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136 articles for “treatment-resistant”
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Malaria Diagnosis through Conventional Methods: A Comprehensive Review
Abstract: The incidence of drug-resistant parasite strains is rising, there is an apparent increase in the number of cases of malaria worldwide, and in a small number of cases and there has been a dramatic rise in international migration and travel. Over 1 million people die from malaria every year; 90% of these deaths are in African children, who live in tropical and subtropical regions. Although there are now efficient techniques …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 8–14 Read article
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A Review on The effect of Polycystic Ovary Syndrome on some Hormonal and Metabolic Disturbances in Women
Abstract: Polycystic ovary syndrome (PCOS) is a common hormonal condition that affects women of reproductive age. It usually begins to appear during adolescence. The ovaries produce an abnormal amount of "androgens", which are male sex hormones that are usually found in women in small quantities. Ovarian syndrome causes hormonal imbalances, irregular menstrual cycles, increased cysts in the ovaries, in addition to hair growth all over the body, acne, and pain in …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 21–28 Read article
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Advances in Polymer-Based Materials for Dental Applications: A Case Study on PVC and Ceramic Coatings in Digital Mouth Mirrors
Abstract: Polymeric materials play a crucial role in modern dentistry, providing improved mechanical properties, biocompatibility, and enhanced functionality in dental instruments. These materials contribute significantly to the advancement of dental tools, ensuring durability, safety, and efficiency. This study explores the application of polyvinyl chloride (PVC), ceramic coatings, and anti-fog polymer layers in the development of a digital mouth mirror. The integration of these materials results in enhanced durability, corrosion resistance, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 244–252 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Multitarget Molecular Docking Using Curcuma longa Phytocompounds for Polycystic Ovary Syndrome Treatment
Abstract: Objective: The primary goal of this research is to understand and describe specific aspects of molecular interaction, it includes studying various aspects such as binding affinity, binding mode, and stability of the ligand-protein complex. Molecular docking is a computational technique used to predict the preferred orientation of one molecule to a second when bound together to form a stable complex. In this study, molecular docking will be employed to stimulate …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 15–28 Read article
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Comparative Analysis of Natural and Synthetic Fibre-Reinforced Composites: Mechanical Properties, Processing, and Sustainability Considerations
Abstract: The development of fibre-reinforced composites has significantly advanced engineering applications due to their excellent strength-to-weight ratio, corrosion resistance, and versatility. Synthetic fibres such as glass and carbon provide superior mechanical performance, but their production is energy-intensive and environmentally harmful. Natural fibres, including jute, flax, banana, and hemp, offer biodegradability, lower cost, and sustainability benefits, though they often fall short in strength and durability. Hybrid composites frequently demonstrate improved performance by …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 3, 2025 · pp. 77–95 Read article
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Innovative Technology for Water Purification
Abstract: Water purification is critical for ensuring access to clean and safe drinking water, which is essential for public health, environmental sustainability, and economic development. Recent advancements in water purification technologies offer innovative solutions to address the growing challenges of water contamination and scarcity. This paper explores state-of-the-art technologies that are revolutionizing the field of water purification. Key innovations include nanotechnology-based filtration systems, advanced oxidation processes (AOPs), biomimetic membranes, and solar-powered …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 2, 2024 · pp. 11–16 Read article
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Application of Medicinal Plants to Cure Mental Disorders
Abstract: Mental fitness is a state of well-being in which individuals apprehend their talents, manage existing pressures, remain efficient, and contribute to their groups. Mental contamination regularly used interchangeably with intellectual illness, is vital to apprehending and addressing man or woman desires and challenges. Schizophrenia, a psychological disorder characterized by hallucinations and delusions, is a complex situation with two important classes: bad symptoms (withdrawal from social interactions, loss of force, and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 69–78 Read article
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Performance Enhancement of COC-Modified LLDPE Films: Optimization of Stiffness, Tear Resistance, and Barrier through Plasma Surface Modification
Abstract: This study explores the development of high-performance packaging materials by blending commodity Linear Low-Density Polyethylene (LLDPE) with engineering cyclic olefin copolymer (COC) as a performance modifier. To leverage the processability of LLDPE alongside the structural rigidity of COC, blends were prepared at various weight ratios (95/05, 90/10, 85/15, and 80/20) using twin-screw melt extrusion, followed by the production of films and sheets via blown film extrusion and compression molding. The …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 128–143 Read article
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Sustainable Cotton Crop Productivity through Precision Weed Detection: A Deep Learning-Based Approach with UAV Integration
Abstract: Weeds present a major challenge to crop productivity by competing with crops for vital resources, including water, sunlight, and nutrients, often resulting in significant yield reductions. On a global scale, weeds are responsible for approximately 13.2% of annual crop losses, a quantity sufficient to feed nearly one billion people. These invasive plants disrupt agricultural systems and adversely impact crop yields. Given their uneven distribution in fields, ground or aerial robots …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 19–26 Read article
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Review on Formulation and Evaluation of Herbal Gel of Moringa oleifera and Aloe vera for management of acne
Abstract: Acne vulgaris is a prevalent chronic inflammatory disorder of the pilosebaceous units, characterized by excessive sebum production, follicular hyperkeratinization, bacterial colonization, and inflammation. Conventional therapies often result in side effects and the development of drug resistance, prompting the exploration of natural alternatives. This review highlights the potential of Moringa oleifera and Aloe vera in acne management via topical drug delivery systems (TDDS). Moringa oleifera is rich in bioactive compounds such …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 10–16 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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Synthesis of Zinc Oxide Nanoparticles Through Polymeric Precursor Route and their Integration into Functional Nanocomposites
Abstract: A polymer precursor approach for creating zinc oxide (ZnO) nanoparticles with regulated size and shape is described in this work. By stabilising and capping particles, the polymer-assisted pathway efficiently reduces particle agglomeration while facilitating controlled nucleation and growth. The surface shape and dispersion of the produced ZnO nanoparticles were assessed using the scanning electron microscopy (SEM). When compared to traditional synthesis techniques, the addition of polymer greatly enhanced surface homogeneity …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 883–890 Read article
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Synthesis of A Supercapacitor Based on Nanomaterials
Abstract: Demand for various energy storage technologies in electronic and electrical devices continuously goes on increasing. In that context, objective of this research work is to develop and test an electrode of a energy storage module (supercapacitor) using nickel hydroxide and carbon-based nanocomposite materials. Electrochemical performance of electrode is enhanced by optimizing synthesis parameters and designing the electrochemical cell. Conventional and all solid-state supercapacitors are developed with notable electrochemical performance. Pure …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 4, Issue 1, 2026 · pp. 24–39 Read article
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Assessment of exacerbation of Depression in pulmonary tuberculosis patients by using PHQ-9 scale at Tertiary Care Hospital
Abstract: Context: Depression leads to more dysfunction and stress, which could affect the patient's life condition. Tuberculosis is a leading cause of comorbidity with depression. Those suffering from tuberculosis and depression are at higher risk of bad health-seeking nature, resulting in higher morbidities, drug resistance, and mortality. The relationship is not well established. Aims: To identify multiple variables/ dependent factors affecting depression respectively in tuberculosis patients and check the medication adherence …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 24–31 Read article
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Melanoma Skin Cancer Detection Using Deep Learning
Abstract: Cancer as one of the major diseases rank in the World is still very challenging to diagnose and treat hence need for the technological advancements. Chemotherapy, radiation, as well as surgery therapies have several drawbacks including non-selective action, damage to healthy tissues, and multi-drug resistance. Smart nano-theranostics, an advanced integration of nanotechnology with diagnostic and therapeutic modalities, offers a next-generation approach for precision oncology. Thus, the development of multifunctional nanoparticles …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article