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465 articles for “Toxic effects”
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Role of MSG (Monosodium Glutamate) in DNA Breaks by Cellular Method: A review article
Abstract: - Monosodium glutamate (MSG) is a generally used food additive to enhance flavors. It has been found that though is one of the most common flavoring agents used worldwide, MSG’s accumulation in the body can cause genomic damages. These genomic damages can be identified through various methods such as Random Amplified Polymorphic DNA polymerase chain reaction (RAPD - PCR). Some herbal extracts have medicinal properties that can initiate DNA repair …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 10, Issue 2, 2023 · pp. 1–5 Read article
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Effect of Pesticides on Human Health
Abstract: The use of pesticides has become a major attribute of modern agricultural practices. Though the application is useful to prevent various diseases of plant and pest attack, it is also harmful to environment and human health at certain level. The pesticides are exposed to human by dermal, oral and inhalation routes that can lead to various adverse health conditions. The mixed effect and specific effect of pesticide may vary and …
Published in Research and Reviews: A Journal of Health Professions · Vol. 7, Issue 2, 2017 · pp. 30–40 Read article
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Exploring the Synergistic Effects of Heavy Metal contaminants on Aquatic Organisms
Abstract: Human activities have a profound effect on aquatic habitats by altering water and sediment quality, which in turn impacts resident organisms. These changes are primarily caused by pollutants from agricultural, industrial, and health-related sources. Industrial effluents, often containing hazardous heavy metals such as chromium, manganese, and lead, are a major source of environmental toxicity. The discharge of these pollutants makes water unsafe for drinking, irrigation, and industrial uses, necessitating effective …
Published in International Journal of Marine Life · Vol. 1, Issue 2, 2024 · pp. 17–20 Read article
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Unlocking Wellness by Ayurveda with Contrasting Modern Medicine
Abstract: In the modern world, we are so subordinate to drugs that we are unable to imagine a single day without them. Like smartphones, we are also addicted to pharmaceuticals, which significantly impact our lives. Constant utilization of medicine makes resistance and dependence on the medicament. It moreover has diverse side effects that cause various health hazards. As people become aware of this, the utilization of herbal remedies has expanded worldwide. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 16–20 Read article
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Therapeutic Effect of PEGylated Phytosomes Loaded with Herbal Drugs for Treating Paediatric Leukaemia
Abstract: To treat pediatric leukemia, this study evaluated a co-encapsulated pegylated phytosome system based on herbal anti-cancer medications. In this study, herbal drug-soy lecithin complex-loaded phytosomes were prepared as drug carriers to overcome the limitations of natural drugs like poor absorption, low oral bioavailability, poor aqueous solubility, and so on. This is a targeted nano-drug delivery that enhances the absorption and bioavailability of the herbal drug used. In this study, herbal …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 24, Issue 3, 2022 · pp. 48–69 Read article
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Harnessing Nature: Formulations for Colon Cancer Prevention and
Abstract: Colon cancer, a rapidly advancing disease worldwide, involves the carcinogenesis of the distal part of the intestine. This malignancy progresses through various developmental stages necessitating diverse treatment approaches. Traditional treatments include drug therapy and chemotherapy; however, emerging methods, such as the use of phytochemical compounds offer promising mechanisms for combating this disease. Phytochemical compounds derived from natural food sources, including flavonoids, tannins, resveratrol, and epigallocatechin-3-gallate, exhibit potent anti-cancer properties. They …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 11–23 Read article
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Antipsoriatic Potential of Polyherbal Paste
Abstract: AbstractPsoriasis is a common dermatitis affecting 1-3% of the population. Several attempts have been made in overcoming psoriasis with prolonged treatment duration. The oral anti-psoriatic agents though quite effective are associated with renal, hepatic and hematological toxicities. The topical treatments have also been described in the classical Unani literature. This work aims in evaluating antipsoriatic potential of Barg-e-Neem, Barg-e-Henna, and Kamela that exhibit anti-inflammatory activity and are used in traditional …
Published in Research & Reviews : Journal of Herbal Science · Vol. 8, Issue 3, 2019 · pp. 20–32 Read article
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A Study and Report on the Role of Clinical Pharmacy Services Provided by the Doctor of Pharmacy in the Management of Thyroid Disorders (Hyperthyroidism and Hypothyroidism) to a Tertiary Care Hospital
Abstract: Thyroid hormones affect the function of virtually every organ system. In children, thyroid hormone is critical for normal growth and development but in adults, the main role of these thyroid hormones is to maintain stability. The main thyroid hormones which play such an important are the Thyroxine (T4) and Triiodothyronine (T3) hormones. Hence, Thyroid disorders encompass a variety of disease states affecting thyroid hormone production or secretion that result in …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 25–38 Read article
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Valeton Phytoconstituents from Curcuma Phaeocaulis as Prion Protein Mutant V210I Inhibitors: A Computational Docking and Virtual Screening Study
Abstract: Objective: Creutzfeldt-Jakob disease (CJD), a neurological disorder that is sporadic, fatal, communicable, and worsens rapidly, is caused by abnormal folding of prion proteins. Identifying and assessing the potential of phytocompounds from the Curcuma phaeocaulis Valeton plant as a new therapeutic candidate aimed at the treatment of CJD is the objective of this research article. Methods: In this experiment, we assessed outcomes following an in-silico assessment to design a new oral …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article
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Review on Functional and Histological Effect of Lead on the Central Nervous System
Abstract: Environmental and occupational exposure to a large number of chemicals occurs at various stages throughout human life. The nervous system is the organ that appears to be the most sensitive and chief target for lead-induced toxicity in comparison to other organs. Lead is also found in lead-glazed ceramics, and food is eaten or stored in containers painted with lead-based paint or lead-containing glaze may contain significant amounts of lead. Lead …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 9, Issue 3, 2019 · pp. 29–33 Read article
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Unveiling Nature’s Potential: In Silico Exploration and Identification of Herbal Remedies for Major Depressive Disorder Through Molecular Interaction Studies
Abstract: Major depressive disorder (MDD), a globally discussed mental health condition, has drawn significant attention because of its unique and intricate nature. This is marked by the enduring presence of negative emotions stemming from a lack of interest, diminished self-esteem, and excessive rumination. Despite the widespread availability of various antidepressant medications, their effectiveness is hindered by low response rates, prolonged treatment durations, and the prevalence of side effects, such as headaches, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 54–62 Read article
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Morinda citrifolia Leaf Induced Leukemia Cells Apoptosis and Produced Synergistic Effects with Zerumbone
Abstract: Leukemia is the most common cancer among children and the 7th most common cancer worldwide. The vegetable Morinda citrifolia leaves was investigated and compared with Zerumbone (a known anti-leukemia compound) separately and in combination, for their apoptotic effects on murine myelomonocytic leukaemia cell line (WEHI-3B). Zerumbone, a sesquiterpene from Zingiber zerumbet was anti-cancer via suppressing free radical generation, inflammation, cancer cell proliferation, metastasis, anti-apoptosis, NF-κβ, Iκβα kinase activation and invasion. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 3, 2016 · pp. 24–32 Read article
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A Brief Review On Nanoparticles Drug Delivery System Used In Cervical Cancer
Abstract: Among cervical tumor-related deaths worldwide, cervical cancer is a major cause. The limitations of traditional methods, such as chemotherapy and radiation therapy, stem from their adverse effects and increased susceptibility to medications. Despite being seen as innovative options, immune checkpoint inhibitors (ICIs) have rather low clinical response rates. Reliable treatments for patients with metastatic or recurring cervical cancer are currently lacking. Lately, nanomaterials including polymers, liposomes, and dendrimers have been …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 30–40 Read article
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Biochemical Estimation of Allaxon Induced Hyperglycemia in Rats Treated with Polyherbal Preparation of Two of Indian Medicinal Plants Cordia Myxa and Canscora Diffusa
Abstract: A systematic study was conducted on extracts of Cordia myxa and Canscora diffusa to evaluate their qualitative chemical composition, phytochemical content, and antidiabetic activity. Then the Poly herbal extract is prepared with the selected plant powders, subjected to acute-toxicity studies for dose fixation. The herbal extracts formulation was prepared taking three selected dosages. The preparations are evaluated for anti-diabetic activity using Steptozotocine and Alloxan induced diabetic models in rats. The …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 52–60 Read article
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A Review on Formulation and Evaluation of Herbal Toothpaste from Anacyclus Pyrethrum Leaves Extract
Abstract: The main object to provide a formulation useful as natural herbal tooth paste which obviates the drawbacks of the earlier tooth pastes. And it’s to provide a good tooth paste which can give effective protection to teeth and free them from any toxicity or toxic residue and irritation when regularly used. Toothpaste is paste used with toothbrush to maintain and improve oral health and aesthetic. Anacyclus pyrethrum which is used …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 2, 2023 · pp. 6–12 Read article
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Histopathological Effects of Silver Nanoparticles on Gills and Liver of Freshwater Fingerlings Catla catla (Ham.)
Abstract: Fish is the best biomarker to identify the adverse effect on surroundings. Here, the fingerlings of major carp (Catla catla) were used as a model in the present work to investigate the toxicity caused by silver nanoparticles (AgNPs). The fish exposed to different concentrations of 10 μg/L and 30 μg/L AgNPs for 15 days were sampled at days 5, 10 and 15 for histology. This exposure caused organ injuries, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 1, 2016 · pp. 18–27 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Microbial Flocculants and Its Application in Wastewater Treatments: A Review
Abstract: Abstract Scarcity of water resources has compelled to develop techniques for effective wastewater treatments and reutilization of it. Industrial and municipal wastewaters are the biggest pollutants of natural water resources. Wastewaters from these sources are rich in suspended particles, dyes, toxic organic chemicals, heavy metals and nutrient content such as nitrogen and phosphorus. The removal of these chemicals and particles is biggest challenge for effective wastewater treatment and its disposal. …
Published in Journal of Water Pollution & Purification Research · Vol. 3, Issue 1, 2016 · pp. 42–50 Read article
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Unani Medicine Uncovered: Core Concepts And Quality Evaluations
Abstract: Unani medicine, a traditional healing system primarily reliant on herbal remedies, finds its roots in the ancient wisdom of Greek philosopher Hippocrates (460–377 BC) and his associates. Its evolution and prominence, however, owe much to the support of Persian and Arab empires before making its way to the Indian subcontinent around the mid-14th century. Unani practitioners believe that each individual possesses a unique temperament shaped by the interplay of four …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 10–17 Read article
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A Comprehensive Review on Pharmacological Properties of Coumarins
Abstract: Coumarins are a diverse group of secondary metabolites found in a variety of plant species (over 1200 different coumarins have been identified from natural sources, especially plants), as well as in fungi and microorganisms. Coumarin is a simple, widely occurring chemical structure in nature, present in many plants, fungi, and bacteria. In recent years, these natural compounds have attracted growing interest from the scientific community due to their broad spectrum …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 12–17 Read article