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206 articles for “ACE 2”
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Isolation, Phytochemical Investigation and Biological Screening of Roots of Cosmos Sulphureus
Abstract: Aims and objectives: The plants are integral part of traditional system of medicine. Cosmos is one such medicinal plant traditionally being used in Brazil and Mexico for treatment of several diseases. The present study is aimed to evaluate the properties of Cosmos sulphureus and its preliminary phytochemical screening, extraction, purification and identification of active components.Materials and Methods:All roots were handpicked and washed with tap water. Cleaned roots were air dried …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 10, Issue 1, 2023 · pp. 1–9 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Design, Synthesis, and in vitro Evaluation of Novel Benz/Imidazole-2-acetonitrile Derivatives as Antibacterial and Antifungal Agents
Abstract: Benzimidazole is a pharmaceutically important compound. In this research, we were able to prepare several heterocyclic derivatives from it by first preparing a new azo derivative ZH through a reaction of 3-aminoacetophenone with benzimidazole-2-acetonitrile. This azo derivative was then introduced via a condensation reaction with aromatic amine derivatives, resulting in the preparation of two Schiff base derivatives Z1 and Z2. From these bases, six and seven membered heterocyclic derivatives were …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 53–87 Read article
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Synthesis and Characterization of Sustainable, Low-Cost, Biomass-Derived Carbon Films from Hevea Brasiliensis (Rubber) Wood for Environmentally Friendly Gas Sensors with Enhanced Selectivity and Sensitivity to Polar Vapors and Hazardous Gases
Abstract: Hevea brasiliensis (rubber) wood sawdust was utilized to fabricate carbon gas sensors for detecting 1000 ppm of ethanol, methanol, acetone, carbon dioxide, and ammonia gases. The carbon particles were prepared by phosphoric acid impregnation followed by thermal activation and then fabricated into films on conductive and non-conductive substrates using the doctor blade method. X-ray diffraction (XRD) analysis revealed distinct graphitic features with peaks at the (002) and (100) planes, indicating …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 22–36 Read article
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A Mini-Review on Spectral (UV Visible, FT-IR, 1H NMR, GC-MS) Analysis of Various Shaded Dried Leaves Extracts
Abstract: To collect the different types of leaves in various places, wash collected leaves with distilled water and dried these leaves in various processes like under shade dry for 15 days, place oven (45 oC) for 1 hour. Grind well using the above-dried leaves, so these leaves are changed to powder form. Utilize these shaded dried leaves powder, to prepare extract with solvents like methanol, ethanol, hexane, carbon tetrachloride, petroleum ether, …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 13, Issue 1, 2022 · pp. 1–8 Read article
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Photochemically Assisted LC–MS Method Development and Validation for Stability-Indicating Determination of Glasdegib in Rat Plasma
Abstract: A simple, precise, and cost-effective LC–MS method was successfully developed for the determination of Glasdegib in rat plasma. The method optimization was carried out by systematically varying key chromatographic parameters, including flow rate, injection volume, analyte concentration, and mobile phase composition, to achieve optimal sensitivity and resolution. A C18 Hypersil BDS column (150 mm × 4.6 mm, 3.5 µm particle size) was used for chromatographic separation, offering effective peak shape …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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The effective therapeutic strategies to fight against COVID-19 in India
Abstract: In December 2019, the global pandemic coronavirus infection (COVID-19) was first detected in Wuhan, Hubei Province, Central China. It is caused by coronavirus-2, which causes severe acute respiratory syndrome (SARS-CoV-2). This was declared by World Health Organization on 11th March 2020. In India, the first case of COVID-19 infection was reported in Kerala on January 27,2020 of a 20 yr old female presented to an Emergency Department in General Hospital, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 12, Issue 1, 2022 · pp. 43–49 Read article
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Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article
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Quantitative Mass Balance Modelling for the Synthesis and Production of Ten High-Volume Insecticides
Abstract: This study presents a detailed quantitative mass balance analysis for the industrial synthesis and production of ten high-volume insecticides: acequinocyl, acetamiprid, acynonapyr, alpha-cypermethrin, benzpyrimoxan, bifenazate, bifenthrin, bistrifluron, broflanilide, and bromofos, focusing on material flows, process efficiencies, and environmental implications. These compounds, spanning diverse chemical classes like neonicotinoids, pyrethroids, and meta-diamides, are essential for crop protection but pose challenges due to resource-intensive syntheses and waste generation. For each insecticide, standardized manufacturing …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 36–55 Read article
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Green Synthesis of Biologically Active 2, 4, 5- Trisubstituted Imidazoles Catalyzed by Large Pore Zeolite H-BEA through Lophine MCRs
Abstract: 2, 4, 5-triphenyl-1(H)-imidazoles (popularly known as Lophine derivatives) are well known heterocyclic compounds and find significant diversified applications, not only in the area of medicinal chemistry as biologically active drug-like molecules, but also in the other advanced research areas, such as fluorescence labelling, biological imaging and chromospheres for non-linear optic system. In the present endeavour, a green synthesis of Lophine derivatives via multi-component reaction is carried out using benzil/benzoin, substituted …
Published in Journal of Catalyst & Catalysis · Vol. 4, Issue 3, 2017 · pp. 20–36 Read article
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Cysticercosis in a Wistar Albino Rat
Abstract: The present study was conducted to know the cause for multiple cysts in the liver of laboratory rat used for experimental purpose in research work. A male Wistar albino rat about 22 weeks of age showed the presence of numerous cysts in liver. The cyst along with normal liver tissue was collected in 10% of formalin and processed for histopathology. Gross examination of liver showed white to yellowish cyst of …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 6, Issue 2, 2017 · pp. 23–25 Read article
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Analysis of Radiographic Parameters Predisposing to Pain Following Total Hip Arthroplasty and Bipolar Hip Hemiarthroplasty
Abstract: Background: Persistent pain following total hip arthroplasty (THA) and bipolar hip hemiarthroplasty (BHHA) has been considered as a main source of patient dissatisfaction. The aim of this study is to determine the correlation between radiographic findings and painful total/partial hip arthroplasty.Materials and Method: One hundred sixty BHHA and one hundred forty-eight THA patients responded to a pain-diagram questionnaire and postoperative radiographic measurements of component positioning and bone morphology were performed …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 3, 2022 · pp. 6–14 Read article
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Grape Seed Extract: Potent Chemoprotective Agent: Phytochemical Analysis and GC-MS Study
Abstract: Plant extracts or secondary metabolites have served as antioxidants in phytotherapeutic medicines to protect against various diseases for centuries. Phytochemicals are naturally occurring in the medicinal plants, leaves, vegetables and roots that have defence mechanism and protect from various diseases. Phytochemicals are primary and secondary compounds. Chlorophyll, proteins and common sugars are included in primary constituents and secondary compounds include terpenoids, alkaloids, quinines, flavonoids, sterols, saponins, tannins and phenolic compounds. …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 5, Issue 3, 2016 · pp. 30–39 Read article
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Chemical Profile and Toxicity of Fresh and Dry leaves of the Essential Oils of Vetiveria zizanioides (L.) Nash. From Southwest Nigeria
Abstract: The fresh and dry leaves of Vetiveria zizanioides (L.) Nash (Gramineae) plant was collected, air dried and authenticated at the University of Ibadan Herbarium with voucher number: UIH-23237. The plant's dried, fresh leaves were hydro distilled in a Clevenger device to extract the essential oils. The oils were characterized by Gas Chromatography-Mass Spectrometry (GC – MS) while the toxicity of the essential oils was tested using brine shrimps’ lethality assay. …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 1, 2024 · pp. 44–49 Read article
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Pollen Biology and Stigma Receptivity in Nymphoides indica (L.) O. Kuntze (Menyanthaceae)
Abstract: AbstractNymphoides indica (L.) O. Kuntze an emergent aquatic plant of Menyanthaceae, commonly called ‘floating hearts” is bisexual, hypogynous and distylous (Two types of style – long style and short style) with 4 – 8 sepals and petals. Stamens correspond to the number of petals. The present study deals with phenology, pollen biology and stigma receptivity of N. indica. The pollen grains are yellow, medium, monad, triangular, heteropolar, radially symmetric, parasyncolpate …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 10, Issue 1, 2020 · pp. 72–80 Read article
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Characterization of Endofungus Aspergillus nomius EF8-RSM Isolated from Aloe vera Western Ghats of Karnataka India
Abstract: The objective of the present research investigation was to reveal the versatile nature of endophytic Aspergillus nomius EF8-RSM. The fungus was purified from Aloe vera, Western Ghats of Karnataka, India and sequence was submitted at NCBI under the accession number MN871698. The fungus successfully produced Indole acetic acid at the rate of 49.21±6.1 μg/ml and phosphate solubilization was confirmed with solubilization index (1.63). The fungus showed production of siderophore, ammonia …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 22–30 Read article
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Assessment of Indoor Air Pollutants with Special Reference to Particulate Phase Polyaromatic Hydrocarbon in Rural Villages
Abstract: Emissions from household stoves using traditional biomass fuels such as firewood, crop residue and animal dung could have a continuing contribution to air pollution and also have adverse health impacts due to emission of different toxic pollutants. The present study was carried out in 13 household kitchens in Thavarghatta located in Shimoga district to know the level of the total suspended particulate matter (TSPM) and particulate phase polyaromatic hydrocarbons (PAHs) …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 38–45 Read article
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In vitro Antibacterial Activity of Averrhoa carambola Leaf Extracts
Abstract: The aim of the present study was to determine the phytochemical constituents and antimicrobial potential of Averrhoa carambola leaf extracts against three gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus and Streptococcus mutans) and three gram-negative bacteria (Klebsiella pneumoniae, Proteus vulgaris and Pseudomonas aeruginosa) which are some of the infectious bacteria. The A.carambola leaves were extracted in three different solvents of increasing polarities (hexane, ethyl acetate, and acetone). The phytochemical analysis showed …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 8, Issue 2, 2018 · pp. 27–32 Read article
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Synthesis of Novel Sugar-Benzimidazole Derivatives
Abstract: Conversion of some unprotected and unmodified aldoses with o-phenylene diamine to aldo-imidazoles using iodine catalyst in acetic acid solution has been applied, according to a known method. Accordingly some novel derivatives have been synthesized. Characterization of the synthesized products has been performed by M.P., chromatography, IR and mass spectra. Keywords: Sugar-benzimidazole derivatives, IMs, carbohydrate labelingCite this Article Al-Difar Hussniya A, Basma Younis, Basma Saad Baaiu et al. Synthesis of Novel …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 2, 2017 · pp. 1–4 Read article
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Parametric Analysis on Pulsating Heat Pipes
Abstract: Day-by-day the size of the electronic components is being drastically decreased, but at the same time the computing capacities are improved manifold. This presents a new challenge in the thermal management of these components. Pulsating Heat Pipes (PHP) can transport warmth for considerable distances leading to placement of condenser away from compact cabinets. From the literature, it is observed that Acetone, Ethanol and Distilled water are the most widely used …
Published in Recent Trends in Fluid Mechanics · Vol. 4, Issue 1, 2017 · pp. 38–43 Read article