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1949 articles for “DR” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Unlocking Potential: Capecitabine’s Evolution as an Anticancer Wonder Drug
Abstract: Capecitabine, a precursor to 5-fluorouracil (5-FU), is Anticancer Drug in treating solid tumors like colorectal, breast, and gastric cancers. Its mechanism involves converting to 5-FU mainly within tumor cells, reducing toxicity while maximizing effectiveness. Besides being effective alone, it is also valuable in combination therapies, showcasing its versatility in cancer treatment. This review explores the transformative journey of capecitabine as a pivotal anticancer drug. Beginning with an introduction to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
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Blockchain Technology for Strengthening the Indian Generic Medicine Supply Chain and Combating Counterfeit Drugs
Abstract: India is one of the leading distributors of generic medicines globally, but its supply chain faces numerous challenges including substandard medicines, counterfeiting, and inefficient logistics. Blockchain technology offers a promising solution by providing a secure, decentralized, and transparent platform to track and verify the entire drug supply chain from production to delivery. This paper investigates the potential of blockchain to mitigate counterfeit drug circulation, improve trust in Indian generic medicines, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 9–12 Read article
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Evaluation of Polysaccharide-Based Membranes for Transdermal Drug Delivery in Chronic Pain Management
Abstract: In order to improve treatment effectiveness and patient compliance, chronic pain management is still a major challenge in modern healthcare, requiring creative medication delivery methods. The potential of polysaccharide-based membranes for transdermal drug delivery is assessed in this work, with particular attention to chitosan, alginate, and hydroxypropyl methylcellulose (HPMC). Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were two characterization techniques used to assess the membranes' physical and chemical …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 28–38 Read article
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Using Artificial Intelligence for The Design of Polymeric Drug Delivery Systems
Abstract: AI is cost effective and time efficient process. Artificial intelligence is a method which uses high speed calculation, the improvement regarding algorithm along with collection about biological and chemical features in pharmaceutical exploration and development .Present day because continuous progress towards machine learning (ML),Artificial intelligence an effective statistics analysing technology might have been broadly utilized in drug design .In pharmaceutical exploration and research employ of AI in target identification, compound …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1018–1027 Read article
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Effect of Drilling Process Parameters on Surface Roughness of LM6/B4C/Fly Ash Hybrid Composites
Abstract: This research seeks to assess the effect of process variables such as feed rate (FR), spindle speed (SS), drill material (DM) and reinforcement (R%) on surface roughness (SR) when drilling LM6/B4C/Fly ash hybrid composites. The stir casting process was used to fabricate the LM6/B4C/Flyash hybrid composites utilizing LM6 aluminum alloy as the matrix material and B4C/Fly ash as strengthening materials. Experiments were carried out using an L18 orthogonal array (OA) …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 898–906 Read article
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Pharmacovigilance and drug safety current trends and challenges
Abstract: Pharmacovigilance and drug safety are critical areas of focus in healthcare, aimed at monitoring the safety and efficacy of pharmaceutical products throughout their lifecycle. This review explores current trends, emerging technologies, and challenges in pharmacovigilance, emphasizing their impact on public health and regulatory practices. With the increasing complexity of global pharmaceutical markets, pharmacovigilance systems are evolving to integrate real-time data analytics, artificial intelligence (AI), and machine learning (ML) to detect …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 19–27 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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The Reaction About Anti-Hypertensive Drugs According to Plasma Renin-Aldosterone States
Abstract: With recent studies, hypertension has not only a simple pathophysiology, thus it can classify details more about and establishing drug therapy strategies compatible with it is a very important method to improve the organ predictive of patients. The purpose of this study is to compare the responsibility of some anti-hypertensive drugs in hypertensive patients according to plasma renin-aldosterone levels, which becomes the background factor of hypertension. We investigated 71 hypertensive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 14–23 Read article
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Gene Drive Technology: Potential and Risks for Global Biodiversity
Abstract: Gene drive technology has emerged as a groundbreaking tool with significant potential to address critical global challenges, particularly in managing and preserving biodiversity. By enabling targeted alterations to the genetic makeup of species, gene drives could facilitate the control of invasive species, mitigate vector-borne diseases, and even aid in the restoration of endangered species. However, the rapid pace of development and deployment of gene drive technologies raises concerns about unintended …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 6–10 Read article
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Drone Safety Protocols Developing and Implementing Safety Procedures
Abstract: The increasing utilization of drones across various sectors, including agriculture, logistics, surveillance, and recreational activities, necessitates the establishment of robust safety protocols to mitigate risks associated with their operation. This study explores the development and implementation of comprehensive safety procedures for drone operations, focusing on both regulatory compliance and technological advancements. The study emphasizes how crucial it is to comprehend the legal frameworks set forth by aviation authorities, including the …
Published in International Journal on Drones · Vol. 1, Issue 1, 2025 · pp. 44–49 Read article
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A Study on Drone Hacking: Vulnerabilities and Mitigation Techniques
Abstract: This paper explores the current cybersecurity landscape surrounding Unmanned Aerial Systems (UAS), commonly known as drones. With rapid growth in commercial and recreational drone use, the risk of cyber-attacks has also increased. This study highlights real-world vulnerabilities such as GPS spoofing, Wi-Fi hijacking, and firmware exploitation. It also suggests practical mitigation techniques, including encryption, real-time anomaly detection using machine learning, and secure communication protocols. The goal is to support researchers, …
Published in International Journal on Drones · Vol. 1, Issue 2, 2025 · pp. 1–8 Read article
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Comprehensive Review on Pulsatile Drug Delivery System: Hybrid Approaches
Abstract: Pulsatile drug delivery systems (PDDS) represent a groundbreaking approach in pharmaceutical technology, allowing for controlled, targeted, and programmable drug release that aligns with circadian rhythms or caters to time-sensitive therapeutic requirements. Although traditional pulsatile systems have shown considerable clinical promise, their effectiveness is frequently compromised by physiological variations such as gastrointestinal transit times, changes in pH, and enzymatic activity. To tackle these obstacles, hybrid PDDS have been developed by combining …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 18–31 Read article
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In-Silico Repurposing of Antipsychotic Drugs Against Novel Protein Targets in Multidrug-Resistant Mycobacterium tuberculosis
Abstract: Multidrug-resistant TB is a growing worldwide health concern, particularly in high-burden areas. Resistance to frontline drugs like isoniazid and rifampicin is caused by mutations in key Mycobacterium tuberculosis proteins. Given the difficulty of developing new antibiotics, medication repurposing offers a good alternative. The potential use of molecular docking to target resistance-associated TB proteins with FDA-approved antipsychotic drugs is investigated in this work. Three proteins were selected: InhA (PDB ID: 5W07), …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 49–63 Read article
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Advancements in Buccal Patch Drug Delivery Systems: A Comprehensive Review of Evaluation Parameters
Abstract: The most dependable delivery method is buccal patches because it offers many improvements over alternative methods.This delivery method circumvents the hepatic first pass metabolism to deliver the medication into the systemic circulation. Buccal patches are inserted between the cheek and gums, where they dissolve and absorb through the buccal cavity's mucosal membrane. Polymers can be used to control the drug's delivery, and intelligent polymeric systems are a good option for …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 2, 2025 Read article
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Regression Analysis of Topological Indices and Physicochemical Properties of Polymer-Based Anticancer Drugs
Abstract: The research analyzed the quantitative correlation between topological indices and the physicochemical properties of selected anticancer compounds using regression analysis. Various topological descriptors—such as the First Zagreb Index, Second Zagreb Index, and Forgotten Index were calculated and regressed against key molecular features, including polar surface area, melting point, and molar refractivity. The regression analysis revealed linear correlations between these topological indices and the properties of anticancer drugs, with particularly strong …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 255–267 Read article
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A Data-Driven Analysis of Machine Learning Classification Models for Reliable Crop Yield Prediction
Abstract: The adoption of ML technologies in agriculture is reshaping farming practices, empowering producers to make informed, data-oriented decisions that improve yields, sustainability, and long-term resilience. In mango cultivation, ML analyzes data from weather, soil, and pests to optimize irrigation, fertilization, and pest control. Predictive analytics help forecast ideal farming practices, minimizing resource wastage and improving yield. Real-time monitoring and image-based disease detection allow timely interventions to maintain plant health and …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 15, Issue 1, 2026 · pp. 12–17 Read article
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The Future of Farming with IoT-Operated Drones
Abstract: The integration of Internet of Things (IoT) technology with drone systems has revolutionized precision agriculture, offering innovative solutions to address the inefficiencies and environmental concerns linked to conventional pesticide application. This study explores the design, implementation, and impact of IoT-operated drones tailored for automated pesticide spraying. By leveraging real-time sensor data, AI-driven analytics, and cloud-based connectivity, these drones enable dynamic, data-informed decisions to optimize chemical application. Results indicate that IoT-enabled …
Published in International Journal on Drones · Vol. 2, Issue 1, 2026 · pp. 20–26 Read article
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Signal Drift Compensation in Polymer-Based Wearable Biosensors Using Data Processing Techniques
Abstract: Polymer-based wearable biosensors have emerged as promising platforms for continuous physiological monitoring due to their mechanical flexibility, low operating voltage, and compatibility with soft biological interfaces. However, their long-term deployment remains challenging because of signal drift caused by polymer ageing, hydration–dehydration cycles, ionic trapping, and environmental variations. These effects introduce baseline fluctuations and sensitivity degradation, which compromise the reliability and interpretability of physiological measurements. This study proposes a data-processing–driven framework …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 197–207 Read article
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Effect of machining parameters on the tool wear in drilling of 3D PF C/C composite
Abstract: Carbon–carbon (C/C) composites are broadly used in aerospace, defence, shipbuilding, chemical, and nuclear industries owing to their high strength-to-weight and stiffness-to-weight ratios. However, they are brittle, anisotropic and non-homogeneous in nature, making them difficult to machine. Incorrect machining parameters can cause defects such as burrs, delamination, and fibre bundles pullout. This paper aims to study the hole surface and tool wear during drilling of 3D pierced fabric (PF) carbon-carbon (C/C) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 269–281 Read article