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161 articles for “Therapeutic Actions”
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Nature’s Pharmacy: Plant-Based Antifungal Agents and Their Therapeutic Potential
Abstract: Antifungal resistance has increased dramatically over the last 10 years, causing serious problems for healthcare because of higher morbidity and death. The urgent need for new treatments is highlighted by the scarcity of effective antifungal medications, their toxicity, and the rise of resistant strains. Since many plants have bioactive secondary metabolites with strong antifungal qualities, including alkaloids, flavonoids, terpenoids, phenolics, and saponins, ethnobotanical sources offer a viable path. Plants with …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 1–7 Read article
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Effect of Unani Formulation in the Management of Non-Healing Ulcer – A Case Report
Abstract: Background and Aim: A non-healing ulcer (Qurooh-e-Aseerul-Indemal) of the foot is characterized by a persistent deterioration of the epidermal and dermal layers of the skin on the foot, continuing for more than six weeks without showing signs of recovery. Non-healing ulcers represent a significant global health challenge, markedly affecting patient well-being and imposing a considerable burden on their families. Global prevalence ranges between 1.9% to 13.1%, while in India, the …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 7–12 Read article
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Therapeutic Potential of Sheetraj (Plumbago Zeylanica Linn.)-A Potent Drug of Unani Medicine
Abstract: Plumbago zeylanica also known as Sheetraj or Chitraka belongs to the family Plumbaginaceae. It is one of the important medicinal plants which is used worldwide due to its therapeutic value. Therefore, this work carried out on Sheetraj has been, gathered, analyzed and reviewed using references from different sources like classical text and indexed journals. The aim of this review is to provide data or comprehensive information related to the chemical …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 2, 2022 · pp. 40–51 Read article
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Nanorobots: The Fight against Cholesterol
Abstract: Cardiovascular disease (CVD) rests leading reason of death globally, with atherosclerosis, the buildup of plaque in arteries, playing a central role. Current treatment strategies, including lifestyle changes and medications, often fall short in completely reversing or preventing the progression of atherosclerosis. This has spurred the exploration of innovative approaches, with nanorobotics emerging as a promising avenue for targeted plaque control and high-density lipoprotein (HDL) enhancement. This article discusses how nanorobots …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 2, 2025 · pp. 23–32 Read article
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Antibiotic Resistance in Microbes: History, Mechanisms, Therapeutic Approaches, and Strategies for Mitigation
Abstract: The global emergence of clinically significant antibiotic resistance is increasingly linked to the environment. Antimicrobials, metals, and biocides are just a few of the substances that are released into the environment through paths that are regulated by environmental regulators. Consequently, environmental regulators ought to be heavily involved in developing national and international antimicrobial resistance (AMR) measures. Antimicrobial compounds from pharmaceutical waste, agricultural runoff, and wastewater discharge contribute to the spread …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–11 Read article
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Design And Evaluation Of Meloxicam Tablet For Colon Cancer
Abstract: Meloxicam, recognized as a preferential COX-2 inhibitor, has emerged as a promising chemopreventive agent for colorectal cancer. Leveraging its local and targeted action on the colon, Meloxicam proves to be a formidable component in the prevention of colorectal malignancies. This study aims to innovate by formulating and evaluating a targeted tablet delivery system for Meloxicam, emphasizing site-specific and instant drug release in the colon, thereby maximizing its therapeutic efficacy in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 1–7 Read article
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Post Halela Zard (Terminalia chebula Retz.): A Review on Medicinal Utility from the Perspective of Unani Medicine
Abstract: Halela Zard (Terminalia chebula Retz.), commonly known as Haritaki in Sanskrit and Chebulic Myrobalan in English, is a cornerstone of Unani pharmacotherapy due to its remarkable therapeutic versatility. The dried pericarp of its fruit has been extensively employed in traditional medicine for the treatment of a wide spectrum of ailments, ranging from digestive disturbances to chronic systemic disorders. This review aims to present a comprehensive overview of Halela Zard by …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 19–26 Read article
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From Clinic Formulation to Development of Acebrophylline
Abstract: Acebrophylline, a commonly utilized bronchodilator with anti-inflammatory properties, has become a key therapeutic option for managing respiratory conditions like asthma, chronic obstructive pulmonary disease (COPD), and chronic bronchitis. This review explores the journey of Acebrophylline from its clinic formulation to its development and commercialization, focusing on the key aspects of formulation strategies, pharmacological properties, and regulatory considerations. The drug’s dual mechanism of action, which involves both bronchodilation and anti-inflammatory effects, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 35–48 Read article
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Comprehensive Evaluation of Herbal Plants for Cancer Prevention
Abstract: Since cancer continues to be a major cause of morbidity and death globally, effective prevention measures are desperately needed. As the world’s cancer burden increases, interest in alternative cancer prevention methods, particularly the use of herbal medicine, is also increasing. With their rich history and diverse phytochemical composition, medicinal plants provide a great opportunity for the development of disease prevention strategies. This review explores the potential of various plants, including …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 01–07 Read article
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Patents on Gastroretentive Drug Delivery System: An Overview
Abstract: Background: Conventional oral dosage forms have poor bioavailability and recurrent dosing of the drug is needed to maintain the effective therapeutic concentration in the body. It may lead to poor patient compliance and fluctuations in the plasma level of drug especially in the chronic diseases and disorders. Origin: In outlook of this, to enhance the efficiency and bioavailability of the drug, gastroretentive drug delivery system is developed which can prolong …
Published in Trends in Drug Delivery · Vol. 8, Issue 1, 2023 · pp. 22–30 Read article
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Toxicological Profiling and Safety Assessment of NASAT 2.0: A Conceptual Framework for Adaptive Nanoparticle Therapy in Rabies
Abstract: Rabies, caused by the highly neurotropic Rabies lyssavirus, remains one of the most enigmatic and universally lethal infectious diseases known to modern medicine. Once clinical symptoms manifest following successful neuroinvasion, the fatality rate approaches absolute certainty (approximately 99.9%), a staggering statistic that has remained largely unchallenged despite massive, concurrent advances in modern virology, critical care medicine, and cellular immunology. Current late-stage therapeutic protocols, most notably the widely debated Milwaukee Protocol, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 · pp. 1–19 Read article
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A Review on the Interconnection Between Drug Design and Controlled Drug Delivery Systems
Abstract: Drug discovery and delivery are two branches of science that have historically developed as independent areas of discovery – one focused on optimizing the properties of molecules for biological activity, and the other on controlling the rate, site, and duration for drug release. However, in contemporary pharmacy, these two areas have merged into a single integrated approach – where drug discovery and delivery strategies co-influence each other at each point …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 47–52 Read article
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Indian Medicinal Plants used in Diabetes Mellitus: An Overview
Abstract: Diabetes mellitus (DM) is the commonest endocrine disorder that affects more than 100 million people worldwide (6% of the population). It is caused by the deficiency or ineffective production of insulin by pancreas which results in increase or decrease in concentrations of glucose in the blood. It is found to damage many of the body systems, particularly the blood vessels and nerves both insulin-dependent DM (IDDM) and non-insulin dependent DM …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 1, 2017 · pp. 1–10 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 62–79 Read article
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Phyto-Pharmacognostical Study of Zornia Gibbosa Span (Samyojaki)
Abstract: Recent survey shows that the plants extinction are occurring at rates hundreds of times higher than natural background rates, and 15,000 species of medicinal plants are now threatened. Under such circumstances the drugs which are abundantly available, common and cost-effective should be encouraged to control the extensive overuse of few classical drugs. Thus preventing them from verge of extinction and also reducing the chances of adulteration. Looking at the need …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 3, 2013 · pp. 24–32 Read article
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Cannabinoids as Nutritional Supplements: Exploring The Potential Health Benefits and Regulatory Landscape
Abstract: Cannabinoids, the bioactive compounds derived from the Cannabis sativa plant, have garnered increasing interest for their potential role as nutritional supplements. This abstract provides a succinct overview of cannabinoids as nutritional supplements. This review delves into the multifaceted aspects of cannabinoids, particularly their interaction with the endocannabinoid system (ECS) and their potential health benefits. The exploration begins by elucidating the intricate relationship between cannabinoids and the ECS, a vital regulatory …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 48–53 Read article
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Nanotechnology in Surgical Drains: Reducing Infections and Promoting Healing Post-Surgery
Abstract: Surgical drains are widely used in postoperative care to evacuate accumulated fluids, minimize dead space, and reduce complications such as hematoma and seroma formation. Despite their clinical importance, conventional drains are frequently associated with retrograde bacterial migration, biofilm formation, and increased risk of surgical site infections (SSIs), which contribute significantly to postoperative morbidity and prolonged hospital stay. Recent advancements in nanotechnology have enabled the development of nano-functionalized surgical drains with …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 2, 2026 · pp. 54–67 Read article
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Unlocking Potential: Capecitabine’s Evolution as an Anticancer Wonder Drug
Abstract: Capecitabine, a precursor to 5-fluorouracil (5-FU), is Anticancer Drug in treating solid tumors like colorectal, breast, and gastric cancers. Its mechanism involves converting to 5-FU mainly within tumor cells, reducing toxicity while maximizing effectiveness. Besides being effective alone, it is also valuable in combination therapies, showcasing its versatility in cancer treatment. This review explores the transformative journey of capecitabine as a pivotal anticancer drug. Beginning with an introduction to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
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Preparation and Characterization of Clay-Based Hybrid Membranes for Antibacterial Biodegradable Polymer Wound Dressings
Abstract: Recent developments in the field of polymer chemistry have resulted in many new forms of Hybrid polymer. This has further revolutionized the application of polymer chemistry in numerous fields. In this research, we manufactured clay-based hybrid membrane by adding clay to the biodegradable matrix of chitosan polymer. It is widely known that microbial and pathogenic organisms are responsible for wound hampering infections such as impetigo. They can spread in bodily …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 13–20 Read article
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Rivaroxaban: A Comprehensive Review of an Anticoagulant Revolution
Abstract: Rivaroxaban, a prominent direct oral anticoagulant (DOAC), has garnered attention for its pivotal role in preventing and treating thromboembolic diseases. Its introduction into clinical practice has marked a significant advancement in anticoagulant therapy. The mechanism of action of rivaroxaban involves selective inhibition of factor Xa, a crucial component in the coagulation cascade. This targeted approach distinguishes it from traditional anticoagulant and contributes to its efficacy. The significance of rivaroxaban lies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 17–23 Read article