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1953 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Design and Development of Experimental Test Rig for Fatigue Life Estimation of Freewheel One-Way Clutch Used in Switchgear Applications at High Overrunning Speeds
Abstract: Freewheel one-way clutch (OWC) is a critical component used in industrial circuit breakers/switchgear to facilitate quick disengagement of the drive when an electrical circuit trips under overcurrent. The clutch acts as a safety device to endure high overrunning speeds and allows the drive shaft to rotate at normal operating speeds during each tripping cycle. The trip mechanism utilizes the stored potential energy of the helical compression spring, which is the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 289–299 Read article
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Exploring Sustainable Fuel Production from Waste: A Feasibility Study in Zimbabwe
Abstract: Some organisms are in danger of going extinct, and environmental pollution from waste plastics, tires, and used lubricating oils has significantly contributed to the decline of biodiversity. Tires, plastics, and spent oil all contribute significantly to environmental deterioration, and this issue has been linked to improper treatment and disposal of these materials. Only 15% of the 200 auto technicians surveyed for this study acknowledged that they reuse spent oil, 5% …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 3, Issue 1, 2025 · pp. 30–38 Read article
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Investigating The Mechanical Properties of Sisal/Areca/Sisal Natural Fiber Reinforced Composite Material Treated with NaOH and Filled with Al2O3 and Tio2
Abstract: Biopolymer-based composites which are obtained from the natural resources like plants, animal or mineral based have recently attracted significant interest because they can be used in interesting ways in biology and materials science. These materials are generally non-toxic, reusable, and recyclable, which are useful in many situations where sustainability and environmental protection are important. Plant Based fibers like Bamboo, Coir, Kenaf, Banana, Sisal, hemp and jute are proving their potentiality …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 413–425 Read article
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U-Net Based Approach for Automated Brain Tumor Classification
Abstract: Brain tumor detection and identification play vital roles in diagnostic procedures in the field of medicine, with the conventional analysis of MRI images requiring a lot of time and also subject to variability. The proposed study involves the use of a CNN-U-Net based approach for brain tumor detection and identification automatically. The study uses a database of 3,064 contrast-enhanced T1-weighted MRI images from 233 patients with the tumors of meningioma, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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Evaluating the Role of Platelet Indices, with a Focus on Immature Platelet Fraction (IPF), in Differentiating Hyper-Destructive and Hypo-Productive Thrombocytopenia: A Study from Ludhiana, Punjab, India
Abstract: Background: Thrombocytopenia, characterized by a reduction in platelet count, is commonly observed in clinical settings. Its etiology can be broadly classified into hyper-destructive thrombocytopenia, where platelets are destroyed at an accelerated rate, and hypo-productive thrombocytopenia, where platelet production is impaired. Differentiating between these two causes is essential for effective management. The Immature Platelet Fraction (IPF) has emerged as a promising non-invasive diagnostic tool to distinguish these causes. Objectives: The primary …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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VLSI Based Traffic Light Controller
Abstract: This study details the development and realization of an advanced traffic light control system utilizing VHDL (Very High-Speed Integrated Circuit Hardware Description Language) in conjunction with FPGA (Field Programmable Gate Array) technology. The system is designed to regulate a four-way intersection, with one primary high-traffic road intersecting with a less congested side road. To enhance traffic efficiency and minimize idle times, the model incorporates intelligent features such as a vehicle …
Published in Journal of VLSI Design Tools and Technology · Vol. 15, Issue 2, 2025 · pp. 40–47 Read article
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Biomimicry of Eucalyptus Leaf Design for Optimization and Fabrication of Airfoil
Abstract: Biomimicry is the practice of drawing inspiration from natural forms to solve engineering problems, which has become progressively popular for refining design efficiency and performance. This work discovers how biomimicry can be applied to airfoil design, precisely through the unique structure of Eucalyptus leaves, a concept rarely explored in airfoil profiling. The work presented here, focuses on enhancing airfoil designs by incorporating the intricate features of these leaves. The airfoil …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 359–372 Read article
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Optimization of Turning Process Parameters by Genetic Algorithm Approach
Abstract: In this research, turning parameters were optimized through a genetic algorithm for the purpose to minimize surface roughness and to maximize the material removal rate. High finish quality is guaranteed through minimum surface roughness, and efficient process planning is facilitated through maximum material removal rate optimization. For predicting surface roughness and material removal rate with respect to spindle speed, feed rate, and depth of cut, the empirical models were developed …
Published in Journal of Production Research & Management · Vol. 15, Issue 1, 2025 · pp. 33–41 Read article
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Development of Cost-Effective Nanocarriers for Targeted Drug Delivery in Cancer Therapy in India
Abstract: The growing challenge of cancer in India demands the development of novel treatment approaches that are efficient and less expensive in alleviating disparities related to healthcare access and optimizing outcomes. Among the possible options, the drug delivery systems utilizing nanocarriers have been developed and they provide greater therapeutic targeting, reduced systemic toxicity, and decreased treatment costs over time. In this research, we assess the degrees of awareness, affordability, and acceptability …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 1–7 Read article
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Comparative Evaluation of GPBB and CK-MB in Early Diagnosis of Acute Myocardial Infarction in Diabetic and Non-Diabetic Patients
Abstract: Background: Acute myocardial infarction (AMI) continues to be a leading cause of morbidity and death among people worldwide. To lower the risk of problems, early and precise diagnosis is essential, particularly for diabetes patients. The study investigates the diagnostic value of Glycogen Phosphorylase BB (GPBB), a potential early biomarker of myocardial necrosis, and compares it with CK-MB, a widely used cardiac marker, in AMI diagnosis. Inflammatory markers (hs-CRP, IL-6, TNF-α) …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 33–37 Read article
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Soil Salinity Assessment and Irrigation Water Quality of Humbo Woreda, Wolaita Zone, South Ethiopia
Abstract: Soil salinity affects the majority of Ethiopia's irrigated farmland, and chemical properties of irrigation water quality have major role in assessing the irrigation land salinity. The study has the objective of determining the soil salinity and irrigation water quality. The study was conducted in Humbo Woreda, Wolaita Zone in the South Peoples’ Regional State. The study used standard analytical techniques and methods to analyze different physiochemical parameters of both irrigation …
Published in Journal of Water Resource Engineering and Management · Vol. 12, Issue 2, 2025 · pp. 38–51 Read article
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Doppler Limits of LoRa in LEO: A Critical Review of the First In-Orbit Flight Tests
Abstract: This study provides a comprehensive review of the seminal work by Zadorozhny et al., which presented the first in-orbit flight test results evaluating the impact of Doppler effects on LoRa modulation for Low Earth Orbit (LEO) satellite communications. The review summarizes the original study's methodology using the NORBY CubeSat, details its key findings regarding the operational limits imposed by static and dynamic Doppler shifts across various LoRa configurations (Spreading Factor …
Published in Recent Trends in Electronics Communication Systems · Vol. 12, Issue 2, 2025 · pp. 21–27 Read article
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Lead Ion Removal from Water Using Fava Beans Pod-Derived Phytoadsorbents: A Green Approach
Abstract: The contamination of natural ecosystems—particularly water bodies—with harmful chemical substances poses a serious environmental threat on a global scale. Among these contaminants, toxic heavy metals such as lead, arsenic, cadmium, and mercury are especially concerning due to their non-biodegradable nature and ability to accumulate in living organisms. These metals can enter the human body through the food chain, even at trace levels, leading to various severe health issues, including neurological, …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 3, 2025 · pp. 53–58 Read article
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First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal
Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Crossroads of Ecology and Medicine: Evaluating Pollutant-Induced Risks to Biodiversity and Human Health
Abstract: Environmental pollution has emerged as a central challenge at the crossroads of ecology and human medicine. The rapid pace of industrialization, urbanization, and agricultural intensification has led to an unprecedented release of pollutants into the air, water, and soil—triggering cascading effects on ecosystems and human health. Pollutants such as particulate matter, heavy metals, pesticides, microplastics, endocrine-disrupting chemicals, and persistent organic pollutants not only degrade biodiversity but also exert multifaceted health …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 1, 2025 · pp. 41–53 Read article
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Impacts of Climate Change on Land Degradation: A Review of Mitigation
Abstract: Land degradation has emerged as one of the most pressing environmental challenges globally, significantly impacted by the multifaceted and escalating effects of climate change. The degradation of land, including soil erosion, nutrient depletion, deforestation, and desertification, directly threatens food security, biodiversity, and human livelihoods. As climate change leads to increasingly erratic weather patterns, including prolonged droughts, intense rainfall, and extreme temperatures, land degradation has become more pronounced and widespread, exacerbating …
Published in International Journal of Land · Vol. 2, Issue 1, 2025 · pp. 6–10 Read article
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Effect of Solution Heat Treatment and Aging on the tensile Properties of Ti-6Al-4V Alloy Component Manufactured by Wire Arc Additive Manufacturing
Abstract: Wire Arc Additive Manufacturing (WAAM) is a cost-effective technique for fabricating components from the Ti-6Al-4V alloy, known for its high strength and utility in demanding applications. To maximize its strength, the alloy undergoes Solution Treating and Aging heat treatment, comprising three key steps: (i) Solution Treating: The alloy is heated to 950°C (just below the β transus) and held for 1 hour, increasing the β phase proportion. This step sets …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Fabrication of Natural Fibre Reinforced Polymer Composite by Hand Lay-Up Process
Abstract: The recent development in technologies has increased the usage of non-renewable resources during pro- duction due to remarkable properties. However, it has been a threat and unable to be replenished once used. In addition to this, natural fibre strengthens in a more significant way and it’s widely applicable in polymer composites materials. Furthermore, the use of plant fibres in polymer composites is due to its low cost and significant properties. …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 13–19 Read article
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Geospatial Assessment of Land Use and Land Cover Changes in Debrigarh Wildlife Sanctuary, Odisha: A Twenty-Year Perspective
Abstract: Among the recorded dynamic processes on the surface of the earth is the change in land use and land cover (LULC) pattern as an outcome of several anthropogenic practices. Planning, development, and management of land for sustainable usage of land depend on plotting and tracing the vagaries in LULC. Anthropogenic activity, generally for forestry and food production, is altering the land surface. The steadily diminishing landscape also has tragic implications …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 14, Issue 2, 2025 · pp. 12–27 Read article
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One Nation, One Subscription (ONOS) : Reshaping Library Acquisition in Government Colleges of Gujarat
Abstract: The study investigates the awareness and readiness of library professionals in the government colleges of Gujarat about the One Nation, One Subscription (ONOS) program. The objectives cover to evaluate library professionals’ knowledge, recognize their requirements for infrastructure and training, identify benefits and challenges they predict and recommend the idea for the betterment of the initiative. The study divided responses into five geographical regions of Gujarat like Central, East, North, South, …
Published in Journal of Advancements in Library Sciences · Vol. 12, Issue 2, 2025 Read article