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230 articles for “antimicrobial effects”
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THE BURDEN OF EMPIRICAL THERAPY: ANALYZING THE PREDOMINANCE OF BROAD-SPECTRUM ANTIBIOTIC USAGE IN LOWER RESPIRATORY TRACT INFECTIONS
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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A Review on Loading Methodologies of Active Aromatic Substance into Biopolymers
Abstract: Biopolymer-based films are increasingly being studied as sustainable alternatives to conventional packaging materials due to their biodegradability, renewability, and potential for functionalization. There are several natural polymers in the category of biopolymers such as soy protein, zein, cellulose, chitosan, and several other biodegradable synthetic polymers such as polylactic acid and polycaprolactone. However, these often show limitations in barrier properties, mechanical strength, and resistance to microbial contamination. To overcome these drawbacks, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 9–13 Read article
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Evaluation of Respiratory Tract Infectious Pathogens and Their Antibiotic Sensitivity in a South Indian Hospital
Abstract: This study is aimed to determine prevalence of infectious agents causing respiratory tract infection (RTIs) and their sensitivity to antibiotics. The study was conducted in Rajiv Gandhi Institute of Medical Sciences of Kadapa in Andhra Pradesh in South India from December 2013 to May 2014. Patients who were clinically suspected of RTIs were included in the study. Sputum, throat swab and pleural fluid samples were collected aseptically from the patients …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 3, 2014 · pp. 18–25 Read article
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Review on Formulation and Evaluation of Herbal Gel of Moringa oleifera and Aloe vera for management of acne
Abstract: Acne vulgaris is a prevalent chronic inflammatory disorder of the pilosebaceous units, characterized by excessive sebum production, follicular hyperkeratinization, bacterial colonization, and inflammation. Conventional therapies often result in side effects and the development of drug resistance, prompting the exploration of natural alternatives. This review highlights the potential of Moringa oleifera and Aloe vera in acne management via topical drug delivery systems (TDDS). Moringa oleifera is rich in bioactive compounds such …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 10–16 Read article
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Biomedical Coatings: Surface Engineering for Enhanced Biocompatibility and Performance
Abstract: Biomedical coatings have become essential in modern healthcare, significantly improving the performance, durability, and biocompatibility of medical implants and devices. These coatings serve multiple functions, including reducing infection risks, enhancing osseointegration, promoting tissue integration, and enabling localized drug delivery. Advances in surface engineering have led to the development of innovative coatings with superior properties such as antimicrobial resistance, bioactivity, and controlled biodegradation. Various materials are employed in biomedical coatings, including …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 8–15 Read article
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Fabrics and medical devices (catheters) coated with Zn doped CuO nanoparticles kills micro-oganisms and provide healthy environment
Abstract: These days, drug resistance by microorganisms is a major challenge in the field of medicinal chemistry. Most of the familiar antibiotics turnout to be of no impact in curbing the proliferation of microorganism (bacteria, virus and fungus). To address the issue of multi-drug resistance (MDR) and extremely drug resistance (EDR) in microorganisms that cause various health complications, like the dental decay, biofilm formation, foul smell, delayed wound healing, aggravation of …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 1, 2025 · pp. 1–9 Read article
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Synthesis and Characterization of Silver Nanoparticles by using Aqueous Leaf Extract of Tecomella Undulata (SM.) seem. and their Antibacterial Properties
Abstract: Abstract The efficient protocol for bio-synthesis of silver nanoparticles (AgNPs) using Tecomella undulata leaves was developed. The present study revealed that bio-active compounds and secondary metabolites present in the aqueous extract function as stabilizing agent for AgNPs. UV-Visible spectro-analysis and FTIR confirm the presence of bioactive compounds and TEM, EDX and XRD studies confirm the crystalline nature, structure and surface morphology of silver nanoparticles produced from the plant Tecomella undulata. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 2, 2020 · pp. 5–13 Read article
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Comparison Study of Non-Alcoholic Sanitizer and Alcohol Based Sanitizer
Abstract: Hand sanitizer is the best choice to maintain the hand hygiene and stopping the spread of infectious diseases. The active ingredient in traditional hand sanitizers is usually alcohol, but worries about flammability, skin irritation, and possible abuse have prompted the creation and growing popularity of alcohol-free substitutes. The purpose of this review is to objectively assess the safety, effectiveness, and usefulness of alcohol-free hand sanitizers. To successfully eradicate germs, alcohol-free …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
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Carica papaya Assisted Biosynthesis of Silver Nanoparticles with Antimicrobial Activity
Abstract: Nanoparticles are used immensely due to its small size, orientation, physical properties, which are reportedly shown to change the performance of any other material which is in contact with these tiny particles. These particles can be prepared easily by different chemical, physical, and biological approaches. But the biological approach is the most emerging approach of preparation, because, this method is easier than the other methods, ecofriendly and less time consuming. …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 2, 2015 · pp. 1–3 Read article
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Green synthesis of Silver nanoparticles using leaf extract of Cyclea peltata and its Antimicrobial activity
Abstract: Nanotechnology is a reliable and enabling environment friendly process for the synthesis of nanoscale particles of structures ranging from approximately 1- 100 nm. Since the chemical synthesis of nanoparticles have adverse effect in medical applications, green synthesis of nanoparticles is in a huge need. Silver is one of the substances used in nanoformulation. Silver nanoparticles were successfully synthesized through silver nitrate through a simple green route using the clean, dried, …
Published in Research & Reviews : Journal of Botany · Vol. 8, Issue 2, 2019 · pp. 1–6 Read article
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A Study Showing the Antagonistic Effect of Lactobacillus casei Against Candida albicans
Abstract: Probiotic strain, Lactobacillus casei was isolated from the probiotic suspension named as Yakult. Strains of Candida albicans were collected from the S.N. Medical College, Agra, India. The antagonistic effect of L. casei against C. albicans was dictated by utilizing the Kirby Bauer disc diffusion technique. Maximum zone of hindrance was estimated by the serial suspension of M.F.S. ≠1.0 against C.albicans and the medium zone of hindrance was seen in the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 2, 2018 · pp. 35–39 Read article
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Barg-e-Tulsi (Ocimum sanctum Linn.) in Unani Medicine: Bridging Classical Therapeutics with Contemporary Pharmacological Evidence
Abstract: In the Unani System of Medicine (USM), Barg-e-Tulsi (Ocimum sanctum Linn.), commonly known as Tulsi or Holy Basil, is a highly valued medicinal herb that has been extensively used for centuries in the prevention and treatment of various ailments. It occupies an important place in traditional Unani therapeutics due to its broad spectrum of medicinal properties and its effectiveness in managing respiratory, gastrointestinal, neurological, and infectious disorders. Classical Unani scholars …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 · pp. 20–29 Read article
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Antibiotic Resistance Patterns of Helicobacter pylori in Africa
Abstract: To eradicate Helicobacter pylori (H. pylori), antibiotic therapy must be adapted to the local resistance patterns. However, the epidemiology of drug resistance pattern of H. pylori is poorly documented in Africa. Therefore, the present review is aimed to review the prevalence of antibiotic resistant H. pylori from previous studies in Africa. A computerized English language literature search of PubMed, MEDLINE and Google Scholar was performed in January 2016. Only 11 …
Published in Research and Reviews: A Journal of Medicine · Vol. 7, Issue 1, 2017 · pp. 4–9 Read article
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Anthocyanin: Structure, Synthesis and its Beneficial Role in Health
Abstract: Anthocyanins, are chemically diverse class of secondary metabolites that color most flowers and fruits. They consist of three aromatic rings that can be substituted with hydroxyl, sugar, acyl and methyl groups in a variety of patterns, depending on the plant species. There are basically six types of anthocyanins commonly found in plants. The biosynthesis of anthocyanins start with the pentose-phosphate pathway, continues with shikimate pathway, and follows the pathway of …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 5, Issue 1, 2016 · pp. 45–55 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article
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Insilico Structural Analysis and Homology Modeling of Crustin Protein from Fiddler Crab Species
Abstract: In terms of biomass and ecological or economic importance, the crustacea are the largest, most noticeable, and possibly, the most significance group of marine or aquatic arthropods. Because of their enormous commercial value and the necessity to prevent disease outbreaks in the shellfish aquaculture industry, decapods are the experimental animals of choice for practically all biological studies involving immune responses. Antimicrobial host-defense peptides (AMPs) are major components of metazoan immunity, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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Heterocyclic Compounds in Thin Film Coatings: A Review on Anticorrosion and Antimicrobial Properties.
Abstract: Heterocyclic compounds have gained significant attention in thin film coatings due to their exceptional chemical versatility and functional properties. These compounds, characterized by the presence of heteroatoms in their ring structures, play a crucial role in enhancing the anticorrosion and antimicrobial performance of protective coatings. This review explores the recent advancements in the application of heterocyclic compounds for corrosion resistance and microbial inhibition, emphasizing their mechanisms of action, effectiveness, and …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 16–21 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Determination of antimicrobial potential of Bacillus clausii against Candida albicans
Abstract: Bacillus clausii is a universally occurring beneficial bacteria.It is gram-positive, spore forming, lactic acid producing probiotic. Bacillus clausii are support the growth of friendly bacteria and help maintain a healthy balance of microflora in the intestinal environment. A study was carried out on inhibitory effects of Bacillus clausii on growth of some pathogens isolated from clinical specimens of pathogens selected for this study were Candida albicans isolated from blood and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 1, 2020 · pp. 1–4 Read article
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Application of Natural and Synthetic Polymer-Based Disintegrants in the Design of Fast Dissolving Cefuroxime Axetil Tablet Composites
Abstract: The current paper examines how natural and synthetic polymer-based disintegrants can be used to design fast-soluble types of tablet composites. A model drug was chosen and tablets were prepared by the direct compression method using different polymeric excipients, such as guar gum, locust bean gum, sodium starch glycolate (SSG) and cross povidone. Eight formulations were prepared and tested on the basis of critical material and performance characteristics including thickness, hardness, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1348–1360 Read article