Search
1979 articles for “additives” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
-
Innovations in Oral Drug Delivery: Challenges and Opportunities
Abstract: The advancement of novel drug manufacturing technologies offers immense opportunities for innovation but brings regulatory complexities that must be addressed to ensure successful implementation. Early and frequent collaboration with the FDA is fundamental for overcoming these challenges. The establishment of the FDA’s Emerging Technology Team has been pivotal in fostering open dialogue, brainstorming, and feedback between regulators and innovators, reducing the likelihood of unexpected setbacks that could jeopardize projects. Mechanisms …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 31–43 Read article
-
Pharmacokinetic and Pharmacodynamic Studies of Black Seed Derived Compound
Abstract: Black seed (Nigella sativa) has been celebrated for centuries for its remarkable therapeutic properties. Among its bioactive compounds, thymoquinone (TQ) has gained significant attention in pharmacological research due to its diverse health benefits. This review delves into the pharmacokinetic (PK) and pharmacodynamic (PD) properties of black seed compounds, with a particular emphasis on TQ, the most extensively studied component. The PK of TQ includes the parameters of absorption, distribution, metabolism, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 36–43 Read article
-
Herbal Medicines and Complementary Therapies: Their Role, Types and Applications
Abstract: Medicinal plants are used in herbal medicine to treat and prevent illnesses. This includes the use of standardized and titrated botanical extracts in addition to common and traditional medicines from different cultures. The safety of a treatment may be suggested by its long history and deep cultural roots in traditional medical systems, but this does not always imply that it is effective. This is especially important in herbal medicine, since …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 40–53 Read article
-
A Literature Review on Extrusion/Spheronisation-A Pelletization Technology
Abstract: Extrusion-spheronization is a leading pelletization technology, widely favored for its economic and commercial viability. It is a cost-effective method suitable for large-scale production, making it the most efficient approach for oral drug delivery. This process provides multiple benefits, such as improved flow characteristics, lower friability, a narrow particle size range, easier coating, consistent packing, reduced likelihood of dose dumping, and more predictable gastric emptying. Pellets usually measure between 0.5 and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 61–71 Read article
-
Enhancing Building Energy Efficiency Through IoT Integration
Abstract: Building management systems featuring Internet of Things (IoT) technology provide a revolutionary way of maximizing user comfort and improve the use of energy. This study presents a comprehensive analysis of various components within an IoT subsystem utilized in building management, including Smart IoT Gateways, temperature and humidity sensors, lightweight database systems such as Tiny DB, and cloud communication platforms like Twilio. Each component plays a vital role in facilitating real- …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 2, Issue 2, 2024 · pp. 15–23 Read article
-
Effect of Carbon Nanotube on Mechanical Properties of Jute Fibre Reinforced Polyester Composite
Abstract: The current study studies how carbon nanotubes affect the mechanical characteristics of polyester composites reinforced with jute fiber, both treated and unprocessed. Alkali was used to cure jute textiles. Composites with treated and untreated jute fibre with 5%, 10% and 15% jute fibre loading with and without carbon nanotube were prepared using hand lay-up process. Carbon nanotubes varied from 0.2%, 0.4% and 0.6%. Tensile, flexural, and strength of impact all …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
-
Artificial Intelligence for Improved Healthcare: A Case Study and Applications
Abstract: Artificial intelligence (AI) in healthcare ushers in a revolutionary period of innovation, but it also brings with it significant ethical dilemmas. This paper explores the complex relationship between AI and healthcare, emphasizing both its useful applications and the moral conundrums that arise. Ethical issues span a wide range, including patient privacy, transparency, accountability, and the unintentional reinforcement of biases in AI algorithms. Privacy concerns take center stage as healthcare providers …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 1–12 Read article
-
AI: Revolutionizing Pharmacy Practice and Enhancing Patient Care and Safety
Abstract: The use of artificial intelligence (AI) in pharmacy is transforming medication management, improving patient care, and boosting safety. By leveraging cutting-edge technologies, such as machine learning, natural language processing, and predictive analytics, AI enables pharmacists to develop personalized treatment plans and anticipate possible adverse drug reactions. AI-driven systems enhance operational efficiency by streamlining inventory management, prescription processing, and administrative duties, allowing pharmacists to devote more time to patient care. Additionally, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 13–20 Read article
-
Metro Systems' Role in Reducing CO2 Emissions in Urban Transport
Abstract: To better understand the impact of metro systems on reducing CO2 emissions in urban transport, a detailed analysis is required. This analysis should evaluate both the direct and broader effects of metro networks on the overall urban transportation system. It is crucial to quantify the actual contribution of metro systems in cutting CO2 emissions by considering the entire transport network. The evaluation should include not only the emissions generated by …
Published in Trends in Transport Engineering and Applications · Vol. 11, Issue 3, 2024 · pp. 19–22 Read article
-
Policies on Emissions of Greenhouse Gases and Other Atmospheric Pollutants by the Railway Transport Sector
Abstract: This work seeks to identify, understand, and analyze laws and regulations from different European Union countries that focus on emissions of greenhouse gases and other atmospheric pollutants by the rail transport sector, both freight and passenger. The search to identify legislation was carried out through the use of artificial intelligence and, subsequently, an active search for documents relevant to the topic was carried out. During the research, data on the …
Published in Trends in Transport Engineering and Applications · Vol. 11, Issue 3, 2024 · pp. 14–18 Read article
-
Advances in Total Knee Replacement: A Systematic Review of Clinical Outcomes and Complications
Abstract: Total Knee Replacement (TKR) is a widely used surgical intervention for patients with knee osteoarthritis and other degenerative knee disorders, offering significant improvements in pain relief, functional restoration, and quality of life. This systematic review synthesizes data from multiple clinical studies to evaluate the outcomes and complications associated with TKR. To find applicable research published in the last ten years, a thorough search of electronic databases was performed. Randomised controlled …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 41–56 Read article
-
Correlation Analysis of Gastrocnemius Tightness and Heel Pain Severity: A Study on Plantar Fasciitis
Abstract: Background: Plantar fasciitis, a common source of heel pain, is frequently linked to tightness in the gastrocnemius (GCN) muscle. This study seeks to examine the relationship between GCN tightness and the severity of heel pain in plantar fasciitis patients over time, investigating the potential role of muscle flexibility in alleviating pain. Methods: A prospective cohort study was conducted with 74 patients aged 25–65 diagnosed with P. fasciitis at Santosh Hospital, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 57–64 Read article
-
Mathematical Models of Agricultural Cycles in Tribal Astronomy
Abstract: This paper delves into the intricate connection between traditional tribal agricultural practices and astronomical observations, showcasing how indigenous communities have historically relied on celestial movements to guide essential farming activities. By observing the phases of the moon, solar cycles, and the positions of star constellations, tribes have developed precise methods for determining the optimal timing for planting, harvesting, and seasonal planning. These astronomical practices are deeply embedded in their cultural …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 3, 2024 Read article
-
Exploration of Partial Order Structures in Menger Spaces Properties Characterizations and Applications
Abstract: Partial order structures play a crucial role in understanding the intricate relationships within mathematical spaces. In this paper, we delve into the realm of Menger spaces and investigate their properties through the lens of partial orders. Menger spaces, a generalization of metric spaces, possess unique characteristics that can be further elucidated by considering partial order structures. Through rigorous analysis, we explore various properties of partial order Menger spaces, including topological …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 11, Issue 3, 2024 · pp. 17–22 Read article
-
Comprehensive study of Entanglement Entropy in Quantum Field Theory: Analysis of Conformal Field Theory to Massive Field Extensions and Holographic Entanglement
Abstract: This paper provides an in-depth analysis of entanglement entropy (EE) in quantum field theory (QFT), with a particular focus on its computation using the replica trick and its applications to both conformal and non-conformal systems. Beginning with an introduction to the basics of QFT, the study explains how entanglement entropy quantifies the quantum correlations between subsystems in a pure state, represented by the von Neumann entropy of the reduced density …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 3, 2024 · pp. 33–58 Read article
-
Utilize Nature’s Power: Nutraceuticals in the Fight Against Dengue
Abstract: As dengue fever continues to surge across tropical and subtropical regions, the exploration of novel therapeutic approaches is crucial. Nutraceuticals, natural bioactive compounds derived from food sources, are emerging as promising adjuncts in the fight against this viral disease. Unlike conventional treatments that primarily target symptoms, nutraceuticals offer a complementary strategy by enhancing the body’s immune defense and addressing key complications. This review highlights the diverse potential of nature’s remedies, …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 19–27 Read article
-
Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
-
Enhancing Engine Efficiency and Reducing Emissions: A Comprehensive Review of Air Calorimeter Technology
Abstract: The article talks about the idea behind this project to pre-heat the intake air that passes through the carburettor to increase a petrol engine's fuel efficiency. The vaporization of petrol in the carburettor is influenced by the humidity of the surrounding air. Therefore, vaporization can be facilitated, and full combustion can be accomplished by preheating the carburettor's incoming air for a significant amount of time. Additionally, by lowering the amount …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 8–13 Read article
-
Smart Safety: Evaluating Inviguard as an Innovative Wearable for Head Protection
Abstract: This study details INVIGUARD, an innovative head protection wearable device designed to prevent falls and accidental collisions for the special people. The device is neck-worn and utilizes a unique structure in the form of a honeycomb which when a threat is recognized will expand in volume to form a protective shield around the head whilst in normal usage is small in size; when the danger is no longer perceived. Such …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 1, 2025 · pp. 15–26 Read article
-
A Practical Approach for Privacy Preserving in Cloud Computing Using Fully Homomorphic Encryption Scheme BFV and CKKS
Abstract: Cloud computing is a new type of computing architecture whereby data may be accessed over the Internet along with other services linked to its scalable data centers in the cloud. The risk associated with computing is increased since it provides essential services that are typically provided to any third party, making it more difficult to enable data security, privacy, confidentiality, integrity, and authentication. To reduce security risks, most users choose …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article