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269 articles for “EPI”
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Anaphylaxis: Pathophysiology, Risk Factors, and Clinical Management
Abstract: Anaphylaxis is a syndrome characterized by broncho-constriction, vasodilatation, and hypovolemia, potentially fatal exposure to known or unknown antigens. It can be an immune-mediated (IgE & non-IgE) disease. Immunoglobulin G (IgG), complement related (C3a/C5a), bradykinin, leukotrienes, prostaglandin E2, and ligands of certain G-protein coupled receptors (GPCR) can directly activate mast cells, basophils, eosinophils, neutrophils, endothelial cells and smooth muscles. Serum tryptase level during episodes of anaphylaxis, skin test, and basophil activation …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 1–11 Read article
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Demodex spp. (Acari: Demodicidae) Infestation in Humans: Diagnostic Clues and Therapeutic Approaches to Primary and Secondary Demodicosis.
Abstract: Demodicosis represents an inflammatory dermatosis and adnexal disorder arising from pathologic overgrowth of Demodex mites, primarily Demodex folliculorum and Demodex brevis, which are ubiquitous human ectoparasites residing in pilosebaceous units and eyelid margins. Once regarded as benign commensals, these mites are now recognized as primary drivers or key cofactors in diverse clinical phenotypes, including papulopustular eruptions, pityriasis folliculorum, rosacea-like disorders, blepharitis, meibomian gland dysfunction, and exacerbations of comorbid dermatoses such …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 12–20 Read article
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Time Series Forecasting Based on PyAF and fbProphet
Abstract: Time series forecasting is the technique of predicting future events using previous data. Time series data includes information that is collected and recorded at regular intervals, such as daily stock prices, monthly sales figures, or hourly temperature readings. The purpose of time series forecasting is to use previous data to create accurate forecasts about the future values of a given variable. This can be beneficial for a range of applications, …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 1, 2023 · pp. 32–36 Read article
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Understanding Tennis Elbow: Causes, Symptoms, and Available Treatments
Abstract: Tennis Elbow, clinically termed lateral epicondylitis, stands as a prevalent musculoskeletal ailment affecting the outer part of the elbow. Despite its name, this condition isn't exclusive to tennis players; it often arises due to repetitive stress or overuse of the forearm muscles and tendons, leading to micro-tears and inflammation at the elbow's lateral epicondyle. The abstract focuses on elucidating the multifaceted aspects of Tennis Elbow, exploring its causes, symptoms, and …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 1–5 Read article
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A Comprehensive Review On Panic Disorders
Abstract: Panic disorder is a prevalent mental health condition characterized by sudden, recurring episodes of intense fear accompanied by physical symptoms. It is twice as likely to affect women and may have a genetic predisposition. This disorder stems from an exaggerated response of the body's survival mechanisms and hormones, impacting manifestations like agoraphobia. Additionally, it is associated with significant psychiatric comorbidity and impaired functioning in various roles. Recent research has delved …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 53–59 Read article
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Real Time Characterization of BA.2.86 and Its Variant (JN.1) in Senegal Using Midnight Protocol
Abstract: During the week ending August 13th, 2023, the most prevalent variant of interest (VOI), uploaded to GISAID, was the BA.2.86 variant. This SARS-CoV-2 Omicron lineage was described as the first phylogenetically distinct from the currently circulating SARS-CoV-2 Omicron XBB lineages, including EG.5.1 and HK.3. Compared to the XBB and BA.2 lineages, the BA.2.86 possesses more than 30 mutations in the Spike (S) protein, suggesting a significant potential for immune evasion. …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 16–21 Read article
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A Review on Evolution of Medicine After and During Corona
Abstract: As of the beginning of 2023, 6.7 million people had perished from COVID-19, according to the World Health Organization. However, there have also been some positive developments, such as the notable decline in influenza-related deaths in the first year of the pandemic as a result of masking and social isolation, as well as the quick adoption of vaccines utilizing cutting-edge technologies like mRNA vaccines, which hold out great promise for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 1–9 Read article
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Ecology of Leaf Adaptations in Azardirachta indica A. Juss at Desert Environment
Abstract: Azardirachta indica A. Juss is a medicinally important plant belonging to the family Meliaceae. It is widely used during COVID 19 for its anti-inflammatory and antiviral effects for COVID 19 prophylaxis. Although the plant is native to India, but is very much naturalized in tropical and subtropical countries. It is one of the commonly used plant for shelterbelt and wind break system along roadsides also. The present investigation was done …
Published in Research & Reviews : Journal of Ecology · Vol. 13, Issue 1, 2024 · pp. 7–11 Read article
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Necrotizing Enterocolitis (NEC): A Devastating Neonatal Gastrointestinal Disorder
Abstract: Necrotizing enterocolitis (NEC) represents a formidable challenge in neonatal medicine, particularly afflicting premature infants with its characteristic features of severe intestinal inflammation and necrosis. Despite advancements in neonatal care, NEC continues to exact a heavy toll, standing as a prominent cause of morbidity and mortality in this vulnerable population. Its multifaceted etiology, encompassing prematurity, enteral feeding practices, alterations in microbial colonization, and episodes of intestinal ischemia, underscores the complexity of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 78–83 Read article
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Clinical Profiles of Patients Presenting with Hypoglycemia in Emergency Department of Bir Hospital
Abstract: Hypoglycemia stands as a primary reason for visits to the Emergency Department (ED), ranking high among the most frequent and easily avoidable hormonal emergencies. The aim of this research is to investigate the occurrence of hypoglycemia and identify its underlying causes. As the number of diabetes cases rises, along with different methods of tightly managing blood sugar levels, the likelihood of hypoglycemia also increases. Given that extended periods of hypoglycemia …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 · pp. 19–39 Read article
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Unravelling the Environment, Aroma, and Molecular Effects on Mood Fluctuations: A Review
Abstract: The ebb and flow of human emotions encompass a complex interplay of molecular processes governing mood fluctuations. This comprehensive review navigates the intricate realm of neurotransmitters, neuroplasticity, hormonal influences, genetics, and inflammation to unravel the molecular tapestry that shapes our emotional states. Foundational to mood regulation are neurotransmitters – serotonin, dopamine, and norepinephrine – orchestrating delicate balances within neural circuits. Recent molecular neuroscience elucidates their receptor pathways and signaling cascades, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 14–20 Read article
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Jabuticaba Skin Flour AsA Functional Food Ingredient: Phenolic Profile, Antioxidant Potential and Functional Technological Properties
Abstract: Brazilian-native fruit, jabuticaba, is a member of the Myrtaceae family that is typically consumed naturally. The jabuticaba skin flour (JSF) is rich in phenolic compounds, the most active antioxidants present in plants, being able to stop oxidative damage and reduce the risk of oxidative stress linked to different degenerative diseases, thus become interesting to the consumer. Despite all this antioxidant potential, little is known about their characterization and about the …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 3, 2024 · pp. 01–08 Read article
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Improvement of Convergence Speed of Q-learning based Path Planning Algorithm
Abstract: Path planning is fundamental and important task of mobile robot. There are many attempts to adopt reinforcement learning (RL) in mobile robot path planning. RL based path planning is effective in path planning of intelligent mobile robot, especially in unknown environment because it doesn’t require environmental information and finds optimal path through trial-and-error process. Q-learning is one of RL algorithm widely used in path planning of mobile robots. The main …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 2, Issue 2, 2024 · pp. 19–28 Read article
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History and Historiography of Origin and Development of Maiduguri Borno State, Nigeria
Abstract: This study discussed the history of Maiduguri as pertain to its growth, economic, educational development and its administrative structure. Materials for the work were mainly retrieved from the library where extant work attributed to some to some scholarly sources were used. The internet was also a useful source as some scholarly papers placed there helped a great deal. In essence, this library research that relied heavily on previous research on …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 1, 2025 · pp. 5–13 Read article
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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Role of Food Supplements in Premalignant Lesions: A Literature Review
Abstract: Premalignant lesions of the oral cavity are histopathological alterations in the oral epithelium linked to a higher likelihood of malignant transformation. These lesions frequently present as leukoplakia (white patches), erythroplakia (red patches), oral lichen planus, and oral submucous fibrosis. Oral cancer, categorized among head and neck malignancies, is considered the sixth most common cancer globally. While tobacco and alcohol consumption remain the primary etiological factors, increasing evidence underscores the significant …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 17–26 Read article
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The Evolution and Impact of Numbers: From Ancient Tallies to Quantum Computing: Review Article on Numbers
Abstract: Numbers are among the most fundamental constructs in human civilization, serving as the backbone of mathematics, science, technology, and virtually every aspect of daily life. They represent not only quantities and measures but also relationships, structures, and patterns that underpin the fabric of human understanding. From the earliest tallies etched on bones by prehistoric humans to the sophisticated numerical systems embedded in today’s artificial intelligence and quantum computing, the evolution …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 3, 2025 · pp. 15–19 Read article
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Climate Change and Air Pollution Dynamics: Synergistic Effects and Mitigation Strategies
Abstract: Climate change and air pollution are deeply interlinked environmental problems that jointly exacerbate human health, ecosystem integrity, and economic well‑being. As global temperatures rise, shifts in meteorological conditions—such as increased heat, altered precipitation, and more frequent extreme weather events—modify pollutant generation, dispersion, chemical transformation, and removal processes. Meanwhile, many sources of air pollution are also sources of greenhouse gases (GHGs), giving rise to potential co‑benefits or trade‑offs when formulating mitigation …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 2, 2025 · pp. 38–42 Read article
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Unlocking Novel Drug Targets and Therapeutic Advancements Against RNA Viruses: Insights from HMPV and SARS-CoV-2
Abstract: Re-emerging RNA viruses pose a significant epidemiological welfare threat due to their high mutation rates, potential for zoonotic transmission, and capacity to cause widespread outbreaks such as Human Metapneumovirus (HMPV), Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Influenza, etc. The rapid evolution and re-emergence of these viruses necessitate the development of novel drug targets and therapeutic strategies to combat existing and future outbreaks. This study focuses on structural as well …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 54–86 Read article
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From Outbreak to Output: Uganda’s COVID-19 Research Trajectory Through a Scientometric Lens
Abstract: The COVID-19 pandemic sparked an extraordinary global expansion in scientific research, with notable and growing contributions from low- and middle-income countries, including Uganda. This study presents a comprehensive scientometric analysis of COVID-19 related research output from Uganda, aiming to examine publication trends, authorship patterns, collaboration networks, source impact, and thematic focus. Bibliographic data were retrieved from the PubMed database using an advanced search strategy: “(COVID-19) OR (SARS-CoV-2)) AND (Uganda)” for …
Published in Journal of Advancements in Library Sciences · Vol. 13, Issue 1, 2026 · pp. 48–60 Read article