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239 articles for “targeted delivery”
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A Review on Novel Emulsification Technique: A Nanoemulsion
Abstract: Kinetically stable and isotropic system of submicron size range is the nanoemulsion. In this system two immiscible liquids are mixed together to form a single-phase system with the identical concentration and ratio of surfactant and cosurfactant. Nanoemulsion droplet sizes fall typically in the range of 20- 200 nm. Some literature suggest this range below 100 nm with shows narrow size distribution. In this review, major focus is given on the …
Published in Trends in Drug Delivery · Vol. 3, Issue 2, 2016 · pp. 25–34 Read article
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Current Trends in Crossing the Blood–Brain Barrier: A Review
Abstract: The blood-brain barrier (BBB) is a protective barrier that protects the central nervous system (CNS) from toxins and pathogens in the blood. However, the existence of BBB challenges therapy for CNS diseases and disorders as most pharmaceuticals (drugs) are restricted to enter brain. The review article focuses on the approaches involved to cross BBB with various advanced technology such as nanoparticles, intraventricular injection, chemical modifications, virus mediated distribution, exosome mediated …
Published in Trends in Drug Delivery · Vol. 10, Issue 2, 2023 · pp. 25–38 Read article
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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Lipid Drug Conjugates: A Novel Approach for Drug Delivery A Systematic Review
Abstract: The lipid drug conjugates (LDCS) a novel lipid based nanoparticles which has been extensively employed for the delivery and targeting of drugs. These have been exploited for many features in the field of pharmaceutical technology. The lipid drug conjugates have a 33% drug loading capacity more than the solid lipid nanoparticles (SLNs). The lipid drug conjugates have the potential to act as a delivery system for hydrophilic and lipophilic drugs, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 3, Issue 3, 2012 · pp. 1–8 Read article
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Nasal Medication Conveyance Framework: An Approach for Brain Delivery from Essential to Cutting Edge
Abstract: For the past few years, nasal drug delivery has provided attractive niche to the formulation scientists. It is the first choice as targeted drug delivery when one requires it for brain targeting. In addition, absorption of drug at the olfactory region of the nose provides a potential for a pharmaceutical compound to be available to the central nervous system. The nasal delivery of vaccines is another very attractive application in …
Published in Research and Reviews: A Journal of Medicine · Vol. 6, Issue 1, 2016 · pp. 14–27 Read article
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A Review on Nanosponges Drug Delivery System
Abstract: The main issue that the researchers are dealing with is targeted medication delivery to locations. Crosslinking polymers produce nanosponges, which are three-dimensional drug delivery systems at the nanoscale. They have the benefit of having a large capacity to carry different-sized medications. There are numerous sizes and shapes for nanosponges. Compared to alternative delivery methods, nanosponges are preferable because they may offer a regulated medication release pattern with targeted Medication administration. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 68–76 Read article
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Anatomization On Controlled Drug Delivery System
Abstract: Modern target-perception technologies have led to the development of successful controlled drug delivery systems. The process of administering a medication so that it is clinically effective in either people or animals is known as drug supply. Several of the earliest controlled-release systems aimed to achieve a delivery profile that would result in a high drug level in the blood for an extended length of time. When using conventional medication delivery …
Published in Trends in Drug Delivery · Vol. 10, Issue 3, 2023 · pp. 24–32 Read article
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Use of CRISPR/Cas9 in Delivery System with Nanotechnology Concept
Abstract: In this emerging era of science and technology development, the use of drug delivery concept has made possible to cure several health problems, but for certain genetic diseases like Sickle cell anemia, chronic diseases like cancers, Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/CRISPR associated system (Cas) gene-editing system is here as a promising tool to cure them by doing certain gene manipulation in specific gene area causing the disease. However, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 12, Issue 2, 2022 · pp. 16–23 Read article
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Liposomes Innovative Role as a Drug Delivery System: A Detailed Analysis
Abstract: The first nanomedicine to be approved for use in clinical settings was liposomes. These are the spherical vesicles with a bilayer of phospholipids enclosing a middle empty aqueous region. Because of their extraordinary potential to stop medication deterioration and lessen unwanted effects, liposomes are being utilized more and more for targeted drug distribution. For targeted drug delivery, the pharmaceuticals can be integrated into the liposomes' aqueous space or phospholipid bilayer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 25–32 Read article
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Techniques for Characterization of Anticancer Drug Loaded Polymeric Nanoparticles: A Review
Abstract: Normal 0 false false false EN-US X-NONE X-NONE Polymeric nanoparticles have been used for targeted drug delivery against different diseases during last decades. Particularly in cancer, targeted polymeric nanoparticles can be used to deliver anticancer drugs to cancer cells with reduced cytotoxicity and greater efficacy. Various natural polymers like chitosan, albumin, gelatin and synthetic such as Polylactides (PLA), Poly (Lactide co-Glycolides) (PLGA) have been researched as carrier of anticancer drugs. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 5, Issue 2, 2015 · pp. 32–43 Read article
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Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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A Review on Polymeric Nano-particles
Abstract: Conventional drugs have major demerits of poor biodistribution, decreased effectiveness and less targeting effect. Strategies like controlling drug delivery can potentially overcome these limitations by transporting drug to the place of action. The polymeric nanoparticles (PNPs) are prepared from biocompatible and biodegradable polymers in size between 1–1000 nm. PNPs are suitable carriers for drug delivery to specific target site; such an advantage improves the drug safety and lowers toxicity. In …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 1–7 Read article
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4D Printing in Drug Delivery: Application of Shape- Morphing Materials in Controlled Drug Release
Abstract: Four-dimensional printing technology has transformed the pharmaceutical landscape, offering unprecedented opportunities for innovation in drug development and delivery. This emerging technology enables the creation of complex geometries and customized structures, facilitating the design of personalized medications tailored to individual patient needs. Personalized dosing and drug release profiles, customized pill shapes and sizes for improved swallowability. Enhanced drug solubility and bioavailability, rapid prototyping and testing of pharmaceutical products. Development of complex …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 08–16 Read article
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A Review of Nanotechnology Application in Pharmaceutical and Health Care
Abstract: Nano drug and nano delivery systems are a fairly new but fleetly developing wisdom where accoutrements in the nanoscale range are employed to serve as means of individual tools or to deliver remedial agents to specific targeted spots in a controlled manner. Nanotechnology provides numerous advantages in treating chronic diseases by enabling precise, site-specific, and targeted drug delivery. Recently, there have been several remarkable applications of nanomedicine, including chemotherapeutic agents, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 07–17 Read article
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Nanomedicine in Combination with Artificial Intelligence (AI): Transforming Cancer Treatment
Abstract: The convergence of nanomedicine and artificial intelligence (AI) holds transformative potential for advancing cancer treatment, particularly in liver cancer. Nanomedicine enables the development of targeted drug delivery systems, enhanced imaging modalities, and precise therapeutic interventions, while AI facilitates data-driven decision-making, personalized treatment plans, and predictive analytics. This synergistic approach can significantly improve the diagnosis, treatment, and monitoring of liver cancer by optimizing the use of nanoparticle-based therapies. AI-powered algorithms can …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 27–30 Read article
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Initiatives of Nanotechnology to Combat Diabetes Mellitus
Abstract: Diabetes is the single most important metabolic disease which can affect approximately every organ system in the body. It has been projected that 300 million individuals would be affected with diabetes by the year 2025. In India, it is estimated that presently 19.4 million individuals are affected by this deadly disease, which is likely to go up to 57.2 million by the year 2025. It is imperative that effective monitoring …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 3, Issue 2, 2013 · pp. 38–47 Read article
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Preparation and Characterization of Eucalyptus Oil Nasal Microemulsion System Using Polysorbate 80
Abstract: The nasal route is considered as an alternative route of drug administration for the delivery and targeting drugs safely. The nasal absorption of the drug protects from the degradation of the drug in the gastrointestinal environment and liver metabolism. Eucalyptus oil is an essential oil frequently used for the treatment of common cold and nasal congestion. The microemulsion system of eucalyptus oil will provide effective delivery of the oil to …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
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Recent Advances in Nanobiotechnology: Applications and Future Perspectives
Abstract: Nanobiotechnology is a rapidly growing field that combines the principles of nanotechnology with biology, medicine, and biotechnology. This review article provides an overview of recent advances in nanobiotechnology and their applications in various fields, including drug delivery, imaging, biosensors, tissue engineering, and nanomedicine. The article also discusses the challenges and future prospects of nanobiotechnology. This review article provides an overview of recent advances in nanobiotechnology and their applications in various …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 24, Issue 3, 2022 · pp. 43–47 Read article