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220 articles for “Multi-targeted”
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Emerging Therapies for Diabetes Mellitus: Efficacy and Safety of USFDA-Approved Drugs and Late-Stage Clinical Trials
Abstract: This review provides a comprehensive analysis of drugs approved by the U.S. Food and Drug Administration (USFDA) for managing diabetes mellitus (DM) from 2013 to 2022, including emerging treatments from phase 3 clinical trials during this period. Over the past decade, the treatment landscape for diabetes has evolved significantly, with new therapies not only improving blood sugar control but also targeting broader health outcomes like heart and kidney health. In …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 11–23 Read article
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Application of Drug Delivery using Nano- technology to Cure Mental Disorders (Schizophrenia)
Abstract: Nanotechnology involves the manipulation of the count at an atomic scale to create novel systems, materials, and devices. This groundbreaking era holds substantial potential for scientific development across various domain names, which includes manufacturing, patron items, electricity, substances, and remedies. In current times, the sphere of prescribed drugs has witnessed a brilliant surge in the usage of nanotechnology for the improvement of revolutionary medications. Schizophrenia, a neuropsychiatric disorder affecting the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 51–65 Read article
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Periodontitis and Rheumatoid Arthritis
Abstract: This comprehensive review delves into the complex interplay between Periodontitis and Rheumatoid Arthritis, aiming to unravel the underlying mechanisms and shared inflammatory pathways that connect these seemingly distinct conditions. The review examines a wealth of current research, exploring how chronic periodontal inflammation may contribute to the development and progression of RA and vice versa. Furthermore, the review critically evaluates the clinical implications of this interrelation, emphasizing the need for interdisciplinary …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 31–39 Read article
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Intelligent Paradigms in Subsea Connectivity: A Comprehensive Review of Artificial Intelligence in Underwater Communications
Abstract: Underwater wireless communication (UWC) plays a critical role in ocean exploration, environmental monitoring, offshore energy operations, disaster management, and naval defense. However, the underwater environment presents significant communication challenges, including severe signal attenuation, multipath propagation, Doppler effects, limited bandwidth, high latency, and energy constraints. Recent advancements in Artificial Intelligence (AI) and Machine Learning (ML) have emerged as promising solutions to address these limitations and enhance the efficiency, reliability, and adaptability …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 3, 2025 Read article
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Impact of Groundwater Pollution on Carcinogenic and Non-Carcinogenic Health Effects: A Review
Abstract: Groundwater is a critical source of drinking water in many regions worldwide, particularly in South and Southeast Asia, where dependence on untreated groundwater remains high. However, increasing groundwater contamination poses serious risks to human health. This review synthesizes recent peer-reviewed studies to examine the sources, distribution, and health impacts of major groundwater contaminants, with a focus on both carcinogenic and non-carcinogenic risks. Emphasis is placed on fluoride, nitrate, chromium, and …
Published in Research & Reviews : Journal of Ecology · Vol. 15, Issue 1, 2026 · pp. 40–46 Read article
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Constrained Online Non Negative Matrix Factorization (CONMF) for Visual Tracking
Abstract: Visual tracking is the process of locating a moving object (or multiple objects) over time using a camera. It is one of the most important components in numerous applications such as military, secure control, crime prevention systems, access control and biometric identification etc. of computer vision. In visual tracking, holistic and part-based representations are both popular choices to model target appearance. The former is known for great efficiency and convenience …
Published in Current Trends in Signal Processing · Vol. 7, Issue 1, 2017 · pp. 8–18 Read article
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Multitarget Molecular Docking Using Curcuma longa Phytocompounds for Polycystic Ovary Syndrome Treatment
Abstract: Objective: The primary goal of this research is to understand and describe specific aspects of molecular interaction, it includes studying various aspects such as binding affinity, binding mode, and stability of the ligand-protein complex. Molecular docking is a computational technique used to predict the preferred orientation of one molecule to a second when bound together to form a stable complex. In this study, molecular docking will be employed to stimulate …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 15–28 Read article
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PG- Life Management System
Abstract: Multiple Sclerosis is an autoimmune disorder mostly affecting individuals aged between 20-40. In this disorder, the optic, vertebral, and central nervous system nerves are primarily impacted. It is a neurological condition that worsens over time and is characterized by inflammation and the breakdown of the sheath that surrounds and shields the nerve fiber. Common symptoms may include muscle weakness, numbness, tingling, fatigue, vertigo, tremor, vision complications, pain, Lhermitte sign, sexual …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Quantum Mechanics: Revolutionizing Pharmaceutical Sciences
Abstract: Quantum physics and pharmacy have generally been regarded as distinct areas—one investigates the microlevel behavior of non-living matter while the other concentrates on intricate biological systems. Nevertheless, progress in life sciences has increasingly depended on molecular-level insights, whereas quantum physics has advanced beyond basic principles to impact real-world uses. This intersection provides new opportunities for, pharmacy. Quantum entanglement, which allows for instantaneous relationships between particles, can be utilized for secure …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 72–77 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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The Power of Persuasion: How Social Engineers Exploit Social Media Dynamics
Abstract: Social engineering, the strategic manipulation of individualities through cerebral tactics, thrives on social media platforms, where specific dynamics enhance its impact. This study delves into the styles social masterminds employ to exploit social media, assaying common strategies like phishing, impersonation, misinformation, and emotional prayers. Social media provides rich ground for these tactics through features similar as algorithmic modification, stoner obscurity, and echo chambers, which allow social masterminds to reach and …
Published in Journal Of Network security · Vol. 13, Issue 1, 2025 · pp. 37–44 Read article
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Numerical Simulation of Hybrid GSA Based Optimal Power Flow for Multi Objective Optimization Strategy
Abstract: Restricted nonlinear optimization in electric power systems engineering is a topic of Optimal Power Flow (OPF) that has been extensively investigated. It has been a long and remarkable history for the OPF, which was founded in the 1960s, of research and publication. Newcomers to OPF research face a challenging undertaking since there is so much information available and because OPF's popularity within the electric power systems community has prompted authors …
Published in Journal of Instrumentation Technology & Innovations · Vol. 11, Issue 3, 2021 · pp. 24–32 Read article
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Examining the role of banks in financing nuclear power programs for a green economy and clean energy transition
Abstract: Nuclear power programs have the potential to contribute to deep, multi-sector and economy-wide decarbonization as sources of reliable, low emissions intensity thermal and electrical energy. However, nuclear power projects are complex, capital-intensive ventures with significant financial risks associated with them. Therefore, financing has been a critical issue for these projects. To accelerate their deployment to meet clean energy transition targets of nations and institutions, financial institutions like banks can play …
Published in Journal of Nuclear Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 28–39 Read article
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Greener 3D Printing: The Role of Artificial Intelligence in Sustainable Polymer and Composite Manufacturing
Abstract: The integration of sustainable materials with additive manufacturing (AM) technologies marks a significant step towards environmentally responsible production. Biodegradable polymers, recycled thermoplastics, and bio-based composites, when used in 3D printing, offer the potential to reduce the ecological footprint of manufacturing. However optimizing the interplay between material properties process parameters, and product performance remains a complex challenge. This review examines how artificial intelligence (AI) is being applied to address these challenges …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 288–300 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Heterosis in Plants
Abstract: It refers to hybrid vigor or heterosis; herein, the offspring expressed better traits than one or both parent lines. This most often manifests in crop breeding as increased yield in F1 hybrids compared with their parents. Developing high-yielding hybrid cultivars across a wider range of crops represents an important strategy for addressing future food security. However, conventional hybrid breeding approaches are fraught with significant challenges in many self-pollinating crops, such …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 2, 2025 · pp. 21–31 Read article
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Innovations in Tuberculosis Management: Advancements in Drug-Resistant TB Treatment and Rapid Diagnostics
Abstract: Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, exacerbated by the increasing prevalence of drug-resistant strains, such as multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB). Despite advancements in first-line and second-line treatments, resistance to conventional antibiotics has complicated therapeutic strategies, necessitating novel approaches. This mini review explores emerging advancements in TB treatment, including gene editing technologies, such as CRISPR, which offer potential for precise targeting of drug-resistant bacterial …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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Quantitative Mass Balance Modelling for the Synthesis and Production of Ten High-Volume Insecticides
Abstract: This study presents a detailed quantitative mass balance analysis for the industrial synthesis and production of ten high-volume insecticides: acequinocyl, acetamiprid, acynonapyr, alpha-cypermethrin, benzpyrimoxan, bifenazate, bifenthrin, bistrifluron, broflanilide, and bromofos, focusing on material flows, process efficiencies, and environmental implications. These compounds, spanning diverse chemical classes like neonicotinoids, pyrethroids, and meta-diamides, are essential for crop protection but pose challenges due to resource-intensive syntheses and waste generation. For each insecticide, standardized manufacturing …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 36–55 Read article
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Exploring the Therapeutic Potential of Grapeseed Phytoconstituent Through Molecular Docking Analysis for Multiple System Atrophy Treatment
Abstract: Objective: Alpha-synuclein (α-Syn) aggregates are a common neurodegenerative disorder associated with Parkinson’s disease and multiple system atrophy (MSA). As a fruit that is extensively grown, grapes have several pharmacological advantages when it comes to reducing oxidative stress. Research has indicated that grape seed phytoconstituents have a major effect on α-Syn. The objective of this study is to inquire into the pharmacological characteristics and potential therapeutic applications of grape seed derivatives …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 14–26 Read article
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Impact of Training Program on Recent Innovations in Oncology Among Nursing Professionals
Abstract: Introduction: In recent years, there have been significant advancements and trends in the field of oncology treatment in India. This study aimed to evaluate impact of training program on knowledge regarding recent innovations in oncology among nursing professionals. After ethical approval, a pre-experimental, one group pretest- post-test design was used to conduct this research at anursing college of Punjab. Methods: The sample was selected using the total enumerative sampling technique. …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 9–14 Read article