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252 articles for “Systems Biology”
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Insilico Structural Analysis and Homology Modeling of Crustin Protein from Fiddler Crab Species
Abstract: In terms of biomass and ecological or economic importance, the crustacea are the largest, most noticeable, and possibly, the most significance group of marine or aquatic arthropods. Because of their enormous commercial value and the necessity to prevent disease outbreaks in the shellfish aquaculture industry, decapods are the experimental animals of choice for practically all biological studies involving immune responses. Antimicrobial host-defense peptides (AMPs) are major components of metazoan immunity, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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Synthesis and Characterization of PF-127 Stabilized Metformin Encapsulated Chitosan-TPP Nanoparticles
Abstract: Metformin is widely used to manage Type 2 Diabetes, but its effectiveness is limited by low intestinal absorption, high dose requirements, and a short half-life. To tackle these challenges, several nano-drug delivery systems have been designed to optimize the delivery of metformin and enhance its therapeutic efficacy. Nanoparticles (NPs) have emerged as key players in medicine, biology, and pharmacology, gaini considerable attention for their potential applications. Polymeric NPs are among …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 34–38 Read article
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Floating In-Situ Gel for Gastric Retention Delivery
Abstract: When taken orally, medications with a limited window of absorption in the gastrointestinal tract (GIT) are typically accessible to the extremities due to the partial release of the active component and the brief residence period at the absorption site. Because they prolong the duration of the drug's presence in the stomach, they are made with high density and have the capacity to swell. Because oral fluids go more quickly through …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 24–32 Read article
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Liposomes Innovative Role as a Drug Delivery System: A Detailed Analysis
Abstract: The first nanomedicine to be approved for use in clinical settings was liposomes. These are the spherical vesicles with a bilayer of phospholipids enclosing a middle empty aqueous region. Because of their extraordinary potential to stop medication deterioration and lessen unwanted effects, liposomes are being utilized more and more for targeted drug distribution. For targeted drug delivery, the pharmaceuticals can be integrated into the liposomes' aqueous space or phospholipid bilayer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 25–32 Read article
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Phytoremediation of Aquaculture Wastewater: Duckweed (Lemna minor L.) as a Phytoremediator
Abstract: Aquaculture systems discharge huge quantities of waste into the aquatic ecosystem, in the form of excretory products and excess feed. These have grave implications on physicochemical and biological quality of the receiving environment. The study aimed to determine potential of duckweed (Lemna minor L.) for phytoremediation of aquaculture effluent. Hundred grams (100 g) of duckweed was grown in 10 L aquaculture effluent for 7-, 14-, 21-, and 28-day retention period …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 1, 2025 · pp. 13–19 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Synthesis, spectroscopic, crystal structure, Hirshfeld surface, computational, and biological investigations on Isophorone derivatives: 3-(3,4-dimethoxystyryl)-5,5-dimethylcyclohex-2-en-1-one
Abstract: FT-IR, 1H NMR, and 13C NMR spectroscopy were among the spectroscopic methods used to synthesize and analyze 3-(3,4-dimethoxystyryl)-5,5-dimethylcyclohex-2-en-1-one, a new isophorone derivative. Single-crystal X-ray diffraction (SCXRD) was used to determine the crystal structure, which showed that the molecule crystallizes in a monoclinic system (space group P121/c1) with packing configurations and intermolecular interactions. To learn more about the non-covalent interactions influencing the crystal packing, Hirshfeld surface analysis was used. In order …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 51–69 Read article
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Graphene–Perovskite Hybrid Opto-Electronic Modulators for Ultra-Low Power Optical Communication
Abstract: This paper proposes a novel self-adaptive neuromorphic opto-electronic transceiver architecture designed to enhance the intelligence, adaptability, and efficiency of next-generation optical communication networks. The proposed system integrates neuromorphic computing principles with photonic signal processing to enable real-time learning, dynamic resource allocation, and autonomous compensation of channel impairments such as dispersion, nonlinearities, and noise. Unlike conventional transceivers, the developed model employs spiking neural networks embedded within opto-electronic circuits to mimic biological …
Published in Trends in Opto-electro & Optical Communication · Vol. 16, Issue 1, 2026 · pp. 41–52 Read article
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Application of Resource Allocation Similarity Based Link Prediction in Wireless Networks
Abstract: Link prediction in wireless networks plays a crucial role in predicting missing connections within multiplex networks. This study focuses on the utilization of similarity-based link prediction methods in wireless networks. These methods assume that the likelihood of linkage between nodes is determined by their similarity, based on shared features. Several similarity measures, such as Common Neighbors (CN), Preferential Attachment (PA), Adamic-Adar (AA), and Resource Allocation (RA) indices, are commonly employed …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 2, 2023 · pp. 37–42 Read article
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AI-Driven Precision Nutrition: Advancing Personalized Dietary Systems for Public Health Equity in Resource-Constrained Environments
Abstract: The dual burden of malnutrition and diet-related non-communicable diseases (NCDs) represents a growing global public health challenge, particularly in low- and middle-income countries. Traditional dietary guidelines are largely population-based and fail to account for individual variability in genetics, metabolism, lifestyle, and environmental exposure. This limitation has led to the emergence of precision nutrition, an evolving field that integrates biological data and computational intelligence to deliver personalized dietary recommendations. This paper …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 Read article
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In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
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Revolutionizing Drug Delivery: Recent Advances in Pharmaceutical Dosage Forms
Abstract: Recent advances in pharmaceutical dosage forms revolutionize drug delivery, prioritizing targeted therapy and patient well-being. Enhanced drug carriers address complex medical challenges, from high-grade gliomas to ocular drug delivery, maximizing therapeutic efficacy while minimizing adverse effects. Traditional dosage forms like tablets and capsules undergo meticulous formulation and manufacturing processes, integrating Quality by Design principles for consistent product quality. Liquid formulations encounter stability challenges, necessitating rigorous stability testing and pH monitoring. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 77–89 Read article
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Alcohol, Circadian Glymphatic Dysfunction, and Neurodegenerative Protein Accumulation: An Emerging Concern in the Indian Context
Abstract: Alcohol consumption has long been identified as a major public health issue, yet its deeper and more subtle effects on the human brain are only now coming into sharper focus. Traditional explanations often emphasize direct neuronal damage, but emerging research in neuroscience suggests a more intricate story. Recent findings indicate that alcohol not only harms brain cells but also disrupts the body’s internal biological clock—the circadian rhythm—which plays a critical …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 1–4 Read article
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Recent Advancements in High-Performance Liquid Chromatography: A Comparative Approach
Abstract: Modern separation science relies heavily on chromatography, which is used in all research institutes and pharmaceutical industries all around the globe. Of all the chromatography approaches, HPLC i.e. high performance liquid chromatography is the one that is most frequently used analytically. Recent improvements in chromatographic supports and liquid chromatography (LC) equipment have made rapid and incredibly effective separations possible. This summary emphasizes the key milestones and foundational advances in HPLC …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 40–48 Read article
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Microorganisms used in aquaculture
Abstract: Microorganisms play a vital role in the health and sustainability of aquaculture systems, contributing to water quality management, disease control, and the overall productivity of aquatic farms. Beneficial microorganisms, including bacteria, fungi, algae, and probiotics, are increasingly recognized for their positive impact on aquaculture operations. These microorganisms can enhance nutrient cycling, promote the breakdown of organic waste, and reduce the need for harmful chemicals, thus improving the environmental footprint of …
Published in International Journal of Marine Life · Vol. 2, Issue 2, 2025 Read article
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Human Exploration of Mars: Challenges and Prospects for Sustainable Presence
Abstract: Human goals to Mars signify one of the most ambitious aims of present space exploration. While robotic missions have considerably extended our knowledge of the Martian atmosphere, sending humans to Mars proposes an extensive range of difficult hardships that must be tackled before such missions can become a reality. This review paper examines the most significant technical, biological, psychological, and logistical challenges associated with human exploration of Mars. The most …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 15, Issue 2, 2026 Read article
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Microbial Symphony: Understanding Biochemical Pathways for Precision Medicine and Beyond
Abstract: The human microbiome, an intricate ecosystem of microorganisms inhabiting the body, is a key regulator of host biochemistry and physiology. This review delves into the complex biochemical pathways influenced by the microbiome, spotlighting critical metabolites like short-chain fatty acids, bile acids, and tryptophan derivatives, which impact immune regulation, energy metabolism, and neurobehavioral functions. By examining interactions between the microbiome and the host, including the influence of genetic factors and metabolite-driven …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 28–43 Read article
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Participatory Demonstration of Desho and Elephant Grass Strip as Biological Soil and Water Conservation Measures for Erosion Control
Abstract: Participatory demonstration and pre scaling up of biological soil conservation measures (desho andelephant grass)compared with control (without grass) works were conducted in 2011/12 E.C on three beneficiary farmers field by the main objective is contribution of biological conservation measures for controlling soil erosion and assessing farmer perception on these measures. The data were taken from 132 m2 trail area. Average soil loss data that were obtained from Elephant grass 6.6 …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 13, Issue 2, 2024 · pp. 01–08 Read article
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Pain Management Through Ayurvedic Tablets and Capsules
Abstract: Triphala Guggulu is a classical formulation widely used in Ayurveda for the management of metabolic and inflammatory disorders. It represents a synergistic combination of Triphala – composed of Emblica officinalis, Terminalia bellirica, and Terminalia chebula – along with the oleo-gum resin of Commiphora mukul. In traditional Ayurvedic practice, this formulation has been prescribed for conditions, such as arthritis, obesity, hyperlipidemia, and chronic constipation, primarily due to its reputed ability to …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 23–28 Read article
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Interrelationship Between Psychological Stress and Gastrointestinal Physiology: Role of the Gut–Brain Axis
Abstract: The relationship between stress and gut microbiome is a critical area of medical research underscoring the relativity and impact of psychological and emotional states on gastrointestinal (GI) health. This paper investigates the intricate relationship between stress and digestive health by analysing the influence of stress hormones, gut–brain interactions, and psychosocial determinants. Both acute and long-standing stress responses may disrupt normal gastrointestinal activity, affecting motility, secretion, intestinal microbiota, and overall digestive …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article