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191 articles for “Pharmaceutical activities.”
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A Review to Explore Pharmaceutical and Pharmacological Potential of Caffeine Molecule
Abstract: Caffeine an adenosine like molecule has attracted interest of many researchers. More than eighty percent of world population consumes caffeinated products. The exponential growth of caffeine is due to its medicinal uses, its availability food products as beverages and other OTC products. More and more sports persons are using it as stimulant and energy booster. Caffeine is reported to possess anti-inflammatory properties and anti-oxidant activity. Many of the over the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 2, 2020 · pp. 1–8 Read article
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Enhancing the Bioavailability of Polyphenols: A Comprehensive Review
Abstract: The polyphenolic compounds are abundantly found in different plant parts including fruits, leaves, stem and seeds, and are known for possessing a wide range of biological activities. These include antioxidant, antimicrobial, anti-inflammatory, anticancer, antidiabetic, cardioprotective, and neuroprotective effects. Their functional relation with their structure highlights the significant therapeutic potential. As a result, the polyphenols are being further being exploited for applications in functional foods, pharmaceuticals, and targeted drug delivery. Despite …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 2, 2026 · pp. 37–51 Read article
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Dieto-Therapy (Ilaj-bil-ghiza) in Unani System of Medicine: From Concept to Practice in the Management of Non-communicable Diseases
Abstract: Unani physicians paid a great attention towards ilaj-bil-ghiza (dieto-therapy). They used to treat a number of ailments by alteration in quantity and/or quality of Ghiza. Their knowledge about its nutritive as well as its pharmacological activity was vast as evident from the Unani classical literature. The classification of Unani drugs is based on medicinal and nutritive values. The former is known as dawa and later is ghiza. Further, a combination …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 4, Issue 2, 2015 · pp. 54–59 Read article
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Hepatoprotective Activity of Japanese Cedar (Cryptomeria japonica) against Carbon Tetrachloride Induced Toxicity
Abstract: Liver is a vital organ which plays a major role in metabolism and excretion of xenobiotics from the body. Liver injury or liver dysfunction is a major health problem that challenges not only health care professionals but also the pharmaceutical industry and drug regulatory agencies. Liver cell injury caused by various toxic chemicals and excessive alcohol consumption and microbes is well studied. The available synthetic drugs to treat liver disorders …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 6, Issue 2, 2016 · pp. 6–9 Read article
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A Thorough Analysis of Herbal and Synthetic Methods for Treating Peptic Ulcers
Abstract: Many people are afflicted with ulcers, a common gastrointestinal disorder. In essence, they are inflammatory lesions that form in the digestive tract's skin or mucous membrane lining. An imbalance between preventive and damaging factors—either from reduced mucosal defences or from increased aggressive elements—leads to ulcer development. Their development is influenced by a number of variables, including as stress, poor eating habits, and long-term pharmaceutical use. The word "peptic ulcers" refers …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 55–71 Read article
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Advanced Water Purification Techniques for Sustainable Clean Water Management: A Comprehensive Review
Abstract: The growing global demand for safe drinking water, coupled with increasing pollution from industrialization, urbanization, and agricultural activities, has intensified the need for efficient and sustainable water purification technologies. Conventional water treatment processes often fail to remove emerging contaminants such as pharmaceuticals, microplastics, endocrine-disrupting compounds, and heavy metals. Advanced water purification technologies—including membrane filtration, advanced oxidation processes (AOPs), nanotechnology-based adsorbents, photocatalysis, electrochemical treatment, and bio-inspired purification systems—have emerged as promising …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 1, 2026 · pp. 47–52 Read article
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Catalytic Activity Advancements in Organometallic Chemistry
Abstract: Organometallic chemistry is essential to catalysis and synthesis, helping to shape a wide range of chemical reactions. The study of the interactions between organic compounds and metal elements is known as organometallic chemistry. Modern synthetic chemistry and catalysis have been greatly influenced by the field of organometallic chemistry. It entails the investigation of substances that have metal-carbon bonds because they can have special catalytic and reactive qualities. Applications for these …
Published in Journal of Catalyst & Catalysis · Vol. 10, Issue 2, 2023 · pp. 10–25 Read article
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Accelerating Drug Discovery with AI: Transforming the Pharmaceutical Pipeline
Abstract: The revolutionary potential of artificial intelligence (AI) is examined in this essay the pharmaceutical industry, highlighting its application across the drug development lifecycle. Artificial Intelligence, specifically via deep learning models and machine learning (ML) such as GANs, RNNs, and transformers, enhances drug discovery, formulation, toxicity prediction, and clinical trials. It streamlines processes like identification of targets, virtual screening, modelling of structure-activity relationships, and medication repurposing. AI is also employed in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 77–84 Read article
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Spectrophotometric Method for the Estimation of Levosulpiride in Bulk Drug and Formulations
Abstract: Levosulpiride having D2-dopamine receptor antagonistic activity gives ant depressive and antiulcer effect. There are three new simple accurate, rapid, economical and precise procedures for spectrophotometric estimation of Levosulpiride in bulk and pharmaceutical formulation. Levosulpiride was estimated at 291.5 nm in 0.1 N NaOH, 290 nm in 0.1 N HCl and 292.5 nm in 6.8 phosphate buffer. Linearity range was found to be 10–50 µg/mL in all the three methods. The …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 1, 2015 · pp. 19–23 Read article
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Key Regulatory Requirements and Guidelines for the Registration of a Drug in Canada
Abstract: Drug product registration is an important step in the process of a drug development from raw material to finished product to making it available to the public. Drug regulatory authorities play an important role in this process. Health Canada is the regulatory authority in Canada which manages the drug submission and approval of drug product in Canada. The guidelines from the Food and Drugs Act and Regulations for drug products …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 2, 2015 · pp. 28–37 Read article
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Biological Classification System (BCS), its Significance on Dissolution Study and Application in Dosage Form Development
Abstract: Bioavailability (BA) has an important role in new drug discovery and product development in pharmaceutical field. The solubility and permeability are important parameters of biopharmaceutics and have central role in lead optimization by controlling the pharmacokinetic parameters to give better therapeutic activity. Biopharmaceutical classification system (BCS) is a drug development tool that is based on correlation of solubility and permeability with bioavailability of drug in human body. The principles of …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 4, Issue 2, 2017 · pp. 1–16 Read article
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Design, Synthesis and Pharmacological Evaluation of Pyrazoline Substituted Benzimidazole Derivatives as Antibacterial and Antifungal Agents
Abstract: Background: Benzimidazoles are important heterocyclic compounds possessing a variety of biological activities such as anticancer, antioxidant, antiinflammatory, analgesic, anti-viral, anti-bacterial, anti-fungal and hypoglycemic activities. Pyrazolines are used as antitumor, immunosuppressive, antibacterial and anti tubercular agents. Aim : The present research focused on incorporating pyrazoline nucleus into benzimidazole nucleus to form a potent antibacterial and antifungal agent. Method: The in silico design of novel pyrazoline substituted benzimidazole derivatives was done using …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 3, 2020 · pp. 29–41 Read article
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METAL NANOPARTICLE: SYNTHESIS, PROPERTIES, AND THEIR DERMATOLOGICAL AND COSMETIC IMPACTS
Abstract: Nanoparticles (NPs) are materials with dimensions under 100 nm and various shapes, such as spheres and rods. Their advancement offers transformative potential in medical and healthcare fields. The increased application of NPs across molecular biology, chemistry, medicine, and material science reflects their growing importance. Due to their large surface area, NPs enhance substance delivery through the skin, benefiting cosmetic applications by improving penetration, efficacy, and targeted delivery of active ingredients.With …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article
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Synthesis, Characterization and Evaluation of Pyridine derivatives
Abstract: Schiff bases, a class of organic compounds, have garnered significant attention due to their diverse applications in various fields such as pharmaceuticals, materials science, and coordination chemistry. This study provides a comprehensive overview of the synthesis of Schiff bases amino pyridine derivatives and aromatic ketones along with their anti-microbial activity. Method: The synthesis of Schiff bases primarily involves the condensation reaction between a primary amine and a carbonyl compound (ketone) …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 35–48 Read article
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Synthesis of Lawsonia Inermis (Henna) Carbon Supported AgO Nanocomposite, Characterizations and Photocatalytic Activity Studies
Abstract: Synthesis of Carbon supported AgO nanocomposite is reported for first time. Henna carbon was successfully synthesized from henna leaf. Bare AgO and C-AgO nanocomposites are effectively made using precipitation method. The synthesised composites structural, morphological, and optical properties are assessed using FT-IR, XRD, FE-SEM, UV-DRS, and PL techniques. FT-IR analysis proved that specific functional groups of synthesized materials. The uniform distribution of the composites is revealed in the FE-SEM. XRD …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 749–760 Read article
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RP-HPLC method for simultaneous determination of Drospirenone and Ethinylestradiol in Bulk and their Pharmaceutical dosage form
Abstract: Oral contraceptive is used to prevent the pregnancy which is contain hormones to block the release of eggs from the ovaries. Most of them contain estrogen and progesterone. Nowadays, usage of hormonal contraceptive is sharply enhancing; around 100 million of women worldwide are taking these drugs. With this drug fertility rate can be supressed as long as they want or plan their activity along with these drugs provide efficacy, reliability, …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 46–67 Read article
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Onepot Multi-component Synthesis, Characterization and Biological Applications of Dicationic Ionic Liquids
Abstract: A series of dicationic ionic liquids have been prepared and confirmed with FT-IR, 1H NMR,13C NMR,31P NMR as well as High resolution mass spectroscopy impact technique. The present methodology possesses more advantages such as high yields, simple procedure, short reaction times and mild conditions. All the synthesized compounds were evaluated for their antimicrobial activity based on zone of inhibition. The ionic liquid, 4-butane diaminium NI,NI,NI,N4,N4,N4 hexapropyl dibromide was exhibited remarkable …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 2, 2020 · pp. 16–39 Read article
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A Study on The Impact of Artificial Intelligence in Pharmaceuticals
Abstract: The main goal of artificial intelligence (AI) is to create intelligent modeling, which facilitates knowledge imagination, problem-solving, and decision-making. AI is becoming more and more significant in several pharmacy domains, including polypharmacology, hospital pharmacy, drug discovery, and drug delivery formulation development. Various types of artificial neural networks (ANNs), including deep neural networks (DNNs) and recurrent neural networks (RNNs), are utilized in the development of drug delivery formulations and in drug …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 1, 2025 · pp. 24–32 Read article
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The Therapeutic and Biotechnological Potential of Pogostemon benghalensis – A Comprehensive Review
Abstract: Pogostemon benghalensis is a fragrant perennial shrub belonging to the family Lamiaceae, widely distributed across tropical and subtropical regions of Asia. It has been extensively utilized in traditional and ethnomedicinal systems for the treatment of wounds, skin infections, fever, digestive disorders, inflammation, and respiratory ailments. The plant is also valued for its antiseptic, aphrodisiac, insect-repellent, and veterinary medicinal properties. Its leaves, roots, and essential oil are incorporated into herbal formulations, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 · pp. 55–63 Read article
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Pylorus Ligation Induced Gastric Ulcer Protection by Sesamum Indicum Ethanolic Seed Extract
Abstract: The present study was performed in pylorus ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 42–49 Read article