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562 articles for “therapy”
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Machine Learning in Nuclear Medical Applications: A Review of Research Frontiers
Abstract: Nuclear medicine, encompassing PET, SPECT, and targeted radionuclide therapy, generates high-dimensional, quantitative data uniquely suited for machine learning (ML) analysis. This review synthesizes current research applications of ML across six key domains. Positron emission tomography (PET), single-photon emission computed tomography (SPECT), and targeted radionuclide therapy are examples of nuclear medicine modalities that generate high- dimensional, quantitative datasets that are particularly well-suited for machine learning (ML)-driven analysis. These imaging methods provide …
Published in Journal of Nuclear Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 19–24 Read article
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Concept and Management of Haemorrhoids (Bawaseer) in Unani System of Medicine
Abstract: Haemorrhoids are one of the most prevalent diseases with significant impact on quality of life. Haemorrhoids commonly known as piles are defined as swollen, inflammed veins around the anus or the lower part of rectum. The most common symptom of haemorrhoids is rectal bleeding and discomfort before or after bowel movements. According to the Unani Physicians, the most common cause of the haemorrhoids is the accumulation of the abnormal melancholic …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy Read article
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A Review Article on Clinical Pharmacy Overview
Abstract: Clinical pharmacy is the branch of pharmacy and is the practice that helps the pharmacist provide services to promote rational and economical drug therapy that it’s appropriate, safe and cost effective which successively optimizes the utilization of medication and promote wellness, health and disease prevention. The reason for emergency of clinical pharmacy practice has been remarkably consistent worldwide. Clinical pharmacist provide care for patients altogether health care setting, clinical pharmacist …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 2, 2023 · pp. 06–12 Read article
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An AAV Vector for Inducible Gene Expression Preferentially in Muscles
Abstract: Adeno associated viral (AAV) vectors has been used widely in gene therapy and efforts have been made to improve their utility by adding genetic elements that would enable targeting transgene expression to particular cells or tissues of interest and permitting on/off regulation of expression. In this study, we designed a recombinant AAV9 variant PHP.eB vector with muscle creatine kinase (Mck)-derived enhancers, a synthetic muscle-expression promoter, in combination with a third-generation …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 46–61 Read article
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Navigating the Depths of Cancer Stem Cells: Unraveling Resistance Mechanisms and Emerging Therapeutic Strategies
Abstract: In the past few decades, comprehensive evidence has convincingly established the presence of cancer stem cells (CSCs) as a minor subset within tumors, contributing to an unusually elevated level of cellular diversity within the malignancy. CSCs are functionally identified by their capacity for self-renewal and differentiation, frequently influenced by signals from their surrounding microenvironment. The interconnected transcriptional, post-transcriptional, metabolic, and epigenetic regulatory networks govern the biological characteristics of CSCs. CSCs …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
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Management of Thermal Burns over Breast – Our Experience
Abstract: The intricate challenge of restoring normal anatomy with minimal deformity in burns over the breast region has prompted the development of innovative tissue regeneration approaches. Addressing the complex nature of challenging wound patterns necessitates a multidisciplinary team with diverse expertise. In our concerted effort, we have successfully integrated advanced reconstructive techniques with regenerative medicine modalities to enhance outcomes in the intricate realm of complex breast reconstruction post-thermal burns. Our approach …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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The Effects of HIV/AIDS Worldwide
Abstract: The Human Immunodeficiency Virus (HIV), which targets immune system conductors (CD4 cells), has infected millions throughout the world. HIV lowers the body's defences by infecting certain bodily fluids (blood, sperm, vaginal fluids, and breast milk) through unprotected sex, contaminated needles, or mother-to-child transmission. Early flu-like symptoms may go unrecognised, but if not treated, HIV advances to AIDS, which is characterised by severe immune system impairment. However, advances in antiretroviral therapy …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 26–31 Read article
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Development of Formulation for Dry Powder Inhalation of Amino Acids Aimed at Smoking Cessation: A Biomedical Perspective
Abstract: This study aims to develop an effective and compliant therapy targeting the lungs through the strategic utilization of amino acids, which play a crucial role in modulating mood and behavior during activities like smoking. L-Tryptophan and L-Tyrosine were finely micronized within the 2–4 µm range, with lactose serving as a carrier, to create a dry powder inhalation formulation. The combination of these amino acids is anticipated to elicit a synergistic …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 18–36 Read article
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Role of Functional Regenerative Trilaminar Scaffold Dressing in Wound Bed Preparation
Abstract: Advancements in wound healing have incorporated tissue regeneration therapy as a crucial tool for managing both acute and chronic wounds. Bio constructs designed to facilitate wound regeneration utilize natural, artificial, or hybrid materials, collectively referred to as regeneration scaffolds. The components of regeneration scaffolds play a crucial role in enhancing the skin's natural self-renewal abilities and accelerating the healing process. These scaffolds are designed to provide essential growth factors and …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 70–75 Read article
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Progeria Syndrome Unveiled: A Scientific Odyssey into Premature Aging Mechanisms and Therapeutic Frontiers
Abstract: Progeria, or Hutchinson-Gilford Progeria Syndrome (HGPS), is a rare and fatal genetic disorder in childhood, exhibiting features akin to premature aging. Despite normal appearances in infancy, affected children face accelerated aging with distinct facial characteristics, including micrognathia, dental malformations, lower body weight, early hair loss, decreased joint mobility, lipodystrophy, etc. The cause of HGPS is a point mutation that occurs at the exon 11 of the LMNA gene which normally …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 52–68 Read article
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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Strengthening Neurological and Familial Interventions: Adult Coping Following Pediatric Brain Injury and Comorbidity
Abstract: Background: Pediatric traumatic brain injury (PTBI) contributes to long-term physical, cognitive, and emotional difficulties and is a major cause of mortality and disability in children. An estimated 200,000 fatalities in India each year are attributed to traumatic brain injuries, with PTBI accounting for a significant share of these cases. Accidents, abuse, and sports injuries are just a few of the causes of post-traumatic brain injury (PTBI), which can result in …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 7–15 Read article
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Effectiveness of Spencer Technique of Mobilization on Adhesive Capsulitis: A Single Case Study
Abstract: Background: Frozen shoulder, or adhesive capsulitis, is a condition characterized by pain, restricted motion, and stiffness in the shoulder joint. This occurs due to inflammation and the thickening of the joint capsule. The Spencer technique, is a manual therapy method consisting of seven steps designed to improve shoulder function by enhancing joint mobility, circulation, and lymphatic flow. These movements target shoulder extension, flexion, circumduction, abduction, and adduction, to reduce stiffness …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 14–20 Read article
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Antibiotics in the Modern Era: Challenges, Misuse, and the Fight Against Resistance
Abstract: Overuse and inappropriate use of antibiotics in human medicine, agriculture, and environmental pollution. It is one of the biggest public health risks of the 21st century. The discovery of new antibiotics slowdown and the emergence of multidrug-resistant (MDR) microorganisms has highlighted the urgent need to Creative approaches to fighting opposition. This review explores the current challenges in antibiotic use, the factors driving resistance, and the strategies being implemented to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 57–70 Read article
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Computational Approaches to Understanding Cellular Signaling Pathways
Abstract: Cellular signaling pathways are fundamental in regulating vital processes, such as cell growth, differentiation, and apoptosis. The intricate and interconnected nature of these signaling networks requires sophisticated methods for their analysis. Computational approaches, including mathematical modeling, network analysis, and machine learning, have revolutionized the way researchers analyze and simulate cellular signaling. This article provides a comprehensive overview of computational strategies employed to model signaling pathways, with a focus on integrating …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 8–13 Read article
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Impact of in-Home PT on Mobility and Independence in Geriatric Patients with OA
Abstract: Osteoarthritis (OA) is a leading source of pain and functional challenges in older adults, significantly impacting their mobility and independence. In-home physical therapy (PT) offers a personalized, patient-focused approach to managing OA in a comfortable setting, providing targeted treatments tailored to the specific needs of elderly patients. This study explores how in-home PT can enhance joint function, alleviate pain, and boost the overall quality of life for older adults living …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 65–72 Read article
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Phytomedicine in 21st century: challenges, innovations & future directions
Abstract: Phytomedicine, the use of plant-derived substances for therapeutic purposes, has experienced significant advancements and challenges in the 21st century. This review explores the current state of phytomedicine, highlighting its advantages, such as natural ingredients, fewer side effects, and cultural acceptance, as well as its disadvantages, including variable quality, lack of standardization, and limited research. The challenges faced by phytomedicine are discussed, focusing on issues of standardization, regulatory discrepancies, scientific evidence …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 86–95 Read article
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Revolutionizing Anti-Allergy Medications: A Comprehensive Review of Target Discovery and Medicinal Chemistry
Abstract: Above the past few decades, the prevalence of allergy illnesses has been steadily rising, impacting 20–30% of the world's population. Multiple targets are involved in allergic reactions to infections of the skin, digestive tract, and respiratory system. Developing medications with a good curative efficacy and minimal side effects while utilizing novel multi-targets and processes in accordance with the clinical features of various allergic populations and allergens is the primary challenge …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 49–54 Read article
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The Effective Unani Management of Bell’s Palsy: A Case Study
Abstract: Bell’s palsy (Laqwa) is an acute, idiopathic, unilateral LMN-type facial nerve palsy characterized by a rapid onset of weakness of facial muscles on the affected side, drooping of eyelids on the same side, difficulty in closing the eye completely, drooping of the angle of the mouth on the same side, saliva dribbling from the affected side and mouth deviating towards the healthy side. It causes facial dysfunction and alters the …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 1, 2025 · pp. 33–37 Read article
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Alternative Medicine: A Review Article the Lupus Journey from the Diagnosis to Recovery and Beyond
Abstract: Lupus, a chronic autoimmune disease, presents a complex and often volatile journey for patients, from diagnosis to recovery and beyond. The course is usually characterized by periods of acute flare-ups, followed by remissions, with different symptoms affecting different organ systems. This review delves into managing lupus with alternative medicine, highlighting how it can work alongside conventional treatments. It covers topics like diet, herbal remedies, acupuncture, and mind-body practices, all aimed …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 9–18 Read article