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1991 articles for “demonstration” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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DFT/Data Guided Predictive Modelling of Absorption Maxima in the OLED Rubrene Derivatives
Abstract: This study investigates the optical properties of rubrene derivatives to develop an accurate predictive model for absorption maxima using computational chemistry and chemoinformatic techniques. We benchmarked various quantum chemical methods, identifying that the M06-2X/aug-cc-pVDZ method in dichloromethane (DCM) provided the strongest correlation with experimental data. Key molecular descriptors such as band gap, ionization potential, and electrophilicity index were calculated and analyzed using principal component analysis (PCA) to identify significant factors …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 41–56 Read article
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Experimental and CFD Investigation of an Epoxy-Based Thermally Conductive Polymer Composite U-Tube Shell-and-Tube Heat Exchanger: A Lightweight Alternative to Conventional Metal Systems
Abstract: Shell-and-tube heat exchangers continue to play a critical role in industrial thermal systems; however, their conventional design based on fully metallic materials often leads to challenges related to weight, corrosion, and cost. In recent years, thermally conductive polymer composites have emerged as promising alternatives, offering improved corrosion resistance and design flexibility. In this study, the thermo-hydraulic performance of a U-tube shell-and-tube heat exchanger is investigated by partially replacing conventional metallic …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 685–700 Read article
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Study on Single-Slope Solar Still for Experimental and Data-Driven Analysis for Improving Productivity with Different Basin Materials.
Abstract: This study investigates the single-slope solar still under the diurnal variation of water temperature and distillate yield under identical operating conditions. Experimental analysis was conducted to evaluate the performance enhancement through the incorporation of natural basin materials, namely hemp and sand. The water distillation process is focused on improving potable water productivity and thermal behaviour. The inclusion of hemp and sand in the basin leads to noticeable differences in productivity …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 31–46 Read article
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Photonic Diagnostics: Harnessing Optical Sensing for Non-Invasive Assessment of Coronary Obstruction
Abstract: Cardiovascular diseases (CVDs) remain the leading cause of mortality globally, with coronary artery blockages primarily atherosclerosis representing a critical challenge. The gold standard for diagnosing coronary artery disease remains invasive coronary angiography, a procedure that, while precise, carries inherent patient risks, high costs, and logistical burdens. Optical sensors, leveraging the principles of light-tissue interaction, offer real-time, high-resolution insights into vascular health, paving the way for early detection of arterial stenoses …
Published in International Journal of Optical Innovations & Research · Vol. 4, Issue 1, 2026 · pp. 25–30 Read article
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Evaluation of Mechanical Behaviour of Tungsten Carbide and Magnesium Reinforced Aluminium Matrix Composites
Abstract: With industries like automotive and aerospace also being more inclined on the lightweight material and strength that is much substantial, the aluminium-based metal matrix composite has become a major focus of interest. This paper examines the influence of addition of tungsten carbide (WC) and magnesium (Mg) particles on the mechanical characteristics of Al6063 aluminium alloy. The crucible casting technique was made in two composite compositions 2.5 percent and 5 percent …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 1–8 Read article
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64 Bit ALU DESIGN USING VEDIC MATHEMATHICS
Abstract: High-speed arithmetic operations are crucial for better performance in contemporary digital systems. Particularly for high bit-width operations, conventional arithmetic logic units (ALUs) frequently experience increased latency and complexity. This work presents the design and implementation of a 64-bit Arithmetic Logic Unit (ALU) using notions from Vedic mathematics. The suggested design makes use of a Kogge-Stone Adder for effective addition and the Urdhva Tiryagbhyam sutra for quick multiplication. Among other mathematical …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 4, Issue 1, 2026 Read article
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Fabrication and Comparative Study of Synthetic and Eggshell Waste Derived Hydroxyapatite-Based Composites for Biomedical Applications
Abstract: Hydroxyapatite is widely used as a bioceramic material in orthopedic and dental field because of its exceptional biocompatibility and bioactivity. Hydroxyapatite (HAp) doped with several mineral ions has been frequently reported to further enhance its bioactive nature. Several studies indicate that biological waste materials can serve as calcium sources for hydroxyapatite synthesis, with eggshells being one such promising source. In the present work, two types of hydroxyapatite were synthesized: pure …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 33–46 Read article
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Effect of Red Mud Loading on the Thermal and Mechanical Performance of Polypropylene Composites
Abstract: Waste red mud (RM) serves as a low-cost and sustainable filler material in a polypropylene (PP) matrix. This study investigate the effects of different red mud contents on the dynamic mechanical and thermal properties of polypropylene-red mud (RM-PP) composites where red mud levels range from 0% to 40% (based on weight percentage). Fourier Transform Infrared Spectroscopy (FTIR) was conducted for verifying the presence of both polypropylene and red mud in …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 161–169 Read article
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Signal Drift Compensation in Polymer-Based Wearable Biosensors Using Data Processing Techniques
Abstract: Polymer-based wearable biosensors have emerged as promising platforms for continuous physiological monitoring due to their mechanical flexibility, low operating voltage, and compatibility with soft biological interfaces. However, their long-term deployment remains challenging because of signal drift caused by polymer ageing, hydration–dehydration cycles, ionic trapping, and environmental variations. These effects introduce baseline fluctuations and sensitivity degradation, which compromise the reliability and interpretability of physiological measurements. This study proposes a data-processing–driven framework …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 197–207 Read article
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Tensile and Microstructural Behaviour of Friction Stir Welded AL7050 Hybrid Composites Reinforced with Multani Mitti and Cow Dung Ash
Abstract: The study examines Al7050 aluminum alloy composites made by stir casting and bonded by friction stir welding (FSW), supplemented with environmentally friendly Multani Mitti (MM) and cow dung ash (CDA). The study assesses the effects of different hybrid reinforcement contents (0–8 vol%) on the microstructural properties, hardness, and tensile behavior of the base alloy and its FSW joints. Tensile testing reveals an initial decline at 2% reinforcement but a notable …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 78–89 Read article
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Adaptive Drift Correction in Polymer-Based Wearable Biosensors via Data-Driven Signal Modeling
Abstract: Polymer-based wearable biosensors have emerged as a promising technology for continuous health monitoring due to their mechanical flexibility, biocompatibility, and suitability for long-term physiological interfacing. However, prolonged exposure to biofluids, environmental variability, and mechanical deformation introduces signal drift, which significantly degrades measurement accuracy and limits clinical reliability. This paper presents a data-driven methodology for compensating signal drift in polymer-based wearable biosensors using adaptive signal processing and machine learning techniques. The …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 131–139 Read article
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Image-Based Quantitative Mapping of Structure Property Relationships in Polymer Composite Materials
Abstract: The performance of polymer composite materials is intrinsically governed by their microstructural architecture, which is shaped by manufacturing conditions and constituent interactions. Despite extensive experimental characterization efforts, establishing transparent and quantitative structure–property relationships from microstructural images remains a challenge. In this study, an explainable image-driven framework is developed to systematically correlate microstructural features with composite property indicators. Microstructure images are processed to identify voids, fibers, and filler phases, from which …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 188–196 Read article
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Image-Based Evaluation of Implant Tissue Interface Integrity in Polymer Orthopaedic Devices
Abstract: Polymer orthopedic implants offer radiolucency and mechanical compatibility with bone, but long-term success depends on maintaining a stable implant–tissue interface. Routine imaging is widely available for follow-up, yet interface integrity is commonly judged qualitatively, limiting early detection of fixation compromise and reducing comparability across devices and time points. This work presents an image-based methodology to quantify interface integrity by extracting interpretable interface descriptors from a standardized interface belt around the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 170–179 Read article
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Interfacial Engineering of Carbon Fiber/Epoxy Laminates Using Functionalized Graphene Nanoplatelets: Experimental and Numerical Study
Abstract: Current research work studies the influence of amines(–NH₂) and carboxyl(–COOH) functionalized graphene nanoplatelets on the mechanical and thermomechanical behavior of unidirectional hybrid composite. Composites having different graphene concentration from 0 to 0.7 wt% were fabricated, characterized and analyzed for multiple testing - tensile testing, dynamic mechanical analysis (DMA) and Fourier transform infrared spectroscopy (FTIR). Tensile testing indicates better elastic modulus and tensile strength due to efficient load transfer between nanoparticles …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 61–77 Read article
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Physicochemical Transitions and Polymerization Dynamics in Multi-Generational Dentin Adhesives: A Critical Review of the Resin-Dentin Composite Interface
Abstract: Adhesive dentistry has undergone a transformative refinement over the past three decades, transitioning from technique-sensitive, multi-step etch-and-rinse protocols to streamlined universal formulations. This narrative review critically synthesizes evidence from thirty peer-reviewed investigations to evaluate the evolution of dentin bonding agents from the fourth through the eighth generations. The analysis places particular emphasis on the physicochemical dynamics of the resin-dentin interface, including interfacial bond strength metrics, marginal integrity, and microleakage behavior. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 209–228 Read article
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AI-Integrated Graphene-Modified Polymer Interfaces for Real-Time Crack Detection and Autonomous Healing in Smart Concrete Structures
Abstract: This study presents the design and development of a graphene-reinforced multifunctional polymer composite interface engineered for structural reinforcement, self-sensing, and autonomous healing applications in cementitious systems. A thermosetting polymer matrix embedded with graphene nanoplatelets (0.25–1.5 wt.%) was developed to establish a conductive polymer nano-composite network. Electrical characterization confirmed a distinct percolation threshold at ~0.6–0.8 wt.%, beyond which a sharp increase in conductivity was observed due to the formation of interconnected …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 30–42 Read article
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Structure–Property Modeling of Cement-Based Multi-Component Composites Using Ensemble Machine Learning and Explainable Feature Attribution
Abstract: Accurate prediction of compressive strength is central to structure–property optimization, quality control, and sustainability-driven design in cement-based composite materials. Cementitious systems represent heterogeneous multi-phase composites composed of reactive binder matrices and dispersed aggregate phases, whose macroscopic mechanical performance emerges from complex nonlinear interactions among constituents and curing-dependent microstructural evolution. This study develops a data-driven structure–property modeling framework to quantify the nonlinear dependence of compressive strength on multi-component composite composition and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 112–131 Read article
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Effectiveness of Evidence-Based Pediatric Nursing Practices on Clinical and Developmental Outcomes in Children: A Comprehensive Systematic Review
Abstract: Evidence-based pediatric nursing practices are essential for improving health outcomes among children by integrating clinical expertise with the best available research evidence and patient-centered care approaches. This systematic review examines the effectiveness of evidence-based pediatric nursing interventions on clinical and developmental outcomes in children across various healthcare settings. A comprehensive search of databases including PubMed, CINAHL, Scopus, and the Cochrane Library was conducted for studies published between 2016 and 2026. …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 4, Issue 1, 2026 Read article
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The Green Cost of Generative Ai: Environmental Sustainability Implications of Large-Scale Ai Systems
Abstract: Generative Artificial Intelligence (GenAI) has advanced rapidly in scale and complexity, enabling powerful capabilities in automated content creation, multimodal reasoning and real-time decision support across sectors. While these systems offer significant technological and economic benefits, their environmental implications are not fully examined. Large-scale GenAI models rely on high-performance computing infrastructure that consumes substantial energy and resources throughout their lifecycle, raising critical sustainability concerns. This paper offers a sustainability-oriented assessment of …
Published in International Journal of Sustainability · Vol. 3, Issue 1, 2026 · pp. 12–20 Read article