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474 articles for “Clinical studies”
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A Python-Based Investigation of Clinical Data and Ultrasound Images for PCOS Diagnosis
Abstract: PCOS is a common endocrine disorder that impacts women in their reproductive years characterized by irregular menstrual cycles, hyperandrogenism, and polycystic ovaries. The full diagnostic plan is mainly a combination of a pelvic ultrasound besides blood tests of specific parameters that indicate the presence of PCOS. Since PCOS is a hard-to-diagnose widespread hormonal disorder, blood tests, symptoms, and other parameters with the help of a computer can form a new …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Speech Therapy in the Digital Age: Telepractice and Remote Interventions
Abstract: In the digital age, advancements in technology have revolutionized various aspects of healthcare, including speech therapy. This study explores the emergence and evolution of telepractice and remote interventions in speech therapy. Telepractice, interchangeably labelled as teletherapy or telehealth, denotes providing speech therapy services remotely using telecommunication technology. Its incorporation into speech therapy has broadened service accessibility, notably benefiting underserved or remote locales. Moreover, it has ensured uninterrupted care delivery during …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 42–46 Read article
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Systolic-Predominant Hypertension and the Aging Heart: A Cross-Sectional Study on LVH and Cardiovascular Riskss
Abstract: Background: Systolic-predominant hypertension, defined as a systolic blood pressure ≥140 mm Hg with diastolic pressure <90 mm Hg, is the most prevalent form of hypertension in the elderly. It arises primarily due to age-related arterial stiffening and baroreceptor dysfunction. Once considered a benign outcome of aging, systolic-predominant hypertension is now recognized as a major risk factor for cardiovascular morbidity and mortality. Aim and Objective: To evaluate the cardiac status and …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 13–24 Read article
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Activity Quantification of Lu-177 SPECT/CT Imaging for Calibration Factor Analysis in Clinical Radionuclide Dosimetry
Abstract: Purpose: To evaluate the calibration factor (CF) at three-time points with the same protocol & acquisition parameters for the images of Lu-177 activity, scanned by two different SPECT/CTs (GE & MEDISO) using a cylindrical Jaszczak phantom with cold inserts, filled with uniform activity in water and to analyze the changes in the calibration factor data with time. The purpose of the study is to quantitatively analyze the first step (calibration …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 2, 2024 · pp. 9–22 Read article
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Past Life Regression and Psychiatry: A Critical Analysis
Abstract: Past Life Regression (PLR) is a controversial therapeutic approach. It is done through hypnosis, which recovers memories of previous lives. Although PLR has gained some popularity in alternative medicine, it is heavily criticized in mainstream psychiatry. As the effects have not been empirically validated. This study provides a comprehensive exploration of Past Life Regression (PLR), offering insights into how it can be understood within the realm of psychiatry. It delves …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 2, 2025 Read article
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Algorithm for the prediction of cardiovascular disease (CVD)
Abstract: cardiovascular diseases (CVD) still claim a significant number of deaths globally and remain the number one killer with an annual death toll of nearly 17.9 million. While several medical advancements have been made, an early diagnosis is still hard to obtain, which often leads to worsening conditions and intricate treatment options. With the advancement of modern technology, Machine learning has demonstrated to be a miraculous tool which can greatly impact …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article
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Assessment of Diuretic Activity of Hydroalcoholic Extract of Matricaria Chamomilla (Linn.) and Its Phytochemical Analysis with Emphasis on Toxicology
Abstract: While the traditional medicines are derived from medicinal plants, minerals and organic matter, the herbal drugs are prepared from medicinal plants only. This current research work will be very beneficial in figuring out the Matricaria chamomilla leaves extract diuretic effect by determining the ions and electrolyte excreted by the animals using ion selective channel inhibition. The phytochemical screening results revealed that the after which it was observed whether the alkaloids …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 1–10 Read article
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Explainable Machine Learning Integrated with Polymer-Based Diagnostic Technologies for Liver Health Classification
Abstract: Early and reliable assessment of liver health is essential for timely treatment, yet most machine-learning approaches face limitations such as class imbalance and low clinical interpretability. This study proposes a polymer-integrated, explainable machine-learning framework that combines SMOTE-based data balancing, Logistic Regression, and XAI techniques (SHAP and LIME) for transparent liver-health classification. In addition to ML modelling, the study emphasizes the emerging role of polymer-based biosensors, microfluidic polymer chips, polymer nanomaterials, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 631–643 Read article
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Trauma- Its Transgenerational Inheritance and Associated Nuances in Perinatal Care: A Systematic Review
Abstract: The research is a systematic review of the existing clinical and animal studies pertaining to effects of trauma on immediate offsprings and its transgenerational inheritance. The research also summarises the current statistical data on perinatal care globally with special emphasis on India as a developing nation and the current strategies, government policies and international recommendations on maternal and child health as put forward in the Sustainable development goal 2030 by …
Published in International Journal of Children · Vol. 1, Issue 1, 2024 · pp. 37–45 Read article
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Development of a Machine Learning and Artificial Intelligence Based Model Aimed at Forecasting the Prognostic Impact of C-Reactive Protein in Myocarditis
Abstract: The specific role of inflammation markers in myocarditis remains uncertain. We investigated the diagnostic and prognostic significance of C-reactive protein (CRP) levels at the initial diagnosis among myocarditis patients. Our retrospective study enrolled patients clinically suspected (CS) or biopsy-proven (BP) with myocarditis, with available CRP data at diagnosis. We collected patient information, including clinical, laboratory, and imaging findings at diagnosis and follow-up visits. We utilized machine learning methods, specifically random …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 12–24 Read article
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A Short Review on Long-Term Effects of Botox on Neuronal Sprouting: Mechanisms and Its Clinical Implications
Abstract: Botulinum toxin (Botox) is extensively used for its ability to induce temporary muscle paralysis through inhibition of acetylcholine release at neuromuscular junctions. While its short-term effects are well documented, emerging evidence suggests that chronic use of Botox may trigger neuronal sprouting, a process that could have significant long-term implications. This review synthesizes current research on the mechanisms by which Botox induces nerve sprouting and evaluates the clinical outcomes associated with …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 72–87 Read article
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A Comprehensive Review of Analytical Method – Development and Method Validation of Digoxin Tablets
Abstract: The main objective of this review is to give an outline of the method development and validation process of digoxin, and this review covers the different types of spectroscopic and chromatographic techniques, such as HPLC, UHPLC-Tandem mass spectroscopy, TLC, and LC-MS. A novel method for the determination of digoxin in biological samples has been developed and validated, focusing on improving sensitivity, specificity, and reproducibility. The method was validated in terms …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 47–58 Read article
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Preparation, Spectral Characterization and Bio-Evaluation of Five and Seven Membered Ring Derivatives
Abstract: Many cyclic compounds are made of heterogeneous atoms that are good electron donors to be the basic nucleus in the basic structure of chemical drugs, so most drugs and vitamins take cyclic compounds as a basic material for the manufacture of drugs, and without a doubt these drugs are distinguished by their high ability to make many biologically active derivatives in the fields of biochemistry and clinical medicine. Universal studies …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 96–109 Read article
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Bioanalytical Method Development and Validation for the Estimation of Levothyroxine in Human K₃EDTA Plasma by Using UPLC-MS/MS
Abstract: A rapid, sensitive, and highly selective UPLC-MS/MS method was developed and validated for the quantitative estimation of Levothyroxine in human plasma using Levothyroxine-D₃ as the internal standard (IS). Chromatographic separation was achieved on a Gemini NX-C18 column (50 × 3.0 mm, 3 µm) with a mobile phase consisting of acetonitrile and water (70:30, v/v) containing 0.015% formic acid at a flow rate of 0.5 mL/min. The total run time was …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 32–46 Read article
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Intermittent Fasting: Exploring the Benefits and Risks of Intermittent Fasting for Weight Loss and Overall Health
Abstract: Perception in Intermittent Fasting: One novel approach for managing weight is intermittent fasting (IF) which is gaining more popularity in recent days. This research investigates advantages and disadvantages of IF with an emphasis on its impact on metabolic processes, cardiovascular health, cognitive abilities, and changes in hormone levels. Methods: A literature review comprising randomized clinical trials, cohort studies, and meta-analyses of peer-reviewed publications was performed. A resolution was obtained by …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 3, 2025 · pp. 24–29 Read article
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NanoBioAI: Utilizing Python to Investigate Magnetocaloric Effects in Magnetotactic Bacteria and Optimized Conditions for Thermotherapy
Abstract: The study presented in the research work represents a multidisciplinary approach, integrating biology, nanotechnology, and artificial intelligence. It specifically highlights the use of python computational power to investigate magnetocaloric effect (MCE) in magnetotactic bacteria (MTB), a phenomenon yet to be fully understood, characterized by reversible heating and cooling effects induced by magnetic fields. MTB are unique in that they contain embedded magnetic nanoparticles ranging from 10–100 nm in diameters. These …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 2, 2024 · pp. 122–131 Read article
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Evaluating the Role of Platelet Indices, with a Focus on Immature Platelet Fraction (IPF), in Differentiating Hyper-Destructive and Hypo-Productive Thrombocytopenia: A Study from Ludhiana, Punjab, India
Abstract: Background: Thrombocytopenia, characterized by a reduction in platelet count, is commonly observed in clinical settings. Its etiology can be broadly classified into hyper-destructive thrombocytopenia, where platelets are destroyed at an accelerated rate, and hypo-productive thrombocytopenia, where platelet production is impaired. Differentiating between these two causes is essential for effective management. The Immature Platelet Fraction (IPF) has emerged as a promising non-invasive diagnostic tool to distinguish these causes. Objectives: The primary …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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The Burden of Empirical Therapy: Analyzing the Predominance of Broad-Spectrum Antibiotic Usage in Lower Respiratory Tract Infections
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Epidemiology and Mycological Analysis of Superficial Mycosis in a Northern Indian Tertiary Care Hospital
Abstract: Background: A fungal infection that affects the outer layer of the skin and its connective tissue, including hair and nails, is called superficial mycosis. These infections are typically caused by fungi, which thrive on keratin, the proteinthat makes up the nails, hair, and skin. A common disease that can affect people of any age, gender, or race is superficial mycosis. Usually, it appears as a streaky red rash that can …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 1–12 Read article
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Infection Control awareness among Nursing students: Descriptive Insights from Ongoing Clinical Orientations in Odisha
Abstract: Background: Effective infection control practices are critical in preventing healthcare-associated infections (HAIs). Aim: This study aimed to assess the awareness regarding effective infection control measures among student nurses undertaking their initial clinical orientations at Hospitals. Method: The study accepted 64 respondents from II-year BSc Nursing, sampled in clusters from selected Hospitals, Odisha. Results: The students yielded a mean awareness score of 0.69, categorized as Good. A comparison revealed that female …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 15–20 Read article