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646 articles for “T cells”
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Design and Analysis of Fluid Pressure in Microchannel for Healthcare Application
Abstract: The research article study explores an innovative approach for optimizing fluid pressure within microchannels using 2D integrated microcantilevers. These microcantilevers, strategically placed within the microchannel, serve as sensitive sensors to monitor fluid pressure variations. The computational simulations illustrate the effective approach to achieving improved pressure measurement for cell separation outcomes. The integrated microcantilever can determine the fluid pressure inside the microchannel, and also determine the pressure required for the cell …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 553–565 Read article
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Immune Dysregulation and Cytokine Circuitry in Genital Endometriosis: Mechanistic Insights and Next-Generation Immunotherapeutic Strategies
Abstract: Genital endometriosis is increasingly recognized as an immune-mediated inflammatory disorder driven by complex interactions between dysregulated immune cells, cytokine hubs, and microbiome-derived modulators. This review introduces a novel “immune–cytokine circuitry” framework that unifies innate and adaptive immune abnormalities with key cytokine loops sustaining chronic inflammation, angiogenesis, neuroinflammation, and immune tolerance. Within this circuitry, macrophage polarization, dendritic cell immaturity, NK-cell anergy, Treg expansion, Th17 amplification, and B-cell–mediated autoimmunity converge to establish …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 06–16 Read article
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Human Resource Cell Support for Employees Mental Health and Well Being
Abstract: This study explores the persistent issue of mental health in the workplace and evaluates how collaboration among human resource (HR) teams can improve the day-to-day experiences of employees living with mental health conditions. To capture an accurate and timely understanding of effective organizational responses, the research employs a mixed-methods approach to examine the strategies required to address the ongoing mental health challenge. Additionally, this study aims to close the gap …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 3, 2025 Read article
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Smart Drug Delivery Using Nanorobots
Abstract: In recent years, the field of micro/nanorobot research has gained popularity. Because it can be used in targeted medication distribution, surgical procedures, disease detection, etc., it has enormous promise in medical therapy. Different from conventional medication delivery, which depends on blood flow to drug delivery to difficult-to-reach locations is made possible by the planned micro/nanorobots' ability to move independently. Micro/nanorobots were powered by either endogenous power (chemical reaction energy) or …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Enhancing Power Conversion Efficiency in Tandem Solar Cells with Temporal Dynamic Graph Neural Network
Abstract: In modern homes, people want good comfort and also less electricity bill, so managing heating load and cooling load become very important. Heating Load (HL) and Cooling Load (CL) depend on many things like wall material, window size, sunlight, ventilation, and weather. Because of this many factors, calculation and optimization of HL and CL is little difficult and many time normal formulas give wrong or not perfect results. So in …
Published in Journal of Semiconductor Devices and Circuits · Vol. 13, Issue 2, 2026 Read article
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Charging System for Electric Vehicle and Hybrid Electric Vehicle in Running Condition: A Review
Abstract: This study examines comparative studies of three different charging systems used in electric vehicles while they are moving or operating. It also deals with the idea of using an alternator at each wheel of the vehicle to charge the non-connected set of batteries, as well as a brief explanation of the principles, mechanisms, design, and constraints of fuel cells, solar panels, and regenerative brakes. These are some of the most …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 2, 2024 · pp. 10–18 Read article
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Electrospun Antibacterial Polymer Composite Scaffolds Incorporating Silver Nanoparticles for Enhanced Wound Healing
Abstract: The present study focuses on the synthesis and characterization of electrospun polycaprolactone (PCL)/chitosan nanofiber scaffolds incorporated with silver nanoparticles (AgNPs) to enhance antibacterial activity and biological performance. Uniform nanofibers with controlled morphology were fabricated using electrospinning, and different AgNP concentrations were introduced to investigate their influence on fiber structure, antimicrobial response, and cellular interactions. Scanning electron microscopy (SEM) revealed that increasing AgNP content resulted in well-distributed fibers with reduced diameters, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1025–1051 Read article
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Section Cutting in Histopathology: An Update
Abstract: Histopathology is the microscopic examination of tissues to diagnose and study diseases, more significantly the diagnosis of cancer. It plays a pivotal role in modern medicine, serving as the gold standard for definitive diagnosis in a wide range of conditions. Through meticulous analysis of tissue morphology (structure) and cellular characteristics, histopathology provides crucial information for disease classification, staging, and guiding patient management. In the world of histopathology, where microscopic details …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 29–34 Read article
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Delay Analysis of HS-14T 45nm CMOS SRAM with Different SRAM Techniques for Improvement in Speed
Abstract: This paper presents a novel HS-14T design aimed at significantly improving read and write delays compared to conventional 6T and other memory cells RHRD-12T, SEUH-12T, and NHRC-14T. As technology scales, the demand for faster and more stable memory cells becomes increasingly critical. Our proposed HS-14T incorporates additional transistors to enhance stability and reduce access times, resulting in notable performance gains. Comprehensive simulations reveal that the HS-14T SRAM cell substantially reduces …
Published in Journal of VLSI Design Tools and Technology · Vol. 14, Issue 2, 2024 · pp. 1–13 Read article
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Metabolites in Modern Medicine: Decoding the Future of Health and Diseases
Abstract: The end products of many metabolic processes in cells are called metabolites. Each reaction contributes a specific metabolite. Metabolites act as fingerprints of on-going biological processes. Constant changes in cellular composition due to both environmental and internal factors. By analysing the types and presence of metabolites, scientists can effectively reconstruct the inner workings of a cell or organism. In the past, analysing metabolites was a slow and tedious process, often …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 1–13 Read article
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Iota carrageenan, a Sustainable polymer transformed into a nanogel formulation, by using environment friendly method for antitumor action
Abstract: In the pharmaceutical field, the utilization of polymers, both in their natural form and through chemical modifications, holds immense importance. In this context, a novel and eco-friendly method for the synthesis of nano carrageenan-based polymers has been developed. The efficacy of carrageenan in this domain is attributed to its crosslinking and biological properties, which are largely influenced by its sulfate ion content. This study aims to formulate nanogels via a …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 881–889 Read article
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Repurposing Approved Immunomodulatory Drugs for Target Proteins in the Pancreas of European eel: A Molecular Docking Approach
Abstract: Leishmaniasis is a disease caused by tiny parasites called Leishmania, which spread to humans through the bite of an infected female sand fly. The disease manifests in three different forms, and the protein calcitonin promotes the disease’s spread. By reducing blood calcium levels, inhibiting osteoclast activity, increasing calcium excretion, and possibly playing a role in neurotransmitter modulation, calcitonin, a hormone released by vertebrates, promotes the progression of pathogenesis and lessens …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 12–19 Read article
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Light-Dark Cycle Disruption in Hypothalamus Tissue of Mus Musculus Causes Change in the Expression of Gm45928 Gene
Abstract: The majority of organisms on earth display consistent 24-hour rhythms in their physiology and behavior due to circadian biology. Light and dark cycles play a key role in setting our internal body clock, which controls things like our sleep patterns, hormone levels, body temperature, and metabolism. The disruption of the light-dark cycle has significant effects on the molecular and behavioral rhythms of the circadian clock of hypothalamus. Gm45928 is a …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 32–46 Read article
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Clone-Specific Drug Delivery Systems: Targeted Approaches and Future Clinical Applications
Abstract: Clone-specific drug delivery systems represent a transformative frontier in personalized medicine, addressing the longstanding challenge of clonal heterogeneity within diseases such as cancer, infectious diseases, and autoimmune disorders. Traditional drug delivery platforms often fail to discriminate between pathogenic and healthy cells, leading to systemic toxicity and reduced therapeutic efficacy. In contrast, clone-specific systems aim to selectively target and eliminate disease-driving cellular clones based on unique molecular signatures, thereby improving treatment …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 21–29 Read article
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Pharmaceutical Excipient from Agriculture Waste Product
Abstract: Agriculture produces a large Amount of waste, which contain a high amount of cellulose line polysaccharide that form a large part of the plant solid cell wall. This waste product can be use efficiently by a variety of recycling method such as energy source, source of large compound such as cellulose, gum polymers etc. disposal of waste from fruit bearing industry has been problem due to the high cost travel …
Published in Research and Reviews: A Journal of Toxicology Read article
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Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management
Abstract: Insulin's pivotal function lies in meticulously regulating blood sugar levels, thus guaranteeing cells access to the necessary energy for optimal functionality. When there is a rise in blood sugar, after a meal, the releases insulin gets released from the pancreas to facilitate the uptake of glucose by cells. Insulin primarily acts on muscle, fat, and liver cells, promoting the uptake of glucose from the blood. Another way to store glucose …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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Design of Integrated DC/DC Converter Topology for Hybrid Vehicle
Abstract: Hybrid vehicles traditionally rely on separate DC/DC converters for both the battery and fuel cell, which often leads to increased size, higher costs, energy losses, and limited performance. This paper presents an improved solution: a compact, integrated DC/DC converter with a non-isolated, multi-port design. This new approach simplifies the system by combining the fuel cell and battery into a single, unified converter, reducing the typical drawbacks of conventional designs. The …
Published in Journal of Instrumentation Technology & Innovations · Vol. 15, Issue 1, 2025 · pp. 25–31 Read article
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Resource Reservation Approach: Application in Wireless Network
Abstract: This paper presents an enhanced resource reservation and call admission control strategy tailored for cellular networks. The proposed method uses user mobility trends to improve the efficiency of resource usage while avoiding significant network congestion. The call admission control mechanism is activated each time a new or handoff service request occurs, ensuring that resources are allocated efficiently to uphold a steady quality of service (QoS) for multimedia traffic. This mechanism …
Published in International Journal of Wireless Security and Networks · Vol. 3, Issue 1, 2025 · pp. 9–12 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article