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206 articles for “coupling effect”
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Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 33–47 Read article
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Hierarchical Computational Modeling of Physical Structure Across Quark, Nuclear, and Atomic Scales
Abstract: We present a modular, multi-scale computational framework that integrates physical modeling and visualization across quark, nuclear, and atomic scales within a unified pipeline. Developed to address the traditional fragmentation between sub-nucleonic, nuclear, and electronic representations, the system provides a continuous data flow and visualization bridge spanning from femtometers to ångströms. The framework consists of three primary modules: a particle-level module illustrating nucleons as confined quark-triplets with effective flux-tube geometries; a …
Published in Research & Reviews : Journal of Physics · Vol. 15, Issue 1, 2026 · pp. 38–53 Read article
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Investigating Temperature Effects on Thermal Analysis of Composite Heat Pipes with Diverse Geometrical Configurations
Abstract: As the demand for efficient heat dissipation technologies continues to surge, understanding the intricate interplay between temperature variations and the thermal performance of heat pipes assumes paramount importance. This study investigates the impact of temperature fluctuations on the thermal behaviour of heat pipes with diverse geometric configurations. A comprehensive analysis is conducted utilizing advanced computational simulations coupled with experimental validation techniques. Heat pipes are an innovative heat transfer device with …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 20–34 Read article
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Holistic integrated approach of designing a satellite town: Introducing theories of environmental parameters like pollution free, circular economy and sustainability
Abstract: Urban regions are quite challenging to restore the quality of environment at the global level as well as posing serious threat to climatic changes. This fact is demonstrated on the grounds that around 70% of the carbon footprint is contributed from the urban sector. The authors of the present study have attempted to design a satellite town of population 50,000, partly to dilute the population density of main urban town …
Published in International Journal of Architectural Design and Planning · Vol. 3, Issue 1, 2025 · pp. 24–41 Read article
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Integrated Surface Water–Groundwater Dynamics: Implications for Pollution Pathways, Prevention, and Environmental Control
Abstract: Water resources worldwide are increasingly threatened by pollution pressures amplified by climate change and intensified human activities. The vulnerability of surface water and groundwater systems to contamination is strongly governed by their dynamic hydrologic connectivity, which is often overlooked in pollution prevention and control frameworks. Rising global temperatures, altered precipitation regimes, land-use change, and intensified abstraction patterns modify recharge processes, flow paths, and contaminant transport mechanisms across environmental landscapes. This …
Published in International Journal of Pollution: Prevention & Control · Vol. 4, Issue 1, 2026 · pp. 34–40 Read article
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Revolutionizing Nutrient Care: Trends, Tech, and Monitoring Innovations – A Comprehensive Review
Abstract: Nutrition plays a pivotal role in human health, encompassing a wide spectrum of nutrients crucial for bodily functions. Nutrients are typically divided into two categories: macronutrients and micronutrients, and people often use dietary supplements to augment their intake of these essential elements. However, the use of such supplements can have both benefits and risks, necessitating careful monitoring and prescription. This review highlights recent advancements in the monitoring of nutrients, with …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 10, Issue 2, 2023 · pp. 6–16 Read article
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Review on Strengthening & Retrofitting of RCC & Masonry Bridge Structure with Analytical Modelling of Sensor Data for the Durability of Bridge Structure
Abstract: In later a long time, monstrous advancement in Structural Health Monitoring (SHM) of bridges makes a difference address the life span and unwavering quality of bridge structure at differentiating stages of their benefit life. This article gives a point-by-point understanding of bridge observing, and it centers on sensors utilized and all sorts of harm location (strain, Displacement, acceleration, and temperature) concurring to bridge nature (scour, suspender failure, disconnection of bolt …
Published in Trends in Transport Engineering and Applications · Vol. 9, Issue 3, 2022 · pp. 16–23 Read article
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Design and Implementation of Solar Energy Conservation System for Societal Applications
Abstract: AbstractEnvironmental concerns and escalating demand for energy, coupled with progress in renewable energy technologies are creating new opportunities for the utilization of renewable energy resources. Solar energy is most abundant and clean of all energy resources till today. Here we built a solar energy controller system for effective control and cater the needs of different societal applications. Photovoltaic technology is one of the finest ways to harness the solar power …
Published in Journal of Electronic Design Technology · Vol. 11, Issue 2, 2020 · pp. 7–12 Read article
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Is low-intensity pulsed ultrasound effective in treatment of tibial nonunion?
Abstract: Background: Nonunions have been mainly treated with invasive methods by adequate mechanical stability and provision of biological environment leading to bone healing rate of 68%-96%, however, with inherent risks and complications. As an alternative to surgical interventions, low-intensity pulsed ultrasound (LIPUS), a biophysical method has been emerged. We aimed to prospectively compare the clinical and functional outcomes between two groups treated with LIPUS and capacitively coupled electric fields (CCEFs) for …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 3, 2022 · pp. 1–5 Read article
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A Study on AI-Enhanced Environmental Toxicology: Sensor-Driven Predictive Framework
Abstract: Traditional environmental toxicology relies heavily on labor-intensive, often retrospective, sampling and analysis, limiting our understanding of dynamic pollutant behaviors and their real-time impact on ecosystems and human health. This study presents a novel, integrated framework leveraging advanced sensor networks and artificial intelligence (AI) to revolutionize the monitoring, assessment, and predictive modeling of environmental contaminants. We deployed a sophisticated array of multi-parameter sensors (e.g., electrochemical, optical, biosensors for heavy metals, organic …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 3, 2025 Read article
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Nitrosamine Accumulation, Processing Variables, and Indigenous Plant Inhibitors in Nigerian Traditionally Processed Meats
Abstract: N-nitrosamines are classified as probable or possible human carcinogens by the International Agency for Research on Cancer. Carcinogenic N-nitrosamines — principally N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) — are formed in abundance during the preparation of widely consumed Nigerian traditional processed meats including suya, kilishi, and balangu. This original investigation combined a six geopolitical zone of Nigerian market survey with laboratory-controlled model system experiments, effects of processing parameters on N-Nitrosamine formation …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 61–72 Read article
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Determination of Free Chlorine Water Content in Jalandhar City Using Colorimeter
Abstract: Water is the ultimate source of life on this universe. Water is vital for the survival of humans, animals, and plants, and the issue of freshwater is becoming increasingly critical in society. With the human body composed of 64% water, contaminated water, inadequate waste disposal, and poor water management contribute to severe public health issues such as cholera, typhoid, and malaria annually. Globally, the quality and quantity of water are …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 1, 2024 · pp. 1–5 Read article
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A Comprehensive Review of CNN-Based Framework for Multi-Sign Detection of Diabetic Retinopathy in Fundus Images Using Public Datasets
Abstract: Diabetic retinopathy (DR) is one of the main causes of vision impairment. Blindness prevention and effective treatment depend on early detection. A thorough deep learning-based framework for the automatic segmentation and simultaneous detection of exudates, hemorrhages, and microaneurysms – three important DR indicators – from retinal fundus images is presented in this work. These three pathological signs’ corresponding annotated image patches, along with background (no-sign) areas, were used to train …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 14–23 Read article
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Parametric Optimization of Tool Wear Rate in Side Flushing form of Die Sink EDM of EN-31 Die Steel
Abstract: Electrical discharge machining (EDM) is one of the most extensively used non-conventional material removal processes for manufacturing geometrically complex or hard material parts that are extremely difficult to machine by conventional machining process. EDM researchers have concentrated on achieving faster and more efficient metal removal rate coupled with a reduction in tool wear and improved surface characteristics. In this paper, the operating performance measures of side flushing type of electrical …
Published in Journal of Materials & Metallurgical Engineering · Vol. 1, Issue 1-3, 2011 · pp. 72–80 Read article
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Review on Algae Biodiesel Production: A Strategy to Enhance Future
Abstract: The quest for cleaner and renewable energy sources has propelled the interest in the production of biodiesel from algae. Algae, due to their high oil content and fast growth rate, present a promising feedstock for the production of biodiesel, especially since they can be cultivated on non-arable land and with seawater or wastewater. Algae biodiesel offers the advantage of being compatible with current diesel engines without any need for modification, …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 23–30 Read article
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Modeling and Simulation of Radiative MHD Casson-Type Polymer Composite Flow over a Porous Wedge with Variable Thermal Source and Sink
Abstract: This study presents a numerical investigation of the radiative magnetohydrodynamic (MHD) flow and heat transfer characteristics of a Casson-type polymer fluid over a moving and extending porous wedge under the influence of a spatially varying heat source and sink. The Casson fluid model, representing a class of viscoplastic polymeric materials, is analyzed within the MHD framework to explore the combined effects of magnetic field intensity, rheological behavior, and porous medium …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 837–850 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 · pp. 1–14 Read article
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Quantum Computation in the Brain and Emergence of Unperturbed Mind Due to Inductive BIS Load
Abstract: Abstract“Solitons”, are comprised of a loosely coupled coherent system of subquantum entities. Thiscoherent solitonic system of loosely coupled entities can be viewed as a partial description ofconsciousness. BIS stands for breakdown of integrated system. It is of three kinds: resistive,capacitative and inductive. In our present paper we will study the behavior of unperturbedmind due to strong inductive BIS processes.Keywords: BIS effect, quantum computation, microtubules, quantum zeno effect, solitonsCite this ArticleSobinder …
Published in Research & Reviews : Journal of Physics · Vol. 4, Issue 3, 2015 · pp. 27–31 Read article
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Comparative Analysis of FD-DMDG SON MOSFET over FD DMDG SOI MOSFET
Abstract: AbstractIn the recent past, Silicon-on-Insulator (SOI) shows better device performance in comparison to bulk Silicon devices but it still suffers from different short channel effects (SCEs). Recently a structure, Silicon on Nothing (SON), has been suggested and investigated. It is structured to be capable of substantial reduction of SCEs and present better electrical characteristics in comparison to SOI. The absence of the buried layer results in the reduced electrostatic coupling …
Published in Journal of Electronic Design Technology · Vol. 9, Issue 1, 2018 · pp. 9–16 Read article