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191 articles for “Pharmaceutical activities.”
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Current Trends in Crossing the Blood–Brain Barrier: A Review
Abstract: The blood-brain barrier (BBB) is a protective barrier that protects the central nervous system (CNS) from toxins and pathogens in the blood. However, the existence of BBB challenges therapy for CNS diseases and disorders as most pharmaceuticals (drugs) are restricted to enter brain. The review article focuses on the approaches involved to cross BBB with various advanced technology such as nanoparticles, intraventricular injection, chemical modifications, virus mediated distribution, exosome mediated …
Published in Trends in Drug Delivery · Vol. 10, Issue 2, 2023 · pp. 25–38 Read article
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A Review Study on Phytochemical and Pharmacological Aspects of Berberis asiatica Roxb. ex DC.
Abstract: Berberis asiatica, belongs to family Berberidaceae, is commonly known as Asian barberry or Kilmora. The plant is widely distributed in Himalayas. Research evidences support its use in various traditional medicinal formulas. Properties like antimicrobial, antidiebetic, anticancerous etc. have been reported in this plant. This review aims to highlight a comprehensive account of phytochemical constituents and pharmacological activities along with traditional uses in a view of many recent findings and its …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 2, 2020 · pp. 8–15 Read article
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Implications from Mesomaterials: Recent Trend
Abstract: Mesomaterials are materials of larger surface area, specific pore volume, more active chemical sites and high chemical stability. Mesoporous materials are used for molecular filtration and separation by adsorption of chemicals. Mesomaterials remove pollutant, toxic, and carcinogenic compounds from medium by interfacial adsorption-physisorption-chemisorption process. Molecular filtration on other hand is studied from categories produced by nano-maso-composed forms like silanol. Adsorption heat pump is operated by waste heat of solar energy. …
Published in Emerging Trends in Chemical Engineering · Vol. 7, Issue 3, 2020 · pp. 17–22 Read article
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Role of Neuropeptides in the Treatment of Major Depression Disorder: The Recent Updates
Abstract: Revelation of the part of neuropeptides as signaling atoms within the nervous system raised trust within the pharmaceutical field approximately 25. long time back Many neuropeptides, especially CRH, AVP, and substance P . whose receptors are presently focused on by little atoms to diminish side effects of discouragement and uneasiness, shows up to be related to the improvement and movement of temperament disarranges trouble. Neurotrophins, not exactly neuropeptides, may also …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 1–12 Read article
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Use of AI Tools to Create New Drugs
Abstract: The emergence of artificial intelligence in pharmaceutical research [in drug discovery] is a revolution in pharmaceutical research, often combining computational methods with traditional research methods to solve problems. This review article describes various applications of artificial intelligence at various stages of drug development and highlights significant advances and approaches. He explores the critical role of intelligence in drug design, polypharmacology, drug synthesis, drug repurposing, and prediction of drug properties, such …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 22–49 Read article
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Abresham (Bombyx mori Cocoon): A House of a worm with Immense Medicinal Value
Abstract: Abresham is the cocoon shell produced by an insect Bombyx mori (silk worm). Silk worm is mainly depend on mulberry leaves and spun cocoon of silk filament around it. In Unani System of Medicine (USM), this cocoon is known as Abresham Kham and when cut into small pieces before roasting then it is termed as Abresham Kham Muqarraz. It is one of the most common animal origin drug used in …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 30–41 Read article
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The Art of Drug Design and Process Chemistry
Abstract: The creation of safe and efficient medications depends heavily on the art of drug design and process chemistry. This multidisciplinary discipline designs and optimizes drug candidates for therapeutic uses by fusing the concepts of biology, chemistry, and engineering. Researchers can develop compounds with pharmacological activity by using logical drug design techniques if they have a thorough understanding of the molecular targets implicated in disease pathways. By making it easier to …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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Dr.JRK’s NIKU for the Management of Diabetes Mellitus
Abstract: NiKu was studied for its activity on alpha amylase and alpha glycosidase enzymes. The activity of both these enzymes got hindered by NIKU++. Then the NIKU was evaluated in human volunteers to understand its effect on blood glucose and the feeling of hunger. The study has clearly shown that NIKU is very effective in controlling the blood glucose for which the findings are presented in this paper. NIKU++: Siddha medicine …
Published in Research and Reviews: A Journal of Medicine · Vol. 7, Issue 3, 2017 · pp. 25–28 Read article
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Fundamentals and Recent Advances in Microreactor Catalysis and Flow Chemistry
Abstract: The processing technology of chemical reactions has changed quite a bit over the last few decades. For a long time, chemists relied on batch reactors having large containers where all the starting materials are mixed, and the reaction happens in one go. While this approach works, it has several drawbacks: poor heat control, uneven mixing, safety risks, and a lot of waste. Microreactors and flow chemistry offer a much better …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 2, 2026 · pp. 07–18 Read article
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Development and Evaluation of Cost Effective Formula of Nintedanib Esylate Soft Gelatin Capsule and Compare with Prepared Product Similar to Innovator
Abstract: Nintedanib esylate was invented by Boehringer Ingelheim Pharmaceuticals. Nintedanib esylate is an organosulfonate salt obtained by combination of Nintedanib with ethane sulfonic acid. It’s a kinase inhibitor used for the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. Bioavailability and water solubility of Nintedanib esylate is very low and BCS class is not mentioned in the literature. Due to poor solubility of Nintedanib esylate at neutral conditions, the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 3, 2018 · pp. 1–8 Read article
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Nano- Catalysts for Enhanced Performance in Hydrogenation Reactions
Abstract: The development of nano-catalysts has revolutionized the field of hydrogenation reactions, offering unparalleled efficiency and selectivity. This study explores the synthesis, characterization, and application of novel nano-catalysts designed to enhance hydrogenation processes. By leveraging advanced materials science techniques, we have engineered catalysts with precisely controlled particle sizes, shapes, and surface properties. These nano-catalysts exhibit remarkable activity and stability, attributed to their high surface area-to-volume ratios and unique electronic structures. Our …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 1, 2024 · pp. 22–27 Read article
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Ludiflash—A Novel Excipient for Patient Friendly Dosage Form
Abstract: Consumers want a pleasant-tasting and fast-acting tablet that can be taken anywhere, anytime without the need of water. They want such a tablet that completely disintegrates within moments, with no bitterness or chalky aftertaste. FDTs fast disintegrating tablets are the dosage form which will disintegrate in mouth within seconds without need of water. This type of property in dosage form can be attained by addition of different varieties of excipients. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 2, 2017 · pp. 5–7 Read article
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Biotherapeutic Antibacterial Activity of Some Medicinal Plants Against Predominant Bacteria Causing Dental Caries
Abstract: Dental caries is a microbial disease of the calcified tissues of the teeth, characterized by demineralization of inorganic portion and destruction of the organic substance of the tooth. It is most prevalent chronic disease affecting the human race. The in vitro antibacterial activity of some medicinal plants was studied against pathogenic bacteria causing dental caries. Leaves were extracted using petroleum ether, chloroform, acetone, methanol and distilled water. Among the five …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 2, Issue 1, 2012 · pp. 11–15 Read article
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A Review Article on Impact of Clinical Pharmacy Over Indian Health Care System
Abstract: Clinical pharmacy has its origins in hospital pharmacy, but in some countries, clinical activities which were restricted to hospitals in the beginning, are now well developed within the community setting. Clinical pharmacy practice in the hospital and community settings, as seen in other countries, can improve the drug use process by promoting the quality and safe use of medicines. India is a country with many drug use problems, as a …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 2, 2023 · pp. 1–5 Read article
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Microsphere and Nanoparticle Drug Delivery Systems: Role of Polymers in Pharmacology
Abstract: Microsphere and nanoscale drug delivery methods have changed the field of pharmacology by making treatment agents more bioavailable, more targeted, and easier to manage. These delivery systems, which are mostly made up of polymers, look like a good way to get around the problems that traditional drug formulations have, like not dissolving well, clearing quickly, and spreading in different places. Plastics are very important in the creation of these improved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 420–432 Read article
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Impact of Various Front-line Hypertensive medication on Blood Pressure Control During Maximum Exercise Testing in Coronary Artery Disease Patients
Abstract: It has long been known that blood pressure (BP) and cardiovascular morbidity are related. It is acknowledged that blood pressure during activity may serve as a more reliable indicator than resting blood pressure, which might not accurately reflect blood pressure at other times. Goals: 1) To assess how blood pressure behaves during physical activity in individuals with coronary artery disease (CAD) whose hypertension is managed with first-line antihypertensive medications. 2) …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 37–41 Read article
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Antibacterial Activity of Pongamia pinnata Leaf and Callus Extracts against Microorganisms Causing Periodontal Diseases
Abstract: Some specific microorganisms have been identified as etiologic agents of periodontitis. The main goal of treatment is to control the spread of infection. Depending on the extent of the gum disease, treatment varies. Therapeutic antibiotic along with surgery are the most opted form of treatment. But, due to high costs of antibiotics, the disastrous side effects and emergence of multi drug resistant strains of these pathogenic bacteria, a safe alternative …
Published in Research and Reviews: A Journal of Dentistry · Vol. 3, Issue 2, 2012 · pp. 1–7 Read article
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Comparative Evaluation of Physical, Chemical and Antimicrobial Properties of Mercury and Cinnabar
Abstract: Herbo-mineral preparations have a special and significant role to play in the system of Ayurveda. These formulations include many of the metals viz., mercury, lead, arsenic etc., which are considered highly toxic by the modern concepts of medicine. These formulations have been compared to that of the environmental toxicity caused by many contaminants leading to severe health hazards. However, there is strong reasoning given by the traditional practices which incorporate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 3, 2019 · pp. 9–23 Read article
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Exploring the properties and extraction of neem leaves
Abstract: Neem (Azadirachta indica) is a versatile medicinal plant, for its diverse therapeutic properties. This abstract provides a comprehensive overview of recent research focusing on phytochemical analysis, biochemical characterization, and antimicrobial susceptibility testing of Neem extracts. Utilizing the different from of chemical used in it, phytochemical analysis identified a plethora of secondary metabolites within Neem, including alkaloids, flavonoids, terpenoids, steroids, saponin, tannins, quinone, and phenolic compounds, indicative of its complex chemical …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 32–39 Read article
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Assessment of Antibacterial Potentialities of Diacetaldehyde Terpenoid Isolated from Curcuma Caesia Roxb. Against a Panel of Pathogenic Bacteria
Abstract: Assessment of antibacterial potentialities of a diacetaldehyde terpenoid was performed in this paper against a panel of pathogenic bacterial strains. This terpenoid was isolated from Curcuma caesia Roxb. and found to have several kinds of biological activities like antibacterial, antifungal and antitumour. In this experiment it was found that the terpenoid can inhibit the growth of bacterium at 150 to 200 μg/ml of concentrations. Hence, this terpenoid can be used …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 13–16 Read article