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220 articles for “disease risk”
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Blood Cell Saver Machine
Abstract: Intraoperative Cell Salvage (ICS) is a crucial technique in modern surgical practice aimed at minimizing the need for allogeneic blood transfusions. By collecting, filtering, washing, and re-infusing a patient’s own blood lost during surgery, ICS provides a safer and cost-effective alternative to donor transfusion, reducing the risk of transfusion-related infections and immunologic reactions. Initially conceptualized in the early 19th century, ICS technology evolved significantly with the introduction of the Cell …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 51–59 Read article
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SiRNA-Based Multivalent Vaccines: A Systematic Review of Potential Risks, Benefits, and Future Applications
Abstract: Background: Small interfering RNA (SiRNA) technology represents a promising innovation in vaccine development, especially for multivalent vaccines that can target multiple pathogens or antigenic variants simultaneously. siRNA-based vaccines offer a unique mechanism to induce specific immune responses, presenting an adaptable and potentially powerful tool for tackling infectious diseases and cancer. Methods: This systematic review synthesizes recent studies on siRNA multivalent vaccines, focusing on their immunogenicity, safety, and effectiveness. We reviewed …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 43–49 Read article
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Climate Change Impacts on Health: Addressing Temperature Variations With Homeopathic Solutions
Abstract: This study is focussed on the impacts of climate change on health, specifically focusing on temperature variations and proposing homeopathic solutions. Climate change, recognized as a critical issue of the 21st century, has wide-ranging effects on human health, including direct impacts such as heat-related illnesses and deaths, as well as indirect effects like increased prevalence of vector-borne diseases and food shortages. Vulnerable groups, including the elderly, are especially at risk. …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
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Mid-Year Epidemiological Profile of COVID-19 Posi ve Cases in Rajasthan, India
Abstract: Background: COVID-19, caused by SARS-CoV-2, has posed persistent public health challenges globally since its emergence in late 2019. India, through enhanced surveillance and vaccina on, has seen a progressive decline in case burden. Despite improvements, localized surges and emerging variants necessitate con nuous monitoring. Rajasthan, with its urban-rural health dispari es, experienced a modest resurgence of cases in early 2025, raising concerns about exis ng immunity gaps and health system …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Breaking the Cycle: The Impact of Hygiene Deficiencies on the Health of the Poor
Abstract: Poor sanitation and hygiene present significant health risks, particularly for individuals in low- income communities. Inadequate sanitation systems increase the likelihood of exposure to harmful microorganisms found in contaminated water, food, and environments. This exposure contributes to the spread of waterborne diseases such as cholera, dysentery, and typhoid, along with various gastrointestinal illnesses. Limited access to clean water and soap for handwashing exacerbates these risks, particularly for children, who are …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 22–39 Read article
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A Research Study on Cognitive Health Benefits of Nicotine to the Human Body
Abstract: Background: Nicotine has been primarily known for its addictive properties and associated health risks, particularly in tobacco products. However, recent research has highlighted nicotine’s potential cognitive health benefits, especially in neurodegenerative diseases like Alzheimer’s and Parkinson’s. This study investigates smoking prevalence across mental health conditions, and cognitive impairments in various psychiatric disorders, and explores the possible cognitive health benefits of nicotine. Methods: Data on age and gender distribution, smoking prevalence, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 1, 2025 · pp. 16–23 Read article
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The Effects of Steroids on One’s Health
Abstract: The widespread use of steroids for both medicinal and non-medical purposes is a significant issue in contemporary culture. This article examines the considerable impact of steroids on human health, focusing on the therapeutic benefits and the adverse side effects associated with their consumption. In the treatment of conditions, such as inflammation, autoimmune disorders, and hormone imbalances, steroids, are frequently prescribed, providing significant relief from symptoms. However, the abuse of these …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 47–63 Read article
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Calf Mortality in the Tropics: Multidimensional Challenges and Implications for Sustainable Dairy Development
Abstract: Calf mortality remains a significant challenge in tropical dairy farming, posing threats to productivity and sustainability. This review explores the multifactorial factors contributing to calf mortality in the tropics, including environmental stress, infectious diseases, nutritional deficiencies, management practices, genetic factors, and social dynamics. Tropical climates, characterized by extreme temperature variations, humidity, and poor shelter, exacerbate stress and compromise calf health. Infectious diseases, such as bacterial, viral, and parasitic infections, coupled …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 3, 2025 · pp. 7–23 Read article
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Microneedles: An Innovative Drug Delivery System
Abstract: Microneedles represent a groundbreaking innovation in drug delivery systems, offering a transformative alternative to conventional hypodermic needles and transdermal patches. This advanced technology combines the precision and efficacy of needle-based delivery with the convenience and pain-free nature of patches, creating a minimally invasive platform that addresses many limitations of traditional drug administration. Microneedles are designed to penetrate the stratum corneum – the skin’s outermost layer – without reaching pain-sensitive nerves …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 60–67 Read article
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Photonic Diagnostics: Harnessing Optical Sensing for Non-Invasive Assessment of Coronary Obstruction
Abstract: Cardiovascular diseases (CVDs) remain the leading cause of mortality globally, with coronary artery blockages primarily atherosclerosis representing a critical challenge. The gold standard for diagnosing coronary artery disease remains invasive coronary angiography, a procedure that, while precise, carries inherent patient risks, high costs, and logistical burdens. Optical sensors, leveraging the principles of light-tissue interaction, offer real-time, high-resolution insights into vascular health, paving the way for early detection of arterial stenoses …
Published in International Journal of Optical Innovations & Research · Vol. 4, Issue 1, 2026 · pp. 25–30 Read article
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Infectious illnesses in areas of violence and among refugees
Abstract: Infectious illnesses are a huge and ongoing hazard in conflict zones and among refugee populations. This is because frail health systems, population relocation, and poor living conditions all come together to make transmission risks higher. Armed conflict undermines vital public health infrastructure, such as vaccination programs, disease surveillance, water and sanitation systems, and access to medical care, resulting in the resurgence and proliferation of avoidable and treatable illnesses. Refugee camps …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 36–40 Read article
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The Interplay Between Hyperglycemia, Endothelial Dysfunction, and Cardiovascular Risk in the Context of COVID-19: Implications for Long-term Health
Abstract: The COVID-19 pandemic has highlighted the potential impact of hyperglycemia, especially its link to cardiovascular disease (CVD) and endothelial dysfunction. COVID-19 can cause systemic inflammation and endothelial damage, worsening complications related to hyperglycemia. Persistent inflammation and endothelial dysfunction are crucial elements in the progression of atherosclerosis and other cardiovascular diseases. The long-term health effects of COVID-19, known as “Long COVID” or post-acute sequelae of SARS-CoV-2 infection (PASC), have raised concerns …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 27–31 Read article
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Horizon Scanning and Early Assessment of Health Technologies for the Treatment of Orphan Diseases
Abstract: The theoretical foundations and regulatory framework of the processes of the formation of an effective health technology assessment (HTA) system at the early stages of the life cycle of medicines are analyzed in the article. Particular attention is paid to horizon scanning (HS) and early assessment of expensive innovative drugs utilized for treating rare diseases. In order to inform policymakers, purchasers, and providers (to prioritize MT research, financial, and operational …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 32–39 Read article
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An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia
Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article
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Studying the effects of Exposure to Chemicals on The brain and Nervous System and The risk of Chemical Pollution
Abstract: Scientific research and studies on chemical pollution show that exposure of the brain and nervous system to chemicals causes serious damage ranging from cognitive, motor, and nerve cell disorders to chronic diseases such as Alzheimer's and neurological paralysis. These substances (such as lead ions, mercury, solvents that combine and dissolve easily in the blood, and pesticides) disrupt neurotransmitters and cause cell damage, especially during the early stages of body development. …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 Read article
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Synthesis and Evaluation of New Coumarin Derivatives for Inflammatory Bowel Disease Against DSS-Induced Acute Ulcerative Colitis Mice Model
Abstract: Objective: The discovery of the now numerous mouse models of intestinal inflammation has increased our understanding of the intestinal inflammation that occurs in inflammatory bowel disorders (IBD). This study aimed to investigate the use of a standardized animal model subjected to coumarin derivative treatment, and the action of synthesized molecule administration of dextran sodium sulphate (DSS)- induced colitis in experimental mice. Materials and Methods: We generated a variety of unique …
Published in Journal of Modern Chemistry & Chemical Technology Read article
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Role of Ginger (Zingiber officinale Roscoe) in Sustainable Health
Abstract: Attaining sustainable health involves a comprehensive blend of multiple factors, including structural, physiological, metabolic, and psychological aspects, alongside the cultivation of self-awareness and a sense of fulfillment. The World Health Organization (WHO) underscores in its 2030 Agenda for Sustainable Development that lifestyle-related illnesses, especially non-communicable diseases (NCDs), present considerable hurdles to sustainable progress, stressing the importance of mitigating their risk factors. Nutrition is acknowledged as a cornerstone of health preservation, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 72–76 Read article
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Driving Determinants Influencing Mortality of Goats in the Tropics: Challenges for Sustainable Livestock Development
Abstract: Goat mortality in the tropics is driven by multifactorial determinants that pose critical challenges to sustainable livestock development. Key contributors include infectious diseases, such as peste des petits ruminants, goat pox, enterotoxemia, and haemonchosis, which remain prevalent due to limited vaccination coverage and inadequate biosecurity measures. Bacterial infections, like pneumonia and caseous lymphadenitis, along with parasitic infestations, such as coccidiosis and liver fluke, significantly reduce goat survival rates, especially in …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 2, 2025 · pp. 29–48 Read article
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Vaccination in the Era of Precision Medicine: Tailoring Immunization Strategies for Individual Risk Profiles
Abstract: The introduction of precision medicine has caused a paradigm change in the vaccine landscape. Conventionally, vaccination programmes have been homogeneous, targeting immunity at the population level without taking into consideration the individual differences in immune response and vulnerability to diseases that can be prevented by vaccination. However, a more individualised approach to immunisation has been made possible by current developments in genetics, immunology, and data analytics. Within the context of …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 32–47 Read article
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Dasatinib Induced Pulmonary Hypertension
Abstract: Dasatinib (Das) is a second-generation tyrosine kinase inhibitor that is used in the treatment of chronic myelogenous leukemia (CML) in patients who are resistant or intolerant to imatinib, as well as in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) patients. Dasatinib-induced pulmonary arterial hypertension (PAH) is a known but rare adverse effect of dasatinib and is grouped under Group-1 PAH. The mechanism of PAH development is not fully known, but …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 92–95 Read article