Search
1321 articles for “Method development”
-
Neuroimaging in Clinical Trials for Huntington’s Disease: Emerging Research Findings: The Advancement Directions and Implications
Abstract: Neuroimaging is very important in coordinating and conducting Huntington’s disease clinical trials as a tool in selecting patients, managing safety concerns, and assessing the benefits of interventions. This review presents the current uses and potential future uses of structural and functional magnetic resonance imaging (MRI), diffusion imaging, positron emission tomography (PET), proton magnetic resonance spectroscopy (MRS), perfusion imaging, and magneto encephalography (MEG) in HD trials. We describe how these modalities …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 32–44 Read article
-
A Review of Glass Fiber Reinforced Composite Materials - Advancements and Challenges
Abstract: The use of glass fiber reinforcement has transformed modern engineering by providing an exceptional balance of strength, lightweight characteristics, and adaptability. This comprehensive review synthesizes findings from over 150 scholarly articles to provide an in-depth analysis of glass fiber reinforcement across multiple sectors. The exploration covers its historical development, manufacturing processes, and diverse applications in aerospace, automotive, construction, marine, and renewable energy industries. Glass fiber’s exceptional strength-to-weight ratio, corrosion resistance, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 635–656 Read article
-
Integrating Human-Centric Principles into Machine Design: Ergonomic and Safety Enhancements in Mechanical Systems
Abstract: The integration of human-centric design (HCD) principles into mechanical systems has become increasingly critical in contemporary machine design. As machines become more complex and operate within high-interaction environments, the need for design strategies that prioritize human safety, usability, and comfort has intensified. This review explores how ergonomic insights, safety standards, and user experience (UX) considerations influence the physical configuration, control mechanisms, and operational safety of mechanical systems across industrial, healthcare, …
Published in Trends in Machine design · Vol. 12, Issue 2, 2025 · pp. 33–37 Read article
-
A Systematic Review on Peptic Ulcer Disease and its Pharmacological Treatment
Abstract: A chronic gastrointestinal condition known as Peptic Ulcer Disease (PUD) is typified by the formation of ulcers or mucosal erosions in the proximal duodenum and stomach. In the pathophysiology of PUD, the equilibrium between defensive processes like mucus and bicarbonate secretion, mucosal blood flow, and prostaglandin production, and aggressive factors such stomach acid secretion, pepsin activity, and Helicobacter pylori infection, is upset. Although stress and food have historically been blamed, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 76–84 Read article
-
Advancement in Biodegradable Equipment for Flexible and Sustainable Electronics
Abstract: Biodegradable electronics are a quickly developing area focused on reducing the environmental impact of traditional electronic waste by using materials that can break down naturally after use. These devices use eco-friendly polymers, nanocomposites, and bio-based materials that maintain electrical function temporarily before safely decomposing. Recent developments show the potential of plant-based polymers, conductive biodegradable composites, and transient materials that support flexible and wearable applications without causing long-term harm to the …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 2, 2025 · pp. 32–37 Read article
-
Integrated Perspectives on Fluid Mechanics and Energy Transport in Complex Flow Systems
Abstract: Fluid mechanics plays a central role in understanding the transport of mass, momentum, and energy in complex flow systems encountered in both natural and engineered environments. This review presents an integrated perspective on fluid behavior by combining fundamental principles with modern approaches to energy transport analysis. The study emphasizes the significance of conservation laws and their application to diverse flow regimes, including laminar, turbulent, compressible, and multiphase flows. Energy transport …
Published in Recent Trends in Fluid Mechanics · Vol. 13, Issue 1, 2026 · pp. 22–31 Read article
-
Biodegradable Polymer Nanocarriers Composites for Biomedical Applications
Abstract: Smart polymeric nanocarriers, or SPNs, have evolved into a fascinating means of delivering medications especially to cancer cells. By improving the efficacy of chemotherapeutic treatments while lowering their negative effects, they have achieved a significant progress in exact medicine. Made to respond to certain elements in the tumours microenvironment, such as enzymes, temperature, pH, and redox conditions, these nanocarriers this reaction to triggers guarantees the release of the medicine at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 293–305 Read article
-
Use of Claim-Evidence Reasoning Method in Schools to Enhance Women's Empowerment in Research
Abstract: Although today's women are literate, their level of science literacy is very low. If we want to increase the participation of women in research in the future, it should be implemented at the school level. Claim Evidence Reasoning is an effective method of teaching, that will help the students understand the concepts of science easily, build scientific literacy among them, increase their confidence, and increase their participation in research, which …
Published in International Journal of Education Sciences · Vol. 2, Issue 2, 2025 Read article
-
Design and Simulation of Low-power, High-speed Effective Area Mux Based One-bit Full Adder Using CMOS Technology
Abstract: Our findings reveal a novel kind of circuit capable of performing both XOR and XNOR operations in parallel. Power dissipation and delay are both greatly reduced in the proposed circuits due to their low output capacitance as well as minimal short-circuit power dissipation. We show six new hybrid 1-bit full-adder (FA) circuits that take use of the XOR-XNOR or XOR/XNOR gates' special full-swing function. Each potential circuit layout has both …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 1, Issue 1, 2023 · pp. 25–33 Read article
-
Predictive Maintenance in Semiconductor Systems: Insights from Machine Intelligence and Data-Driven Methods
Abstract: With the fast-paced development of semiconductor technology comes the need to focus on device reliability, or how long devices will function and the likelihood of devices having operational issues. Predicting failures and avoiding downtime with the implementation of timely, actionable, and data-driven maintenance strategies are essential to insure devices function sustainably within predetermined performance levels. The implementation of predictive maintenance within artificial intelligence and machine learning technologies will provide the …
Published in Journal of Semiconductor Devices and Circuits · Vol. 13, Issue 1, 2026 Read article
-
Multi-phase Flow Simulation Using Computational Fluid Dynamics
Abstract: Computational fluid dynamics (CFD)-based multi-phase flow simulation is a fast developing topic with broad applications in many scientific fields and industry. An extensive account of current developments, difficulties, and uses in multi-phase flow simulations is given in this review paper. Important modeling strategies, numerical methods, validation procedures, and new developments in CFD-based multi-phase flow analysis are covered. This paper is to contribute to the ongoing development and use of CFD …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 2, 2023 · pp. 28–34 Read article
-
Advancement in Image Classification: Media Player Control Using Hand Gestures
Abstract: We explore the development of picture categorization methods in this paper, with an emphasis on how they are used to manipulate media players with hand gestures. Our investigation focuses on the development of machine learning techniques, particularly on supporting vector machines (SVM) and convolutional neural networks (CNN). SVMs are used to identify and authenticate people from digital photos or video clips, but CNNs are great at face detection, which is …
Published in Recent Trends in Electronics Communication Systems · Vol. 11, Issue 2, 2024 · pp. 1–10 Read article
-
Lamivudine And Dolutegravir Simultaneous Dosage Forms Determined and Validated Using The RP-UPLC Method
Abstract: RP-UPLC has been used to produce a straightforward, precise, and accurate approach for the simultaneous estimation of dolutegravir and lamivudine in a pharmaceutical dose form. A HSS C18 column of 2.8 x 50 mm and featuring particles with a size of 1.6 μm was used to process the chromatogram. A mixture of 70:30 Buffer Na2HPO4 and methanol made up the mobile phase, which was pushed across the column at a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 5–13 Read article
-
Fruit Adulteration Detection Utilizing Machine Learning Methods
Abstract: A device utilizing Internet of Things (IoT) technology was developed for the identification of fruit adulteration through machine learning methods, specifically targeting formalin content assessment. The identification of the fruits based on their extracted traits has been accomplished using a variety of machine-learning techniques. The formalin concentration can be detected as an estimate of the generated voltage of any fruit via an Arduino Uno board 3 and a volatile compound …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 1, 2023 · pp. 32–45 Read article
-
Regression Analysis of Topological Indices and Physicochemical Properties of Polymer-Based Anticancer Drugs
Abstract: The research analyzed the quantitative correlation between topological indices and the physicochemical properties of selected anticancer compounds using regression analysis. Various topological descriptors—such as the First Zagreb Index, Second Zagreb Index, and Forgotten Index were calculated and regressed against key molecular features, including polar surface area, melting point, and molar refractivity. The regression analysis revealed linear correlations between these topological indices and the properties of anticancer drugs, with particularly strong …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 255–267 Read article
-
Identifying ABO Blood Group and Rh Status Using Dried Saliva Samples
Abstract: This article discusses the accuracy of dried saliva samples in establishing ABO and Rh blood types. Participants, likely screened for secretor status beforehand, submitted blood and saliva samples. Both samples were ABO blood typed (A, B, AB, or O) using standard methods such as gel card technology or hemagglutination assays. We used both saliva and blood to perform Rh typing. The findings revealed that saliva and blood typing for ABO …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 11–19 Read article
-
Optimization of Machining Parameters of EN-27 Material Using Wire Electric Discharge Machining (WEDM)
Abstract: The optimization of Wire Electrical Discharge Machining (WEDM) parameters for EN-27 alloy steel, a high-strength material widely utilized in mechanical and structural applications, is the subject of this study's methodical analysis. Due to its hardness and poor machinability by conventional methods, WEDM is preferred for achieving precise dimensional accuracy and surface integrity. The primary objective of this work is to enhance machining performance by identifying optimal process parameters influencing Material …
Published in Journal of Production Research & Management · Vol. 16, Issue 1, 2026 · pp. 32–36 Read article
-
Advancements in Ore Beneficiation Technologies: A Review of Modern Extraction Methods
Abstract: Ore beneficiation plays an essential role in the mining industry, as it facilitates the extraction of valuable minerals from their ores while ensuring maximum efficiency and minimal environmental impact. Beneficiation technologies have evolved significantly over time, leading to improvements in metal recovery rates and reduced waste generation. These advancements have enabled the mining industry to address increasing resource demands, with a particular focus on sustainability and cost-effectiveness. In this review, …
Published in International Journal of Minerals · Vol. 2, Issue 1, 2025 · pp. 36–40 Read article
-
Exploring the Impact of Artistic Expression on Children's Emotional Well-being: A Review
Abstract: Aim: The purpose of the review was to focus on how art therapy could improve children's mental health, particularly for those who are dealing with psychological or emotional difficulties. Children can communicate feelings and experiences that they might find difficult to express verbally via art therapy, a type of therapy that makes use of artistic expression. The review explores developmental ideas, including Malaguzzi's Reggio Emilia method, which encourages self-expression via …
Published in International Journal of Children · Vol. 2, Issue 1, 2025 · pp. 27–31 Read article
-
Performance Evaluation of Concrete with Binary and Ternary Blends of Fly Ash, Silica Fume, and Fiber Reinforcement
Abstract: This study evaluates the effect of ground granulated blast furnace slag (GGBS) as a partial replacement for cement on the mechanical properties of concrete, focusing on compressive and split tensile strength. Concrete mixes were prepared with GGBS replacement levels of 0%, 25%, and 50% and subjected to different curing methods, including water curing, steam curing, and conceal curing. These curing methods were selected to investigate their impact on hydration, strength …
Published in Journal of Construction Engineering, Technology & Management · Vol. 15, Issue 3, 2025 · pp. 40–45 Read article