersection of mental health and societal expectations, exploring themes such as gender roles, body image, and trauma with sensitivity. These authors highlight women's unique challenges in treatment systems and advocate for gender-sensitive approaches in mental healthcare. Through diverse and complex characters, female …
Published in Emerging Trends in Languages · Vol. 1, Issue 2, 2024 · pp. 21–30 Read article
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Zn Doped CuO Nanoparticles for Increasing the Longevity of The Agricultural Products †
Abstract: Nanotechnology is an enabling technology at the service of mankind. Indeed, enhancing the long-term storage of agricultural products (post-harvest during transportation and storage) in general and apples and tomatoes, in particular, is a challenge. Zn-doped CuO is a proven nanomaterial with special ability to kill plant pathogens as well as a variety of microorganisms (bacteria, virus, and fungus). Much of the review is focused on the landmark papers published by …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 14–29 Read article
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Immunotherapy Advancements in Cancer Treatment
Abstract: Immuno-oncology has been one of the more exciting developments in the field of cancer treatment since about a century ago, with William B. Coley's work in the late 19th century, which really gave the field its beginnings with "Coley's toxin." In an initial effort that proved unsuccessful, early immunotherapy approaches utilizing bacterial mixtures to induce immune responses against tumors nonetheless laid some groundwork for this field. It wasn't until over …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 22–28 Read article
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An Insilico Study of Isobutrin and Phosphorylase Kinase - A Ray of Hope for Psoriasis Patients – Clinical Hypothesis
Abstract: Psoriasis is a chronic, hyper-proliferative and inflammatory skin disease. Increased levels of the calmodulin-containing enzyme, namely, phosphorylase kinase (PhK), were observed in the human epidermis of the active psoriasis cases. Thus PhK is a potential biomarker for the diagnosis and progression of the skin disease, namely, psoriasis. The search for the potential molecules that could supress the over expression of PhK is underway and any break-through in this direction leads …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 1–8 Read article
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Strategy to Accelerate the Biopharmaceuticals Production Using Komogataella phaffii (Pichia pastoris)
Abstract: Revenue generation has been the primary goals for nations as well as the industries worldwide. Biopharmaceutical verticals have become potential revenue generators as they are the industrial workhorses and the economic engines that drive the upcoming biopharmaceutical industries with advances in DNA recombinant technology. A breakthrough in the indusrial biotechnology for the production of biopharmaceuticals using Pichia pastoris is awaited. Ablynx NV, Recombinant proteins (RP), HSA-pFSH beta, antibodies, borosin, N-glycoprotein, …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Experimental Evaluation of MDM@Gd2O3:Eu3+ and Protein@MDM@Gd2O3:Eu3+ Functional Nanomaterial
Abstract: Lanthanide cation like Eu3+ (europium Xe 4f66s0) doped functional nanomaterials of lanthanide oxides especially of gadolinium oxide (Gd2O3) as nanorods capped with monodispersed macromolecule (MDM) like polyvinylpyrrolidone (PVP) coated with natural biopolymers like proteins as human serum albumin (HSA) have been the most demanding and applied nanomaterials in areas of the biosensor, optical distinguisher, electronic fluoresces, upconversion, and surface plasmonic resonance (SPR) nanomaterials and others. The Gd3+ and Eu3+lanthanide cations …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 214–223 Read article
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Structural, Electrical and Optical Properties of RGO-Incorporated PVA Nanocomposites for UV Shielding Applications
Abstract: Polymer matrix-based nanocomposites reinforced with appropriate nanoparticles have the potential to exhibit improved electrical, optical and mechanical properties, as well as improved UV-shielding capabilities. These materials are currently being utilised for various commercial applications, such as window shields and automotive components. We prepared reduced graphene oxide (rGO)-incorporated polyvinyl alcohol (PVA) polymer nanocomposites employing a solution casting method. XRD and SEM results confirmed that the rGO nanosheets were dispersed well in …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 119–137 Read article
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Discourse of Self and Other in Landscape by Harold Pinter
Abstract: This paper explores Harold Pinter’s Landscape as a pivotal representation of the complex dynamics between the subjective self and social reality. It investigates how the characters' introspection blurs the line between objective and subjective truths, highlighting their disillusionment with present-day existence and their reliance on past memories for solace. Through a dialectic discourse, Pinter’s characters reconstruct their identities and relationships, presenting fragmented versions of truth that reveal the unreliability of …
Published in Emerging Trends in Languages · Vol. 2, Issue 1, 2025 · pp. 10–17 Read article
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Exploring the Future of Operating Systems: Architectural Innovations and Kernel Development Trends
Abstract: Modern applications and the rapid evolution of hardware technologies are challenging operating system (OS) design. This paper speculates the future of OS based on revolutionary architecture advancements and emerging possibilities in kernel construction. The growth of multi-core processors, spread-bound processing, and edge architectures have challenged traditional OS paradigms. The paper provides an analysis of the progress in microkernel and monolithic kernel structures, discussing the bandwidth capacity as well as security …
Published in Journal of Operating Systems Development & Trends · Vol. 11, Issue 3, 2024 · pp. 38–47 Read article
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Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Jabuticaba Skin Flour AsA Functional Food Ingredient: Phenolic Profile, Antioxidant Potential and Functional Technological Properties
Abstract: Brazilian-native fruit, jabuticaba, is a member of the Myrtaceae family that is typically consumed naturally. The jabuticaba skin flour (JSF) is rich in phenolic compounds, the most active antioxidants present in plants, being able to stop oxidative damage and reduce the risk of oxidative stress linked to different degenerative diseases, thus become interesting to the consumer. Despite all this antioxidant potential, little is known about their characterization and about the …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 3, 2024 · pp. 01–08 Read article