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134 articles for “data profiling”
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In Vivo Biocompatibility and Interfacial Stability of Thermoplastic Polyurethanes and Nanofilled Resin Composites: A Bioanalytical Study of Polymer-Host Interactions Under Dynamic Loading
Abstract: The widespread application of thermoplastic polyurethanes (TPU) and nanofilled resin composites in biomedical devices requires rigorous assessment of their biocompatibility under mechanical stress. While nanofilled composites utilize filler particles (<100 nm) to enhance surface properties and wear resistance, the biological response to these materials in a hydrolytic, enzymatic environment remains a critical area of investigation. Objective: To analyze the in vivo bio-molecular response at the interface of TPU aligners and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1112–1119 Read article
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Multi-Sensor System for Underwater Pothole Detection to Enhance Road Safety During Monsoon Seasons
Abstract: Monsoon seasons across India and similar tropical regions severely compromise road safety by causing water accumulation that conceals dangerous potholes beneath stagnant pools, leading to frequent vehicle damage, tire punctures, and fatal accidents. Traditional detection methods relying on smartphone accelerometers, ultrasonic sensors, or machine vision fail under flooded conditions due to acoustic signal reflection at water surfaces and optical distortions from glare and turbidity. This research proposes an innovative multi-sensor …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 4, Issue 1, 2026 · pp. 25–32 Read article
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Performance Forecasting in Solo Sports: Leveraging Psychometrics, Economic Analysis, and Cultural Insights for Predictive Excellence
Abstract: The science of performance forecasting in solo sports has transcended traditional metrics, embracing a multidisciplinary approach. This paper explores the integration of psychometrics, economic analysis, and cultural insights to predict athletic success. By leveraging psychological profiling, economic factors, and cultural dynamics, this study aims to establish a comprehensive model for forecasting athlete performance with heightened accuracy. In the realm of solo sports, where individual prowess dictates success, traditional performance forecasting …
Published in Recent Trends in Sports · Vol. 1, Issue 1, 2024 · pp. 35–44 Read article
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GLP-1 Receptor Agonists: A Dual Therapeutic Strategy for the Management of Type 2 Diabetes Mellitus and Obesity
Abstract: For the treatment of obesity and type 2 diabetes mellitus (T2DM), glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become a revolutionary class of pharmaceutical drugs. These drugs were first created as glucose-lowering treatments, but they have now shown other advantages, such as notable weight loss, better cardiovascular results, and general metabolic control. The objective of this narrative review is to assess the pharmacological mechanisms, clinical efficacy, safety profile, and therapeutic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 69–75 Read article
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Design and Evaluation of Extended-Release Tablet Compositions Containing Oxaprozin: Integrating Concepts from Bioinformatics
Abstract: The procured sample of Oxaprozin was tested for its identification. The manufacturer also was confirmed of quality and purity of sample. The sustained release tablets of Oxaprozin were prepared by wet granulation method, They were evaluated for weight variation, drug content, friability, hardness, and thickness for all batches (T-1 – T-10). The release of Oxaprozin from sustained release tablet of various formulations varied according to the ratio and degree of …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 39–45 Read article
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Design and Evaluation of Extended-Release Tablet Compositions Containing Oxaprozin: Integrating Concepts from Bioinformatics
Abstract: The procured sample of Oxaprozin was tested for its identification. The manufacturer also was confirmed of quality and purity of sample. The sustained release tablets of Oxaprozin were prepared by wet granulation method, They were evaluated for weight variation, drug content, friability, hardness, and thickness for all batches (T-1 – T-10). The release of Oxaprozin from sustained release tablet of various formulations varied according to the ratio and degree of …
Published in Research and Reviews: A Journal of Toxicology · Vol. 11, Issue 1, 2024 · pp. 39–45 Read article
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Phytotherapeutic Potential of Melaleuca: An Integrative Review of Phytochemistry and Antimicrobial, Antifungal, Antioxidant, and Antiviral Mechanisms
Abstract: Melaleuca alternifolia and other species of the Melaleuca genus stand out for the broad spectrum of pharmacological properties attributed to their bioactive compounds, such as monoterpenes, sesquiterpenes, flavonoids, and polyphenols. This study aimed to critically review and analyze scientific evidence produced between 2005 and 2025 regarding the antimicrobial, antifungal, antioxidant, and antiviral activities of Melaleuca, correlating its phytochemistry with molecular mechanisms of action. For this purpose, an integrative literature review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Efficient Malware Detection in Cybersecurity: Leveraging Advanced Data Structures for Enhanced Threat Identification
Abstract: The cybersecurity landscape is constantly changing with more advanced malware creating major challenges for detection systems. To address these challenges effectively, advanced data structures have become essential in optimizing how data is managed, processed, and analyzed for malware detection. This review paper delves into the role of several cutting-edge data structures—bloom filters, tries, hash tables, graphs, decision trees, and suffix trees—in enhancing the efficiency and accuracy of malware detection mechanisms. …
Published in International Journal of Data Structure Studies · Vol. 2, Issue 2, 2024 · pp. 32–40 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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IoT-Based Battery Health Monitoring for Electric Vehicles Using Machine Learning
Abstract: With increasing utilization of the Electric Vehicles (EV)s in global scale, battery health management becomes a critical factor which has great impact on vehicle performance, safety and longevity. Battery materials, such as NMC LFP lithium-ion batteries and lithium-ion batteries, degrade over time from charging behaviour, heat stress, discharging voltage profiles and environmental limits. Conventional BMS only offer threshold based health diagnostics and cannot perform accurate degradation prediction. This work presents …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 4, Issue 1, 2026 Read article
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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Advancing Asthma Management: The Synergy of Systems Biology, Artificial Intelligence, and Next-Generation Therapeutics
Abstract: Asthma is an inflammatory disorder of the respiratory tract that is chronic and heterogeneous in nature and has various effects on millions of people. Being a chronic inflammatory disease, asthma remains incurable and the major conventional treatments offer limited success due to the mask nature of its pathophysiology. Systems biology/(AI), and next-generation has greatly enhanced knowledge and the management of asthma. The approaches based on gene, transcript, protein, and metabolite …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–12 Read article
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Smart AI-Enhanced Tool for Comprehensive Mock Interview Practice
Abstract: Job seekers often struggle with interview preparation due to a lack of structured practice, real-time feedback, and a realistic interview environment. Traditional methods, such as self-practice or mock interviews with peers, may not provide an accurate assessment of a candidate’s readiness for real-world job interviews. This research work introduces an AI-based mock interview tool designed to enhance skills based on a user's job profile. The platform is built using React …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 12, Issue 2, 2025 · pp. 20–25 Read article
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An Empirical Analysis of Bluetooth Low Energy Reliability Challenges for Offline Messaging Applications
Abstract: In today's hyper-connected world, modern communication relies heavily on centralised internet infrastructure, making robust offline messaging solutions increasingly essential. A crucial vulnerability is revealed by network failures, natural disasters, and distant region deployments: communication breaks down when internet connectivity does. Due to its low power consumption and almost ubiquitous availability in contemporary smartphones, Bluetooth Low Energy (BLE) has become a promising candidate for offline, device-to-device communications. This study presents an …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 13, Issue 2, 2026 Read article
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Machine-Learning-Assisted Development of Polymer-Biochar Composite Adsorbents for the Removal of Heavy Metals from Gomti River Water
Abstract: Rapid urbanization, industrial discharge, and agricultural runoff pose a significant threat to freshwater sustainability and public health. Within these ecosystems, polymer pollutants—such as microplastics, nanoplastics, synthetic fibres, and additive residues—have emerged as persistent vectors capable of adsorbing and transporting toxic heavy metals. Because these polymeric contaminants dynamically interact with conventional aquatic parameters to alter pollutant mobility and ecological risk profiles, there is an urgent need to transition from passive environmental …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 72–95 Read article
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Computational Investigation of Withania somnifera Compounds Targeting S. pombe SMN YG-Dimer in Spinal Muscular Atrophy: Insights from Molecular Docking Analysis
Abstract: Objectives: The primary objective of this study is to determine the potential of phytochemical constituents of Withania somnifera in treating spinal muscular atrophy, an autosomal recessive genetic neurodegenerative disorder, through computational techniques. To investigate the binding affinity of phytocompound to the target protein S. pombe SMN YG-Dimer through molecular docking. Besides, evaluating the pharmacological attributes of phytochemical constituents to assess their ability as an ideal prospect for developing therapeutic medication. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 39–52 Read article
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Mid-Year Epidemiological Profile of COVID-19 Posi ve Cases in Rajasthan, India
Abstract: Background: COVID-19, caused by SARS-CoV-2, has posed persistent public health challenges globally since its emergence in late 2019. India, through enhanced surveillance and vaccina on, has seen a progressive decline in case burden. Despite improvements, localized surges and emerging variants necessitate con nuous monitoring. Rajasthan, with its urban-rural health dispari es, experienced a modest resurgence of cases in early 2025, raising concerns about exis ng immunity gaps and health system …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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SpecForesight: A Predictive Analytics Pipeline for Laptop Price Forecasting
Abstract: This paper frames laptop pricing as a supervised predictive analytics problem, transforming product specifications into feature-rich signals to forecast price with calibrated regression models and operational guardrails against drift. A structured pipeline ingests tabular listings, performs data cleaning, and engineers domain-informed features (e.g., central processing unit (CPU) family and clocks, graphics processing unit (GPU) tiering, memory/storage density, display, and touch capabilities), followed by encoding and normalization to optimize model learnability. …
Published in Journal of Computer Technology & Applications · Vol. 17, Issue 1, 2026 · pp. 61–71 Read article
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Psychological Profile of Patients Undergoing Hemodialysis and Its Association with Physiological Parameters
Abstract: Background: End-stage renal disease (ESRD) is a chronic, progressive condition requiring maintenance hemodialysis, which imposes substantial physiological, psychological, and social burdens on patients. While physiological indicators are routinely monitored during treatment, the influence of psychological factors on these indicators and patients' quality of life remains inadequately explored, particularly in the Indian context. Objective: To investigate the relationship between psychological variables (depression, anxiety, illness intrusiveness, and quality of life) and physiological …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 Read article